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Gang Zheng et al.
Toxicology letters, 225(1), 110-118 (2013-12-10)
The blood-cerebrospinal fluid barrier (BCB) plays a key role in maintaining copper (Cu) homeostasis in the brain. Cumulative evidences indicate that lead (Pb) exposure alters cerebral Cu homeostasis, which may underlie the development of neurodegenerative diseases. This study investigated the
Chunping Li et al.
Clinical toxicology (Philadelphia, Pa.), 51(4), 225-229 (2013-03-27)
Occupational and environmental exposures to lead (Pb) are a worldwide concern. DNA methylation plays an important role in the development of Pb toxicity. Here, we try to find out the evidence to prove that the methylation of the LINE-1 promoter
Jianping Zhang et al.
Toxicology letters, 218(3), 273-280 (2013-02-23)
Exposure to lead (Pb) can induce kidney damage, which is related to induction of oxidative damage and disturbance of intracellular calcium homeostasis. Pb can readily permeate through dihydropyridine-sensitive L-type calcium channels and accumulate within cells. The objective of this study
A Rahman et al.
Acta biologica Hungarica, 63(4), 411-425 (2012-11-09)
Cognitive impairment is a common feature of both lead exposure and hyperphosphorylation of tau. We, therefore, investigated whether lead exposure would induce tau hyperphosphorylation. Wistar rat pups were exposed to 0.2% lead acetate via their dams' drinking water from postnatal
Nabila Haddou et al.
Chemosphere, 107, 304-310 (2014-01-28)
The Gliding Arc Discharge (GAD) is an efficient non-thermal plasma technique able to degrade organic compounds dispersed in water at atmospheric pressure. The degradation of the organometallic lead acetate (PbAc) in aqueous solution was performed by two distinct plasmageneous processes:
Tahere Farkhondeh et al.
Cardiovascular & hematological disorders drug targets, 13(1), 45-49 (2012-10-04)
This study was aimed to examine the effect of lead acetate on inflammatory biomarkers in blood of guinea pigs in comparison with sensitized animals. Thirty guinea pigs were randomly allocated into control (group C), sensitized (group S), and three Pb-exposed
M Nisanian et al.
Poultry science, 93(4), 891-897 (2014-04-08)
Heavy metals have been implicated for their ability to increase antibiotic resistance in bacteria collected from polluted waters, independent of antibiotic exposure. Specific-pathogen-free Leghorn chickens were therefore given Pb acetate in the drinking water to expose the enteric bacteria to
J S Schneider et al.
Toxicology letters, 217(1), 75-81 (2012-12-19)
Developmental exposure to lead (Pb) has adverse effects on cognitive functioning and behavior that can persist into adulthood. Exposures that occur during fetal or early life periods may produce changes in brain related to physiological re-programming from an epigenetic influence
Fengwei Tian et al.
Biological trace element research, 150(1-3), 264-271 (2012-06-12)
Lead causes a broad range of adverse effects in humans and animals. The objective was to evaluate the potency of lactobacilli to bind lead in vitro and the protective effects of a selected Lactobacillus plantarum CCFM8661 against lead-induced toxicity in
Asit Rai et al.
Toxicology mechanisms and methods, 23(2), 99-107 (2012-08-21)
Exposure to a mixture of As, Pb and Cd induces apoptosis and morphological alterations in the cortical astrocytes of rat brain. The levels of the glial fibrillary acidic protein (GFAP) undergo a reduction. The GFAP exists in several isoforms, viz.
I Baranowska-Bosiacka et al.
Toxicology, 303, 187-200 (2012-11-14)
The aim of this paper is to examine if pre- and neonatal exposure to lead (Pb) may intensify or inhibit apoptosis or necroptosis in the developing rat brain. Pregnant experimental females received 0.1% lead acetate (PbAc) in drinking water from
Mohammad Hossein Boskabady et al.
Ecotoxicology and environmental safety, 86, 233-238 (2012-10-24)
The association between lead exposure and asthma is controversial. The effect of inhaled lead acetate on lung inflammation, tracheal responsiveness and immune components in guinea pigs after sensitization was examined in this study. Five groups of guinea pigs were randomly
Yuan-Yuan Li et al.
Environmental toxicology, 27(8), 495-502 (2012-07-06)
It has been suggested that lead (Pb) exposure in early life may increase amyloid precursor protein (APP) expression and promote the pathogenesis of Alzheimer's disease in old age. The current study examined whether the DNA methylation patterns of APP gene
Cragg, R. H.; Weston, A. F.
Tetrahedron Letters, 655-655 (1973)
Samuel Greani et al.
Comptes rendus biologies, 335(10-11), 657-667 (2012-12-04)
The ultrastructural organization of the female reproductive system of Metadena depressa, digenean intestinal parasite of Sparidae (Dentex dentex), was investigated by electron microscopy. The vitellogenesis is divided into four stages: stage I, vitellocytes have a cytoplasm mainly filled with ribosomes
Photostability of colloidal PbSe and PbSe/PbS core/shell nanocrystals in solution and in the solid state.
Stouwdam JW, et al.
The Journal of Physical Chemistry C, 111(3), 1086-1092 (2007)
Sangeeta Chatterjee et al.
FEBS letters, 587(5), 474-480 (2013-01-30)
The human heme-regulated eIF2α kinase, also called the human heme-regulated inhibitor (hHRI) is significantly up-regulated particularly at the level of translation during stress. In this report we show that during lead-stress, the regulation of hHRI mRNA translation is mediated through
Gagan Flora et al.
Biological trace element research, 152(1), 31-40 (2013-01-08)
Chronic lead exposure is associated with several health disorders in humans and animals. Lead exposure leads to the generation of reactive oxygen species and depletes body antioxidant enzymes causing damage to various macromolecules and ultimately cell death. Curcumin has been
Designing PbSe nanowires and nanorings through oriented attachment of nanoparticles.
Cho K-S, et al.
Journal of the American Chemical Society, 127(19), 7140-7147 (2005)
Anke Visan et al.
Neurotoxicology, 33(5), 1135-1146 (2012-06-27)
Mouse embryonic stem cells (mESCs) represent an attractive cellular system for in vitro studies in developmental biology as well as toxicology because of their potential to differentiate into all fetal cell lineages. The present study aims to establish an in
Somayeh Hosseinzadeh et al.
Pharmaceutical biology, 51(2), 240-245 (2012-11-09)
For many years it has been known that lead is life-threatening, not only as an air pollutant but also because of it has been associated with several conditions including neurodegenerative disease. Curcumin (the principal curcuminoid found in turmeric) has demonstrated
Christina Sobin et al.
Toxicology letters, 220(1), 44-52 (2013-04-20)
The mechanisms by which early chronic lead (Pb) exposure alter brain development have not been identified. We examined neuroimmune system effects in C57BL/6J mice with Pb exposure, including levels that may be common among children in lower socioeconomic income environments.
Epigenetic histone modification regulates developmental lead exposure induced hyperactivity in rats.
Man Luo et al.
Toxicology letters, 225(1), 78-85 (2013-12-03)
Lead (Pb) exposure was commonly considered as a high environmental risk factor for the development of attention-deficit/hyperactivity disorder (ADHD). However, the molecular basis of this pathological process still remains elusive. In light of the role of epigenetics in modulating the
Shu Guo et al.
Toxicology letters, 229(1), 150-157 (2014-06-25)
The demonstration of bystander effect, which means injured cells propagate damage to neighboring cells, in whole organisms has clear implication of the potential relevance of the non-targeted response to human health. Here we show that 10 μM lead acetate, the
Qinghua Jia et al.
Toxicology mechanisms and methods, 22(9), 705-710 (2012-08-17)
Lead-induced nephrotoxicity is a human health hazard problem. In this study, Human mesangial cells (HMCs) were treated with different concentration of lead acetate (5, 10, 20 μmol/l) in order to investigate the oxidative stress and apoptotic changes. It was revealed
Simple cubic super crystals containing PbTe nanocubes and their core- shell building blocks.
Zhang J, et al.
Journal of the American Chemical Society, 130(45), 15203-15209 (2008)
Anne E Roberts et al.
Ecotoxicology and environmental safety, 102, 100-104 (2014-02-11)
The effect of lead accumulation on photopigment production, mineral nutrition, and Anabaena vegetative cell size and heterocyst formation in Azolla caroliniana was investigated. Plants were exposed to 0, 1, 5, 10, and 20 mg L(-1) lead acetate for ten days.
Nilantika Paul et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 105-112 (2014-04-22)
Lead has no known role in the body that is physiologically relevant, and its harmful effects are myriad. Lead from the atmosphere and soil ends up in water bodies thus affecting the aquatic organisms. This situation has thus prompted numerous
High-energy density of Pb0. 97La0. 02 (Zr0. 50Sn0. 45Ti0. 05) O3 antiferroelectric ceramics prepared by sol-gel method with low-cost dibutyltin oxide.
Dan Y, et al.
Journal of the American Ceramic Society. American Ceramic Society, 0(0) (2018)
Mohammed H Badawoud et al.
Neurosciences (Riyadh, Saudi Arabia), 18(1), 52-57 (2013-01-08)
To investigate the morphological changes in the peripheral motor system of the rat induced by exposure to lead. This study was conducted at the Anatomy Department, Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia from January 2011
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