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Increased levels of osteopontin in sputum supernatant in patients with COPD.

Anastasia Papaporfyriou et al.

Chest, 146(4), 951-958 (2014-06-06)

Osteopontin (OPN) is a phosphorylated acidic glycoprotein that can function as both an extracellular matrix molecule and a cytokine. Published data support that OPN is upregulated in surgical lung tissue samples of patients with COPD. The aim of this study

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