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显示 1-30 共 522 条结果 关于 "79617" 范围 论文
Carolina Santezi et al.
The journal of contemporary dental practice, 13(5), 735-739 (2012-12-20)
It is becoming more common for patients to look for cosmetic procedures in dental offices. The search for lost or desired esthetics by patients is increasingly frequent and the professional must be able to meet this demand. To do this
Jenna L Terebetski et al.
AAPS PharmSciTech, 15(5), 1334-1344 (2014-06-13)
To maximize the pharmacological effect of a pain reliever such as ibuprofen, early onset of action is critical. Unfortunately, the acidic nature of ibuprofen minimizes the amount of drug that can be solubilized under gastric conditions and would be available
Yu He et al.
Drug and chemical toxicology, 38(2), 145-151 (2014-05-23)
Tripterygium wilfordii Hook. f. (TW) is a traditional herbal medicine which has been widely used for the treatment of rheumatoid arthritis and other autoimmune diseases. However, adverse reactions of TW such as hepatotoxicity and nephrotoxicity have been frequently reported in
Hassan M Albishri et al.
Journal of chromatographic science, 53(7), 1123-1130 (2014-12-30)
Two cyclodextrin micellar liquid chromatographic methods were developed and applied to the simultaneous determination of bisoprolol/hydrochlorothiazide and atenolol/chlorthalidone combinations in urine matrices without sample pretreatment. These combined β-blockers and diuretics chemotherapies are commonly used in the treatment of hypertension and
Hande Kemaloglu et al.
Dental materials journal, 34(5), 618-622 (2015-10-07)
The aim was to evaluate the effects of fiber-reinforced composite restorations and a bulk-fill resin composite on the fracture strength of mandibular premolars treated endodontically. Standard mesio-occluso-distal (MOD) cavities were prepared in 48 mandibular premolars. Following root canal treatment, teeth
Wenfa Lu et al.
Journal of parasitology research, 2011, 316067-316067 (2011-05-18)
Wild-type (WT) C57BL/6 mice infected intraperitoneally with 5 × 10(6) Trypanosoma congolense survive for more than 30 days. C57BL/6 mice deficient in inducible nitric oxide synthase (iNOS(-/-)) and infected with 10(3) or 5 × 10(6) parasites do not control the
Fan-Zhi Kong et al.
Journal of chromatography. A, 1422, 318-324 (2015-10-27)
The traditional recycling free-flow isoelectric focusing (RFFIEF) suffered from complex structure, tedious operations and poor extensibility as well as high cost. To address these issues, a novel reciprocating free-flow isoelectric focusing device (ReFFIEF) was developed for proteins or peptides pre-fractionation.
Yu-Min He et al.
Journal of natural medicines, 69(3), 366-374 (2015-04-22)
The root of Gentiana crassicaulis has been widely used for the treatment of rheumatism, arthralgia, apoplexy, jaundice and diabetes in traditional medicines, and contains secoiridoid glycosides as the main active ingredients. In the present study, five new secoiridoid glycosides, 6'-O-β-D-xylopyranosylgentiopicroside
Sha Wu et al.
Die Pharmazie, 70(10), 640-645 (2015-11-26)
This study aimed to monitor liquid-liquid extraction of Gardenia jasminoides Ellis (Zhizi in Chinese) using in-line near-infrared spectroscopy. Shanzhiside (SZS), deacetyl asperulosidic acid methyl ester (DAAME), genipin-1-β-D-gentiobioside (GG), geniposide (GS), total acids (TA) and soluble solid content (SSC) were selected
Laura Mews et al.
The Angle orthodontist, 85(4), 645-650 (2014-08-27)
To examine differences in the shear bond strength of orthodontic brackets on differently mineralized enamel surfaces after applying a caries infiltrant or conventional adhesive. A total of 320 bovine incisors were assigned to eight pretreated groups, and the shear force
Olumuyiwa N Adedeji et al.
Antimicrobial agents and chemotherapy, 59(9), 5114-5122 (2015-04-22)
Artemisinin-based combination therapies (ACTs) have been adopted by most African countries, including Nigeria, as first-line treatments for uncomplicated falciparum malaria. Fixed-dose combinations of these ACTs, amodiaquine-artesunate (FDC AQAS) and artemether-lumefantrine (AL), were introduced in Nigeria to improve compliance and achieve
Marija Stojanović et al.
Biotechnology and applied biochemistry, 62(4), 458-466 (2014-09-17)
Fatty acid (FA) ascorbyl esters are recently emerging food, cosmetic, and pharmaceutical additives, which can be prepared in an eco-friendly way by using lipases as catalysts. Because they are amphiphilic molecules, which possess high free radical scavenging capacity, they can
Amirah Al-Attas et al.
Biomedical chromatography : BMC, 29(12), 1811-1818 (2015-06-11)
A green, novel, rapid, accurate and reliable capillary zone electrophoresis method was developed and validated for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical preparations. Separation was carried out using fused silica capillary (50 µm i.d. × 48.6 cm and 40.2 cm detection
Juliana Bidone et al.
BioMed research international, 2015, 238010-238010 (2015-06-24)
This study investigated the inhibitory effects of Achyrocline satureioides extract (ASE) incorporated into a topical nanoemulsion on Herpes Simplex Virus type 1 (HSV-1/KOS strain) replication, as well as the distribution of the main ASE flavonoids (quercetin, luteolin, and 3-O-methylquercetin) in
Sruthi Purushothaman et al.
Journal of proteomics, 112, 113-124 (2014-09-03)
The extensive arm regeneration of brittle stars following amputation is becoming increasingly recognized as a model system for understanding cellular differentiation and regeneration in a whole animal context. In this study we have used the emerging brittle star model Amphiura
Shuichi Suzuki et al.
Journal of medical virology, 87(11), 1853-1859 (2015-05-12)
Vaccine modified measles (VMM) affects individuals with attenuated vaccine induced immunity. An outbreak of measles occurred in a junior high school, starting from an unvaccinated eighth-grade student who developed natural measles and affected a majority of students who were immunized
Byul G Kim et al.
Biochemistry, 54(22), 3420-3430 (2015-05-20)
In an atmosphere of potassium ions, a modified c-MYC NHE III1 sequence with two G-to-T mutations (MYC22-G14T/G23T) forms a highly stable parallel-stranded G-quadruplex. The G-quadruplex exhibits a steady increase in its melting temperature, T(M), with an increase in the concentration
Kun Peng et al.
The AAPS journal, 16(4), 625-633 (2014-04-23)
Data generated using various immunoassay methods are an integral part of the development of protein therapeutics. These assays are used in clinical and preclinical studies to establish the pharmacokinetic (PK) and pharmacodynamic (PD) characteristics as well as to assess the
Jack L Ferracane et al.
The journal of adhesive dentistry, 15(5), 407-412 (2013-04-06)
To evaluate the potential for phosphoric acid solutions - common constituents of dental adhesive systems - of varying pH to solubilize dentin matrix components (DMCs) from human dentin. Human dentin chips were ground under liquid nitrogen to a powder (ca
Bo Tian et al.
Journal of materials science. Materials in medicine, 25(9), 2059-2068 (2014-05-27)
In order to improve the biocompatibility of metallic implants, bioactive components are often used as coatings so that a real bond with the surrounding bone tissue can be formed. We prepared ethyl cellulose/carbonated hydroxyapatite composite coatings (ECHCs) on Ti6Al4V substrates
Jiyoung A Hong et al.
Journal of medicinal chemistry, 52(17), 5485-5495 (2009-08-15)
Mycobacterium tuberculosis adenosine-5'-phosphosulfate (APS) reductase is an iron-sulfur protein and a validated target to develop new antitubercular agents, particularly for the treatment of latent infection. To facilitate the development of potent and specific inhibitors of APS reductase, we have probed
Khai Tuck Lee et al.
Analytical chemistry, 86(20), 10474-10483 (2014-09-19)
Herein we demonstrate the use of a wearable device that can selectively capture two distinct circulating protein biomarkers (recombinant P. falciparum rPfHRP2 and total IgG) from the intradermal fluid of live mice in situ, for subsequent detection in vitro. The
Yun Jeong Kim et al.
PloS one, 10(4), e0120840-e0120840 (2015-04-09)
Botulinum neurotoxin type A (BoNT/A) is the most potent protein toxin and causes fatal flaccid muscle paralysis by blocking neurotransmission. Application of BoNT/A has been extended to the fields of therapeutics and biodefense. Nevertheless, the global response of host immune
Ashani Samaratunga et al.
Applied biochemistry and biotechnology, 176(4), 1114-1130 (2015-05-04)
Production costs of cellulosic biofuels can be lowered if cellulases are recovered and reused using particulate carriers that can be extracted after biomass hydrolysis. Such enzyme recovery was recently demonstrated using enzymogel nanoparticles with grafted polymer brushes loaded with cellulases.
Wei Xie et al.
Nature communications, 6, 7570-7570 (2015-07-04)
Noble metals are important photocatalysts due to their ability to convert light into chemical energy. Hot electrons, generated via the non-radiative decay of localized surface plasmons, can be transferred to reactants on the metal surface. Unfortunately, the number of hot
Mahmoud N Taha et al.
Journal of chromatography. A, 1394, 137-147 (2015-04-08)
Extraction parameters, chemical fingerprint, and the single compounds' activity levels were considered for the selection of active botanicals. For an initial survey, the total bioactivity (i.e., total reducing capacity, total flavonoids contents and free radical scavenging capacity) of 21 aqueous
Eleonora Dellera et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 88(3), 643-650 (2014-08-17)
In the treatment of chronic wounds, topical application of anti-infective drugs such as silver sulfadiazine (AgSD) is of primary importance to avoid infections and accelerate wound repair. AgSD is used in burns and chronic wounds for its wide antibacterial spectrum
Harshavardhan V Pawar et al.
Journal of pharmaceutical sciences, 103(6), 1720-1733 (2014-04-05)
Wafers combining weight ratios of Polyox with carrageenan (75/25) or sodium alginate (50/50) containing streptomycin and diclofenac were prepared to improve chronic wound healing. Gels were freeze-dried using a lyophilisation cycle incorporating an annealing step. Wafers were characterised for morphology
Ondrej Cerny et al.
Journal of immunology (Baltimore, Md. : 1950), 194(10), 4901-4913 (2015-04-17)
The adenylate cyclase toxin-hemolysin (CyaA) plays a key role in the virulence of Bordetella pertussis. CyaA penetrates complement receptor 3-expressing phagocytes and catalyzes uncontrolled conversion of cytosolic ATP to the key second messenger molecule cAMP. This paralyzes the capacity of
Kristina Nelson et al.
Food chemistry, 194, 495-502 (2015-10-17)
Metabolic dysfunction in obesity may be attenuated by whole-grain intake, which has been attributed to synergistic actions of bioactive compounds. Germination/malting may increase grain bioactives, including polyphenols, however biological effects compared with non-germinated grains are unclear. Polyphenols and biological effects
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