CN
Search Within
67-66-3
应用筛选条件
关键词:'67-66-3'
显示 1-30 共 108 条结果 关于 "67-66-3" 范围 论文
Xiaolin Cao et al.
The Analyst, 142(14), 2640-2647 (2017-06-15)
Surface-enhanced Raman scattering (SERS) has been widely used in the detection of targets and strongly depends on the interaction and the distance between the targets and nanoparticles. Herein, metal-organic frameworks (MOFs) were first easily synthesized on a large scale via
Ming Yu et al.
Biochemical and biophysical research communications, 371(1), 10-15 (2008-04-09)
The pro-apoptotic protein Bax is instable in many cancer cells but the mechanism of Bax degradation remains unclear. Four different lengths of deductive Bax degradation sensitive (BDS) sequences within BH3-BH1 region, BDS-1 (Bax 67-124), BDS-3 (Bax 74-107), BDS-5 (Bax 67-107)
So Hee Park et al.
Archives of pharmacal research, 42(9), 790-814 (2018-06-28)
The aim of this work was to evaluate the synthesis and structure-activity relationship of 4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl 2-phenylacetate derivatives as potential wound-healing agents. The IC50 values of the lead compounds ranged from 0.01 to 0.05 µM. These compounds also increased the levels of
Toshiyuki Fujii et al.
The journal of physical chemistry. A, 114(7), 2543-2552 (2010-02-04)
This work reports on the chemical isotope fractionation of Zn(II) by a solvent extraction method with the crown ether dicyclohexano-18-crown-6. The (m)Zn/(64)Zn ratios (m = 66, 67, and 68) were analyzed by multiple-collector inductively coupled plasma mass spectrometry. The relative
Irina Isakova-Sivak et al.
PloS one, 9(7), e102339-e102339 (2014-07-25)
H2N2 Influenza A caused the Asian flu pandemic in 1957, circulated for more than 10 years and disappeared from the human population after 1968. Given that people born after 1968 are naïve to H2N2, that the virus still circulates in
R E Kohlmeier et al.
Southern medical journal, 93(11), 1073-1077 (2000-11-30)
Venous thrombosis followed by pulmonary embolism is one of the most common causes of sudden death among middle-aged adults. Several inherited polymorphisms are associated with heightened risk of venous thrombosis, including mutation at position 20210 of the prothrombin gene and
M Duchrow et al.
Cell proliferation, 29(1), 1-12 (1996-01-01)
The human antigen defined by the monoclonal antibody Ki-67, the 'Ki-67 protein', is an ubiquitously expressed human nuclear protein strictly associated with cell proliferation and is widely used in routine pathology as a 'proliferation marker' to measure the growth fraction
Usha Gundimeda et al.
Journal of neurochemistry, 132(1), 70-84 (2014-10-15)
Axonal regeneration after injury to the CNS is hampered by myelin-derived inhibitors, such as Nogo-A. Natural products, such as green tea, which are neuroprotective and safe for long-term therapy, would complement ongoing various pharmacological approaches. In this study, using nerve
Yunpeng Cai et al.
The journal of gene medicine, 20(7-8), e3025-e3025 (2018-05-26)
Antisense gapmer oligonucleotide drugs require delivery and biodistribution enabling technologies to increase in vivo efficacy. An attractive approach is their binding and consequent transport by the endogenous human serum albumin pool as mediated by fatty acid incorporation into the gapmer
I Sarto et al.
Neuropharmacology, 43(4), 482-491 (2002-10-09)
GABA(A) receptors are the major inhibitory transmitter receptors in the central nervous system. The majority of these receptors is composed of two alpha, two beta and one gamma subunit that assemble around an aqueous pore and form an intrinsic chloride
Michel R Nasr et al.
The American Journal of dermatopathology, 30(2), 117-122 (2008-03-25)
Differentiating malignant melanoma from benign melanocytic lesions can be challenging. We undertook this study to evaluate the use of the immunohistochemical mitosis marker phospho-Histone H3 (pHH3) and the proliferation markers Ki-67 and survivin in separating malignant melanoma from benign nevi.
Hussein Fakhry et al.
Human pathology, 41(6), 848-858 (2010-02-25)
Overexpression of histone deacetylases has been reported in various human malignancies; however, the expression of histone deacetylases in endometrial tissue is not fully understood. In the present study, the expression of histone deacetylase 1, histone deacetylase 2, and Ki-67 was
Chikashi Kobayashi et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 19(4), 524-532 (2006-03-24)
Mitotic checkpoint maintains genomic integrity before mitosis. Numerous observations have suggested that mitotic abnormalities produce chromosomal instability and aneuploidy. In MPNST, complex karyotypes showing numerical and structural aberrations have been described. 'Checkpoint with forkhead-associated domain and ring finger' (CHFR) was
Shau-Hsuan Li et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(4), 497-507 (2007-03-27)
Despite improvement in surgical techniques, prognosis of gallbladder carcinoma remains poor. It is desirable to identify prognostic biomarkers to aid in the development of targeted therapeutic strategies. Two SCF(Skp2) ubiquitin ligase-related proteins, Skp2 and cyclin-dependent kinase subunit 1 (Cks1), are
Yongrong Mao et al.
Oncology reports, 13(5), 837-846 (2005-04-06)
Thymidine kinase 1 (TK1) is a key enzyme involved in the synthesis of DNA precursors and thus, cell proliferation-dependent. Antibodies against TK1 have provided attractive tools for cancer diagnosis. Expression of TK1 in 158 non-small cell lung cancer (NSCLC) patients
Agnieszka Troszok et al.
Journal of fish diseases, 41(11), 1709-1718 (2018-08-26)
Cyprinid herpesvirus 3 (CyHV-3), also known as koi herpesvirus (KHV), is an aetiological agent of a virulent and lethal disease in common and koi carp. In this study, we examined in vitro the anti-CyHV-3 activity of acyclovir (ACV), nucleoside analogue commonly
T Morinaga et al.
Proceedings of the National Academy of Sciences of the United States of America, 80(15), 4604-4608 (1983-08-01)
DNA complementary to human alpha-fetoprotein (AFP)mRNA was cloned in the plasmid pBR322. Analysis of three overlapping cDNA clones revealed most of the nucleotide sequence of AFP mRNA, and the remaining nucleotides at the 5' end of the mRNA were elucidated
Y Saito et al.
Hepatology (Baltimore, Md.), 33(3), 561-568 (2001-03-07)
To evaluate the significance of alterations in DNA methylation during human hepatocarcinogenesis, we examined levels of mRNA for DNA methyltransferases and methyl-CpG-binding proteins and the DNA methylation status in 67 hepatocellular carcinomas (HCCs). The average level of mRNA for DNMT1
Annukka Paju et al.
European urology, 52(6), 1670-1679 (2007-02-20)
Tumor-associated-trypsin inhibitor (TATI) is frequently coexpressed with trypsinogen in tumors. Recently, we found expression of trypsinogens in prostate cancer. We have now studied whether TATI is also expressed in prostate cancer and if TATI expression is associated with Gleason grade
J S Ross et al.
Contact dermatitis, 29(2), 84-87 (1993-08-01)
A mix of 3 sesquiterpene lactones (SL) (SL mix 0.1%) was evaluated over a 4-year period. Of 7420 patients with eczema investigated by patch testing, 135 (68 male, 67 female) (1.8%) demonstrated positive reactions, 114 (84%) considered clinically relevant. Females
Babasaheb P Bandgar et al.
Bioorganic & medicinal chemistry, 18(5), 2060-2065 (2010-02-09)
A combinatorial library of beta-chlorovinyl chalcones (4) were synthesized by Claisen-Schmidt condensation reaction. Catalytic reaction of substituted 3-chloro-3-phenyl-propenal (2) and 1-(2,4-dimethoxy-phenyl)-ethanone or 1-(4-methoxy-phenyl)-ethanone (3) in alkaline conditions furnished the target compound 5-chloro-1-(2,4-dimethoxy-phenyl)-5-phenyl-penta-2,4-dien-1-one (4). The synthesized compounds were screened for their
Chang Hee Jung et al.
Clinical endocrinology, 77(5), 699-706 (2012-01-04)
The ratio of apolipoprotein B (apoB) to apolipoprotein A1 (apoA1) has been reported to be associated with the metabolic syndrome (MetS). However, the optimal cut-off value of apoB/A1 ratio for detecting subjects with MetS has remained undetermined. In the present
Su-Mei Lu et al.
Chinese medical journal, 124(10), 1483-1487 (2011-07-12)
Twist is a highly conserved epithelial-mesenchymal transcription factor that has been reported to be a key factor in tumor malignancy, including lymph node metastasis. It represents the major step of dissemination and serves as a chief prognostic indicator of disease
Stephanie Heim et al.
The American journal of surgical pathology, 38(1), 106-110 (2013-10-15)
Papillary tumors of the pineal region are rare glial tumors located in the vicinity of the third ventricle, the clinical behavior of which is often aggressive. Little is known about the prognostic markers that might aid to identify patients at
M Zhang et al.
FEBS letters, 373(3), 203-206 (1995-10-16)
An enzyme which converts D-dopachrome into 5,6-dihydroxyindole has recently been isolated from rat liver. Enzymatic D-dopachrome conversion has been observed in extracts from all tissues examined of several species, including man. We have now cloned and sequenced a 628 bp
Hasan Dursun et al.
Gene, 522(2), 192-195 (2013-04-11)
To investigate the association of endothelial nitric oxide synthase gene intron 4 (eNOS4) polymorphisms with nephrotic syndrome, the eNOS4 genotypes were assessed in 161 children with nephrotic syndrome in comparison with 78 healthy subjects. We classified the children with nephritic
Aneesa Noormohamed et al.
Foodborne pathogens and disease, 9(7), 617-624 (2012-05-02)
Campylobacter species are one of the leading causes of foodborne disease in the United States. Campylobacter jejuni and Campylobacter coli are the two main species that are of concern to human health, and they cause approximately 95% of human infections.
Michelle A Reed et al.
Organic & biomolecular chemistry, 1(3), 463-471 (2003-08-21)
While X-ray and NMR structures are now available for most components of the Type II fatty acid synthase (FAS), there are no structures for Type I FAS domains. A region from the mammalian (rat) FAS, including the putative acyl carrier
Najmeh Haseli et al.
Hepatitis monthly, 13(7), e10257-e10257 (2013-09-26)
Liver transplantation is considered as the standard treatment for both children and adults with end-stage liver diseases. Using this method, children who have no chance for life can live a much longer life .Shiraz Transplant Center is the major pediatric
U Kayabas et al.
Chemotherapy, 58(1), 34-43 (2012-02-22)
Cutaneous anthrax (CA) is the most common clinical presentation in human anthrax, but the duration of antibiotic therapy in naturally occurring CA is controversial. The aim of this study was to compare the clinical outcomes of patients receiving antibiotic treatment
1/4