Merck
CN
Search Within

48079

应用筛选条件
关键词:'48079'
显示 1-30 共 48 条结果 关于 "48079" 范围 论文
Emanuela Micheli et al.
Mini reviews in medicinal chemistry, 9(14), 1622-1632 (2010-01-22)
The search for telomerase inhibitors has been widely explored in the last few years, since telomerase activity in somatic cells can be considered as a general cancer mark. One of the possible strategies is the capping of telomere 3'-end (the
Daniel Aigner et al.
Chemical communications (Cambridge, England), 49(21), 2139-2141 (2013-02-08)
Novel pH sensors relying on 1-aminoperylene bisimide dyes covalently grafted onto cross-linked poly(acryloylmorpholine) are presented. They feature fluorescence in the near infra-red range and a large Stokes shift (>90 nm).
Jinfeng Zhang et al.
Chemical communications (Cambridge, England), 49(73), 8072-8074 (2013-08-03)
We demonstrate a new strategy for preparing photosensitizer-doped perylene nanoparticles via doping, fluorescence resonance energy transfer, and antenna effect for simultaneous enhanced diagnosis and photodynamic therapy.
Lindsay M Leone et al.
The Journal of chemical physics, 138(12), 12A524-12A524 (2013-04-06)
The rotational dynamics of three perylene diimide dyes are studied on the single molecule (SM) level in ortho-terphenyl (OTP) near the glass transition temperature (T(g)). At all temperatures probed, spanning 1.03-1.06 T(g), each of the three probes exhibits rotational correlation
Emilio Russo et al.
Phytotherapy research : PTR, 28(5), 643-655 (2013-07-31)
Hypericum perforatum (HP) belongs to the Hypericaceae family and is one of the oldest used and most extensively investigated medicinal herbs. The medicinal form comprises the leaves and flowering tops of which the primary ingredients of interest are naphthodianthrones, xanthones
M Barra et al.
Biochimica et biophysica acta, 1830(9), 4365-4373 (2012-12-12)
There is no doubt that future discoveries in the field of biochemistry will depend on the implementation of novel biosensing techniques, able to record biophysiological events with minimal biological interference. In this respect, organic electronics may represent an important new
Margaret E Daub et al.
Antioxidants & redox signaling, 19(9), 970-989 (2012-12-25)
Reactive oxygen species (ROS) play multiple roles in interactions between plants and microbes, both as host defense mechanisms and as mediators of pathogenic and symbiotic associations. One source of ROS in these interactions are photoactivated, ROS-generating perylenequinone pigments produced via
Noha Nafee et al.
International journal of pharmaceutics, 454(1), 249-258 (2013-07-10)
Hypericin (HY) is a naturally-occurring, potent photosensitizer. However, its lipophilicity limits its therapeutic applications. Our attempt is, thus, to develop a biodegradable nanocarrier for hypericin capable of preserving its antibacterial photoactivity. Amphiphilic block copolymers were synthesized to prepare hypericin-laden nanoparticles
G Boobalan et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 113, 340-345 (2013-06-08)
Perylene bisimides form a unique class of organic semiconductors, in this investigation two symmetrical perylene bisimides caped with 1-butyl (B-PTCDI) and 4,4-diethoxybutyl (DB-PTCDI) have been synthesized and characterized. The compounds self-assembled as a network of nanobelts and nanorods in the
Mykhaylo Myahkostupov et al.
The Journal of organic chemistry, 78(17), 8634-8644 (2013-08-15)
We have synthesized and thoroughly characterized two representative ladder-type acetylene-bridged perylenediimide dimers bearing long alkyl chain solubilizing groups, bis[1-ethynyl-N,N'-bis(1-hexylheptyl)-perylene-3,4:9,10-tetracarboxylic diimide] ([PDICC]2, 1) and 1,1'-ethynyl-bis[N,N'-bis(1-hexylheptyl)-perylene-3,4:9,10-tetracarboxylic diimide] ([PDI]2CC, 2). In these dimeric PDI molecules, NMR-based structural characterization became nontrivial because severe (1)H
Lucia Balogová et al.
General physiology and biophysics, 32(2), 179-187 (2013-03-13)
Apoptosis is a key process in the development and maintenance of tissue homeostasis. This process of controlled cell death is tightly regulated by a balance between cell survival and damage signals. We focused our attention towards one apoptotic pathway, the
Determination of polynuclear aromatic hydrocarbons in water by flotation enrichment and HPLC
Bo-Xing X and Yu-Zhi F
Talanta, 35(11), 891-894 (1988)
H Yang et al.
Physical chemistry chemical physics : PCCP, 15(14), 4939-4946 (2013-02-27)
Scanning Tunneling Microscopy (STM), Scanning Tunneling Spectroscopy (STS), and manipulation studies were performed on an ordered self-assembled monolayer (SAM) of N,N'-bis(1-hexylheptyl)perylene-3,4:9,10-bis(dicarboximide) molecules on epitaxial graphene on hexagonal silicon carbide - SiC(0001). Four novel aspects of the molecular SAM on graphene
Hongbo Li et al.
Analytica chimica acta, 766, 47-52 (2013-02-23)
A novel visible light sensitized photoelectrochemical sensing platform was constructed based on the perylene-3,4,9,10-tetracarboxylic acid/titanium dioxide (PTCA/TiO(2)) heterojunction as the photoelectric beacon. PTCA was synthesized via facile steps of hydrolysis and neutralization reaction, and then the PTCA/TiO(2) heterojunction was easily
Márcia I Souza et al.
The journal of physical chemistry. B, 117(9), 2605-2614 (2013-02-14)
Hypericin is a photosensitizer with promising applications in photodynamic therapy (PDT) for cancer and infectious diseases treatments. Herein, we present a basic research study of L-diphenylalanine micro/nanotubes (FF-NTs) functionalized with hypericin. The system has special properties according to the hypericin
Marcelo G Vivas et al.
The journal of physical chemistry. B, 117(9), 2742-2747 (2013-02-07)
Herein, we report on the theoretical-experimental analysis of the two-photon absorption (TPA) and two-photon circular-linear dichroism (TPCLD) spectra of a highly conjugated, rigid, and centrosymmetric molecule in solution, that is, perylene/CH2Cl2. We show how a three-energy-level diagram, under the sum-over-essential
Comment on "The structure and formation of hydrogen-bonded molecular networks on Au(111) surfaces revealed by scanning tunnelling and torsional-tapping atomic force microscopy" by V. V. Korolkov, N. Mullin, S. Allen, C. J. Roberts, J. K. Hobbs and S. J. B. Tendler, Phys. Chem. Chem. Phys., 2012, 14, 15909.
Izabela Cebula et al.
Physical chemistry chemical physics : PCCP, 15(33), 14126-14127 (2013-06-27)
Yuan Jiang et al.
International journal of radiation biology, 90(7), 575-579 (2014-03-26)
In the present study, we investigated effects of photodynamic therapy with hypocrellin B on apoptosis, adhesion, and migration of cancer cells in vitro. Human ovarian cancer HO-8910 cell as a cancer model cell was incubated with hypocrellin B at a
Alessandro Sanguineti et al.
Chemical communications (Cambridge, England), 49(16), 1618-1620 (2013-01-23)
Highly efficient plastic based single layer Luminescent Solar Concentrators (LSCs) require the design of luminophores having complete spectral separation between absorption and emission spectra (large Stokes shift). We describe the design, synthesis and characterization of a new perylene dye possessing
Nobuaki Soh et al.
Talanta, 85(3), 1233-1237 (2011-08-03)
Perylene bisimide (PBI) is a fluorescent dye which has strong emission and high photostability. Although PBI has been widely used for industrial materials, the application of PBI in analytical fields was limited mainly due to its high hydrophobicity. In recent
Anish Babu et al.
Journal of biomedical nanotechnology, 9(2), 177-192 (2013-05-01)
The present study focused on the development of a novel biodegradable nanoparticle system based on polyethyleneglycol-modified gelatin (PEG-GEL) and polylactic acid (PLA) biopolymers for improving the photodynamic efficacy of cyclohexane-1,2-diamino hypocrellin B (CHA2HB), a potent photodynamic therapeutic (PDT) agent. The
Rozhin Penjweini et al.
Journal of photochemistry and photobiology. B, Biology, 120, 120-129 (2013-02-05)
Conventional photodynamic diagnosis (PDD) and therapy (PDT) makes use of photosensitizers that are excited by continuous light irradiation of specific wavelengths. In the case of PDT, the overdose of continuous excitation may lead to an expansion of necrosis in cancer
Yishi Wu et al.
The journal of physical chemistry. A, 117(8), 1712-1720 (2013-02-09)
The first example of donor-linked di(perylene bisimide)s is reported. UV-vis absorption spectra of these newly synthesized dyads showed intense absorption across the entire visible region, demonstrating their excellent light-harvesting activities. The severe fluorescence quenching event probed by steady-state fluorescence spectroscopy
Mustafa Supur et al.
Physical chemistry chemical physics : PCCP, 15(7), 2539-2546 (2013-01-17)
Photodriven electron-transport properties of the self-assemblies of N,N'-di(2-(trimethylammoniumiodide)ethylene)perylenediimide stacks (TAIPDI)(n) with three electron donors, disodium 4,4'-bis(2-sulfonatostyryl)biphenyl (BSSBP, stilbene-420), sodium 9,10-dimethoxyanthracene-2-sulfonate (DANS) and disodium 6-amino-1,3-naphthalenedisulfonate (ANADS) have been studied in water. These electron donors vary in their π-extent to adjust the
Z Ocak et al.
European review for medical and pharmacological sciences, 17(9), 1185-1190 (2013-05-22)
To investigate the effects of hypericin which is obtained from the plant Hypericum perforatum on the expression and the regulation of ADAMTS8 and ADAMTS9 genes in MCF7 breast cancer cells and on the viability of these cells. MCF7 cells were
Diana Búzová et al.
General physiology and biophysics, 32(2), 201-208 (2013-03-13)
Hypericin (Hyp) is a promising photosensitizer for photodiagnostic and photodynamic therapy of cancer. However, Hyp has a large conjugated system and in aqueous solutions forms insoluble aggregates which do not possess biological activity. This makes intravenous injection of Hyp problematic
Chen Li et al.
Advanced materials (Deerfield Beach, Fla.), 24(5), 613-636 (2012-01-10)
Perylene imides have been an object of research for 100 years and their derivatives are key n-type semiconductors in the field of organic electronics. While perylene diimides have been applied in many electronic and photonic devices, their use can be
I A Fedorov et al.
The Journal of chemical physics, 138(9), 094509-094509 (2013-03-15)
The electronic structure of crystalline perylene has been investigated within the framework of density functional theory including van der Waals interactions. The computations of the lattice parameters and cohesive energy have good agreement with experimental values. We have also calculated
Sarah M Mickley Conron et al.
The journal of physical chemistry. B, 117(7), 2195-2204 (2013-01-31)
Two X-shaped, cruciform electron donor(2)-acceptor-acceptor'(2) (D(2)-A-A'(2)) molecules, 1 and 2, in which D = zinc 5-phenyl-10,15,20-tripentylporphyrin (ZnTPnP) or zinc 5,10,15,20-tetraphenylporphyrin (ZnTPP), respectively, A = pyromellitimide (PI), and A' = perylene-3,4:9,10-bis(dicarboximide) (PDI), were prepared to study self-assembly motifs that promote photoinitiated
Daniel Görl et al.
Angewandte Chemie (International ed. in English), 51(26), 6328-6348 (2012-05-11)
Perylene bisimides are among the most valuable functional dyes and have numerous potential applications. As a result of their chemical robustness, photostability, and outstanding optical and electronic properties, these dyes have been applied as pigments, fluorescence sensors, and n-semiconductors in
1/2