538-74-9

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Molecular determinants of inactivation within the I-II linker of alpha1E (CaV2.3) calcium channels.

L Berrou et al.

Biophysical journal, 80(1), 215-228 (2001-02-13)

Voltage-dependent inactivation of CaV2.3 channels was investigated using point mutations in the beta-subunit-binding site (AID) of the I-II linker. The quintuple mutant alpha1E N381K + R384L + A385D + D388T + K389Q (NRADK-KLDTQ) inactivated like the wild-type alpha1E. In contrast

Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation.

Conor L Mallucci et al.

Lancet (London, England), 394(10208), 1530-1539 (2019-09-17)

Insertion of a ventriculoperitoneal shunt for hydrocephalus is one of the commonest neurosurgical procedures worldwide. Infection of the implanted shunt affects up to 15% of these patients, resulting in prolonged hospital treatment, multiple surgeries, and reduced cognition and quality of

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