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Ashley R Winslow et al.
Brain : a journal of neurology, 137(Pt 7), 1958-1970 (2014-05-27)
A growing number of PSEN1 mutations have been associated with dementia with Lewy bodies and familial Alzheimer's disease with concomitant α-synuclein pathology. The objective of this study was to determine if PSEN1 plays a direct role in the development of
Joanna Stafiej et al.
Experimental and therapeutic medicine, 13(3), 1057-1063 (2017-04-30)
Pseudoexfoliation syndrome (PEX) is an age-associated, sight disorder affecting elastic fibers in the eye and visceral organs but its exact etiology remains unknown. The purpose of the current study was to determine the morphology and ultrastructure of lens epithelial cells
Pengpeng Fan et al.
Physical chemistry chemical physics : PCCP, 22(3), 1097-1106 (2020-01-03)
Supported ionic liquids (ILs) are attractive alternatives for CO2 capture and the thickness of supported IL films plays a critical role in the CO2 mass transfer rate. However, the dependence of CO2 uptake on the IL film thickness differs as
Vinod Vellora Thekkae Padil et al.
Journal of agricultural and food chemistry, 63(14), 3757-3765 (2015-03-24)
Esterifications of the tree-based gum, gum karaya (GK), using dodecenylsuccinic anhydride (DDSA) were carried out in aqueous solutions. GK was deacetylated using alkali treatment to obtain deacetylated gum karaya (DGK). The DGK and its DDSA derivative were characterized using gel
Yingying Fu et al.
eLife, 9 (2020-08-05)
Although many high-risk mucosal and cutaneous human papillomaviruses (HPVs) theoretically have the potential to synthesize L1 isoforms differing in length, previous seroepidemiological studies only focused on the short L1 variants, co-assembling with L2 to infectious virions. Using the multimammate mouse
Magnetic microreactors for efficient and reliable magnetic nanoparticle surface functionalization
Digigow RG, et al.
Lab on a chip, 14(13), 2276-2286 (2014)
Maxime Chantreau et al.
The Plant cell, 26(11), 4462-4482 (2014-11-09)
Histochemical screening of a flax ethyl methanesulfonate population led to the identification of 93 independent M2 mutant families showing ectopic lignification in the secondary cell wall of stem bast fibers. We named this core collection the Linum usitatissimum (flax) lbf
Dodecenylsuccinic anhydride modified chitosan hydrogels for the sustained delivery of hydrophobic drugs. The case of thymol buccal delivery
Alvarez Echazu, et al.
Journal of Applied Polymer Science, 139, 51432-51432 (2022)
G Yu Vasyukov et al.
Bulletin of experimental biology and medicine, 163(1), 99-104 (2017-06-04)
We studied the effects of single administration of a suspension of magnetomicelles based on carbon-coated iron nanoparticles on the structure of rat lungs within 40 days. Histological analysis revealed a complex of hemodynamic alterations in the lungs. Described changes persisted
Ankita Sharma et al.
European journal of pharmacology, 882, 173244-173244 (2020-06-12)
Non-alcoholic fatty liver disease is emanating as a global cataclysm. This study was designed to investigate the antioxidative, anti-inflammatory and fat metabolism-regulating potential of berbamine (BBM), a natural bis-benzylisoquinoline alkaloid. BBM attenuated intracellular lipid accumulation in oleic-acid exposed HepG2 cells
Dennis Nurjadi et al.
Microorganisms, 8(10) (2020-10-22)
In times of spreading multidrug-resistant bacteria, species identification and decontamination of cell cultures can be challenging. Here, we describe a mobile cell culture contaminant with "black dot"-like microscopic appearance in newly established irreplaceable hybridoma cell lines and its identification. Using
Micha Simon et al.
Journal of neuroinflammation, 15(1), 225-225 (2018-08-14)
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) for which several new treatment options were recently introduced. Among them is the monoclonal anti-CD52 antibody alemtuzumab that depletes mainly B cells and T cells in
Mariana Seke et al.
Nanotechnology, 27(48), 485101-485101 (2016-11-05)
Fullerenol (C
Nastasia V Kosheleva et al.
Scientific reports, 10(1), 12614-12614 (2020-07-30)
Biological self-assembly is crucial in the processes of development, tissue regeneration, and maturation of bioprinted tissue-engineered constructions. The cell aggregates-spheroids-have become widely used model objects in the study of this phenomenon. Existing approaches describe the fusion of cell aggregates by
Radwanul Hasan Siddique et al.
Scientific reports, 6, 36204-36204 (2016-11-03)
The butterfly genus Hypolimnas features iridescent blue colouration in some areas of its dorsal wings. Here, we analyse the mechanisms responsible for such colouration on the dorsal wings of Hypolimnas salmacis and experimentally demonstrate that the lower thin lamina in
Kimberly S Butler et al.
Mutagenesis, 30(4), 577-591 (2015-05-13)
The focus of this research was to develop a better understanding of the pertinent physico-chemical properties of silver nanoparticles (AgNPs) that affect genotoxicity, specifically how cellular uptake influences a genotoxic cell response. The genotoxicity of AgNPs was assessed for three
Marjolein Meinders et al.
Blood, 125(12), 1957-1967 (2014-12-30)
Sp1 and Sp3 belong to the specificity proteins (Sp)/Krüppel-like transcription factor family. They are closely related, ubiquitously expressed, and recognize G-rich DNA motifs. They are thought to regulate generic processes such as cell-cycle and growth control, metabolic pathways, and apoptosis.
Jeanette Bannoehr et al.
PloS one, 15(3), e0225901-e0225901 (2020-03-03)
Hereditary nasal parakeratosis (HNPK) is an inherited disorder described in Labrador Retrievers and Greyhounds. It has been associated with breed-specific variants in the SUV39H2 gene encoding a histone 3 methyltransferase involved in epigenetic silencing. Formalin-fixed biopsies of the nasal planum
Experimental study on the surface properties of nanoalumina-filled epoxy resin nanocomposites
Deesy Pinto, et al.
Applied Sciences, 10, 733-733 (2020)
Shweta Suiwal et al.
Journal of immunological methods, 444, 7-16 (2017-02-18)
Correlating light microscopic immunolabelling results with electron microscopic data is of great interest in many fields of biomedical research but typically requires very specialized, expensive equipment and complex procedures which are not available in most labs. In this technical study
Dodecenylsuccinic anhydride modified collagen hydrogels loaded with simvastatin as skin wound dressings
Christian E Olivetti, et al.
Journal of Biomedical Materials Research Part A, 107, 1999-2012 (2019)
A A Gorkun et al.
Biomedical materials (Bristol, England), 13(4), 044108-044108 (2018-05-04)
One of the essential goals in regenerative medicine is microvascularization which enables an effective blood supply within de novo constructed tissues and organs. In our study, we used two common multipotent mesenchymal stromal cell (MMSC) sources (subcutaneous adipose tissue and
Ivana Kutle et al.
Scientific reports, 7(1), 15588-15588 (2017-11-16)
Cell rounding is a hallmark of the cytopathic effect induced by cytomegaloviruses. By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutant was identified that did not elicit cell rounding and lacked the ability to form typical
Fan He et al.
The Journal of endocrinology, 223(2), 167-180 (2014-09-12)
Both self-renewal and lineage-specific differentiation of mesenchymal stem cells (MSCs) are triggered by their in vivo microenvironment including the extracellular matrix (ECM) and secreted hormones. The ECM may modulate the physiological functions of hormones by providing binding sites and by
Meiyu Wu et al.
International journal of nanomedicine, 14, 4247-4259 (2019-06-27)
Purpose: Silver nanoparticles (AgNPs) have been widely applied in various fields as excellent antibacterial reagents over the past decades. Although the particle size is considered as the most crucial factor influencing cellular uptake, transportation, and accumulation behaviors, there are still
Lidija Zolotarevski et al.
Cutaneous and ocular toxicology, 35(1), 41-48 (2015-02-25)
Skin is the target of both acute and chronic exposure to warfarin, coumarin anticoagulant. Single exposure of rat skin to this agent induces early (24 h following epicutaneous administration) local response which might be part of inflammatory/reparatory homeostatic program or introduction
Ji-Geng Yan et al.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 24(12), 2759-2773 (2015-10-05)
Insidious cumulative brain injury from motor vehicle-induced whole-body vibration (MV-WBV) has not yet been studied. The objective of the present study is to validate whether whole-body vibration for long periods causes cumulative brain injury and impairment of the cerebral function.
Carlo Porfido et al.
Environmental science & technology, 53(18), 10961-10968 (2019-08-03)
Combined X-ray-based spectroscopy techniques were applied to investigate arsenic (As) bioaccumulation in earthworms (Eisenia andrei) exposed to six field-collected polluted soils (58-13 330 mg As kg-1). After 14 days of exposure to the arsenious soils, the As distribution in earthworms was
Ariane Saliani et al.
NeuroImage, 202, 116156-116156 (2019-09-07)
Atlases of the central nervous system are essential for understanding the pathophysiology of neurological diseases, which remains one of the greatest challenges in neuroscience research today. These atlases provide insight into the underlying white matter microstructure and have been created
Rong An et al.
Physical chemistry chemical physics : PCCP, 22(26), 14941-14952 (2020-06-27)
The nanofriction coefficient of ionic liquids (ILs), 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIM][BF4]) and 1-butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]), on the surfaces of mica and graphite was investigated using atomic force microscopy (AFM). A pronounced layered spatial distribution was found in the IL film formed
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