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P Palozza et al.
Current cancer drug targets, 12(6), 640-657 (2012-04-03)
Increasing evidence indicates that tomato lycopene may be an ideal candidate in protecting from cancer risk related to smoking exposure. The carotenoid shows potent redox-properties by which it decreases the reactive oxygen species (ROS) generated by smoke and modulates redox-sensitive
Paola Palozza et al.
Acta biochimica Polonica, 59(1), 21-25 (2012-03-20)
It has been suggested that lycopene, the major carotenoid found in tomato, exhibits health-beneficial effects by virtue of its antioxidant activity. However, recent literature suggests that lycopene can actually "perform" roles independent of such capacity and involving a direct modulation
Jian Xu et al.
Molecular and cellular probes, 46, 101419-101419 (2019-07-08)
This study aims to investigate the influences of lycopene on ovarian cancer cells SKOV3 in vitro and the corresponding mechanism. SKOV3 cultures were divided into four groups and treated with lycopene at 0 (the control group), 1 × 10-6, 1 × 10-5 and 1 × 10-4 mol/L
Sebastian Dams et al.
International journal of food sciences and nutrition, 71(6), 769-780 (2020-02-18)
The major aim of this controlled, randomised, open-labelled, parallel-grouped, clinical trial was to investigate whether supplementation with different dosages of omega-3 fatty acids (0.5 g/d and 1 g/d) from a plant-based fatty acid supplement affected omega-3-indices (O3I) in well-nourished, healthy people. In
P Palozza et al.
Annals of nutrition & metabolism, 61(2), 126-134 (2012-09-12)
Increased ingestion of tomato, containing lycopene, has been associated with a decreased risk for atherosclerosis, although the exact molecular mechanism is still unknown. Here we review the available evidence for a direct regulation of tomato lycopene on cholesterol metabolism using
Xiang-Dong Wang
The American journal of clinical nutrition, 96(5), 1214S-1222S (2012-10-12)
The beneficial effects of a high intake of tomatoes and tomato products on the risk of certain chronic diseases have been presented in many epidemiologic studies, with the suggestion that lycopene (a major carotenoid in tomatoes) is a micronutrient with
A Leyton et al.
Journal of applied microbiology, 127(4), 1069-1079 (2019-06-27)
To evaluate an aqueous extract of Macrocystis pyrifera as a nutrient source for the production of carotenoids by a marine Rhodotorula mucilaginosa isolated from seaweed samples. The effect of different culture conditions on the concentration of biomass and total pigments
David R Tennant et al.
The British journal of nutrition, 112(7), 1214-1225 (2014-08-12)
Fruit and vegetables make an important contribution to health, partly due to the composition of phytonutrients, such as carotenoids and polyphenols. The aim of the present study was to quantify the intake of fruit and vegetables across different European countries
Ying Wang et al.
The Journal of nutrition, 144(7), 1067-1074 (2014-04-20)
Hyperlipidemia and elevated circulating C-reactive protein (CRP) and total homocysteine (tHcy) concentrations are cardiovascular disease (CVD) risk factors. Previous studies indicated that higher serum carotenoid concentrations were inversely associated with some of these biomarkers. However, whether dietary carotenoid intake is
Marcel Fuciman et al.
The journal of physical chemistry. B, 119(4), 1457-1467 (2015-01-07)
Two carotenoids with aryl rings were studied by femtosecond transient absorption spectroscopy and theoretical computational methods, and the results were compared with those obtained from their nonaryl counterpart, β-carotene. Although isorenieratene has more conjugated C═C bonds than β-carotene, its effective
Nancy E Moran et al.
Archives of biochemistry and biophysics, 539(2), 171-180 (2013-07-13)
Intake of lycopene, a red, tetraterpene carotenoid found in tomatoes is epidemiologically associated with a decreased risk of chronic disease processes, and lycopene has demonstrated bioactivity in numerous in vitro and animal models. However, our understanding of absorption, tissue distribution
Jia-Kun Liu et al.
PloS one, 9(10), e110852-e110852 (2014-10-21)
The BioBricks standard has made the construction of DNA modules easier, quicker and cheaper. So far, over 100 BioBricks assembly schemes have been developed and many of them, including the original standard of BBF RFC 10, are now widely used.
April M Miguez et al.
Frontiers in microbiology, 9, 760-760 (2018-05-19)
Using cells as microbial factories enables highly specific production of chemicals with many advantages over chemical syntheses. A number of exciting new applications of this approach are in the area of precision metabolic engineering, which focuses on improving the specificity
Reyna María Cruz Bojórquez et al.
Nutricion hospitalaria, 28(1), 6-15 (2013-07-03)
Lycopene is a carotenoid, which is found mainly in tomatoes, retains its functional properties after processing, is not toxic and has antioxidant, anti-inflammatory and chemotherapeutics effects in cardiovascular or neurodegenerative diseases and in some cancers. However, it seems that its
Carolina Cortés-Herrera et al.
Molecules (Basel, Switzerland), 24(24) (2019-12-15)
Avocado (a fruit that represents a billion-dollar industry) has become a relevant crop in global trade. The benefits of eating avocados have also been thoroughly described as they contain important nutrients needed to ensure biological functions. For example, avocados contain
Jun Liu et al.
The British journal of nutrition, 112(12), 2041-2048 (2014-10-28)
The association between serum carotenoids and the metabolic syndrome (MetS) remains uncertain, and little is known about this relationship in the Chinese population. The present study examined the association between serum carotenoid concentrations and the MetS in Chinese adults. We
Ying Zou et al.
Fitoterapia, 99, 211-217 (2014-09-28)
Lycopene is a member of the carotenoid family and has strong anti-oxidant properties. Lycopene occurs in tomato-based food products primarily as an all-E isomer (80-97%),but its Z-isomers accounts for 79 to 88% of total lycopene in benign or malignant prostate
Mevlüt Şener Ural
Chemosphere, 90(7), 2059-2064 (2013-01-15)
The present study was carried out to investigate the potential ameliorative effects of lycopene against chlorpyrifos (CPF) toxicity in carp. The fish were divided into 7 different experimental groups and received the following treatments: Group 1, control; Group 2, orally
Qingqing Yin et al.
Neuropharmacology, 86, 389-396 (2014-08-12)
Fructose intake is linked with the increasing prevalence of insulin resistance, and insulin resistance links Alzheimer's disease with impaired insulin signaling, oxidative damage, neuroinflammation, and cognitive impairment. As a member of the carotenoid family of phytochemicals, lycopene is used as
Blanche C Ip et al.
Cancer prevention research (Philadelphia, Pa.), 7(12), 1219-1227 (2014-10-09)
Obesity is associated with increased liver cancer risks and mortality. We recently showed that apo-10'-lycopenoic acid, a lycopene metabolite generated by beta-carotene-9',10'-oxygenase (BCO2), inhibited carcinogen-initiated, high-fat diet (HFD)-promoted liver inflammation, and hepatic tumorigenesis development. The present investigation examined the outstanding
Jinyao Chen et al.
Journal of medicinal food, 16(5), 361-374 (2013-05-02)
Lycopene is a potentially useful compound for preventing and treating cardiovascular diseases and cancers. Studies on the effects of lycopene on oxidative stress offer insights into its mechanism of action and provide evidence-based rationale for its supplementation. In this analysis
Edward M Barbieri et al.
Cell, 171(6), 1453-1467 (2017-11-21)
We describe a multiplex genome engineering technology in Saccharomyces cerevisiae based on annealing synthetic oligonucleotides at the lagging strand of DNA replication. The mechanism is independent of Rad51-directed homologous recombination and avoids the creation of double-strand DNA breaks, enabling precise
Waheed Arshad et al.
PloS one, 9(5), e96979-e96979 (2014-05-13)
Tomato (Solanum lycopersicum L.) is the second most important cultivated crop next to potato, worldwide. Tomato serves as an important source of antioxidants in human diet. Alternaria solani and Fusarium oxysporum cause early blight and vascular wilt of tomato, respectively
M A Valero et al.
Nutricion hospitalaria, 26(6), 1236-1241 (2012-03-14)
lycopene is a carotene with a potent antioxidant effect found in tomato and its derivatives. Given that diabetic patients present an increased oxidative stress, lycopene could be beneficial. The aim of this scientific review has been to analyze the scientific
Seon Young Park et al.
Metabolic engineering, 49, 105-115 (2018-08-11)
Astaxanthin is a reddish keto-carotenoid classified as a xanthophyll found in various microbes and marine organisms. As a powerful antioxidant having up to 100 times more potency than other carotenoids such as β-carotene, lutein, and lycopene, astaxanthin is a versatile
Volker Böhm
Molecular nutrition & food research, 56(2), 296-303 (2012-03-16)
Cardiovascular diseases (CVDs) are the leading causes of human morbidity and mortality in developed countries. Specific biomarkers in this context are markers of inflammation, lipid status, thrombosis and oxidative stress. One recommendation for CVD prevention is to increase consumption of
Sol M Rivera et al.
Mass spectrometry reviews, 33(5), 353-372 (2013-11-02)
The present review compiles positive MS fragmentation data of selected carotenoids obtained using various ionization techniques and matrices. In addition, new experimental data from the analysis of carotenoids in transgenic maize and rice callus are provided. Several carotenes and oxygen-functionalized
Beibei Duan et al.
Nutrients, 11(9) (2019-09-06)
Thirty-four samples of human milk (HM) collected from mothers in Korea were classified into three groups according to their fat content. The lutein + zeaxanthin, β-cryptoxanthin, β-carotene, lycopene, α-carotene, and fatty acids (FAs) present in the HM were quantitatively analyzed.
Tali Silberstein et al.
Harefuah, 152(8), 461-463 (2013-10-31)
Prostate cancer is one of the most common types of cancer and it is the second most common cause of cancer-related death among men in the western world. Microscopic prostate cancer was found in up to 30% of men as
James Kilcrease et al.
Plant science : an international journal of experimental plant biology, 232, 57-66 (2015-01-27)
The fruits of Capsicum spp. are especially rich sites for carotenoid synthesis and accumulation, with cultivar-specific carotenoid accumulation profiles. Differences in chromoplast structure as well as carotenoid biosynthesis are correlated with distinct carotenoid accumulations and fruit color. In the present
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