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Chao Li et al.
Environmental pollution (Barking, Essex : 1987), 196, 47-52 (2014-10-10)
Physiologically based in vitro methods have been developed to measure bioaccessibility of organic contaminants in soils. However, bioaccessibility of hydrophobic organic contaminants (HOCs) can be underestimated by in vitro tests if gastrointestinal (GI) solution fails to provide sufficient sorption sink
Qiliang Lai et al.
Journal of bacteriology, 194(24), 6956-6956 (2012-12-05)
Thalassospira profundimaris WP0211(T) was isolated from a pyrene-degrading consortium, enriched from deep-sea sediment collected from the West Pacific Ocean. Here, we present the draft genome of strain WP0211(T), which contains 4,380,232 bp with a G+C content of 55.19% and contains
Aurelio Mateo-Alonso et al.
Organic letters, 15(1), 84-87 (2012-12-22)
A solvent switchable rotaxane equipped with a pyrene stopper and with two ferrocenyl units on the macrocycle is reported, in which three different states, two nondegenerate and one degenerate, can be obtained in different solvents at room temperature. This is
Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR.
Xiao-Jie Zhang et al.
Toxicological sciences : an official journal of the Society of Toxicology, 147(2), 436-445 (2015-07-15)
Polycyclic aromatic hydrocarbons (PAHs) are a class of ubiquitous persistent environmental pollutants which are primarily formed from the incomplete combustion of organic materials. Many potential sources of human exposure to PAHs exist, including daily exposures from the ambient environment or
Marta Fontal et al.
Journal of chromatography. A, 1404, 28-38 (2015-06-10)
A method for the quantitative analysis of organic compounds on submicron particulate matter (PM1) collected on quartz filters was developed. The compounds analyzed encompassed C22-C35 alkanes, polycyclic aromatic hydrocarbons (PAHs), quinones, levoglucosan, cis-pinonic acid and short chain dicarboxylic acids such
Yong-Hui Wang et al.
Food & function, 6(8), 2636-2645 (2015-07-03)
In this paper, we developed amphiphilic zein hydrolysate (ZH) as a novel delivery vehicle, which could be used for preparing curcumin (Cur) nanocomplexes. These ZH-Cur nanocomplexes exhibited spherical morphology with a monodisperse size distribution (<50 nm), and the dispersion was
Markus Brinkmann et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 38-46 (2014-04-15)
As a consequence of global climate change, we will be likely facing an increasing frequency and intensity of flood events. Thus, the ecotoxicological relevance of sediment re-suspension is of growing concern. It is vital to understand contaminant uptake from suspended
Qi Zhang et al.
Archives of environmental contamination and toxicology, 69(2), 133-142 (2015-04-04)
In this study, ice and water samples were collected from seven sites along the Baotou section of the Yellow River during winter 2013. Total polycyclic aromatic hydrocarbon (PAH) concentrations in the ice and in the water under the ice ranged
Yehua Han et al.
Journal of chromatography. A, 1395, 1-6 (2015-04-18)
A supercritical fluid extraction (SFE) method with an online solid collection trap has been developed for the quantitative analysis of 16 polycyclic aromatic hydrocarbons (PAHs) and 15 typical PAH derivatives in solid matrix. Compared with liquid trapping and C18 solid-phase
Bo-hyun Choi et al.
PloS one, 9(9), e107158-e107158 (2014-09-17)
Photodynamic therapy (PDT) has emerged as an effective treatment for various solid tumors. The transcription factor NRF2 is known to protect against oxidative and electrophilic stress; however, its constitutive activity in cancer confers resistance to anti-cancer drugs. In the present
Miroslava Dékány Fraňová et al.
Biochimica et biophysica acta, 1838(5), 1406-1411 (2014-02-11)
The lateral pressure profile of lipid bilayers has gained a lot of attention, since changes in the pressure profile have been suggested to shift the membrane protein conformational equilibrium. This relation has been mostly studied with theoretical methods, especially with
Luís M S Loura et al.
Biochimica et biophysica acta, 1828(3), 1094-1101 (2013-01-01)
Molecular dynamics (MD) simulations of bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) with varying amounts of cholesterol (0, 5, 20, and 40mol%) were carried out in the absence and presence of inserted pyrene molecules. Both fluorophore and bilayer parameters were computed, for characterization
Jingmou Yu et al.
Journal of biomaterials science. Polymer edition, 26(18), 1475-1489 (2015-10-23)
A series of linoleic acid-modified glycol chitosan (LAGC) conjugates were synthesized and characterized by FTIR and (1)H NMR. The effect of the amount of linoleic acid (LA) on the physicochemical properties of LAGC conjugates was investigated. The mean diameters of
Yeimy J Rodriguez et al.
Pharmaceutics, 12(3) (2020-02-29)
Amphotericin B (AmB) is a broad spectrum of antifungal drug used to treat antifungal diseases. However, due to the high toxicity of AmB, treated patients may suffer the risk of side effects, such as renal failure. Nanoencapsulation strategies have been
Hitesh S Purohit et al.
Molecular pharmaceutics, 12(5), 1623-1635 (2015-04-09)
The purpose of this study was to develop a novel fluorescence technique employing environment-sensitive fluorescent probes to study phase separation kinetics in hydrated matrices of amorphous solid dispersions (ASDs) following storage at high humidity and during dissolution. The initial miscibility
Shveta Mahajan et al.
Nanotechnology, 24(1), 015603-015603 (2012-12-12)
Polymer-SPION hybrids were investigated for receptor-mediated localization in tumour tissue. Superparamagnetic iron oxide nanoparticles (SPIONs) prepared by high-temperature decomposition of iron acetylacetonate were monodisperse (9.27 ± 3.37 nm), with high saturation magnetization of 76.8 emu g(-1). Amphiphilic copolymers prepared from
Exploring the speed-resolution limits of supercritical fluid chromatography at ultra-high pressures.
Ruben De Pauw et al.
Journal of chromatography. A, 1374, 247-253 (2014-12-08)
The limits of supercritical fluid chromatography have been experimentally explored using inlet pressures at the limits of the current commercial instrumentation (400-600 bar), as well as pressures significantly surpassing this (up to 1050 bar). It was found that efficiencies in
Abimbola Comfort Badejo et al.
PloS one, 8(2), e58066-e58066 (2013-03-08)
Polycyclic aromatic hydrocarbons (PAHs) are toxic pollutants found in the environment which can be removed through the use of physical and biological agents. The rate of PAH biodegradation is affected by environmental conditions of pH, salinity and temperature. Adaptation of
Thiloka C Ariyasena et al.
Journal of chromatography. A, 1361, 240-254 (2014-08-30)
Retention factors on several columns and at various temperatures using gas chromatography and from reversed-phase liquid chromatography on a SunFire C18 column with various mobile phase compositions containing acetonitrile, methanol and tetrahydrofuran as strength adjusting solvents are combined with liquid-liquid
O O Alabi et al.
Chemical communications (Cambridge, England), 51(33), 7152-7155 (2015-03-27)
Surface enhanced Raman spectroscopy using a gold substrate and excitation at 514 nm can detect sub parts per million quantities of asphaltene and thereby petroleum. This simple format and sensitivity make it transformative for applications including sample triage, flow assurance
Xanel Vecino et al.
Journal of agricultural and food chemistry, 63(32), 7143-7150 (2015-07-25)
A decontamination technique based on the utilization of a lipopeptide biosurfactant extracted from corn steep liquor has been developed to eliminate polycyclic aromatic hydrocarbons (PAHs) from sewage sludge. High concentrations of PAHs were used during experiments observing that 408.3 mg/kg
Yoshinori Ikenaka et al.
Environmental toxicology and pharmacology, 39(3), 1148-1153 (2015-04-29)
Red gourami (Colisa labiosa) have previously been shown to have low levels of pyrene-metabolizing activity. In this study, other pharmacokinetic factors of pyrene in C. labiosa were compared to those in Japanese medaka (Oryzias latipes). Results indicated that the two
Zahra Daman et al.
International journal of pharmaceutics, 468(1-2), 142-151 (2014-04-16)
Although gemcitabine (Gem) constitutes first-line therapy for pancreatic cancer, its clinical outcome suffers from rapid metabolism and acquired drug resistance. To overcome its limitations, several lipophilic prodrugs including 4-(N)-stearoyl Gem (GemC18) have been studied for their efficacy over Gem. Herein
María Navarro-Pascual-Ahuir et al.
Analytical and bioanalytical chemistry, 406(25), 6329-6336 (2014-07-31)
The preparation of polymeric monoliths with embedded carboxy-modified single-walled carbon nanotubes (c-SWNTs) and their use for capillary electrochromatography (CEC) is described. Carbon nanotube composites were obtained by preparing a polymerization mixture in the presence of increasing c-SWNT concentrations, followed by
Gursharan Bains et al.
Molecules (Basel, Switzerland), 16(9), 7909-7935 (2011-12-07)
The review focuses on the unique spectral features of pyrene that can be utilized to investigate protein structure and conformation. Pyrene is a fluorescent probe that can be attached covalently to protein side chains, such as sulfhydryl groups. The spectral
Minming Wu et al.
Materials science & engineering. C, Materials for biological applications, 45, 162-169 (2014-12-11)
Novel biomimetic amphiphilic chitosan derivative, deoxycholic acid-phosphorylcholine-chitosan conjugate (DCA-PCCs) was synthesized based on the combination of Atherton-Todd reaction for coupling phosphorylcholine (PC) and carbodiimide coupling reaction for linking deoxycholic acid (DCA) to chitosan. The chemical structure of DCA-PCCs was characterized
Tomohiro Kato et al.
Journal of the American Chemical Society, 135(2), 741-750 (2012-12-18)
Although distance dependence of Förster resonance energy transfer (FRET) is well-studied and FRET has been extensively applied as "molecular ruler", only limited examples of orientation-dependent FRET have been reported. To create a robust FRET system that precisely reflects the orientation
Chan Yu et al.
Bulletin of environmental contamination and toxicology, 93(5), 632-636 (2014-09-14)
The surrounding environment near Dagang oil-production well suffers polycyclic aromatic hydrocarbons (PAHs) pollution. In the present study, indigenous microorganisms capable of degrading PAHs were isolated and the efficiency of PAHs removal was investigated. Seven PAH-degrading strains were isolated with the
Rulin Cai et al.
Materials science & engineering. C, Materials for biological applications, 33(4), 2070-2077 (2013-03-19)
We report here a novel approach to fabricate a nanostructured micelle as potential drug carriers and the relationship between the morphological structure and the preparation condition. The polymeric micelle aggregates constructed by self-assembly compose of the poly(ε-caprolactone)/monomethoxy poly(ethylene glycol) linear-dendritic
Masahiro Mizuno et al.
Langmuir : the ACS journal of surfaces and colloids, 31(8), 2334-2341 (2015-02-12)
A new microfluidic process was used to generate unique micrometer-sized hierarchical lipid particles having spherical lipid-core and multilamellar-shell structures. The process includes three steps: (1) formation of monodisperse droplets in a nonequilibrium state at a microchannel confluence, using a phospholipid-containing
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