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Excretion profile of hydrocodone, hydromorphone and norhydrocodone in urine following single dose administration of hydrocodone to healthy volunteers.

Sandra Valtier et al.

Journal of analytical toxicology, 36(7), 507-514 (2012-07-12)

Abuse of prescription opioids for non-medical use has been on the rise over the past decade. The most commonly abused opioid is hydrocodone, a frequently prescribed pain medication metabolized by the body to hydromorphone, norhydrocodone and other minor metabolites. This

Biomonitoring following a chemical incident with acrylonitrile and ethylene in 2008.

Gabriele Leng et al.

Toxicology letters, 231(3), 360-364 (2014-06-25)

The analytical determination of hemoglobin adducts was used as an effective biomonitoring tool after a fire outbrake at a chemical plant close to Cologne/Germany in 2008. More than 1000 people (e.g. fire-men, police officers, and workers) were potentially exposed to

Role of endogenous vascular endothelial growth factor in endothelium-dependent vasodilation in humans.

Anna M J Thijs et al.

Hypertension (Dallas, Tex. : 1979), 61(5), 1060-1065 (2013-03-20)

Angiogenesis inhibitors have remarkably improved the outcome of patients with several types of cancer. Hypertension is the most reported side effect of angiogenesis inhibitors interfering with vascular endothelial growth factor signaling. In this study, we test the hypothesis that circulating

Mouse liver P450Coh: genetic regulation of the pyrazole-inducible enzyme and comparison with other P450 isoenzymes.

M A Lang et al.

Archives of biochemistry and biophysics, 271(1), 139-148 (1989-05-15)

Genetic experiments with two inbred strains of mice, AKR/J and DBA/2N, show a single major gene inheritance of additive mode for pyrazole-inducible coumarin 7-hydroxylase. Intragroup variation in the enzyme activity further suggests the contribution of minor modifying genes to the

Differential intensity-dependent effects of pulsed electromagnetic fields on RANKL-induced osteoclast formation, apoptosis, and bone resorbing ability in RAW264.7 cells.

Pan Wang et al.

Bioelectromagnetics, 38(8), 602-612 (2017-07-26)

Pulsed electromagnetic fields (PEMF) have been proven to be effective for promoting bone mass and regulating bone turnover both experimentally and clinically. However, the exact mechanisms for the regulation of PEMF on osteoclastogenesis as well as optical exposure parameters of

Financial incentives for smoking cessation in pregnancy: randomised controlled trial.

David Tappin et al.

BMJ (Clinical research ed.), 350, h134-h134 (2015-01-30)

To assess the efficacy of a financial incentive added to routine specialist pregnancy stop smoking services versus routine care to help pregnant smokers quit. Phase II therapeutic exploratory single centre, individually randomised controlled parallel group superiority trial. One large health

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