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关键词:'76-54-0'
显示 1-30 共 31 条结果 关于 "76-54-0" 范围 论文
Shigeto Ueda et al.
Pancreas, 29(1), e1-e8 (2004-06-24)
Recent studies have shown that some growth factor receptors with tyrosine kinase activity, eg, the epidermal growth factor receptor (EGFr) and the c-erbB-2 (HER-2) oncoprotein, are associated with aggressive biologic behavior of various cancer cell types. We examined the clinicopathological
Jose M Rubio et al.
The lancet. Psychiatry, 7(9), 749-761 (2020-08-24)
Most individuals with schizophrenia-spectrum disorders have relapses, which increase the risk of morbidity and mortality. Because non-adherence to antipsychotic maintenance treatment could affect more than half of individuals with schizophrenia-spectrum disorders, psychosis relapse can often be confounded by unnoticed treatment
P G J ter Horst et al.
Journal of clinical pharmacy and therapeutics, 39(5), 541-544 (2014-07-06)
Depression during pregnancy is common and includes risks for mother and child. Pharmacokinetics of venlafaxine may be changed during pregnancy. This study aimed to describe changes in metabolic ratios and concentrations of venlafaxine and its main metabolite O-desmethylvenlafaxine during and
Rajeev S Bhide et al.
Molecular cancer therapeutics, 9(2), 369-378 (2010-01-28)
Tumor angiogenesis is a complex and tightly regulated network mediated by various proangiogenic factors. The fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) family of growth factors, and associated tyrosine kinase receptors have a major influence in tumor
Partha Sardar et al.
Circulation. Cardiovascular interventions, 12(1), e007244-e007244 (2019-01-05)
The objective of this study was to evaluate the evidence-base supporting the American Heart Association and American College of Cardiology guidelines on peripheral vascular interventions. American Heart Association/American College of Cardiology guideline documents available as of May 2018 were abstracted
Imen Nouioui et al.
Microorganisms, 8(10) (2020-10-07)
Strains 335427T and 234509T, isolated from two 76-year-old patients with chronic pulmonary diseases, were the subject of polyphasic taxonomic studies and comparative genomic analyses for virulence factors. The 16 rRNA gene sequence similarity between strains 335427T and 234509T and their
Ali Cihan Taskin et al.
In vitro cellular & developmental biology. Animal, 55(7), 473-481 (2019-06-20)
Leptin, a metabolic hormone, regulates the reproductive functions responding to both nutritional and body conditions. Embryonic stem cells play important roles in reproductive technology, but their derivation can be challenging. In this study, we evaluated the derivation rates of mouse
Christian Récher et al.
Lancet (London, England), 378(9806), 1858-1867 (2011-11-29)
The outcome of diffuse large B-cell lymphoma has been substantially improved by the addition of the anti-CD20 monoclonal antibody rituximab to chemotherapy regimens. We aimed to assess, in patients aged 18-59 years, the potential survival benefit provided by a dose-intensive
Ankur R Sangoi et al.
The American journal of surgical pathology, 35(5), 678-686 (2011-04-15)
The diagnosis of metastatic clear cell renal cell carcinoma (CC-RCC) can be difficult because of its morphologic heterogeneity and the increasing use of small image-guided biopsies that yield scant diagnostic material. This is further complicated by the degree of morphologic
Simon Greulich et al.
Journal of the American Heart Association, 8(12), e012429-e012429 (2019-06-12)
Background Acute complete occlusion of a coronary artery results in progressive ischemia, moving from the endocardium to the epicardium (ie, wavefront). Dependent on time to reperfusion and collateral flow, myocardial infarction ( MI ) will manifest, with transmural MI portending
Kieron Dunleavy et al.
Blood, 106(3), 795-802 (2005-02-19)
The occurrence of delayed neutropenia following rituximab is poorly defined and of unknown cause. We hypothesized it may be related to perturbations of stromal derived factor-1 (SDF-1) and granulocyte homeostasis. Late-onset neutropenia (LON) was investigated in 130 patients with untreated
Pavit Luthra et al.
The lancet. Gastroenterology & hepatology, 4(11), 831-844 (2019-09-03)
There are several drugs available for the treatment of chronic idiopathic constipation, but their relative efficacy is unclear because there have been no head-to-head randomised controlled trials. We did a network meta-analysis to compare the efficacy of these therapies in
Rodney D Franklin et al.
Obstetrics and gynecology, 101(3), 455-462 (2003-03-15)
To compare the efficacy of unfractionated heparin and low molecular weight heparin in the in vitro binding of antiphospholipid antibodies obtained from the sera of patients with recurrent pregnancy loss. Women with immunoglobulin (Ig) G antibodies to the phospholipids cardiolipin
Marija Radak-Perović et al.
Srpski arhiv za celokupno lekarstvo, 140(11-12), 717-721 (2013-01-29)
There are 12 recommendations for gout treatment, based on evidence and opinion of experts. To assess the quality of therapy in patients with gout analyzing adherence to four selected recommendations. Retrospective cross sectional study of 111 patients with gouty flare
Jae-Hyuk Lee et al.
The American journal of pathology, 161(2), 611-618 (2002-08-07)
Gastric cancer is common among the world, but genetic mechanisms of gastric carcinogenesis are not well understood. Gastric polypoid adenomas and flat dysplasias are regarded as precursor lesions. However, a detailed molecular study of these lesions has not been done
Miriam K Laufer et al.
PloS one, 7(8), e42284-e42284 (2012-08-23)
The predominance of chloroquine-susceptible falciparum malaria in Malawi more than a decade after chloroquine's withdrawal permits contemplation of re-introducing chloroquine for targeted uses. We aimed to compare the ability of different partner drugs to preserve chloroquine efficacy and prevent the
Fernando S Velayos et al.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 9(3), 329-335 (2005-03-08)
MLH1 promoter hypermethylation has been described as the primary mechanism for high-frequency microsatellite instability (MSI-H) in sporadic colorectal cancers (CRCs). The underlying molecular mechanism for microsatellite instability (MSI) in synchronous and metachronous CRCs is not well described. A total of
Alessio Imperiale et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 44(11), 1755-1760 (2003-11-07)
The value of (123)I-hippuran (OIH) renal sequential scintigraphy (RSS) in predicting the evolution of defects detected by (99m)Tc-dimercaptosuccinic acid (DMSA) scanning during a first episode of acute pyelonephritis (APN) was assessed. Fifty-eight children with APN underwent (99m)Tc-DMSA planar scanning and
Sarah E E Berry et al.
The American journal of clinical nutrition, 88(4), 922-929 (2008-10-10)
Plant cell walls are known to influence the rate and extent of lipid release from plant food tissues during digestion; however, the effect of cell wall structure on postprandial lipemia is unknown. The objective was to investigate the effects of
M Ersoz et al.
Cellular and molecular biology (Noisy-le-Grand, France), 63(7), 69-75 (2017-08-26)
The aim of this study was to investigate the anti-proliferative, apoptotic, cytotoxic, and anti-oxidant effects of extracts from the lichen Cladonia pocillumon human breast cancer cells (MCF-7), and to characterize the anti-microbial features.  MCF-7 cells were treated with methanolic C.
Olivier Aubert et al.
Transplantation, 97(9), 946-952 (2014-04-25)
This prospective monocentric study investigated the effect of corticosteroids plus bortezomib to reduce anti-HLA antibodies before renal transplantation. Included were 23 patients with stable immunization against HLA and awaiting a kidney transplant (KT). Treatment consisted of bortezomib (1.3 mg/m) plus
Tarek M Mekhail et al.
Urologic oncology, 21(6), 424-430 (2003-12-25)
Limited information is available on the correlation of telomerase activity and the clinical and pathological characteristics, in patients with renal cell carcinoma (RCC). Telomerase repeat amplification protocol (TRAP) was used to measure telomerase activity in frozen RCC specimens from partial/radical
Irene N Njuguna et al.
The lancet. HIV, 5(1), e12-e22 (2017-11-19)
Urgent antiretroviral therapy (ART) among hospitalised HIV-infected children might accelerate recovery or worsen outcomes associated with immune reconstitution. We aimed to compare urgent versus post-stabilisation ART among hospitalised HIV-infected children in Kenya. In this unmasked randomised controlled trial, we randomly
M C Chang et al.
British journal of pharmacology, 135(3), 619-630 (2002-02-09)
Hydroxychavicol (HC; 10 - 50 microM), a betel leaf component, was found to suppress the 2% H(2)O(2)-induced lucigenin chemiluminescence for 53 - 75%. HC (0.02 - 2 microM) was also able to trap superoxide radicals generated by a xanthine/xanthine oxidase
Robert Howard et al.
The Lancet. Neurology, 14(12), 1171-1181 (2015-10-31)
Findings from observational studies have suggested a delay in nursing home placement with dementia drug treatment, but findings from a previous randomised trial of patients with mild-to-moderate Alzheimer's disease showed no effect. We investigated the effects of continuation or discontinuation
Patrick Schöffski et al.
European journal of cancer (Oxford, England : 1990), 134, 62-74 (2020-05-30)
Gastrointestinal stromal tumour (GIST) is commonly treated with tyrosine kinase inhibitors (TKIs), but most patients ultimately develop secondary resistance. Cabozantinib, a multi-targeted TKI inhibitor, has activity in patient-derived GIST mouse xenograft models and can overcome compensatory MET signalling occurring on
Julio Rosenstock et al.
Diabetes care, 27(6), 1265-1270 (2004-05-27)
A randomized, parallel-group, open-label, multicenter 16-week clinical trial compared efficacy and safety of repaglinide monotherapy and nateglinide monotherapy in type 2 diabetic patients previously treated with diet and exercise. Enrolled patients (n = 150) had received treatment with diet and
Dhaval Bhanusali et al.
Journal of drugs in dermatology : JDD, 11(7), 852-856 (2012-07-11)
Tinea capitis periodically undergoes demographic shifts in causative dermatophyte and therapeutic response to oral anti-fungal therapy. To determine prevalent fungal species and response to standard antifungal therapy in inner-city children of color. An IRB-approved chart review of demographic, clinical, diagnostic
Catherine A Koss et al.
The lancet. HIV, 7(4), e249-e261 (2020-02-23)
Optimal strategies for pre-exposure prophylaxis (PrEP) engagement in generalised HIV epidemics are unknown. We aimed to assess PrEP uptake and engagement after population-level HIV testing and universal PrEP access to characterise gaps in the PrEP cascade in rural Kenya and
David Neal Franz et al.
The Lancet. Oncology, 15(13), 1513-1520 (2014-12-03)
In the EXIST-1 trial, initiated on Aug 10, 2009, more than 35% of patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis complex had at least 50% reduction in SEGA volume after 9·6 months of treatment with everolimus.
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