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Copy number variation in the complement factor H-related genes and age-related macular degeneration.
Katharina E Kubista et al.
Molecular vision, 17, 2080-2092 (2011-08-19)
To determine the contribution of copy number variation (CNV) in the regulation of complement activation (RCA) locus to the development of age-related macular degeneration (AMD). A multiplex ligation-dependent probe amplification assay was developed to quantify the number of copies of
Klaus Reither et al.
The Journal of infection, 70(4), 392-399 (2014-10-15)
Following endorsement by the World Health Organisation, the Xpert MTB/RIF assay has been widely incorporated into algorithms for the diagnosis of adult tuberculosis (TB). However, data on its performance in children remain scarce. This prospective, multi-centre study evaluated the performance
Ellyn E Ritchie et al.
Chemosphere, 90(7), 2129-2135 (2012-12-06)
Soil eco-toxicity testing was conducted in support of Canada's Chemical Management Plan (CMP) to fill data gaps for organic chemicals known to primarily partition to soil, and of which the persistence and inherent toxicity are uncertain. Two compounds representative of
S Reich et al.
Blood, 96(10), 3357-3363 (2000-11-09)
The butyrate derivative isobutyramide (IBT) increases fetal hemoglobin (HbF) in patients with beta-hemoglobinopathies, but little is known about its usefulness for prolonged therapeutic use. We treated 8 patients with transfusion-dependent beta-thalassemia with 350 mg/kg of body weight per day of
Clayton A Peimer et al.
The Journal of hand surgery, 38(1), 12-22 (2012-12-04)
To evaluate long-term efficacy and safety of collagenase clostridium histolyticum (CCH) after the third year of a 5-year nontreatment follow-up study, Collagenase Option for Reduction of Dupuytren Long-Term Evaluation of Safety Study. This study enrolled Dupuytren contracture patients from 5
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