497-38-1

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Cloning and characterization of the full-length cDNA and genomic sequences encoding murine acid ceramidase.

C M Li et al.

Genomics, 50(2), 267-274 (1998-07-08)

The full-length cDNA and genomic sequences encoding murine acid ceramidase (AC; E.C. 3.5.1.23) have been isolated and characterized. The 2176-bp cDNA was approximately 80% identical to the human cDNA (Koch et al., 1996) and predicted a 394-amino-acid polypeptide that was

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.

Inês Falcão-Pires et al.

American journal of physiology. Heart and circulatory physiology, 296(6), H2007-H2014 (2009-04-07)

We investigated the endogenous production of apelin and the cardiac and pulmonary effects of its chronic administration in monocrotaline (MCT)-induced pulmonary hypertension (PH). Male Wistar rats were injected with MCT (60 mg/kg sc) or vehicle (day 0). One week later

Mouse cytochrome P-450EF, representative of a new 1B subfamily of cytochrome P-450s. Cloning, sequence determination, and tissue expression.

U Savas et al.

The Journal of biological chemistry, 269(21), 14905-14911 (1994-05-27)

A novel benz[a]anthracene and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible cytochrome P-450 (P450EF), which is very active in polycyclic aromatic hydrocarbon metabolism, has been purified from C3H10T1/2 mouse embryo fibroblasts (Pottenger, L. H., Christou, M., and Jefcoate, C. R. (1991) Arch. Biochem. Biophys. 286

Safety profile of modafinil across a range of prescribing indications, including off-label use, in a primary care setting in England: results of a modified prescription-event monitoring study.

Miranda Davies et al.

Drug safety, 36(4), 237-246 (2013-03-14)

Modafinil (Provigil) was marketed in the UK in 1998 to promote wakefulness in the treatment of narcolepsy. In April 2004, the licence was extended to include chronic pathological conditions; 2 years later, the prescription of modafinil was restricted to patients with

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