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关键词:'61941'
显示 1-30 共 363 条结果 关于 "61941" 范围 论文
Hyunryung Kim et al.
Materials science & engineering. C, Materials for biological applications, 40, 324-335 (2014-05-27)
Electrospun silk fibroin (SF) scaffolds provide large surface area, high porosity, and interconnection for cell adhesion and proliferation and they may replace collagen for many tissue engineering applications. Despite such advantages, electrospun SF scaffolds are still limited as bone tissue
Lara Mouttham et al.
Journal of assisted reproduction and genetics, 32(8), 1239-1250 (2015-08-08)
The objective of this study is to characterize the impact of exposure to cryoprotectants followed by vitrification on primordial follicle survival and activation using a fetal bovine model. In the first study, fetal bovine cortical pieces were exposed to cryoprotectants
Raquel García-González et al.
Talanta, 142, 11-19 (2015-05-25)
Amplification-free (referring to enzymatic amplification step) detection methodologies are increasing in biosensor development due to the need of faster and simpler protocols. However, for maintaining sensitivity without this step, highly detectable molecules or very sensitive detection techniques are required. The
Sebastian Daum et al.
Biological chemistry, 395(7-8), 801-812 (2014-07-09)
As shape transformations of membranes are vital for intracellular trafficking, it is crucial to understand both the mechanics and the biochemistry of these processes. The interplay of these two factors constitutes an experimental challenge, however, because biochemical experiments are not
Joanna L Workman et al.
Psychoneuroendocrinology, 57, 37-50 (2015-04-23)
Chronic alcohol consumption negatively affects health, and has additional consequences if consumption occurs during pregnancy as prenatal alcohol exposure adversely affects offspring development. While much is known on the effects of prenatal alcohol exposure in offspring less is known about
L S R Marinho et al.
Reproduction in domestic animals = Zuchthygiene, 50(5), 807-811 (2015-08-19)
The pregnancy rates obtained after the transfer of cryopreserved in vitro-produced (IVP) embryos are usually low and/or inconsistent. The objective of this study was to evaluate the pregnancy rates of Holstein, Gyr and Holstein × Gyr cattle after the transfer
Birgit Oberleitner et al.
Chemical communications (Cambridge, England), 49(16), 1615-1617 (2013-01-23)
This work describes an integrated approach for designing on demand Self-Assembled Monolayers (SAMs) on silicon oxides and particularly glass substrates for cell biology applications. Starting from commercially available compounds, the strategy relies on thiol-ene reaction and provides high quality SAMs
Sebastijan Kovačič et al.
Macromolecular rapid communications, 36(17), 1605-1611 (2015-07-15)
Metal-organic frameworks (MOFs) nanoparticles in combination with a nonionic surfactant (Pluronic L-121) are used to stabilize dicyclopentadiene (DCPD)-in-water high internal phase emulsions (HIPEs). The resulting HIPEs containing the MIL-100(Fe) nanoparticles (MIL: Materials of Institut Lavoisier) at the interface between the
Huijuan Zhang et al.
ChemSusChem, 7(7), 2000-2006 (2014-03-22)
Herein, we introduce a peapod-like composite with Ni12 P5 nanoparticles encapsulated in carbon fibers as the enhanced anode in Li-ion batteries for the first time. In the synthesis, NiNH4 PO4 ⋅H2 O nanorods act as precursors and sacrificial templates, and
Youngjin Choi et al.
Langmuir : the ACS journal of surfaces and colloids, 31(23), 6457-6462 (2015-05-28)
Mesoporous silica has received considerable attention as a drug delivery vehicle because of its large surface area and large pore volume for loading drugs and large biomolecules. Recently, mesoporous silica microparticles have shown potential as a three-dimensional vaccine platform for
Shishuai Su et al.
ACS nano, 9(2), 1367-1378 (2015-01-23)
Effective therapeutics against triple negative breast cancer (TNBC), which has no standard-of-care therapy, needs to be developed urgently. Here we demonstrated a strategy of integrating indocyanine green (ICG), paclitaxel (PTX), and survivin siRNA into one thermosensitive poly(2-(2-methoxyethoxy)ethyl methacrylate-co-oligo(ethylene glycol) methacrylate)-co-2-(dimethylamino)ethyl
Hua Wang et al.
Analytical biochemistry, 467, 75-83 (2014-09-15)
Owing to the mounting evidence of serum lipid changes in atherosclerosis, there has been increasing interest in developing new methods for analyzing atherogenic lipoprotein profiles. The separation of lipoprotein and lipoprotein subclasses has been demonstrated using a microchip capillary electrophoresis
Divakar Jammalamadaka et al.
The American journal of the medical sciences, 339(3), 276-281 (2010-01-22)
In clinical practice, poisoning with ethylene glycol, methanol, and isopropyl alcohol is common. These alcohol-related intoxications can present with high anion gap metabolic acidosis and increased osmolality. Toxicity and clinical symptoms are due to the accumulation of their metabolites, causing
A V Nikolenko et al.
Cryo letters, 34(5), 527-534 (2014-01-23)
Oxyethyl derivatives of polyol class members such as glycerol and ethylene glycol with various polymerization degrees possess low toxicity and cryoprotective properties via an exocellular mechanism. To develop the cryoprotective media based on non-penetrating cryoprotectants, we studied cryoprotective and physico-chemical
Ines Castangia et al.
Colloids and surfaces. B, Biointerfaces, 132, 185-193 (2015-06-10)
The aim of this work was to formulate Santolina insularis essential oil-loaded nanocarriers, namely Penetration Enhancer containing Vesicles (PEVs), evaluate the physico-chemical features and stability, and gain insights into their ability to deliver the oil to the skin. S. insularis
Jenny P Rosengren-Holmberg et al.
Biomaterials science, 3(8), 1208-1217 (2015-07-30)
Heparin-imprinted synthetic polymer surfaces with the ability to attenuate activation of both the complement and the coagulation system in whole blood were successfully produced. Imprinting was achieved using a template coated with heparin, a highly sulfated glycosaminoglycan known for its
Gabriel Lassabe et al.
Analytical chemistry, 86(11), 5541-5546 (2014-05-07)
Small compounds cannot bind simultaneously to two antibodies, and thus, their immunodetection is limited to competitive formats in which the analyte is indirectly quantitated by measuring the unoccupied antibody binding sites using a competing reporter. This limitation can be circumvented
Corina Danciu et al.
Natural product communications, 10(6), 951-954 (2015-07-23)
In recent years polyurethane microstructures (PM) have gained increasing attention in the pharmaceutical field due to the importance of their practical application. Since finding that such a formulation with genistein could improve its applications, we have conducted a preliminary study
Elias Gebara et al.
Stem cell research, 14(3), 369-379 (2015-04-19)
Aging is associated with increased inflammation and reduced hippocampal neurogenesis, which may in turn contribute to cognitive impairment. Taurine is a free amino acid found in numerous diets, with anti-inflammatory properties. Although abundant in the young brain, the decrease in
Danica Ciric et al.
Journal of virology, 89(12), 6287-6293 (2015-04-10)
Prion diseases are characterized by conformational changes of a cellular prion protein (PrP(C)) into a β-sheet-enriched and aggregated conformer (PrP(Sc)). Shadoo (Sho), a member of the prion protein family, is expressed in the central nervous system (CNS) and is highly
[Metabolic acidosis--not always easy].
Hans Flaatten
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 133(23-24), 2487-2488 (2013-12-12)
Sravan Kumar Patel et al.
PloS one, 8(2), e55802-e55802 (2013-02-15)
Cylcooxgenase-2 (COX-2) expressing macrophages, constituting a major portion of tumor mass, are involved in several pro-tumorigenic mechanisms. In addition, macrophages are actively recruited by the tumor and represent a viable target for anticancer therapy. COX-2 specific inhibitor, celecoxib, apart from
Anthony W Wren et al.
Macromolecular bioscience, 15(8), 1146-1158 (2015-04-30)
Silver (Ag) coated bioactive glass particles (Ag-BG) were formulated and compared to uncoated controls (BG) in relation to glass characterization, solubility and microbiology. X-ray diffraction (XRD) confirmed a crystalline AgNP surface coating while ion release studies determined low Ag release
Bao-Dong Cai et al.
Journal of chromatography. A, 1406, 78-86 (2015-07-05)
Phytohormones, a collection of signal small molecules with various structures, regulate a series of physiological processes of plants. For instance, they regulate the growth and development, response to biotic and abiotic stresses. Quantification of trace endogenous phytohormones is essential to
Hilde Nelissen et al.
The Plant cell, 27(6), 1605-1619 (2015-06-04)
Most molecular processes during plant development occur with a particular spatio-temporal specificity. Thus far, it has remained technically challenging to capture dynamic protein-protein interactions within a growing organ, where the interplay between cell division and cell expansion is instrumental. Here
Nader Khodaee et al.
Talanta, 147, 59-62 (2015-11-26)
A simple solventless injection method was introduced based on the using of a solid-phase microextraction (SPME) fiber for injection of large amounts of the analytes extracted by the magnetic solid phase extraction (MSPE) procedure. The resulted extract from MSPE procedure
Giuseppe Gangarossa et al.
Hippocampus, 24(12), 1466-1481 (2014-07-22)
The acute activation of the dopamine D1-like receptors (D1R) is involved in a plethora of functions ranging from increased locomotor activity to the facilitation of consolidation, storage, and retrieval of memories. Although much less characterized, epileptiform activities, usually triggered by
Rachel R P Machado et al.
Tuberculosis (Edinburgh, Scotland), 95(6), 829-838 (2015-11-06)
Interferometry was used together with the conventional microplate resazurin assay to evaluate the antimycobacterial properties of essential oil (EO) from fruits of Pterodon emarginatus and also of rifampicin against Mycobacterium bovis. The aim of this work is not only to
G Cisbani et al.
Neurobiology of disease, 82, 430-444 (2015-08-02)
The neuroprotective properties of cystamine identified in pre-clinical studies have fast-tracked this compound to clinical trials in Huntington's disease, showing tolerability and benefits on motor symptoms. We tested whether cystamine could have such properties in a Parkinson's disease murine model
Masakazu Igarashi et al.
Neuroscience research, 96, 45-53 (2015-02-24)
The use of NR2B antagonists in Parkinsonism is still controversial. To examine their anti-parkinsonian effects, the NR2B antagonist, ifenprodil, and L-DOPA were administered together and separately in hemiparkinsonian rats (hemi-PD) that were subjected to a cylinder test. Recovery from hypoactivity
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