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Choline supplementation restores substrate balance and alleviates complications of Pcyt2 deficiency.
Laila C Schenkel et al.
The Journal of nutritional biochemistry, 26(11), 1221-1234 (2015-08-06)
Choline plays a critical role in systemic lipid metabolism and hepatic function. Here we conducted a series of experiments to investigate the effect of choline supplementation on metabolically altered Pcyt2(+/-) mice. In Pcyt2(+/-) mice, the membrane phosphatidylethanolamine (PE) turnover is
Jonas Andersson et al.
Physics in medicine and biology, 56(2), 299-314 (2010-12-17)
A method to correct for the general recombination losses for liquid ionization chambers in continuous beams has been developed. The proposed method has been derived from Greening's theory for continuous beams and is based on measuring the signal from a
Nikolaos Kritikos et al.
Journal of chromatography. A, 1403, 70-80 (2015-06-06)
In the current study, quantitative structure-retention relationships (QSRR) were constructed based on data obtained by a LC-(ESI)-QTOF-MS/MS method for the determination of amino acid analogues, following their derivatization via chloroformate esters. Molecules were derivatized via n-propyl chloroformate/n-propanol mediated reaction. Derivatives
Dandan Ge et al.
Journal of chromatography. A, 1408, 56-62 (2015-07-22)
Acid oxidized multi-walled carbon nanotubes (CNTs) functionalized with chitosan were coated on polypropylene membrane and used as sorbent to extract trace polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) from environmental water samples. The analytes were extracted by the hydrophobic
Marina C Beaudry et al.
Environmental toxicology and chemistry, 34(9), 2051-2060 (2015-04-23)
Trophic position and body mass are traits commonly used to predict organochlorine burdens. Sharks, however, have a variety of feeding and life history strategies and metabolize lipid uniquely. Because of this diversity, and the lipid-association of organochlorines, the dynamics of
M Dolors Benaiges et al.
Biotechnology progress, 26(5), 1252-1258 (2010-10-15)
The characterization of the recombinant Candida rugosa Lip2 (r-Lip2) isoenzyme obtained from fed-batch cultures of Pichia pastoris under PAOX promoter was carried out, determining the optimal pH and temperature as well as their catalytic performance in both hydrolysis and synthesis
Mateus B Pereira et al.
Journal of AOAC International, 97(4), 987-994 (2014-08-26)
Pollution of water sources by pesticides is a result of intensive use of these compounds, and the establishment of analytical methods for monitoring programs is very important. This paper presents a method for the determination of multiclass pesticide residues in
Alexandre Démolis et al.
ChemSusChem, 10(12), 2612-2617 (2017-05-04)
This article reports a detailed study on the reactivity of levulinic acid and cellulose with 1-butene and iso-butene for the catalytic formation of sec- and tert-butyl levulinates. The influence of catalyst type and various solvent conditions have been investigated to
Pai-Shan Chen et al.
Journal of chromatography. A, 1395, 41-47 (2015-04-13)
An efficient and effective headspace microextraction technique named static headspace knotted hollow fiber microextraction (HS-K-HFME) has been developed for the determination of volatile organic compounds (VOCs) in water samples. The knot-shaped hollow fiber is filled with 25μL of the extraction
Choline acetate enhanced the catalytic performance of Candida rogusa lipase in AOT reverse micelles.
Luyan Xue et al.
Colloids and surfaces. B, Biointerfaces, 105, 81-86 (2013-01-29)
Choline acetate is an ionic liquid composed of a kosmotropic anion and a chaotropic cation. According to Hofmeister series, a kosmotropic anion and/or a chaotropic cation could stabilize an enzyme, thereby facilitating the retention of the catalytic activity of the
Hao Su et al.
Journal of chromatography. A, 1422, 334-339 (2015-11-03)
In this study, a stable cadmium(II)-based metal-organic framework (MOF) material was designed and used as a sorbent for the dispersive solid-phase extraction (dSPE) of polybrominated diphenyl ethers (PBDEs) in environmental water samples. Gas chromatography coupled with triple quadrupole mass spectrometer
Chronic nephrotoxicity of 2,2,4-trimethylpentane and other branched-chain hydrocarbons.
E A Lock
Toxicology letters, 53(1-2), 75-80 (1990-09-01)
Michał Szumski et al.
Journal of chromatography. A, 1373, 114-123 (2014-12-04)
A novel, cholesterol-based polymeric monolithic stationary phase for capillary liquid chromatography, was prepared by thermally initiated in-situ polymerization. Cholesteryl methacrylate (CholMA) was used as a functional monomer and trimethylolpropane trimethacrylate (TRIM) was a cross-linker, while azobisisobutyronitrile (AIBN) was an initiator.
Hana Stiborova et al.
The Science of the total environment, 533, 439-445 (2015-07-17)
Disposal of solid waste to landfills from waste water sewage treatment plants (WWTPs) serves as a potential source of contamination by polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCD). Native microbial communities have been found to degrade a variety of xenobiotics
Nibedita Pal et al.
Analytical chemistry, 83(20), 7736-7744 (2011-09-09)
Fluorescence correlation spectroscopy (FCS) is an ideal tool for measuring molecular diffusion and size under extremely dilute conditions. However, the power of FCS has not been utilized to its best to measure diffusion and size parameters of complex chemical systems.
Petter Olsson et al.
Lipids, 47(1), 93-99 (2011-11-22)
A new method for the separation and identification of lipid classes by normal-phase HPLC on a cyanopropyl column is described. The use of a simple binary gradient, with toluene as a component, provided a rapid separation of non-polar as well
Sumi Oh et al.
Journal of food science, 80(11), C2382-C2388 (2015-09-27)
Antioxidant properties of the aqueous extracts of hulled barley (Hordeum vulgare L.) that had been roasted at 210 °C for 20 min were determined in bulk oil and oil-in-water (O/W) emulsions. Bulk oils were heated at 60, 100, and 180
Md Mahabubur Rahman Talukder et al.
Applied biochemistry and biotechnology, 177(8), 1742-1752 (2015-09-17)
Although ultrasound has been used to accelerate many enzymatic reactions, the low stability of enzymes in such a system still remains a critical issue, limiting its industrial application. Here, we have reported that polyethylene glycol (PEG) pretreatment stabilized Chromobacterium viscosum
Oier Aizpurua-Olaizola et al.
Journal of food science, 80(1), E101-E107 (2014-12-05)
In this study, supercritical fluid extraction has been successfully applied to a sequential fractionation of fatty acids and polyphenols from wine wastes (2 different vitis vinifera grapes). To this aim, in a 1st step just fatty acids were extracted and
Sergey A Tovstun et al.
Journal of colloid and interface science, 351(2), 485-492 (2010-08-31)
The polydispersity of the reverse micelles is determined mainly by the fluctuations of their composition. The composition of the reverse micelle is a two-dimensional random variable whose components are the numbers of water (i) and surfactant (j) molecules. In this
Chong-Ki Lee et al.
Pharmacological reports : PR, 67(1), 44-51 (2015-01-07)
This study aimed to investigate the effects of HMG-CoA reductase inhibitors on the pharmacokinetics of nifedipine in rats. We determined the pharmacokinetic parameters of nifedipine and dehydronifedipine in rats after oral and intravenous administration of nifedipine without and with HMG-CoA
Stephanie J Church et al.
Biochemical and biophysical research communications, 460(3), 549-554 (2015-03-24)
Ob/ob mice provide an animal model for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH) in patients with obesity and type-2 diabetes. Low liver copper has been linked to hepatic lipid build-up (steatosis) in animals with systemic copper deficiency caused by low-copper
Claire Chen et al.
Endocrinology, 155(8), 2976-2985 (2014-06-01)
The ability of the central nervous system to synthesize steroid hormones has wide-ranging implications for physiology and pathology. Among the proposed roles of neurosteroids is the regulation of the LH surge. This involvement in the estrogen-positive feedback demonstrates the integration
Francisco Bueso et al.
Journal of biological engineering, 9, 12-12 (2015-07-28)
Extensive native Jatropha curcas L. (Jatropha) crop areas have been planted in Central America marginal lands since 2008 as a non-edible prospective feedstock alternative to high-value, edible palm oil. Jatropha biodiesel is currently exclusively produced in the region at commercial
Pierina Visciano et al.
Journal of food protection, 78(9), 1719-1728 (2015-09-01)
Concentrations of pollutants with regulatory limits were determined in specimens of Chamelea gallina, a species of clam collected along the Abruzzi coastal region of the central Adriatic Sea. Nine sampling sites were selected to evaluate the distribution of contaminants in
Silvia K Moreno-Forero et al.
The ISME journal, 9(1), 150-165 (2014-06-18)
The efficacy of inoculation of single pure bacterial cultures into complex microbiomes, for example, in order to achieve increased pollutant degradation rates in contaminated material (that is, bioaugmentation), has been frustrated by insufficient knowledge on the behaviour of the inoculated
Georgia Sanabria-Ortega et al.
Analytical chemistry, 84(18), 7874-7880 (2012-08-01)
A new method to determine Pb isotope ratio without ion-exchange-matrix separation is proposed. After acid digestion, Pb was ethylated to Et(4)Pb, separated from the digested solution (black shale, asphaltene, crude oil and kerogen) by extraction in isooctane, and then injected
William K Boyes et al.
Neurotoxicology and teratology, 32(5), 525-535 (2010-05-05)
The volatile organic compound 2,2,4-trimethylpentane (TMP, "isooctane") is a constituent of gasoline for which the current health effects data are insufficient to permit the US Environmental Protection Agency to conduct a risk assessment. The potential neurological impairment from acute inhalation
Peter Wardrop et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 990, 1-6 (2015-04-02)
Polybrominated diphenyl ethers (PBDEs) have become ubiquitous environmental contaminants due to their incorporation into many consumer products. Their ability to bioaccumulate to alarming levels in fat-rich matrices such as fish demands fast and efficient methods to monitor these contaminants. We
Xin Jin et al.
Enzyme and microbial technology, 48(6-7), 454-457 (2011-11-25)
The influence of reaction media on the racemic temperature (T(r)) in the lipase-catalyzed resolution of ketoprofen vinyl ester was investigated. An effective approach to the control of the enzymatic enantioselectivity and the prediction of the increasing tendency was developed based
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