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Micheline Grignon-Dubois et al.
Phytochemistry, 174, 112312-112312 (2020-03-21)
The invasive species Spartina anglica arose in Europe by a cross between the Afro-European species S. maritima (native, paternal ancestor) and the introduced North American S. alterniflora (invasive, maternal ancestor). Aqueous methanolic extracts were prepared from plant tissue for chemotaxonomical
B Stix et al.
The American journal of pathology, 159(2), 561-570 (2001-08-04)
We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either processing the precursor protein, or by degrading the amyloid deposits. Here
Mark R Kelley et al.
Antioxidants & redox signaling, 14(8), 1387-1401 (2010-09-30)
APE1 is a multifunctional protein possessing DNA repair and redox activation of transcription factors. Blocking these functions leads to apoptosis, antiangiogenesis, cell-growth inhibition, and other effects, depending on which function is blocked. Because a selective inhibitor of the APE redox
Shao-qiu Zheng et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 39(4), 240-244 (2010-07-27)
To study the expression of matrix metalloproteinase (MMP)-2, MMP-9 and vascular endothelial growth factor (VEGF)-C in breast cancer and their role in lymph node metastasis. Immunohistochemical staining was used to detect the expression of VEGF-C, MMP-2, MMP-9 and LYVE-1 in
J P Colombo et al.
Biochemical and biophysical research communications, 172(3), 1239-1245 (1990-11-15)
Urea cycle enzymes are subjected to regulation by dietary proteins. We have shown that this is also the case for N-acetylglutamate synthetase (EC 2.3.1.1.) (NAGS). Four different groups (n = 7) of male Wistar rats received either a low protein
Jennifer Dunlap et al.
American journal of clinical pathology, 135(5), 709-719 (2011-04-20)
Myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms are heterogeneous disorders. JAK2 mutation testing and karyotyping are routinely used for diagnosis but have not been incorporated into risk stratification in Philadelphia chromosome-negative myeloproliferative neoplasms. This study correlated cytogenetic abnormalities with disease stage and
S-Y Jun et al.
Histopathology, 43(1), 17-25 (2003-06-26)
To determine the utility of p57kip2 in the diagnosis of hydatidiform mole. p57kip2 protein is a cyclin-dependent kinase inhibitor (CDKI) and is strongly paternally imprinted, being expressed from the maternal allele. It has been hypothesized that complete mole (CHM) with
Xin Liu et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 30(5-6), 242-248 (2009-10-10)
As an important way to inactivate tumor suppressor genes (TSGs) during cancer development, promoter hypermethylation can be used to define novel TSGs and identify biomarkers for cancer diagnosis. SLC19A3 (solute carrier family 19, member 3) was found to be such
Kiyotaka Okuno et al.
Hepato-gastroenterology, 58(110-111), 1598-1602 (2011-11-17)
Postoperative complications associated with gastrointestinal (GI) perforation may lead to a poor prognosis. The goal of the study was to identify factors required for the establishment of appropriate perioperative procedures in such cases. The subjects were 51 patients with GI
Swasti Tiwari et al.
American journal of nephrology, 30(6), 554-562 (2009-10-22)
We determined the effects of age and sex on the blood pressure (BP) response to angiotensin II (Ang II) infusion and evaluated the potential mechanistic role of the thiazide-sensitive NaCl cotransporter (NCC) and the epithelial sodium channel (ENaC). Male and
Monice M Fiume et al.
International journal of toxicology, 31(5 Suppl), 245S-260S (2012-10-25)
Propylene glycol is an aliphatic alcohol that functions as a skin conditioning agent, viscosity decreasing agent, solvent, and fragrance ingredient in cosmetics. Tripropylene glycol functions as a humectant, antioxidant, and emulsion stabilizer. Polypropylene glycols (PPGs), including PPG-3, PPG-7, PPG-9, PPG-12
Mariko Matsumoto et al.
Reproductive toxicology (Elmsford, N.Y.), 26(3-4), 185-190 (2008-10-18)
The present review paper summarizes the data available in the literature concerning dinitrophenolic compounds and evaluates male reproductive toxicity in experimental animals. Gavage and feeding doses of 2-sec-butyl-4,6-dinitrophenol (dinoseb; CAS No. 88-85-7) manifested testicular toxicity, and 4,6-dinitro-o-cresol (DNOC; CAS No.
Jiang Lin et al.
PloS one, 6(10), e26906-e26906 (2011-11-09)
Somatic mutations of DNMT3A gene have recently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We examined the entire coding sequences of DNMT3A gene by high-resolution melting analysis and sequencing in Chinese patients with myeloid malignancies. R882
S Koling et al.
International journal of clinical pharmacology and therapeutics, 45(9), 496-503 (2007-10-03)
Paracetamol (PCM) is frequently used in pediatric patients with neoplastic disease. It is metabolized mainly by conjugation, but at therapeutic concentrations, a small fraction of the drug undergoes oxidative metabolism via cytochrome P450 forming the hepatotoxic intermediate N-acetyl-p-benzo-quinone-imine (NAPQI) which
Nabil Karah et al.
Annals of clinical microbiology and antimicrobials, 19(1), 2-2 (2020-01-17)
Acinetobacter baumannii is a Gram-negative opportunistic pathogen with a notorious reputation of being resistant to antimicrobial agents. The capability of A. baumannii to persist and disseminate between healthcare settings has raised a major concern worldwide. Our study investigated the antibiotic
Guro E Lind et al.
Cellular oncology : the official journal of the International Society for Cellular Oncology, 28(5-6), 259-272 (2006-12-15)
Gene silencing through CpG island hypermethylation is a major mechanism in cancer development. In the present study, we aimed to identify and validate novel target genes inactivated through promoter hypermethylation in colorectal tumor development. With the use of microarrays, the
Maria S Tretiakova et al.
The American journal of surgical pathology, 28(1), 69-76 (2004-01-07)
Alpha-methylacyl-CoA racemase (AMACR) was first discovered by using cDNA microarray technology as a molecular marker for prostate cancer. Our recent microarray analysis of renal cell carcinomas showed a significant increase of AMACR mRNA levels in papillary renal cell carcinomas, but
Meltem Isikgoz Tasbakan et al.
International journal of antimicrobial agents, 40(6), 554-556 (2012-10-16)
The aim of this study was to evaluate the effect of nitrofurantoin (NFT) in the treatment of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli-related lower urinary tract infection (LUTI). The hospital records of all patients aged >18 years with dysuria or problems
K Sayama et al.
Laboratory animals, 28(1), 44-49 (1994-01-01)
Mammary tumours developed in 110 (95.7%) of 115 DDD/1-Mtv-2/Mtv-2 (DDD/1-Mtv-2) and 24 (47.1%) of 51 DDD/1fDDD/1-Mtv-2 (DDD/1fMtv-2) force-bred female mice during a one-year period. The mean tumour age +/- SE was 220 +/- 7 and 269 +/- 7 days, respectively.
Mika Narikiyo et al.
Oncology letters, 17(3), 3562-3568 (2019-03-15)
The cancer stroma serves an important role in tumour behaviours, including invasion, metastasis, and response to chemotherapy. The stroma of ovarian carcinoma is sometimes specialized, with luteinisation and/or hyperthecosis, and is designated as the 'functioning stroma' because it exerts endocrine
Jerzy Kaleczyc et al.
Journal of anatomy, 239(3), 720-731 (2021-05-11)
The present study investigated the influence of castration performed at neonatal age on neuronal elements in the intramural ganglia of the urinary bladder trigone (UBT) in male pigs using double-labeling immunohistochemistry. The ganglia were examined in intact (IP) 7-day-old (castration
Anja Valen et al.
Drug testing and analysis, 9(5), 808-823 (2016-07-29)
Collection of oral fluid (OF) is easy and non-invasive compared to the collection of urine and blood, and interest in OF for drug screening and diagnostic purposes is increasing. A high-throughput ultra-high-performance liquid chromatography-tandem mass spectrometry method for determination of
M Hersom et al.
Journal of animal science, 93(6), 3169-3178 (2015-06-27)
Our objective was to evaluate the response of weaned calves to different supplemental feed additives in a supplement to affect calf performance and mitigate stress response observed during weaning and preconditioning. At weaning in each of 2 yr, 160 Angus
Ruth M Escalona et al.
Molecular and cellular endocrinology, 307(1-2), 149-156 (2009-06-16)
Betaglycan is an inhibin-binding protein co-receptor, the forced expression of which confers inhibin responsiveness on cells previously non-responsive to inhibin. The present study determines whether removal of betaglycan expression in otherwise inhibin-responsive cells will render the cells insensitive to inhibin.
Ratna K Vadlamudi et al.
Human pathology, 36(6), 670-675 (2005-07-16)
Salivary duct carcinoma (SDC) is a high-grade neoplasm with marked morphological resemblance to mammary duct carcinoma. The novel estrogen receptor (ER)-interacting protein and the proline-, glutamic acid-, and leucine-rich protein 1 ( PELP1 ), also called the modulator of nongenomic
Andrew M Jenner et al.
Free radical biology & medicine, 38(6), 763-772 (2005-02-22)
Phenolic compounds are not completely absorbed in the small intestine and so enter the colon, where they might exert physiological effects. To identify phenolics that are present in normal human colon, fecal water was prepared from 5 free-living volunteers with
Sayaka Yamazaki et al.
Japanese journal of infectious diseases, 69(5), 367-372 (2016-01-09)
Because western blotting occasionally causes cross-reactions between human immunodeficiency virus (HIV)-1 and HIV-2, it is difficult to distinguish a coinfection status from a false-positive result. Therefore, we developed a qualitative real-time PCR assay to detect HIV-1 and HIV-2 RNA that
A new preservation solution for lung transplantation: evaluation in a porcine transplantation model.
Nikolaus Pizanis et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31(3), 310-317 (2012-01-10)
Lung preservation injury is still a major problem in lung transplantation. The aim of the current study was to evaluate the effects of a new preservation solution (Custodiol-N) for lung preservation. Using an in vivo pig model, 7 lungs each
A Räisänen-Sokolowski et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 18(8), 735-743 (1999-10-08)
Mice with target gene deletions were used in an immunosuppressed, heterotopic mouse cardiac transplant model to investigate the effects of simultaneous deficiencies of ICAM-1 and P-selectin on late cardiac rejection. To determine the contribution of donor sources of ICAM-1 and
Jung-Eun Yang et al.
International journal of systematic and evolutionary microbiology, 63(Pt 12), 4396-4401 (2013-07-09)
A Gram-reaction-negative, strictly aerobic, non-motile, non-spore-forming and rod-shaped bacterial strain, designated THG-45(T), was isolated from soil of a ginseng field of Pocheon province in the Republic of Korea and its taxonomic position was investigated by a polyphasic approach. Growth occurred
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