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显示 1-30 共 124 条结果 关于 "63-68-3" 范围 论文
Feng-yu Wang et al.
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 27(6), 644-649 (2010-12-15)
To investigate the characteristics of the phenylalanine hydroxylase (PAH) gene mutations in patients with phenylketonuria (PKU) in Henan province, China, in order for providing basic information for clinical genetic counseling and prenatal diagnosis. All the exons and partial flanking introns
Hélène Jacquet et al.
Human molecular genetics, 11(19), 2243-2249 (2002-09-10)
The increased prevalence of schizophrenia among patients with the 22q11 interstitial deletion associated with DiGeorge syndrome has suggested the existence of a susceptibility gene for schizophrenia within the DiGeorge syndrome chromosomal region (DGCR) on 22q11. Screening for genomic rearrangements of
Constantinos T Sofocleous et al.
Annals of surgical oncology, 19(13), 4262-4269 (2012-07-04)
To assess the predictive value of examinations of tissue adherent to multitined electrodes on local tumor progression-free survival (LPFS) and overall survival (OS) after liver tumor radiofrequency ablation (RFA). An institutional review board-approved, Health Insurance Portability and Accountability Act-compliant review
F B Whitfield et al.
Journal of agricultural and food chemistry, 49(2), 816-822 (2001-03-23)
The reaction of 4-hydroxy-5-methyl-3(2H)-furanone (HMF) with cysteine or hydrogen sulfide at pH 6.5 for 60 min at 140 degrees C produced complex mixtures of volatile compounds, the majority of these containing either sulfur or nitrogen. Of the 68 compounds detected
K Page et al.
British journal of cancer, 104(8), 1342-1348 (2011-03-24)
Human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in 20-25% of breast cancers. This study investigated circulating free DNA (cfDNA) for detection of HER2 gene amplification in patients with breast cancer. Circulating free DNA was extracted from
Lucio Gullo et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 9(3), 240-244 (2009-05-02)
Among the various studies of pancreatic function in the elderly published so far, none have dealt with subjects over 90 years of age. The aim of this study was to examine pancreatic function in healthy individuals over 90 years old.
Luca Valenti et al.
American journal of nephrology, 28(2), 311-316 (2007-11-21)
HFE protein controls iron absorption and cycling, and HFE mutations influence iron status. The aim was to evaluate the effect of the HFE genotype on the need for iron and erythropoietin in Italian hemodialysis patients. Ninety-six prevalent patients were evaluated
Terzah M Horton et al.
British journal of haematology, 186(2), 274-285 (2019-04-09)
While survival in paediatric acute lymphoblastic leukaemia (ALL) is excellent, survival following relapse is poor. Previous studies suggest proteasome inhibition with chemotherapy improves relapse ALL response rates. This phase 2 Children's Oncology Group study tested the hypothesis that adding the
Young Saing Kim et al.
Cancer chemotherapy and pharmacology, 73(1), 163-169 (2013-11-10)
Docetaxel, in combination with cisplatin or oxaliplatin, has demonstrated efficacy in advanced gastric cancer (AGC). This randomized, non-comparative phase II trial evaluated two weekly docetaxel-based regimens to determine which is the most promising in terms of efficacy and safety as
Carlos H Burgos et al.
Journal of the American Chemical Society, 127(22), 8044-8049 (2005-06-02)
The remarkable versatility and selectivity of the 10-(trimethylsilyl)-9-borabicyclo[3.3.2]decanes (10-TMS-9-BBDs) in the allyl- and crotylboration of representative aldehydes are reported. The new reagents are prepared through air-stable crystalline pseudoephedrine borinic ester complexes of the 10-TMS-9-BBDs (4), which are available in 63%
Xuan Jiang et al.
Biomacromolecules, 13(9), 2926-2932 (2012-08-09)
When grown in a nonanoic acid-limited chemostat at a dilution rate of 0.25 h(-1), Pseudomonas putida KT2440 produced poly(3-hydroxynonanoate-co-3-hydroxyheptanoate) containing 68 mol % 3-hydroxynonanoate (C9) and 32 mol % 3-hydroxyheptanoate (C7). Under the same conditions, but in the presence of
Martin Thomassen et al.
The Journal of physiology, 591(6), 1523-1533 (2013-01-30)
The aim of the present study was to examine fibre type-specific Na(+)-K(+) pump subunit expression and exercise-induced alterations in phospholemman (FXYD1) phosphorylation in humans. Segments of human skeletal muscle fibres were dissected and fibre typed, and protein expression was determined
Tanja Berger et al.
Folia microbiologica, 66(1), 87-98 (2020-09-26)
The potential of the culturable bacterial community from an Alpine coniferous forest site for the degradation of organic polymers and pollutants at low (5 °C) and moderate (20 °C) temperatures was evaluated. The majority of the 68 strains belonged to
P A Trimmer et al.
Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration, 5(3), 233-239 (1996-09-01)
We have examined MPTP toxicity to dopamine neurons of mice homozygous for a transgenic knockout of the p53 growth control gene (p53-/-). MPTP at a total dose of 96 mg/kg administered in four doses over two days produced a non-homogeneous
Andreas Teufel et al.
World journal of gastroenterology, 12(34), 5513-5516 (2006-09-29)
To report on our large German collective and updated data of 142 patients with autoimmune hepatitis (AIH) type 1. Key investigations performed were liver biopsy, serum autoantibodies as well as serum markers such as IgG and elevated transaminases. Antinuclear antigen
Timothy O'Brien et al.
BJU international, 112(8), 1096-1104 (2013-09-24)
To determine if photodynamic 'blue-light'-assisted resection leads to lower recurrence rates in newly presenting non-muscle-invasive bladder cancer (NMIBC). We conducted a prospective randomized trial of hexylaminolevulinate (HAL) photodynamic diagnosis (PDD)-assisted transurethral resection of bladder tumour (TURBT) plus single-shot intravesical mitomycin
Laura Detti et al.
Fertility and sterility, 100(3), 889-894 (2013-06-29)
To determine the effects of different hormonal levels on endometrial biochemical development during ovulation induction for assisted reproduction technology (ART) cycles. Prospective controlled study. University center. Nine women during a natural cycle (control) and 9 oocyte donors (treated) during an
E Faure et al.
The Journal of biological chemistry, 271(48), 30571-30575 (1996-11-29)
Anti-Müllerian hormone, a member of the transforming growth factor beta superfamily, produces early regression of Müllerian ducts in the male fetus through binding to a serine/threonine kinase receptor, homologous to type II receptors of the transforming growth factor beta (TGF-beta)
Li-Dong Wang et al.
World journal of gastroenterology, 9(7), 1394-1397 (2003-07-11)
To characterize cytochrome P4501A1 (CYP1A1), glutathione S-transferases (GSTs) and microsomal epoxide hydrolase (mEH) polymorphisms in Chinese esophageal cancer patients. Multiplex polymerase chain reaction (PCR) and PCR based restriction fragment length polymorphisms (PCR-RFLP) were used to detect polymorphism changes of CYP
Ipatia A Doussis-Anagnostopoulou et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(6), 1759-1766 (2008-03-19)
To correlate the immunohistochemical expression of topoisomerase IIalpha (topoIIalpha) in Hodgkin's lymphoma (HL) with clinicopathological parameters, the expression of Ki-67 and the outcome of patients, who had been homogenously treated with ABVD or equivalent regimens. Immunohistochemistry using the monoclonal antibody
Etual Espinosa-Cárdenas et al.
Endocrine, 70(1), 143-149 (2020-06-18)
Treatment with dopamine agonists (DA) is highly effective in patients with prolactinomas. In selected patients, discontinuation of DA after several years of successful treatment is possible, however, hyperprolactinemia recurs in 60-80% of them. It is unclear what is the clinical
J L Fowlkes et al.
The Journal of biological chemistry, 269(41), 25742-25746 (1994-10-14)
Insulin-like growth factor binding protein-3 (IG-FBP-3) is degraded by a Zn(2+)-dependent protease(s) produced by human dermal fibroblasts in vitro (Fowlkes, J. (1994) Endocrine J. 2, 63-68). Initial studies using IG-FBP-3-substrate zymography identified several IGFBP-3-degrading proteases with M(r) 52,000-72,000, which were
Pavel Kramata et al.
Carcinogenesis, 26(11), 1965-1974 (2005-06-25)
Irradiation of SKH-1 mice with UVB light for 20 weeks resulted in a large number of patches of epidermal cells, which was visualized with an antibody that recognizes mutated p53 protein. Oral treatment of mice with caffeine (0.4 mg/ml) or
Daun Jung et al.
Journal of applied toxicology : JAT, 36(9), 1129-1136 (2015-12-23)
In vitro testing methods for classifying sensitizers could be valuable alternatives to in vivo sensitization testing using animal models, such as the murine local lymph node assay (LLNA) and the guinea pig maximization test (GMT), but there remains a need
Yuichiro Izumi et al.
Japanese journal of radiology, 33(8), 461-470 (2015-06-24)
To evaluate the results of uterine artery embolization (UAE) for symptomatic uterine leiomyoma by use of porous gelatin particles (PGP) in comparison with conventional hand-cut gelatin sponge particles. One hundred and fifteen consecutive patients who had undergone UAE were retrospectively
S M Thompson et al.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 25(1), 108-111 (2016-08-06)
Injury to the proximal hamstring complex (PHC) is becoming more frequently diagnosed. Patients attending our tertiary referral centre demonstrated 'pathological changes' in the unaffected normal contralateral PHC on MRI. The prevalence of PHC pathology, however, has not been previously documented
Karoline Bleymehl et al.
Medical microbiology and immunology, 200(3), 193-202 (2011-03-05)
The treatment of varicella-zoster virus (VZV) reactivation is based on nucleoside analogues acyclovir (ACV) and bromevinyldeoxyuridine (BVdU) and a phosphonic acid derivative (PFA). Drug-resistant mutants of 3 wild-type (WT) VZV strains were obtained by exposure of human retinal pigment epithelial
Y Zheng et al.
The Journal of biological chemistry, 269(48), 30313-30319 (1994-12-02)
2'-O-[(R)-Formyl(adenin-9-yl)-methyl]-(S)-glyceraldehyde 3'-triphosphate (also designated as ATP dialdehyde or ATPDA) was utilized as an affinity label for the 3'-phosphoadenosine 5'-phosphosulfate (PAPS) binding site of an aryl sulfotransferase. The sulfotransferase employed in these studies was rat hepatic aryl sulfotransferase (AST) IV (also
Jia Liu et al.
Experimental and therapeutic medicine, 10(5), 1947-1952 (2015-12-08)
The main obstacle in the development of an effective tumor vaccine is the inherent ability of tumors to evade immune responses. Tumors often use common immune mechanisms and regulators to evade the immune system. The present study aimed to analyze
Akira Inoue et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 27(9), 1394-1400 (2009-02-20)
This multicenter phase II study was undertaken to investigate the efficacy and feasibility of gefitinib for patients with advanced non-small-cell lung cancer (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations without indication for chemotherapy as a result of poor performance
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