CN
Search Within
40027
应用筛选条件
关键词:'40027'
显示 1-30 共 31 条结果 关于 "40027" 范围 论文
Javier C Waksman et al.
Clinics in occupational and environmental medicine, 4(3), 413-421 (2004-08-25)
This article presents the current knowledge and clinical applications of the use of biomarkers of exposure to the halogenated solvents 1,1,1 trichloroethane (methylchloroform), trichloroethylene, tetrachloroethylene (perchloroethylene), and 1,1 dichloroethylene (vinylidene chloride). Although some studies have shown that protein and DNA
Hiroyuki Ohno et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 46(1), 8-12 (2005-05-11)
A headspace GC/MS analysis method for the simultaneous determination of residual vinyl chloride (VC) and vinylidene chloride (VDC) in polyvinyl chloride (PVC) and polyvinylidene chloride (PVDC) products was developed. A test sample was swelled overnight with N,N-dimethylacetamide in a sealed
J V Bruckner et al.
The Journal of pharmacology and experimental therapeutics, 333(2), 519-527 (2010-02-05)
The objective of this investigation was to elucidate the effects of route of exposure and oral dosage regimen on the toxicokinetics (TK) of 1,1-dichloroethylene (DCE). Fasted male Sprague-Dawley rats that inhaled 100 or 300 ppm for 2 h absorbed total
1,1-Dichloroethylene.
Reviews of environmental contamination and toxicology, 106, 81-91 (1988-01-01)
Scott D Phillips et al.
Clinics in occupational and environmental medicine, 4(3), 423-443 (2004-08-25)
Vapor intrusion must be recognized appropriately as a separate pathway of contamination. Although many issues resemble those of other forms of contamination (particularly its entryway, which is similar to that of radon seepage), vapor intrusion stands apart as a unique
Kimberly N Heck et al.
Journal of the American Chemical Society, 130(49), 16592-16600 (2009-06-26)
Insight into the nature of transient reaction intermediates and mechanistic pathways involved in heterogeneously catalyzed chemical reactions is obtainable from a number of surface spectroscopic techniques. Carrying out these investigations under actual reaction conditions is preferred but remains challenging, especially
S Muralidhara et al.
Toxicological sciences : an official journal of the Society of Toxicology, 64(1), 135-145 (2001-10-19)
1,1-Dichloroethane (DCE) is a solvent that is often found as a contaminant of drinking water and a pollutant at hazardous waste sites. Information on its short- and long-term toxicity is so limited that the U.S. EPA and ATSDR have not
P G Forkert et al.
Drug metabolism and disposition: the biological fate of chemicals, 29(11), 1396-1402 (2001-10-17)
1,1-Dichloroethylene (DCE) causes hepatocellular necrosis that preferentially affects centrilobular hepatocytes. The cytotoxic lesion has been attributed to DCE oxidation mediated mainly by CYP2E1, resulting in formation of reactive intermediates including the DCE epoxide. Here, we have tested the hypothesis that
Chizuko Kageyama et al.
Archives of microbiology, 183(1), 56-65 (2004-12-01)
Two strains of trichloroethylene (TCE)-degrading bacteria were isolated from soils at polluted and unpolluted sites. The isolates, strains TE26(T) and K6, showed co-substrate-independent TCE-degrading activity. TCE degradation was accelerated by preincubation with tetrachloroethylene, cis-dichloroethylene (DCE) and 1,1-DCE. TCE-degrading activities of
P G Forkert
Experimental lung research, 24(4), 455-461 (1998-07-11)
This study investigates the potential of urethane-induced lung tumors to activate 1,1-dichloroethylene (DCE), a chemical that causes Clara cell damage in mice. Metabolism of DCE is catalyzed by the cytochrome P450 isozyme CYP2E1 to the DCE-epoxide, as assessed by formation
Masarin Ban et al.
Toxicology, 184(1), 41-50 (2002-12-31)
Using immunotoxic functional tests, namely IgM response to sheep red blood cells (SRBCs) and interferon-gamma (IFN-gamma) production, this study simultaneously evaluated the effects of inhaled chloroform (10, 20, and 50 ppm), carbon tetrachloride (100, 200, and 300 ppm), 1,1-dichloroethylene (5
Andrea C Simmonds et al.
Drug metabolism and disposition: the biological fate of chemicals, 32(9), 1032-1039 (2004-08-21)
1,1-Dichloroethylene (DCE) exposure to mice elicits lung toxicity that selectively targets bronchiolar Clara cells. The toxicity is mediated by DCE metabolites formed via cytochrome P450 metabolism. The primary metabolites formed are DCE epoxide, 2,2-dichloroacetaldehyde, and 2-chloroacetyl chloride. The major metabolite
H Ohno et al.
Food additives and contaminants, 23(8), 839-844 (2006-06-30)
A headspace gas chromatography/mass spectrometry method was developed for the simultaneous determination of vinylidene chloride and 1-chlorobutane in foods packaged with polyvinylidene chloride casing films. The solid foodstuff was homogenized with an equal mass of distilled water. The homogenate was
Erik J Martin et al.
The Journal of pharmacology and experimental therapeutics, 304(1), 121-129 (2002-12-20)
Hepatotoxicity induced by 1,1-dichloroethylene (DCE) is mediated by cytochrome P450-dependent metabolism to reactive intermediates, including the epoxide. We have tested the hypothesis that mitochondria are a primary target of toxicity by investigating dose- and time-dependent effects of DCE on mitochondrial
Juliet A Jones et al.
Chemical research in toxicology, 16(10), 1306-1317 (2003-10-21)
A proteome profiling approach was used to compare effects of two toxicants, 1,1-dicloroethylene (DCE) and diclofenac, which covalently adduct hepatic proteins. Bile was examined as a potential source of protein alterations since both toxicants target the hepatic biliary canaliculus. Bile
Xin Ma et al.
Water research, 40(6), 1155-1166 (2006-02-28)
Column experiments were performed to investigate a technology for remediating aquifers contaminated with chlorinated solvents. The technology involves installation of hollow-fiber membranes in the subsurface to supply hydrogen gas (H2) to groundwater to support biological reductive dechlorination in situ. Three
Adriana Olbert-Majkut et al.
Physical chemistry chemical physics : PCCP, 8(41), 4773-4782 (2006-10-18)
HONO/1,1-dichloroethylene/Ar matrices were subjected to UV radiation (lambda > 340 nm) from a medium pressure mercury lamp. The products of the photolysis were studied experimentally by means of FTIR spectroscopy and theoretically using the ab initio MP2 method. Two conformers
Keith A Canada et al.
Journal of bacteriology, 184(2), 344-349 (2001-12-26)
Trichloroethylene (TCE) is the most frequently detected groundwater contaminant, and 1-naphthol is an important chemical manufacturing intermediate. Directed evolution was used to increase the activity of toluene ortho-monooxygenase (TOM) of Burkholderia cepacia G4 for both chlorinated ethenes and naphthalene oxidation.
Larson.AR
Biohazards of Drinking Water Treatment (1988)
P G Forkert
Microscopy research and technique, 36(4), 234-242 (1997-02-15)
Exposure to 1,1-dichloroethylene (DCE) elicits lung and liver cytotoxicities that are manifested in bronchiolar Clara cell injury and centrilobular necrosis, respectively. The tissue damage is associated with cytochrome P450-dependent bioactivation of DCE to reactive intermediates, and is consistent with the
P G Forkert
Drug metabolism reviews, 33(1), 49-80 (2001-03-29)
Exposure to 1,1-dichloroethylene (DCE) causes lung and liver toxicities in mice. The lesions are characterized by damage preferentially to bronchiolar Clara cells in the lung and necrosis of centrilobular hepatocytes in the liver. The primary metabolites formed from DCE in
Linqiang Hua et al.
The journal of physical chemistry. A, 114(1), 37-44 (2009-12-22)
By using photofragment velocity imaging detection coupled with a (2 + 1) resonance-enhanced multiphoton ionization technique, the elimination channel of spin-orbit chlorine atoms in photodissociation of cis-, trans-, and 1,1-dichloroethylene at two photolysis wavelengths of 214.5 and 235 nm is
Stephen M Roberts et al.
Regulatory toxicology and pharmacology : RTP, 35(1), 44-55 (2002-02-16)
The U.S. Environmental Protection Agency has classified 1,1-dichloroethylene (vinylidene chloride; VDC) as a "C" carcinogen and has developed an inhalation unit risk value and an oral cancer slope factor for this chemical. The development and use of these cancer potency
Shaily Mahendra et al.
Chemosphere, 91(1), 88-92 (2012-12-15)
1,4-Dioxane (dioxane), a probable human carcinogen, is used as a solvent stabilizer for 1,1,1-trichloroethane (TCA) and other chlorinated solvents. Consequently, TCA and its abiotic breakdown product 1,1-dichloroethene (DCE) are common co-contaminants of dioxane in groundwater. The aerobic degradation of dioxane
Young Kim et al.
Biotechnology and bioengineering, 80(5), 498-508 (2002-10-02)
Batch kinetic and inhibition studies were performed for the aerobic cometabolism of 1,1,1-trichloroethane (1,1,1-TCA), 1,1-dichloroethylene (1,1-DCE), and 1,1-dichloroethane (1,1-DCA) by a butane-grown mixed culture. These chlorinated aliphatic hydrocarbons (CAHs) are often found together as cocontaminants in groundwater. The maximum degradation
Masarin Ban et al.
Toxicology, 226(2-3), 161-171 (2006-08-02)
Occupational allergy and asthma is a challenging issue in the developing countries. Chemicals inhaled in the workplaces may act not only as allergens but also as immune response modifiers, contributing to asthma exacerbation. In this study, we tested the adjuvant
Daniel B Cope et al.
Environmental science & technology, 43(1), 169-175 (2009-02-13)
A feasibility study was conducted using slags from six grey-iron foundries to evaluate their potential as reactive media for permeable reactive barriers (PRBs) to remove aqueous trichloroethylene (TCE) from groundwater. Batch tests indicated that the slags exhibit varying degrees of
Erik J Martin et al.
The Journal of pharmacology and experimental therapeutics, 313(1), 95-103 (2005-01-01)
1,1-Dichloroethylene (DCE) causes pulmonary injury that is characterized by necrosis of bronchiolar Clara cells. Mitochondria have been identified as an early target in the toxic response. Because mitochondria have been implicated in both necrotic and apoptotic cell death, we have
William Slikker et al.
Toxicology and applied pharmacology, 201(3), 226-294 (2004-12-08)
Experience with dose response and mechanisms of toxicity has shown that multiple mechanisms may exist for a single agent along the continuum of the full dose-response curve. It is highly likely that critical, limiting steps in any given mechanistic pathway
Jingling Zhang et al.
Environmental science & technology, 40(6), 1830-1836 (2006-03-31)
A microbial culture derived from a landfill site in Dover, DE consistently reduced trichloroethene (TCE) to ethene through 1,1-dichloroethene (DCE) as a dominant intermediate in the presence of ampicillin. A constant 1,1-DCE-to-cis-DCE ratio of 2.4 +/- 0.3 was observed for
1/2