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显示 1-30 共 51 条结果 关于 "78-39-7" 范围 论文
Meera Mahalingam et al.
The American Journal of dermatopathology, 32(8), 774-779 (2010-08-12)
The overlap in histopathologic features and immunoprofile of eccrine and apocrine neoplasms confounds basic issues relating to lineage of these entities. We evaluated expression of follicular stem-cell markers, cytokeratin (CK) 15 and nestin, in 78 benign and 23 malignant adnexal
Nusrat Homaira et al.
Journal of medical virology, 94(2), 782-786 (2021-10-12)
Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infection hospitalisations in Aboriginal infants specifically those aged <6 months. Maternally derived RSV antibody (Ab) can protect against severe RSV disease in infancy. However, the efficiency of transplacental
Guoqiang Xing et al.
Neuroscience letters, 454(1), 38-42 (2009-05-12)
Dysregulated brain glucose metabolism and lactate accumulation are seen following traumatic brain injury (TBI). The underlying molecular mechanism is poorly understood. Pyruvate dehydrogenase (PDH), the rate-limiting enzyme coupling cytosolic glycolysis to mitochondrial citric acid cycle, plays a critical role in
Koji Tanaka et al.
International journal of stroke : official journal of the International Stroke Society, 9(8), 1045-1051 (2014-03-14)
Atrial fibrillation impairs left atrial appendage function and the thrombus formation in the left atrial appendage is a major cause of cardioembolic stroke. To evaluate the association between the volume of the left atrial appendage measured by real-time three-dimensional transesophageal
Giuseppe Rovere et al.
Investigative ophthalmology & visual science, 57(15), 6652-6661 (2016-12-09)
To analyze the responses of different retinal ganglion cell (RGC) types to acute ocular hypertension (AOH) and intravitreal administration of brain-derived neurotrophic factor (BDNF). In adult albino rats, the anterior chamber of the left eye was cannulated with a needle
Masato Watanabe et al.
The Journal of infection, 70(5), 474-482 (2015-02-24)
Community-acquired pneumonia (CAP) is associated with high mortality when initial treatment fails. Early identification of these patients allows physicians to modify treatments earlier, increasing survival. Ninety-one hospitalized patients with CAP were studied. Serum soluble ST2 levels were measured at diagnosis
Johannes Zschocke et al.
Human mutation, 21(4), 399-399 (2003-03-26)
We present the results of a comprehensive analysis of mutations, polymorphisms and haplotypes in the phenylalanine hydroxylase (PAH) gene in 39 Croatian families with phenylketonuria (PKU). A total of 21 disease-causing mutations was identified on 78 out of 79 independent
A Parneix-Spake et al.
The Journal of dermatological treatment, 12(4), 191-197 (2002-09-21)
The emollient base of a topical corticosteroid, through its moisturizing properties, can be a useful treatment adjunct. To compare the healing properties of Eumovate trade mark (clobetasone butyrate) 0.05% cream with its emollient base, hydrocortisone 1% cream and with no
H Kawai et al.
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 68(11), 1324-1329 (1994-11-01)
Although erythromycin estolate has been fully assessed for pertussis treatment, the evaluation of erythromycin ethylsuccinate and stearate, the main erythromycin preparations used in Japan and the US, is inadequate. We evaluated these preparations to establish an appropriate treatment for pertussis
Goro Sasaki et al.
The Journal of clinical endocrinology and metabolism, 88(7), 3431-3436 (2003-07-05)
The 5alpha-reductase-2 encoded by the SRD5A2 gene plays a critical role in male sex differentiation by converting testosterone into 5alpha dihydrotestosterone in the peripheral target tissues. In this study, we examined the SRD5A2 gene in 81 Japanese patients with micropenis
Wayne L Furman et al.
Investigational new drugs, 30(4), 1660-1670 (2011-07-29)
Gefitinib potently inhibits neuroblastoma proliferation in vitro, and the gefitinib/irinotecan combination shows greater than additive activity against neuroblastoma xenografts. This Phase II pilot study estimated the rate of response to two courses of intravenous irinotecan plus oral gefitinib in children
Scott R Solomon et al.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 21(7), 1299-1307 (2015-03-24)
We enrolled 30 patients on a prospective phase II trial utilizing a total body irradiation (TBI)-based myeloablative preparative regimen (fludarabine 30 mg/m2/day × 3 days and TBI 150 cGy twice per day on day -4 to -1 [total dose 1200
S Testi et al.
Journal of the neurological sciences, 319(1-2), 37-41 (2012-06-06)
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), the most common form of familial vascular dementia, is caused by mutations of the NOTCH3 gene. Approximately two hundred pathogenic mutations have been reported within five exons (exons 3, 4
Gyan K Kayastha et al.
British journal of haematology, 177(6), 991-999 (2017-04-04)
The Glivec International Patient Assistance Programme makes Glivec (Imatinib mesylate) available to Philadelphia chromosome/BCR-ABL1 positive patients with chronic myeloid leukaemia (CML) in Lower and Middle Income Countries (LMIC). We have established a large cohort of 211 CML patients who are
Mark A Slabaugh et al.
American journal of ophthalmology, 153(5), 932-938 (2012-01-24)
To evaluate the clinical effect of topical difluprednate in pediatric patients for treatment of noninfectious uveitis. Retrospective, observational case series. Twenty-six eyes of 14 pediatric patients with noninfectious uveitis who were treated with topical difluprednate were evaluated. Anterior and posterior
Young Suk Kim et al.
International journal of radiation oncology, biology, physics, 84(3), 661-667 (2012-03-15)
Recently, cells deficient in O(6)-methylguanine-DNA methyltransferase (MGMT) were found to show increased sensitivity to temozolomide (TMZ). We evaluated whether hypermethylation of MGMT was associated with survival in patients with glioblastoma multiforme (GBM). We retrospectively analyzed 93 patients with histologically confirmed
Takahiro Kawakami et al.
Human molecular genetics, 15(6), 821-830 (2006-01-28)
A common deletion at chromosomal arm 14q32 in human renal cell carcinoma (RCC) prompted us to explore a tumor suppressor gene (TSG) in this region. We report that imprinted DLK1 at 14q32, a regulator of adipocyte differentiation, is a candidate
G Juyal et al.
Alimentary pharmacology & therapeutics, 26(10), 1325-1332 (2007-09-26)
Three common disease susceptibility variants in the NOD2 gene are associated with inflammatory bowel disease in Caucasians, but not in Asians. Aim To screen for NOD2 variants and examine susceptibility for inflammatory bowel disease in North Indians. A case-control study
Yisong Wang et al.
Scientific reports, 4, 7336-7336 (2014-12-09)
Genetic alterations and etiology of thymic epithelial tumors (TETs) are largely unknown, hampering the development of effective targeted therapies for patients with TETs. Here TETs of advanced-stage patients enrolled in a clinical trial of molecularly-guided targeted therapies were employed for
Takahiro Kawakami et al.
Human molecular genetics, 15(6), 821-830 (2006-01-28)
A common deletion at chromosomal arm 14q32 in human renal cell carcinoma (RCC) prompted us to explore a tumor suppressor gene (TSG) in this region. We report that imprinted DLK1 at 14q32, a regulator of adipocyte differentiation, is a candidate
Jing Zhao et al.
Zhonghua bing li xue za zhi = Chinese journal of pathology, 40(10), 671-674 (2012-02-11)
To investigate the detection technology and its clinical significance of the EGFR gene mutation in non-small cell lung cancer. DNA direct sequencing methods by PCR amplification were used to detect EGFR gene exons 18-21 mutation and to analyze its clinical
Cuizhen Li et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(12), 1263-1268 (2007-09-22)
Insulin-like growth factor-II mRNA-binding protein 3 (IMP3) is a newly identified oncofetal mRNA-binding protein that is involved in embryogenesis and carcinogenesis of some malignant neoplasms. To investigate the diagnostic and clinicopathologic significance of this protein in endometrial carcinomas, we evaluated
Takeshi Yabana et al.
Experimental eye research, 202, 108297-108297 (2020-10-13)
The genetically encoded green fluorescent protein-based calcium sensor, GCaMP, has been used to detect calcium transients and report neuronal activity. We evaluated the specificity of GCaMP3 expression to retinal ganglion cells (RGCs) of the transgenic Thy1-GCaMP3 mouse line in healthy
Carol L Shields et al.
Cornea, 34(1), 42-48 (2014-10-25)
To describe the clinical features, treatment, and outcome of patients with iris metastasis. Retrospective case series of 160 tumors in 107 eyes of 104 patients with iris metastasis from systemic cancer. The median age at presentation with iris metastasis was
Rachel E Harris et al.
Journal of Crohn's & colitis, 14(5), 608-616 (2020-01-01)
Increased risk of opportunistic infection-e.g., varicella zoster infection-secondary to therapies is a cause of morbidity in inflammatory bowel disease [IBD] patients. The UK vaccination schedule does not include varicella immunisation. We aimed to evaluate the varicella screening and immunisation programme
Karin Oechsle et al.
BMC palliative care, 18(1), 102-102 (2019-11-20)
This study prospectively evaluated distress, depressive and anxiety symptoms as well as associated factors in family caregivers (FC) of advanced cancer patients at initiation of specialist inpatient palliative care. Within 72 h after the patient's first admission, FCs were asked to
Kun Qian et al.
Public health nutrition, 23(14), 2485-2493 (2020-06-11)
To determine which set of BMI cut-offs is the most appropriate to define child and adolescent obesity in urban China. A cross-sectional study was carried out between 1 November and 31 December in 2017. Community Healthcare Center in Minhang District
Johanna Lähteenvuo et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 28(7), 1731-1740 (2020-04-04)
VEGF-B gene therapy is a promising proangiogenic treatment for ischemic heart disease, but, unexpectedly, we found that high doses of VEGF-B promote ventricular arrhythmias (VAs). VEGF-B knockout, alpha myosin heavy-chain promoter (αMHC)-VEGF-B transgenic mice, and pigs transduced intramyocardially with adenoviral
Giovanni Musso et al.
Hepatology (Baltimore, Md.), 49(2), 426-435 (2008-12-24)
Genetic factors underlying the association of NAFLD with diabetes and atherosclerosis are unknown. Recent human studies suggest transcription factor 7-like 2 (TCF7L2) polymorphism predisposes to diabetes through modulation of beta-cell function and modulates lipid levels in familial dyslipidemia. Emerging experimental
Paola E Leone et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(19), 6033-6041 (2008-10-03)
Deletions of chromosome 1 have been described in 7% to 40% of cases of myeloma with inconsistent clinical consequences. CDKN2C at 1p32.3 has been identified in myeloma cell lines as the potential target of the deletion. We tested the clinical
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