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显示 1-30 共 61 条结果 关于 "53-19-0" 范围 论文
Leonel Maldonado et al.
Oncotarget, 5(14), 5218-5233 (2014-07-02)
By a candidate gene approach, we analyzed the promoter methylation (PM) of 8 genes genes (ARF, TIMP3, RAR-β2, NID2, CCNA1, AIM1, CALCA and CCND2) by quantitative methylation specific PCR (QMSP) in DNA of 17 non-recurrent and 19 recurrent noninvasive low
Charles J Glueck et al.
The American journal of cardiology, 105(6), 792-796 (2010-03-10)
Because the endothelial nitric oxide synthase (eNOS) T-786C polymorphism is associated with reduced nitric oxide production and coronary artery spasm in Japanese patients, we speculated that it might be reversibly associated with Prinzmetal's variant angina in white Americans. Polymerase chain
Oswaldo Castro et al.
British journal of haematology, 167(5), 687-691 (2014-08-26)
Using health insurance claims databases we compared the frequency/incidence of acute myeloid leukaemia (AML) and inpatient mortality in sickle cell disease (SCD) subjects taking (n = 1051), or not taking (n = 9203) hydroxycarbamide (HC). Patients taking HC were older (median 19 vs. 17 years
J Sun et al.
British poultry science, 53(3), 374-378 (2012-09-18)
1. A pharmacokinetic study of valnemulin was conducted in healthy Muscovy ducks after intravenous (IV), intramuscular (IM) and oral administrations at a dose rate of 15 mg/kg body weight. 2. Drug concentrations in plasma were determined by high performance liquid
Ananth Shankar et al.
British journal of haematology, 165(4), 534-544 (2014-04-24)
The purpose of this national retrospective study was to evaluate the outcome in children with relapsed or primary refractory Hodgkin lymphoma [HL] after a primary chemotherapy alone treatment strategy. Between 2000 and 2005, 80 children with relapsed [n = 69]
Hong Zhang et al.
PloS one, 10(7), e0132509-e0132509 (2015-07-15)
Seed vigor is a complex property that determines the seed's potential for rapid uniform emergence and subsequent growth. However, the mechanism for change in seed vigor is poorly understood. The seeds of poplar (Populus × Canadensis Moench), which are short-lived
Matthew A Cavender et al.
Lancet (London, England), 384(9943), 599-606 (2014-08-19)
Bivalirudin is an alternative to heparin in patients undergoing percutaneous coronary intervention (PCI). We aimed to define the effects of a bivalirudin-based anticoagulation regimen compared with a heparin-based anticoagulation regimen on ischaemic and bleeding outcomes. We searched Medline, the Cochrane
T Han et al.
Letters in applied microbiology, 57(4), 336-343 (2013-06-25)
In this report, a glycoside hydrolase 13 family pullulanase gene (Tk0977) was cloned from a thermophilic anaerobic archaeon Thermococcus kodakarensis KOD1 (Pul-Tk). Pul-Tk encodes a protein of 765 amino acids including a putative 22-residue signal peptide. The protein has four
Jose M Rubio et al.
The lancet. Psychiatry, 7(9), 749-761 (2020-08-24)
Most individuals with schizophrenia-spectrum disorders have relapses, which increase the risk of morbidity and mortality. Because non-adherence to antipsychotic maintenance treatment could affect more than half of individuals with schizophrenia-spectrum disorders, psychosis relapse can often be confounded by unnoticed treatment
H B Feys et al.
Vox sanguinis (2018-05-26)
A disposable set for platelet concentrate (PC) preparation by the buffy coat method allows pooling of buffy coats, centrifugation and cell separation with in-line leucocyte filtration. This study compares three commercially available pooling sets in combination with INTERCEPT pathogen inactivation
Yoshihiro Ohishi et al.
Histopathology, 58(3), 423-432 (2011-02-09)
The role of misregulated Wnt/beta-catenin signalling in human ovarian granulosa cell tumour (GCT) has not been well characterized. The aim of this study was to confirm subcellular localization of key molecules of Wnt signalling (beta-catenin and E-cadherin) in human ovarian
Naoyuki Umetani et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 10(22), 7475-7483 (2004-12-01)
ID4 gene is a member of the inhibitor of DNA binding (ID) family proteins that inhibit DNA binding of basic helix-loop-helix transcription factors. The epigenetic inactivation of ID4 gene on colorectal cancer (CRC) development and its clinical significance was assessed.
Roy F Chemaly et al.
Journal of pediatric hematology/oncology, 36(6), e376-e381 (2013-12-12)
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections (LRTIs) in children, especially those with cancer. Data on RSV infections in this vulnerable population is limited. We conducted a retrospective study of all RSV infections in
Huiwen Jiang et al.
Annals of hematology, 98(7), 1721-1732 (2019-05-06)
The CD19-targeted chimeric antigen receptor T cell (CAR-T) therapy has been widely proved effective on relapsed and refractory (r/r) B cell acute lymphoblastic leukemia (B-ALL). Meanwhile, CAR-T therapy-related toxicities, including cytokine release syndrome (CRS) and neurological toxicities, are drawing researchers'
Geltrude Mingrone et al.
Lancet (London, England), 386(9997), 964-973 (2015-09-16)
Randomised controlled trials have shown that bariatric surgery is more effective than conventional treatment for the short-term control of type-2 diabetes. However, published studies are characterised by a relatively short follow-up. We aimed to assess 5 year outcomes from our
Gordon Cook et al.
The Lancet. Oncology, 15(8), 874-885 (2014-06-21)
Relapsed multiple myeloma has no standard treatment, and the role of autologous stem-cell transplantation (ASCT) has not been fully defined. We aimed to compare high-dose melphalan plus salvage ASCT with cyclophosphamide in patients with relapsed multiple myeloma who had previously
P Opfermann et al.
Clinical and experimental immunology, 180(1), 131-142 (2014-11-18)
Reparixin, a CXCR 1/2 antagonist, has been shown to mitigate ischaemia-reperfusion injury (IRI) in various organ systems in animals, but data in humans are scarce. The aim of this double-blinded, placebo-controlled pilot study was to evaluate the safety and efficacy
Xing-Ming Li et al.
Journal of clinical nursing, 26(3-4), 369-378 (2016-09-21)
Our study was conducted to further investigate the model of social support and care for People Living with HIV/AIDS(PLHA), to explore their role in People Living with AIDS's quality of life (QOL) as reference for improving nursing policies for AIDS.
Kiyotaka Yoh et al.
Lung cancer (Amsterdam, Netherlands), 62(3), 316-320 (2008-05-02)
This study was conducted to evaluate the prevalence of EGFR and KIT mutations in thymomas and thymic carcinomas as a means of exploring the potential for molecularly targeted therapy with tyrosine kinase inhibitors. Genomic DNA was isolated from 41 paraffin-embedded
Brian T Steffen et al.
The British journal of nutrition, 110(9), 1664-1671 (2013-04-05)
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an independent risk factor for CVD and has been proposed as a marker of vascular inflammation. Polyunsaturated n-3 fatty acids (FA) and several n-6 FA are known to suppress inflammation and may influence Lp-PLA2 mass
Michelle D Williams et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 16(8), 2266-2274 (2010-04-08)
Salivary duct carcinoma overexpresses epidermal growth factor receptor (EGFR) and HER-2, although the underlying mechanisms remain undefined. Because of the potential utilization of these markers as treatment targets, we evaluated protein and gene status by several techniques to determine complementary
Matthew H Kulke et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(1), 338-345 (2009-01-02)
Recent studies suggest that temozolomide has activity in neuroendocrine tumors. Low levels of the DNA repair enzyme, O(6)-methylguanine DNA methyltransferase (MGMT), are associated with sensitivity to temozolomide in other tumor types. We evaluated the prevalence of MGMT deficiency in neuroendocrine
Frederick J Raal et al.
Lancet (London, England), 385(9965), 331-340 (2014-10-06)
Heterozygous familial hypercholesterolaemia is characterised by low cellular uptake of LDL cholesterol, increased plasma LDL cholesterol concentrations, and premature cardiovascular disease. Despite intensive statin therapy, with or without ezetimibe, many patients are unable to achieve recommended target levels of LDL
Matteo Cescon et al.
Journal of hepatology, 50(5), 937-947 (2009-03-24)
The efficacy of ischemic preconditioning (IPC) in preventing reperfusion injury in human liver transplants is still questioned. Phosphoinositide-3-kinase (PI3K) is essential for IPC development in rodent livers. This work investigates whether PI3K-dependent signals might account for the inconsistent responses to
Priscilla M K Poon et al.
Clinical biochemistry, 39(3), 244-248 (2005-12-13)
To study the AGG interspersion pattern in mentally retarded patients of unspecified cause. FMR1 CGG substructure in 104 normal and 232 mentally retarded (MR) males was determined by CGG repeat and AGG interspersion analyses. Genomic DNA of the study subjects
John Frater et al.
The lancet. HIV, 8(8), e474-e485 (2021-06-22)
Data on vaccine immunogenicity against SARS-CoV-2 are needed for the 40 million people globally living with HIV who might have less functional immunity and more associated comorbidities than the general population. We aimed to explore safety and immunogenicity of the
Minna K Kankuri-Tammilehto et al.
Anticancer research, 30(7), 3023-3030 (2010-08-05)
Prognosis of renal cell carcinoma (RCC) differs within the same stage and grade. Our aim was to investigate the incidence of COX-2 in primary RCC tumors at different stages according to the occurrence of metastasis, and the impact of this
J Kaur et al.
European journal of cancer. Part B, Oral oncology, 32B(1), 45-49 (1996-01-01)
We have previously shown overexpression of p53 and 70 kDa heat shock protein (HSP70) in potentially malignant, as well as malignant, oral lesions in an Indian population, suggesting that alterations of p53 and HSP70 expression may occur in the early
S Beussel et al.
Journal of clinical pathology, 65(1), 29-35 (2011-10-21)
Aurora kinases are central to cell proliferation and considered to be prognostic/predictive markers and therapeutic targets for epithelial cancers. Here, the prognostic/predictive value of Aurora-B protein expression was evaluated in patients with serous, FIGO stage III ovarian carcinomas treated with
Sanjay Kakar et al.
Archives of pathology & laboratory medicine, 132(6), 958-964 (2008-06-04)
The 2 chief pathways implicated in colorectal carcinogenesis, microsatellite instability and chromosomal instability, are not present in 20% to 37% of cases. To determine whether the CpG island methylator phenotype (CIMP) pathway, characterized by simultaneous methylation of several known tumor
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