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75-36-5
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关键词:'75-36-5'
显示 1-30 共 181 条结果 关于 "75-36-5" 范围 论文
Hong Wu et al.
Acta Cardiologica Sinica, 35(5), 524-533 (2019-10-02)
YiqiHuoxue decoction (YHD) is frequently prescribed to prevent and treat cardiovascular diseases. YHD inhibits platelet aggregation, however the underlying mechanisms are unclear. The in vitro and in vivo anti-platelet and antithrombotic effects of YHD and ethanol-precipitated YHD (EYHD) and underlying
Christos Haritoglou et al.
Retina (Philadelphia, Pa.), 26(6), 618-622 (2006-07-11)
To report on long-term results of macular hole surgery with peeling of the internal limiting membrane (ILM) in a prospective nonrandomized study. Sixty-four consecutive patients with a follow-up of at least 36 months were included. Only idiopathic macular holes were
Yan-Jie You et al.
Cancer letters, 315(2), 138-144 (2011-11-22)
Epigenetic inactivation of protein tyrosine phosphatase receptor-type O (PTPRO), a new member of the PTP family, has been described in several forms of cancer. We evaluated PTPRO promoter hypermethylation as a potential biomarker in esophageal squamous cell carcinoma (ESCC). This
Wissame El Bakkouri et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 33(4), 539-544 (2012-05-10)
To evaluate the perceptive and linguistic results in 2 predefined genetic population of children with implants. Retrospective cohort study. Otolaryngology department of a tertiary referral hospital. Among 336 children with prelingual deafness who underwent implantation in our department between 1997
Jin Wang et al.
Medical oncology (Northwood, London, England), 27(2), 219-223 (2009-03-18)
Expression of the Raf kinase inhibitor protein (RKIP), a metastasis suppressor, is high in normal tissues, low in primary cancers, and lowest or absent in metastatic cancers. Here, we studied the expression of RKIP in nonneoplastic gastric tissue and gastric
C J Winters et al.
The Journal of membrane biology, 177(3), 221-230 (2000-10-03)
We have isolated two new and highly homologous cDNAs, mmClC-Ka from mouse outer medulla and mcClC-Ka from mouse cortex. In both cases, mRNA was obtained from the indicated region and subjected to RT-PCR using primers from the nucleotide sequence of
Agnieszka K Witkiewicz et al.
Journal of the American College of Surgeons, 208(5), 781-787 (2009-05-30)
The recently discovered indoleamine 2,3-dioxygenase-2 (IDO2) gene has 2 functional polymorphisms that abolish its enzymatic activity. We hypothesize that expression of the IDO2 enzyme in primary pancreatic ductal adenocarcinomas (PDA) can help cancer cells evade immune detection. Because the IDO2
Karen R Kelly et al.
American journal of physiology. Endocrinology and metabolism, 296(6), E1269-E1274 (2009-04-09)
Aging and obesity are characterized by decreased beta-cell sensitivity and defects in the potentiation of nutrient-stimulated insulin secretion by GIP. Exercise and diet are known to improve glucose metabolism and the pancreatic insulin response to glucose, and this effect may
N Vijayalakshmi et al.
Oncology research, 16(11), 527-533 (2008-03-01)
Cervical cancer is the one of the most common cancers affecting the south Indian women. The objective of the present study was to analyze the pl6/Rb/cyclin D1 pathway in the normal (n=30), dysplastic (n=56), and malignant cervical epithelium (n=142) using
Sui Wang et al.
Drug metabolism and disposition: the biological fate of chemicals, 31(6), 773-775 (2003-05-21)
The purpose of the present study was to evaluate the effect of 1,7-phenanthroline (PH), which has been proposed to be a selective phase II enzyme inducer, on the gene expression of xenobiotic transporters, as well as hepatic and renal drug-metabolizing
Daniel T Oberlin et al.
Urology, 85(4), 814-818 (2015-03-31)
To compare how providers of testosterone replacement therapy (TRT) in large metropolitan cities promote androgen replacement on their patient-oriented Web sites. TRT provider Web sites were identified using Google search and the terms "Testosterone replacement" and the name of the
Skander Mulder et al.
Translational research : the journal of laboratory and clinical medicine, 222, 17-27 (2020-05-22)
The mineralocorticoid receptor antagonist spironolactone significantly reduces albuminuria in subjects with diabetic kidney disease, albeit with a large variability between individuals. Identifying novel biomarkers that predict response to therapy may help to tailor spironolactone therapy. We aimed to identify a
Azra Raza et al.
Cancer, 113(7), 1596-1604 (2008-08-23)
The treatment of myelodysplastic syndromes (MDS) remains a challenge to the clinician despite recent advances. Many patients will either not respond or will have only limited and/or brief responses to single-agent therapy. Eventually, 30% of patients with MDS will progress
Peter Fischer et al.
Dementia and geriatric cognitive disorders, 25(6), 501-507 (2008-05-01)
Few prospective community-based cohort studies have so far concentrated specifically on the risk factors for Alzheimer dementia (AD) with onset after the age of 75 years. We prospectively investigated a birth cohort of 585 nondemented inhabitants in the area on
M Inzinger et al.
The British journal of dermatology, 165(3), 640-645 (2011-05-14)
Few studies have directly compared the clinical efficacy of psoralen plus ultraviolet A (PUVA) vs. biologics in the treatment of psoriasis. To compare the clinical efficacy of PUVA and biologic therapies for psoriasis under daily life conditions. Data from a
Gonzalo Sapisochin et al.
Journal of hepatology, 67(1), 92-99 (2017-03-05)
There is limited information on the use of stereotactic body radiotherapy (SBRT) as a bridge to liver transplantation for hepatocellular carcinoma and no study comparing its efficacy to transarterial chemoembolization (TACE) and radiofrequency ablation (RFA). We aimed to ascertain the
Julijana Vuchkova et al.
American journal of physiology. Renal physiology, 307(5), F525-F532 (2014-07-06)
Albuminuria in nephrotic states is thought to arise from the formation of large pores in the glomerular capillary wall as large hydrodynamic probes, like Ficoll, have increased fractional clearance. In the present study, we tested for large pore formation in
Vaibhav Kumar Varshney et al.
Indian journal of cancer, 56(2), 135-143 (2019-05-08)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We analyzed the clinicopathological features, resectability, immunohistochemical markers, and various factors predictive of disease recurrence and survival. Retrospective analysis of prospectively maintained database of GIST patients
Frank Schönleben et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 12(12), 3851-3855 (2006-06-17)
Recent studies have reported high frequencies of somatic mutations in the phosphoinositide-3-kinase catalytic-alpha (PIK3CA) gene in various human solid tumors. More than 75% of those somatic mutations are clustered in the helical (exon 9) and kinase domains (exon 20). The
K A Elsaid et al.
Osteoarthritis and cartilage, 23(1), 114-121 (2014-09-16)
Study the impact of intra-articular interleukin-1 receptor antagonist (IL-1 ra) treatment on lubricin biosynthesis following anterior cruciate ligament transection (ACLT) in the rat and evaluate the effect of combined IL-1 ra and recombinant human lubricin (rhPRG4) treatments on chondrocyte apoptosis. ACLT
Raja R Seethala et al.
The American journal of surgical pathology, 34(8), 1106-1121 (2010-07-01)
The MECT1/MAML2 translocation is identified in a large proportion of mucoepidermoid carcinomas (MEC) of the salivary gland and is an emerging favorable prognosticator. However, there are conflicting data on this translocation's specificity, restriction to low/intermediate MEC, and strength as a
L D Carter-Dawson et al.
Investigative ophthalmology & visual science, 17(6), 489-498 (1978-06-01)
The retinas of rd/rd C57BL/6J-rd le mice have been examined by light and electron microscopy to determine whether rod cell degeneration precedes cone cell degeneration. In all regions of the eye, a rapid rod degeneration precedes a much slower cone
Ekaterina Doubrovina et al.
Blood, 120(8), 1633-1646 (2012-05-25)
The Wilms tumor protein (WT-1) is widely recognized as a tumor antigen that is expressed differentially by several malignancies. However, WT-1 peptides known to induce tumoricidal T cells are few. In the present study, we evaluated T-cell responses of 56
An Coosemans et al.
Gynecologic oncology, 111(3), 502-508 (2008-10-22)
Wilms' tumor gene (WT1), located on chromosome 11, encodes a transcription factor that contributes to the carcinogenesis of uterine sarcomas. To expand the knowledge on the biological role of WT1 in other uterine cancers, we focused on its detection in
Matthew R Smith et al.
Journal of Crohn's & colitis, 8(8), 890-897 (2014-02-11)
The role of mycophenolate mofetil (MMF) as an immunomodulatory drug in managing inflammatory bowel disease (IBD) is yet to be fully defined. We reviewed our experience of MMF in treating patients with IBD. Retrospective analysis was performed on all patients
Carolyn Y Ho et al.
Circulation, 105(25), 2992-2997 (2002-06-26)
Unexplained left ventricular hypertrophy (LVH) is considered diagnostic of hypertrophic cardiomyopathy (HCM) but fails to identify all genetically affected individuals. Altered diastolic function has been hypothesized to represent an earlier manifestation of HCM before the development of LVH; however, data
Roberta Ceci et al.
European journal of applied physiology, 115(3), 531-539 (2014-11-10)
Physical exercise is associated with enhanced production of reactive oxygen species, which if uncontrolled can result in tissue injury. Phosphodiesterase type 5 inhibitors (PDE5i) exhibit protective effect against oxidative stress, both in animals and healthy/unhealthy humans. However, the effect of
Thomas Dean et al.
Molecular endocrinology (Baltimore, Md.), 22(1), 156-166 (2007-09-18)
PTH and PTHrP use the same G protein-coupled receptor, the PTH/PTHrP receptor (PTHR), to mediate their distinct biological actions. The extent to which the mechanisms by which the two ligands bind to the PTHR differ is unclear. We examined this
Timothy J Poterucha et al.
Journal of drugs in dermatology : JDD, 12(3), 308-310 (2013-04-03)
Erythromelalgia is an uncommon neurovascular disorder characterized by redness, increased skin temperature, and pain that usually occurs in the extremities. Treatment remains challenging because of its varying response to medical therapy. The objective of this study was to assess the
R Izaguirre-Avila et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 8(2), 169-177 (2002-07-18)
Acetylsalicylic acid inhibits thromboxane A2 production and reduces the risk of vascular occlusive events by 20% to 25%. Ticlopidine inhibits ADP-dependent platelet aggregation and reduces the same risk by 30% to 35%, but produces some adverse effects. Clopidogrel is a
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