Merck
CN
Search Within

63768

应用筛选条件
关键词:'63768'
显示 31-60 共 70 条结果 关于 "63768" 范围 论文
T. Bartok et al.
Journal of Liquid Chromatography, 17, 4391-4391 (1994)
Wei Wang et al.
Journal of neuroscience research, 90(6), 1218-1229 (2012-02-23)
Serine racemase (SR) is the only identified enzyme in mammals responsible for isomerization of L-serine to D-serine, a coagonist at N-methyl-D-aspartate (NMDA) receptors in the forebrain. Our previous data showed that an apparent SR dimer resistant to sodium dodecyl sulfate
Ana Raquel Santos et al.
Methods in molecular biology (Clifton, N.J.), 906, 435-449 (2012-07-14)
Like most of the new technologies designed to interact with biological systems, the applications of -nanomaterials needs a proper assessment for their potential impacts. It is only through addressing the issues raised by toxicological studies that nanotechnology will be able
Zuzana Bubelová et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 50(11), 797-808 (2015-09-12)
The aim of this study was to evaluate the combined effect of temperature (10, 20 and 37°C), pH (4, 5, 6, 7 and 8), and NaCl content (0, 1, 3, 4, 5 and 6% w/v) on the growth and putrescine
Jing Wang et al.
Talanta, 89, 422-426 (2012-01-31)
Aiming to find an alternative electrochemiluminescence (ECL) quenching route of high efficiency, biocatalytic precipitation (BCP) was firstly coupled with ECL for investigating its insulating effect on ECL. Experimental data revealed that an insulating layer could be formed via BCP onto
Celeste R Brennecka et al.
Journal of neurosurgery, 119(1), 228-238 (2013-04-09)
Over the past 20 years, endovascular embolization has become the preferred method of treating cerebral aneurysms. While there are many embolic devices on the market, none is ideal. In this study the authors investigated the use of a liquid-to-solid gelling
Uma M Bhalerao et al.
Colloids and surfaces. B, Biointerfaces, 125, 151-159 (2014-12-09)
Herein we report the in-vitro controlled release properties of 1, 3, 5-trisubstituted-2-pyrazolines through Layer-by-Layer (LbL) self assembled thin films fabricated from chitosan and heparin sodium salt as biocompatible polyelectrolytes. This study was carried out as a preliminary step towards the
Yoshikazu Ishii et al.
Antimicrobial agents and chemotherapy, 54(9), 3625-3629 (2010-07-08)
ME1071, a maleic acid derivative, is a novel specific inhibitor for metallo-beta-lactamases (MBL). In this study, the potentiation of ME1071 in combination with several beta-lactams was evaluated using MBL-producing Pseudomonas aeruginosa isolates. The rates of susceptibility of MBL producers to
D Kutlán et al.
Journal of chromatography. A, 949(1-2), 235-248 (2002-05-10)
A comprehensive evaluation of papers dealing with the HPLC quantitation of amines as o-phthaldialdehyde (OPA) derivatives has been given and discussed in details. The stability and characteristics of selected representatives of mono [methyl-, ethyl-, n-/isopropyl, n-/isobutyl-, tert.-butyl-, sec.-butyl-, isoamyl amines
Oliva M Primera-Pedrozo et al.
Nanoscale, 4(4), 1312-1320 (2012-01-26)
An aqueous route of synthesis is described for rapid synthesis of lead selenide quantum dots (PbSe QDs) at room temperature in an attempt to produce water-soluble and stable nanocrystals. Several thiol-ligands, including thioglycolic acid (TGA), thioglycerol (TGC), 3-mercaptopropionic acid (MPA)
Patrick R Brown et al.
ACS nano, 8(6), 5863-5872 (2014-05-16)
The electronic properties of colloidal quantum dots (QDs) are critically dependent on both QD size and surface chemistry. Modification of quantum confinement provides control of the QD bandgap, while ligand-induced surface dipoles present a hitherto underutilized means of control over
Mao Shen et al.
Nanoscale research letters, 9(1), 558-558 (2014-10-21)
In this paper, we investigated the functional imaging properties of magnetic microspheres composed of magnetic core and CdTe quantum dots in the silica shell functionalized with folic acid (FA). The preparation procedure included the preparation of chitosan-coated Fe3O4 nanoparticles (CS-coated
Yakup Aykut et al.
ACS applied materials & interfaces, 4(8), 3837-3845 (2012-07-18)
We report on the microstructural crystal phase transformation of electrospun TiO(2) nanofibers generated via sol-gel electrospinning technique, and the incorporation of as-synthesized CdSe quantum dots (QDs) to different phases of TiO(2) nanofibers (NFs) via bifunctional surface modification. The effect of
Justin D Besant et al.
Nature communications, 6, 6978-6978 (2015-04-23)
Diagnosis of disease outside of sophisticated laboratories urgently requires low-cost, user-friendly devices. Disposable, instrument-free testing devices are used for home and physician office testing, but are limited in applicability to a small class of highly abundant analytes. Direct, unambiguous visual
Zhanxi Fan et al.
Nature communications, 6, 6571-6571 (2015-03-15)
Conventionally, the phase transformation of inorganic nanocrystals is realized under extreme conditions (for example, high temperature or high pressure). Here we report the complete phase transformation of Au square sheets (AuSSs) from hexagonal close-packed (hcp) to face-centered cubic (fcc) structures
Feng Jiang et al.
Langmuir : the ACS journal of surfaces and colloids, 28(36), 12931-12940 (2012-08-14)
A strong ligand effect was observed for the aqueous-phase growth of ZnSe quantum dots (QDs) in the Ostwald ripening (OR) stage. The QDs were made by injecting Se monomer at room temperature followed by a ramp to 100 °C. The
Estefanía de Munck et al.
Environmental toxicology and pharmacology, 39(3), 1232-1245 (2015-05-24)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscle paralysis that reflects the motoneurons' degeneration. Several studies support the relationship between β-N-methylamino-l-alanine (l-BMAA), a neurotoxic amino acid produced by cyanobacteria and diatoms, and the sporadic occurrence of
Siyi Hu et al.
The Analyst, 139(18), 4681-4690 (2014-07-24)
Biofunctionalized quantum dots (QDs), especially protein-coated QDs, are known to be useful targeted fluorescent labels for cellular and deep-tissue imaging. These nanoparticles can also serve as efficient energy donors in fluorescence resonance energy transfer (FRET) binding assays for the multiplexed
Ramesh Chennupati et al.
PloS one, 9(7), e102264-e102264 (2014-07-18)
Argininosuccinate synthetase (ASS) is essential for recycling L-citrulline, the by-product of NO synthase (NOS), to the NOS substrate L-arginine. Here, we assessed whether disturbed arginine resynthesis modulates endothelium-dependent vasodilatation in normal and diabetic male mice. Endothelium-selective Ass-deficient mice (Assfl/fl/Tie2Cretg/- = Ass-KOTie2) were
Imad Younus Hasan et al.
Soft matter, 11(27), 5571-5579 (2015-06-16)
For studies involving biomimetic phospholipid membrane systems, such as membrane-protein interactions, it is crucial that the supported membrane is biomimetic in its physical properties as well as in its composition. Two often overlooked aspects of biomimicry are the need for
Zoltan Nemeth et al.
PloS one, 10(8), e0135498-e0135498 (2015-08-28)
Pericardial fluid (PF) contains several biologically active substances, which may provide information regarding the cardiac conditions. Nitric oxide (NO) has been implicated in cardiac remodeling. We hypothesized that L-arginine (L-Arg) precursor of NO-synthase (NOS) and asymmetric dimethylarginine (ADMA), an inhibitor
Meng-Nan Ma et al.
Analytical chemistry, 87(22), 11389-11397 (2015-10-13)
A highly sensitive electrochemiluminescent (ECL) aptasensor was constructed using semicarbazide (Sem) as co-reaction accelerator to promote the ECL reaction rate of CdTe quantum dots (CdTe QDs) and the co-reactant of peroxydisulfate (S2O8(2-)) for boosting signal amplification. The co-reaction accelerator is
Wafa M Elbjeirami
Kidney international, 80(11), 1115-1117 (2011-11-16)
Interstitial fibrosis plays a major role in the progression of renal diseases. Peroxisome proliferator-activated receptor-α (PPAR-α) ligands are increasingly explored for their potential to reverse or halt tubulointerstitial fibrosis. This Commentary discusses new findings by Boor et al., who show
Jaco Franken et al.
Applied microbiology and biotechnology, 99(15), 6377-6389 (2015-04-09)
Industrial synthesis of L-carnitine is currently performed by whole-cell biotransformation of industrial waste products, mostly D-carnitine and cronobetaine, through specific bacterial species. No comparable system has been established using eukaryotic microorganisms, even though there is a significant and growing international
Qijin Wan et al.
Colloids and surfaces. B, Biointerfaces, 104, 181-185 (2013-01-15)
In order to construct a three-dimensional electrode, in situ electrochemical deposition of gold nanoparticles onto a gold electrode coated with a self-assembled monolayer of 3-mercaptopropionic acid (Au NP/MPA/Au) was conducted. Horseradish peroxidase (HRP) was then immobilized into this three-dimensional electrode
Ramprasad Kandavar et al.
Journal of clinical hypertension (Greenwich, Conn.), 17(1), 14-19 (2014-12-17)
Prehypertension is an important phenotype for cardiovascular risk and development of established hypertension. To better understand the early circulatory changes in this group, the authors studied 34 patients with prehypertension (blood pressure 120-139/80-89 mm Hg) using digital plethysmography for measurement
Md Ashaduzzaman et al.
Biosensors & bioelectronics, 73, 100-107 (2015-06-10)
Regeneration is a key goal in the design of immunosensors. In this study, we report the temperature-regulated interaction of N-isopropylacrylamide (PNIPAAm) functionalised cardiac troponin T (cTnT) with anti-cTnT. Covalently bonded PNIPAAm on an anti-cTnT bioelectrode showed on/off-switchability, regeneration capacity and
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonists: from bench to bedside.
Henri Mattes et al.
Journal of medicinal chemistry, 53(15), 5367-5382 (2010-04-02)
S Sofia M Rodrigues et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 16(9), 1880-1888 (2015-04-25)
Immobilization of quantum dots (QDs) onto solid supports could improve their applicability in the development of sensing platforms and solid-phase reactors by allowing the implementation of reusable surfaces and the execution of repetitive procedures. As the reactivity of QDs relies
Rijun Gui et al.
Talanta, 94, 295-300 (2012-05-23)
Rhodamine 6G (R6G) and 3-mercaptopropionic acid (MPA) capped-CdTe quantum dots (QDs) were conjugated by electrostatic interactions in aqueous solution. The R6G-QDs conjugate was utilized as a photoluminescence (PL) ratiometric sensor for the detection of glutathione (GSH). In this method, intentional
2/3