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显示 1-30 共 582 条结果 关于 "57-10-3" 范围 论文
K A Alexander et al.
The Journal of biological chemistry, 262(13), 6108-6113 (1987-05-05)
P-57 is a neural-specific calmodulin binding protein with novel calmodulin binding properties. P-57 exhibits higher affinity for calmodulin-Sepharose in the absence of free Ca2+ than in the presence of Ca2+ (Andreasen, T.J., Luetje, C.W., Heideman, W. & Storm, D.R. (1983)
F H Arthur
Journal of economic entomology, 94(3), 772-779 (2001-06-27)
Last instar larvae of the red flour beetle, Tribolium castaneum (Herbst), and the confused flour beetle, Tribolium confusum Jacquelin du Val, were either exposed for 8-144 h on concrete treated with 1.9 x 10(-3) mg(AI)/per cm2 hydroprene, or continually exposed
Michael T Henzl et al.
Biochemistry, 46(1), 23-35 (2007-01-03)
Although rat beta-parvalbumin and chicken parvalbumin 3 (CPV3) are identical at 74 of 108 residues, rat beta exhibits perceptibly lower Ca2+ and Mg2+ affinities. At 25 degrees C, in Hepes-buffered saline, at pH 7.4, the overall deltadeltaG degrees ' values
Mitsuhiko Ohta et al.
Oncology reports, 15(6), 1529-1532 (2006-05-11)
We previously reported some cancer testis antigens, especially for MAGE genes, to be expressed in a relatively high population of gastro-intestinal and breast cancers. TRAG-3 (Taxol resistant associated gene-3) may be another cancer testis antigen; however, its expression has still
Ping Ye et al.
Endocrinology, 144(8), 3321-3328 (2003-07-17)
We have developed a highly sensitive QRT-PCR method for the measurement of CYP11B1 (11beta-hydroxylase) and CYP11B2 (aldosterone synthase) mRNAs to study their expression in the rat brain in response to dietary sodium manipulation and angiotensin (Ang)II infusion. Male Wistar Kyoto
Younis Baqi et al.
Journal of medicinal chemistry, 54(3), 817-830 (2011-01-07)
Evaluation and optimization of anthraquinone derivatives related to Reactive Blue 2 at P2X2 receptors yielded the first potent and selective P2X2 receptor antagonists. The compounds were tested for inhibition of ATP (10 μM) mediated currents in Xenopus oocytes expressing the
D G Birch et al.
Investigative ophthalmology & visual science, 33(8), 2365-2376 (1992-07-01)
Full-field electroretinograms (ERGs) were obtained from very-low-birth-weight (VLBW) neonates to determine whether omega-3 (omega-3) fatty acids are essential for normal human retinal development. Eighty-one infants born at 30.4 (standard deviation, +/- 1.5) wk gestation were, within 10 d of birth
F Arnal et al.
Neurochemical research, 15(6), 587-591 (1990-06-01)
We have synthesized the tertiary amines of pyridostigmine and neostigmine, 3-pyridinol dimethylcarbamate (norpyridostigmine) and 3-dimethylaminophenol dimethylcarbamate (norneostigmine) respectively, and we have tested their abilities to cross the blood-brain barrier and inhibit mouse brain AChE activity. The in vivo inhibition of
H R Lijnen et al.
Thrombosis and haemostasis, 87(3), 530-535 (2002-03-28)
Several matrix metalloproteinases (MMPs), including the stromelysins MMP-3 and MMP-11, are expressed in adipose tissue. To investigate a potential role of MMP-11 (stromelysin-3) in adipose tissue development, five-week-old male wild-type mice (MMP-11+/+) or mice with deficiency of MMP-11 (MMP-11-/-) were
Yoshihiko Kitajima et al.
Oncology reports, 19(1), 197-202 (2007-12-22)
Runx3, a member of the human runt-related transcription factor family, is known as a possible tumor suppressor gene for gastric cancer. Runx 3 expression is frequently suppressed by the promoter hypermethylation in gastric cancer cell lines and tissues. However, the
Ayşe Demirkan et al.
PLoS genetics, 8(2), e1002490-e1002490 (2012-02-24)
Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are required for active transport, a number of enzymatic processes, membrane formation, and cell signalling. Disruption of their metabolism leads to several diseases, with diverse neurological, psychiatric, and metabolic
Kay Ka Wai Li et al.
International journal of cancer, 120(4), 947-950 (2006-12-26)
The epithelial membrane protein 3 (EMP3) gene located on chromosome 19q13 has been implicated as a candidate tumor suppressor gene (TSG) in neuroblastomas and gliomas. The aim of this study was to investigate whether EMP3 is involved in oligodendroglial tumors
Yuan Yuan et al.
Diagnostic cytopathology, 39(8), 562-566 (2010-08-24)
We recently identified overexpression of the NTN4 gene in breast carcinoma effusions compared to primary carcinomas using gene-expression arrays. The objective of this study was to validate this finding at protein level and analyze the clinical role of Netrin-4 in
Ken-ichi Fujita et al.
Cancer chemotherapy and pharmacology, 60(4), 515-522 (2007-04-05)
The phenotypic effects of UGT1A7 and UGT1A9 genetic polymorphisms on the in vivo pharmacokinetics of irinotecan were examined. Eighty-four Japanese patients with cancer who received irinotecan-based chemotherapy were enrolled. Polymorphisms present in UGT1A7 (T to G transversion at -57 and
J Robbins et al.
Journal of virology, 66(4), 2594-2599 (1992-04-01)
Expression of a 2.3-kb RNA species is induced in mammary tumors as a consequence of insertional mutagenesis at the int-3 locus by the mouse mammary tumor virus. The nucleotide sequence and biological activity of this mammary tumor-specific int-3 RNA species
Omar Barakat et al.
Journal of surgical oncology, 102(7), 816-820 (2010-09-03)
Previous studies suggest that serum hepatocyte growth factor (HGF) level may be a useful diagnostic and prognostic biomarker for various tumors. We investigated the utility of plasma HGF level measurements in diagnosing periampullary cancer (PAC). Of the patients enrolled in
L He et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 28(5), 337-339 (2002-03-01)
To investigate the clinicopathological, immunohistochemical features and the histogenesis of pancreatoblastoma (PB) in 14 pediatric cases, including 9 male and 5 female patients, their age ranged from 1.5 to 8 years with a mean of 4.4 years. Routine pathological, histochemical
Paul J McLaren et al.
Human molecular genetics, 21(19), 4334-4347 (2012-06-22)
A small proportion of human immunodeficiency virus-1 (HIV-1) infected individuals, termed HIV-1 controllers, suppress viral replication to very low levels in the absence of therapy. Genetic investigations of this phenotype have strongly implicated variation in the class I major histocompatibility
J Taylor et al.
Pflugers Archiv : European journal of physiology, 442(2), 256-262 (2001-06-22)
We used the Ussing short-circuit technique to investigate the role of HCO3- in the adenosine 3',5'-cyclic monophosphate (cAMP)-dependent secretory response of the human distal colon. In HCO3(-)-free 4-(2-hydroxyethyl)-1-piperazineethanesulphonic acid (HEPES)-Ringer's, forskolin (10 mumol l-1 mucosal and serosal) evoked a sustained
N Kawasaki et al.
Chemical & pharmaceutical bulletin, 47(2), 177-181 (1999-03-11)
A novel series of trimethylhydroquinone derivatives was synthesized and evaluated for their anti-lipid peroxidation activity in rat liver microsomes, inhibition of rat basophilic leukemia-1 (RBL-1) cell 5-lipoxygenase and 48 h homologous passive cutaneous anaphylaxis (PCA) activity in rats. 4-[4-[4-(Diphenylmethyl)-1-piperazinyl]-butoxy]-2,3,6-trimethyl phenol
Minae Kawashima et al.
Sleep, 33(7), 869-874 (2010-07-10)
Recent studies have found increased autoantibodies against Tribbles homolog 2 (anti-TRIB2) and anti-streptolysin O (ASO) in narcolepsy. In this study, we replicated this finding with a primary focus on recent onset cases. Participants included (1) 90 cases with cataplexy, (2)
Hideo Utsumi et al.
Water research, 37(20), 4924-4928 (2003-11-08)
Hydroxyl (OH) radical is proposed as an important factor in the ozonation of water. In the present study, the enhancing effect of 3-chlorophenol on OH radical generation was mathematically evaluated using electron spin resonance (ESR)/spin-trapping technique. OH radical was trapped
Rachit Agarwal et al.
Biomaterials, 63, 137-145 (2015-06-24)
Metal implants are widely used to provide structural support and stability in current surgical treatments for bone fractures, spinal fusions, and joint arthroplasties as well as craniofacial and dental applications. Early implant-bone mechanical fixation is an important requirement for the
A Welz et al.
Journal of cardiac surgery, 7(2), 163-169 (1992-06-01)
A canine femoral artery model was used for evaluation of a dialdehyde starch preserved bovine internal mammary artery (BIMA) (3 and 4 mm internal diameter) in comparison to a polytetrafluoroethylene (PTFE) graft. The study comprised three groups for a 2-hour
Oya Topaloglu et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 21(5), 428-433 (2013-11-10)
The aim of this study was to evaluate the relationship between vitamin D levels and hemostatic factors like tissue factor pathway inhibitor (TFPI). Patients who had 25-hydroxyvitamin D3 (25(OH)D3) levels measured were included. Coagulation and hemostatic parameters were evaluated. Patients
T J Knott et al.
Nucleic acids research, 12(9), 3909-3915 (1984-05-11)
cDNA clones encoding human apolipoprotein CI have been isolated from an adult liver cDNA library. Apo CI mRNA was shown to have two species of approximately 580 and 560 bases by RNA blot hybridisation. The intracellular precursor of apo CI
Jinxu Zhou et al.
Journal of neuro-oncology, 110(2), 195-203 (2012-09-14)
Golgi phosphoprotein-3 (GOLPH3), an important protein in mammalian target of rapamycin (mTOR) signaling, is overexpressed in and correlates with the pathological grade of glioma. However, the potential correlation between GOLPH3 and clinical outcome in patients with glioblastoma multiforme (GBM) remains
Milica Keckarevic-Markovic et al.
Journal of the peripheral nervous system : JPNS, 14(2), 125-136 (2009-08-21)
We report the results of mutational analysis in the following genes: GJB1, MPZ, PMP22, EGR2, and LITAF/SIMPLE in 57 Charcot-Marie-Tooth (CMT) patients of Serbian origin without the PMP22 duplication. We found 10 different mutations in 14 CMT patients: 6 mutations
O B Loran et al.
Urologiia (Moscow, Russia : 1999), (4), 16-19 (2005-09-15)
We studied the role of integrins, primarily, the role of allele distribution of GP3a gene in development of prostatic cancer (PC) and assessment of its prognostic significance. From November 2003 to May 2004 we examined 32 patients with PC: 11
P Poorkaj et al.
Archives of neurology, 58(3), 383-387 (2001-03-20)
Mutations in the tau gene have been reported in families with frontotemporal dementia (FTD) linked to chromosome 17. It remains uncertain how commonly such mutations are found in patients with FTD or non-Alzheimer dementia with or without a positive family
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