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Hierarchically-structured silver nanoflowers for highly conductive metallic inks with dramatically reduced filler concentration.

Muhammed Ajmal C et al.

Scientific reports, 6, 34894-34894 (2016-10-08)

Silver has long been employed as an electrically conductive component, and morphology-dependent properties have been actively investigated. Here we present a novel scalable synthesis method of flower-shaped silver nanoparticles (silver nanoflowers, Ag NFs). The preferential affinity of citrate molecules on

Polygenic overlap between kidney function and large artery atherosclerotic stroke.

Elizabeth G Holliday et al.

Stroke, 45(12), 3508-3513 (2014-10-30)

Epidemiological studies show strong associations between kidney dysfunction and risk of ischemic stroke (IS), the mechanisms of which are incompletely understood. We investigated whether these associations may reflect shared heritability because of a common polygenic basis and whether this differed

T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.

Benjamin A Raby et al.

American journal of respiratory and critical care medicine, 173(1), 64-70 (2005-09-24)

T-bet (TBX21 or T-box 21) is a critical regulator of T-helper 1 lineage commitment and IFN-gamma production. Knockout mice lacking T-bet develop airway hyperresponsiveness (AHR) to methacholine, peribronchial eosinophilic and lymphocytic inflammation, and increased type III collagen deposition below the

Identification of large gene deletions and duplications in KCNQ1 and KCNH2 in patients with long QT syndrome.

Carey-Anne Eddy et al.

Heart rhythm, 5(9), 1275-1281 (2008-09-09)

Sequencing or denaturing high-performance liquid chromatography (dHPLC) analysis of the known genes associated with the long QT syndrome (LQTS) fails to identify mutations in approximately 25% of subjects with inherited LQTS. Large gene deletions and duplications can be missed with

Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia.

Cornelis M van Tilburg et al.

Clinical epigenetics, 11(1), 188-188 (2019-12-12)

Until today, adult and pediatric clinical trials investigating single-agent or combinatorial HDAC inhibitors including vorinostat in solid tumors have largely failed to demonstrate efficacy. These results may in part be explained by data from preclinical models showing significant activity only

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