搜索范围
76607
应用筛选条件
关键词:'76607'
显示 1-30 #N/A 168 条结果 关于 "76607" 范围 论文
Xin Su et al.
Neurourology and urodynamics, 34(1), 92-97 (2013-10-24)
To determine time course of the bladder inhibitory response to unilateral or bilateral stimulation of the tibial nerve (TN) and spinal nerve (SN) as well as the interaction of stimulation at these two sites. In anesthetized female rats, a wire
M Hadi Saiepour et al.
Current biology : CB, 25(6), 713-721 (2015-03-11)
To ensure that neuronal networks function in a stable fashion, neurons receive balanced inhibitory and excitatory inputs. In various brain regions, this balance has been found to change temporarily during plasticity. Whether changes in inhibition have an instructive or permissive
Inês Carneiro et al.
British journal of pharmacology, 171(14), 3404-3419 (2014-04-05)
Despite the abundant expression of the UDP-sensitive P2Y6 receptor in urothelial cells and sub-urothelial myofibroblasts its role in the control of bladder function is not well understood. We compared the effects of UDP and of the selective P2Y6 receptor agonist
Wei Liu et al.
PloS one, 10(4), e0122366-e0122366 (2015-04-08)
Vasicine (VAS), a potential natural cholinesterase inhibitor, exhibited promising anticholinesterase activity in preclinical models and has been in development for treatment of Alzheimer's disease. This study systematically investigated the in vitro and in vivo metabolism of VAS in rat using
Kodai Ingawa et al.
PloS one, 9(4), e94853-e94853 (2014-04-18)
Several systematic reviews have reported that flow mediated dilatation (FMD) was significantly increased in subjects after ingestion of chocolate that contains flavan-3-ols; however, the mechanisms responsible for this effect are not clear. In this study, we evaluated the effects of
Christianne E Strang et al.
Journal of neurophysiology, 113(1), 203-217 (2014-10-10)
The purpose of this study was to evaluate the expression patterns of nicotinic and muscarinic ACh receptors (nAChRs and mAChRs, respectively) in relation to one another and to understand their effects on rabbit retinal ganglion cell response properties. Double-label immunohistochemistry
C A Maggi et al.
Experientia, 42(2), 109-114 (1986-02-15)
The suitability of urethane anesthesia for physiopharmacological investigations is reviewed. Total dose administered and route of administration are recognized as factors having a great influence on both resting parameters and biological responses to drugs. A peculiar characteristic of urethane is
J Schlatter et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 28(3), 205-211 (1990-03-01)
Ethyl carbamate is found in fermented foods: bread contains 3-15 ng/g, stone-fruit brandies 200-20,000 ng/g, and about one-third of table-wine samples analysed contained more than 10 ng/g. In animals, ethyl carbamate is degraded to CO2, H2O and NH3, with intermediate
M E Hueletl-Soto et al.
International journal of impotence research, 26(6), 205-212 (2014-05-03)
Chronic antidepressant treatment is associated with sexual side effects, particularly affecting the ejaculatory response. Bupropion (BP), an antidepressant inhibiting dopamine/noradrenaline reuptake, seems to have a low impact upon male sexual function. Ejaculation is regulated both at the brain and spinal
Chikkanna K Raghavendra et al.
Steroids, 94, 21-30 (2014-12-24)
Tender cluster beans (CBs; Cyamopsis tetragonoloba) are observed to possess anti-lithogenic potential in experimental mice. Formation of cholesterol gallstones in gallbladder is controlled by procrystallizing and anticrystallizing factors present in bile in addition to supersaturation of cholesterol. This study aimed
Natalia A Gonzaga et al.
Alcohol (Fayetteville, N.Y.), 49(1), 47-56 (2015-01-06)
We analyzed the effects of ethanol withdrawal on the vascular and systemic renin-angiotensin system (RAS) and vascular oxidative stress. Male Wistar rats were treated with ethanol 3-9% (v/v) for a period of 21 days. Ethanol withdrawal was induced by abrupt
Ajay Padsalgikar et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 103(1), 159-168 (2014-05-09)
Polyurethane biostability has been the subject of intense research since the failure of polyether polyurethane pacemaker leads in the 1980s. Accelerated in vitro testing has been used to isolate degradation mechanisms and predict clinical performance of biomaterials. However, validation that
Katie M Vance et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(2), 776-785 (2015-01-16)
Severe autonomic dysfunction, including the loss of control of the cardiovascular, respiratory, and gastrointestinal systems, is a common comorbidity of stroke and other bleeding head injuries. Previous studies suggest that this collapse of autonomic control may be caused by thrombin
On the versatility of urethane/urea bonds: reversibility, blocked isocyanate, and non-isocyanate polyurethane.
Etienne Delebecq et al.
Chemical reviews, 113(1), 80-118 (2012-10-23)
H H Lee et al.
Human & experimental toxicology, 33(11), 1121-1133 (2014-02-08)
When lidocaine is locally delivered into the inner ear, it rapidly paralyzes the peripheral vestibular afferent neurons and induces unilateral vestibular loss. The goals of this study were to explore the possibility of developing intratympanic injection (IT) of lidocaine as
Kun-Ze Lee et al.
Experimental neurology, 263, 314-324 (2014-12-03)
Repeated exposure to hypoxia can induce spinal neuroplasticity as well as respiratory and somatic motor recovery after spinal cord injury (SCI). The purpose of the present study was twofold: to define the capacity for a single bout of hypoxia to
Omar Z Ameer et al.
American journal of physiology. Heart and circulatory physiology, 307(2), H143-H151 (2014-05-20)
This study investigated the effects of hypertension on regional aortic biomechanical and structural properties in three rat models of vascular calcification: the hypertensive Lewis polycystic kidney (LPK; n = 13) model of chronic kidney disease, spontaneously hypertensive rats (SHRs; n
Zi-Qin Zhao et al.
Canadian journal of diabetes, 37(3), 156-168 (2013-09-28)
This study aims to investigate the effects of telmisartan, pioglitazone and metformin administration on the prevention of new-onset type 2 diabetes mellitus in pre-diabetes Otsuka Long-Evans Tokushima Fatty (OLETF) rats fed with a high-fat diet (HFD). OLETF rats 22 weeks
The anesthetic mechanism of urethane: the effects on neurotransmitter-gated ion channels
Hara, et al.
Anesthesia and Analgesia, 94, 313-318 (2002)
Yuka Terada et al.
Journal of neuroscience research, 93(2), 361-369 (2014-10-01)
Hydrogen sulfide (H(2)S), formed by multiple enzymes, including cystathionine-γ-lyase (CSE), targets Ca(v)3.2 T-type Ca(2+) channels (T channels) and transient receptor potential ankyrin-1 (TRPA1), facilitating somatic pain. Pancreatitis-related pain also appears to involve activation of T channels by H(2)S formed by
Yutaka Maeda et al.
The Journal of clinical investigation, 122(12), 4388-4400 (2012-11-13)
Mucinous adenocarcinoma of the lung is a subtype of highly invasive pulmonary tumors and is associated with decreased or absent expression of the transcription factor NK2 homeobox 1 (NKX2-1; also known as TTF-1). Here, we show that haploinsufficiency of Nkx2-1
Robert T R Huckstepp et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(3), 1052-1067 (2015-01-23)
Contiguous brain regions associated with a given behavior are increasingly being divided into subregions associated with distinct aspects of that behavior. Using recently developed neuronal hyperpolarizing technologies, we functionally dissect the parafacial region in the medulla, which contains key elements
Hany M El-Bassossy et al.
Journal of diabetes research, 2015, 178540-178540 (2015-03-19)
The aim of the current study was to evaluate the possible protective effect of allopurinol (Allo) on experimentally induced insulin resistance (IR) and vascular complications. Rats were divided into four groups: control, IR, allopurinol-treated IR (IR-Allo), and allopurinol-treated control (Allo).
Marta Cal et al.
Amino acids, 44(3), 1085-1091 (2012-12-20)
1-[(4-Methylphenyl)oxy]pyrrolidine-2,5-dione and 1-[(4-methylphenyl)oxy]piperidine-2,6-dione react in a Lossen-type reaction with primary alcohols in the presence of triethylamine to furnish corresponding N(α)-urethane-protected β-alanine and γ-aminopropionic acid (GABA), respectively, with excellent yields and purities, in an essentially "one-pot" procedure.
Cezary Jan Treda et al.
Carcinogenesis, 35(4), 896-904 (2013-11-28)
Secretory leukocyte protease inhibitor (SLPI), 11.7 kDa serine protease inhibitor, is produced primarily in the respiratory tract, but it is often elevated in lung, head/neck and ovarian cancers. SLPI expression in relation to cancer progression, metastasis and invasion has been
Zhaohui Li et al.
Chinese medical journal, 127(19), 3464-3470 (2014-10-02)
Diabetes-related pathogenic factors can cause retinal ganglion cell (RGC) apoptosis, but the specific mechanism is not very clear. The aim of this study is to investigate the correlation between glycogen synthase kinase-3 (GSK-3) activation and retinal neuron apoptosis. In an
M Vivas et al.
The Journal of antimicrobial chemotherapy, 69(11), 3020-3026 (2014-06-26)
To determine the efficacy of daptomycin for the treatment of penicillin- and cephalosporin-resistant pneumococcal meningitis using in vitro and in vivo methods. In vitro killing curves were determined with clinically achievable CSF antibiotic concentrations. In a rabbit model of pneumococcal
Toshiya Ueno et al.
Anticancer research, 32(11), 4773-4780 (2012-11-17)
Lung cancer is the leading cause of cancer-related death worldwide. We previously reported that respiration-gated X-ray micro-computed tomography (micro-CT) is a useful tool for analyzing lung tumor development in animal models. Lung tumors were induced by a single intraperitoneal injection
Chiao-Jung Kao et al.
Cancer immunology research, 2(6), 581-589 (2014-06-05)
The goals of the present study were to define the effects of simultaneous cisplatin/tecemotide therapy on tumor development in a human mucin 1 (MUC1) transgenic lung cancer mouse model and to examine the effects of radiotherapy (RTX) on splenocytes, serum
Yi Zhang et al.
Biomaterials, 34(16), 4048-4056 (2013-03-08)
The field of tissue engineering and drug delivery calls for new measurement tools, non-invasive real-time assays, and design methods for the next wave of innovations. Based on our recent progress in developing intrinsically biodegradable photoluminescent polymers (BPLPs) without conjugating organic
1/6