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关键词:'59-49-4'
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Design of effective systems for controlled radical polymerization of styrene: Application of 4, 49-dimethyl and 5, 59-dimethyl 2, 29-bipyridine copper (II) complexes.
Schubert US, et al.
Macromolecular Rapid Communications, 20, 351-355 (1999)
H F Harbo et al.
Tissue antigens, 53(1), 106-110 (1999-03-19)
The human cytotoxic T-lymphocyte-associated protein 4 (CTLA4) gene may be a candidate susceptibility gene in multiple sclerosis (MS). In this study the distribution of the dimorphisms of exon 1 (+49 A/G) and promoter (-318 C/T) regions of the CTLA4 gene
A Rivera-Sagredo et al.
Carbohydrate research, 221, 37-47 (1991-12-16)
The 1H- and 13C-n.m.r. spectra of solutions of methyl beta-lactoside (1), all of its monodeoxy derivatives (2, 3, 6-10), the 3-O-methyl derivative (4), and methyl 4-O-beta-D-galactopyranosyl-D-xylopyranoside (5) in methyl sulfoxide-d6 have been analysed. The n.O.e.'s and specific desheildings indicate similar
T Yanagawa et al.
The Journal of rheumatology, 27(12), 2740-2742 (2000-12-29)
To examine whether CTLA-4 gene confers susceptibility to rheumatoid arthritis (RA) in Japanese. We investigated the distribution of a CTLA-4 gene polymorphism in 85 Japanese patients with RA and 200 controls. An A/G transition at position 49 of exon 1
Frank Giton et al.
European journal of endocrinology, 165(6), 917-924 (2011-09-29)
Differences in circulating steroid hormone levels have been hypothesized to explain ethnic differences in steroid-related diseases. The aim of this study was to determine the serum levels of a wide panel of steroid hormones, both androgens and estrogens, in healthy
Anas Hamadeh et al.
The American journal of cardiology, 131, 1-6 (2020-08-01)
There is limited information regarding clinical characteristics and outcomes of patients with SARS-CoV-2 (COVID-19) disease presenting with ST-segment elevation myocardial infarction (STEMI). In this multicenter retrospective study, we reviewed charts of patients admitted with symptomatic COVID-19 infection and STEMI to
N Sallakci et al.
Clinical and experimental dermatology, 30(5), 546-550 (2005-07-28)
Genetic factors predisposing individuals to Behçet's disease (BD) are considered to play important roles in the development of the disease. Patients with BD exhibit elevated levels of pro-inflammatory cytokines, and affected organs show a significant neutrophil and lymphocyte infiltration. Current
Sarah L Nolin et al.
American journal of human genetics, 72(2), 454-464 (2003-01-17)
The CGG repeat in the 5' untranslated region of the fragile X mental retardation 1 gene (FMR1) exhibits remarkable instability upon transmission from mothers with premutation alleles. A collaboration of 13 laboratories in eight countries was established to examine four
S Benedini et al.
Transplantation proceedings, 39(5), 1580-1585 (2007-06-21)
Natriuretic peptides are useful markers for risk stratification of patients with heart disease. However, conflicting results have been reported about circulating atrial natriuretic peptide (ANP) concentration in heart transplant recipients. To ascertain the effects of diabetes and acute insulin administration
Ammar Madania et al.
Clinical biochemistry, 43(10-11), 836-842 (2010-04-13)
Adaptation of a low-cost protocol to diagnose large rearrangements of the dystrophin gene in DMD/BMD Syrian patients and to establish the distribution of these mutations in the 2 hotspots. gDNA from 51 unrelated Syrian DMD/BMD male patients was isolated and
Kaiyong Mei et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(12), 1628-1636 (2009-10-13)
Primary germ cell tumors of the central nervous system (CNS) sometimes pose diagnostic difficulty. In this study we analyzed the diagnostic utility of a novel marker, SALL4, in 77 such tumors (59 pure and 18 mixed) consisting of the following
J A Sandberg et al.
The Journal of pharmacology and experimental therapeutics, 258(2), 477-482 (1991-08-01)
The pharmacokinetics of cocaine (COC) were studied during late gestation in guinea pigs. Clearance (Cl) was not dose-dependent and the average +/- S.D. was 59 +/- 16 ml/min/kg over the i.v. dose range of 2 to 12 mg/kg. Volume of
N Yingsakmongkol
Journal of wound care, 22(3), 130-132 (2013-05-15)
To study clinical outcomes and safety of WF I 0 as an adjunct to standard treatment for diabetic foot ulcers (DFU) and to determine the optimal number of WF I 0 cycles that should be administered. A prospective, open-label study
Peng Wang et al.
American journal of clinical pathology, 134(4), 604-612 (2010-09-22)
We immunohistochemically evaluated UTF1 in 104 primary and 68 metastatic testicular germ cell tumors and 339 non-germ cell tumors. The percentage of tumor cells stained was semiquantitatively scored (0, no tumor cell staining; 1+, ≤30% of cells; 2+, 31%-60% of
Roy F Chemaly et al.
Journal of pediatric hematology/oncology, 36(6), e376-e381 (2013-12-12)
Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections (LRTIs) in children, especially those with cancer. Data on RSV infections in this vulnerable population is limited. We conducted a retrospective study of all RSV infections in
K A Cummins et al.
Journal of dairy science, 87(5), 1428-1431 (2004-08-05)
Sixteen multiparous Jersey cows were assigned at calving to one of 4 dietary treatments. An 18% crude protein (CP) diet was fed as a total mixed ration through 30 d in milk (DIM), and beginning at 31 DIM a 9
Mônica Wanderley Monçores Velloso et al.
Nitric oxide : biology and chemistry, 22(3), 220-225 (2010-01-19)
Brazilian population has a multi-ethnical profile and the prevalence of endothelial nitric oxide synthase enzyme (eNOS) polymorphism in heart failure (HF) has not been previously studied. Therefore the present study assessed the association of eNOS Glu298Asp polymorphism in patients with
K A Cummins et al.
Journal of dairy science, 87(5), 1428-1431 (2004-08-05)
Sixteen multiparous Jersey cows were assigned at calving to one of 4 dietary treatments. An 18% crude protein (CP) diet was fed as a total mixed ration through 30 d in milk (DIM), and beginning at 31 DIM a 9
Haijiao Yu et al.
Oncology letters, 20(1), 317-325 (2020-06-23)
Circulating tumour cells (CTCs) have potential utility in various clinical applications for cancer management. The present study focused on evaluating the diagnostic role of CTCs in colorectal cancer (CRC). A total of 89 blood samples from 59 patients diagnosed with
Winston W Tan et al.
Urology, 81(1), 150-154 (2013-01-01)
To investigate whether prostate cancer patients receiving leuprolide demonstrated objective cognitive decline accompanied by a change in plasma levels of amyloid-β. Between November 19, 2003, and July 21, 2008, we prospectively enrolled 50 patients with biochemical recurrence of prostate cancer
P Sabbatini et al.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 17(3), 589-594 (2007-02-16)
The objective of this study was to analyze retrospective populations with recurrent ovarian cancer to assess differences in CA-125 patterns during chemotherapy. The populations included all patients treated between January 1994 and January 2004, who received liposomal doxorubicin and topotecan
Suzanne D DeBrosse et al.
Molecular genetics and metabolism, 107(3), 394-402 (2012-10-02)
Pyruvate dehydrogenase complex (PDC) deficiency is a relatively common mitochondrial disorder that primarily presents with neurological manifestations and lactic acidemia. We analyzed the clinical outcomes and neurological features of 59 consented symptomatic subjects (27 M, 32 F), who were confirmed
Yoshiaki Oshima et al.
Masui. The Japanese journal of anesthesiology, 54(8), 875-880 (2005-08-18)
Continuous epidural administration of droperidol at 2.5 mg x day(-1) or less was performed in 837 patients after surgery. In 4 of these patients, an extrapyramidal reaction occurred. Patient 1 was a 10-year-old girl who developed the symptom 29 hours
Curtis L Hedberg et al.
The Pediatric infectious disease journal, 23(5), 424-428 (2004-05-08)
Sepsis commonly complicates the clinical course of critically ill very low birth weight infants, with as many as 30% developing hospital-acquired bacteremia. The tumor necrosis factor alpha (TNF-alpha) -- 308 G/A single nucleotide polymorphism (SNP) is associated with adverse outcome
Marie Soegaard et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(12), 3761-3767 (2008-06-19)
To evaluate the prevalence of BRCA1 and BRCA2 mutations and associations with clinical correlates of disease in a population-based series of ovarian cancer cases from Denmark. DNA sequencing and multiplex ligation-dependent probe amplification analysis were used to analyze the BRCA1
Sun Hee Lee et al.
Annals of nutrition & metabolism, 56(1), 52-58 (2009-12-24)
The relationship between glutathione S-transferase (GST) polymorphisms and susceptibility to smoking-induced oxidative damage was investigated in healthy Korean smokers. Forty-nine healthy male smokers (20-59 years) participated in the study. GSTT1 and GSTM1 genotypes were determined, and lymphocyte DNA damage was
Hans Dieter Nischalke et al.
AIDS (London, England), 24(13), 2001-2007 (2010-07-01)
Cytotoxic lymphocyte antigen 4 (CTLA4), a co-receptor expressed on T lymphocytes, is involved in the regulation of T-cell functions. Here, we analyzed the potential impact of the CTLA4 polymorphisms on response to hepatitis C virus (HCV)-specific treatment in HIV(+) patients
Orhun H Kantarci et al.
Journal of neuroimmunology, 134(1-2), 133-141 (2003-01-01)
We comprehensively screened CTLA4 for novel genetic variations in patients with MS. We studied genetic variations by association methods in a population-based sample of 122 sporadic patients with MS and 244 age-, gender- and ethnicity-matched controls, and by linkage and
M Bajzová et al.
Physiological research, 57(6), 927-934 (2007-12-07)
Retinol binding protein 4 (RBP4) is a novel adipokine which might be involved in the development of insulin resistance. The aim of the study was to investigate the expression of RBP4 mRNA in subcutaneous and visceral fat depots and the
Guillaume Cayla et al.
Archives of cardiovascular diseases, 101(11-12), 743-751 (2008-12-09)
Clopidogrel fails to elicit an adequate antiplatelet response in 4-30% of patients. Assessing the phosphorylation of intraplatelet vasodilator-stimulated phosphoprotein (VASP) is an easy and reliable method of evaluating biological response to clopidogrel. To assess the prognostic value of clopidogrel in
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