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关键词:'80-17-1'
显示 1-30 共 613 条结果 关于 "80-17-1" 范围 论文
A Cianciulli et al.
Cancer genetics and cytogenetics, 151(1), 52-59 (2004-05-04)
Among chromosome defects in colon cancer, deletions in 1p, 17p, and 18q have been reported as frequent events. To verify this, we investigated 1p, 17p, and 18q aneusomy in 60 colorectal cancers and their surrounding mucosa by means of fluorescence
Milan Fiala et al.
Journal of neuroinflammation, 7, 76-76 (2010-11-11)
The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available. We used enzyme-linked immunosorbent assays (ELISAs) to measure the
Milan Fiala et al.
Journal of neuroinflammation, 7, 76-76 (2010-11-11)
The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available. We used enzyme-linked immunosorbent assays (ELISAs) to measure the
A Notarnicola et al.
Scandinavian journal of rheumatology, 44(3), 224-228 (2014-11-08)
To assess the serum levels of interleukin (IL)-15 and IL-17 in patients with idiopathic inflammatory myopathies (IIM) and correlate them with levels of IL-1 receptor antagonist (IL-1ra), IL-6, IL-10, interferon (IFN)-γ, monocyte chemoattractant protein (MCP)-1, macrophage inflammatory protein (MIP)-1α, and
Maria Cristina Honorati et al.
Osteoarthritis and cartilage, 12(9), 683-691 (2004-08-25)
To verify the involvement of proinflammatory cytokines IL-17, IL-1beta and tumor necrosis factor alpha (TNF-alpha) in cartilage vascularization by stimulating the production of vascular endothelial growth factor (VEGF) by chondrocytes isolated from patients with osteoarthritis (OA), in comparison with patients
Agnieszka M Rygiel et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17(6), 1380-1385 (2008-06-19)
The progression of Barrett's esophagus to esophageal adenocarcinoma is often characterized by the accumulation of genetic abnormalities. The goal was to evaluate the copy number alterations of several oncogene loci, including 7p12 [epidermal growth factor receptor (EGFR)], 8q24 (c-myc), and
Adrianna Szponar et al.
Histopathology, 58(6), 934-943 (2011-03-29)
Papillary renal cell tumours (RCT) are characterized by specific trisomies. The aim of this study was to identify small regions of duplication marking putative tumour genes. Full-tiling path bacterial artificial chromosome (BAC) array hybridization of 20 papillary RCTs confirmed the
M F Evans et al.
The Journal of pathology, 189(1), 53-59 (1999-08-19)
The clinical behaviour of ovarian tumours of low malignant potential (LMP) is unpredictable and it has been suggested that the majority of these lesions have no invasive potential. This study has analysed 92 epithelial ovarian tumours [11 mucinous cystadenomas, 18
Kendall C Shibuya et al.
PloS one, 9(5), e96565-e96565 (2014-05-06)
The immune response to pancreatic ductal adenocarcinoma (PDA) may play a role in defining its uniquely aggressive biology; therefore, we sought to clearly define the adaptive immune infiltrate in PDA. We used immunohistochemistry and flow cytometry to characterize the immune
D Saadoun et al.
Arthritis & rheumatology (Hoboken, N.J.), 67(5), 1353-1360 (2015-01-22)
Takayasu arteritis (TAK) is a large-vessel vasculitis that induces damage to the aorta and its branches. Glucocorticoids remain the gold standard of therapy for TAK. The nature of the T cells driving vascular inflammation and the effects of glucocorticoids on
Ping Chen et al.
Journal of immunology research, 2015, 416123-416123 (2015-05-23)
T helper- (Th-) cell immunodeficiency plays important roles in tumor development and their effects in chronic myeloid leukemia (CML) remain unclear. In the present study, we mainly investigated the role of Th22, Th17, and Th1 cell and their related cytokines
Nathalie Amiable et al.
Bone, 44(6), 1143-1150 (2009-03-07)
In osteoarthritis (OA), the subchondral bone undergoes a remodelling process involving several factors synthesized by osteoblasts. In this study, we investigated the expression, production, modulation, and role of PAR-2 in human OA subchondral bone osteoblasts. PAR-2 expression and production were
Chien-Yu Lin et al.
Anticancer research, 32(2), 475-482 (2012-01-31)
Breast cancer is the most common cancer in women. In recent years, mounting evidence has identified the possibility that 2q35, 3p24, 17q23 and fibroblast growth factor receptor 2 (FGFR2) may be genetic susceptibility loci for breast cancer. This study aimed
Min Wang et al.
Oncotarget, 6(20), 17958-17967 (2015-08-11)
T helper (Th) cell imbalance plays important roles in tumor development and their effects in Multiple myeloma (MM) remain unclear. In the present study, we investigated the levels and clinical significance of Th22, Th17 and Th1 cells in patients with
Lorenzo Falchi et al.
Cancer, 119(17), 3177-3185 (2013-09-12)
Little is known regarding racial disparities in characteristics and outcomes among patients with chronic lymphocytic leukemia (CLL). The characteristics and outcomes of untreated African American (AA) patients with CLL (n = 84) were analyzed and compared with a reference nonblack
T Hinoi et al.
The American journal of pathology, 159(6), 2239-2248 (2001-12-26)
Most large bowel cancers are moderately to well-differentiated adenocarcinomas comprised chiefly or entirely of glands lined by tall columnar cells. We have identified a subset of poorly differentiated colon carcinomas with a distinctive histopathological appearance that we term large cell
Adrian Wiestner et al.
Blood, 101(12), 4944-4951 (2003-02-22)
The presence or absence of somatic mutations in the expressed immunoglobulin heavy chain variable regions (IgVH) of chronic lymphocytic leukemia (CLL) cells provides prognostic information. Patients whose leukemic cells express unmutated IgVH regions (Ig-unmutated CLL) often have progressive disease, whereas
Anna Papadopoulou et al.
European journal of pediatrics, 171(1), 51-58 (2011-05-19)
Noonan syndrome (NS) is a common multiple congenital anomaly entity, the diagnosis of which, on clinical grounds, is based on a comprehensive scoring system in order to select patients for molecular confirmation. Our aim was to evaluate the phenotypic characteristics
Y Hamano et al.
Clinical and experimental immunology, 177(1), 353-365 (2014-03-25)
The spontaneous crescentic glomerulonephritis-forming/Kinjoh (SCG/Kj) mouse, a model of human crescentic glomerulonephritis (CrGN) and systemic vasculitis, is characterized by the production of myeloperoxidase-specific anti-neutrophil cytoplasmic autoantibody (MPO-ANCA) and marked leucocytosis. This study was performed to identify the specific populations of
Bojana Crček et al.
Molecules (Basel, Switzerland), 17(5), 5363-5384 (2012-05-10)
A library of 24 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides 10{1,2; 1-12} was prepared by a parallel solution-phase approach. The synthesis comprises a five-step transformation of itaconic acid (11) into 1-methyl and 1-phenyl substituted 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxylic acids 17{1,2} followed by parallel amidation of 17{1,2} with a
Yang Cao et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 42(1), 346-356 (2017-05-24)
The contribution of the inflammatory mediator interleukin-17 (IL-17) in nonsmall cell lung cancer (NSCLC) malignancy has been reported in the literature. MicroRNA-181a-5p (miR-181a-5p) acts as a tumor suppressor which can regulate target gene at the posttranscriptional level. Our study aimed
Tomohiro Arikawa et al.
European journal of immunology, 40(2), 548-558 (2009-11-11)
Galectin-9 (Gal-9) plays pivotal roles in the modulation of innate and adaptive immunity to suppress T-cell-mediated autoimmune models. However, it remains unclear if Gal-9 plays a suppressive role for T-cell function in non-autoimmune disease models. We assessed the effects of
Corneliu N Craciunescu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 107(1), 220-226 (2008-10-25)
Diethanolamine (DEA) is a common ingredient of personal care products. Dermal administration of DEA diminishes hepatic stores of the essential nutrient choline and alters brain development. We previously reported that 80 mg/kg/day of DEA during pregnancy in mice reduced neurogenesis
Shuo Zhang et al.
Lipids, 41(6), 623-626 (2006-09-20)
A mutant of Mortierella alpina, JT-180, which is defective in its delta12 desaturase activity but exhibits enhanced activities of delta5 and delta6 desaturases, produced a high proportion (up to 80%) of odd-chain FA when grown on 3% n-heptadecane. Following growth
J M Green et al.
Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 61(1), 15-22 (1983-01-01)
A radioisotopic assay for cytoplasmic estradiol-17 beta sulfotransferase activity in rat liver was developed. Routine enzyme assays used 120 microM [3H]estradiol-17 beta, 240 microM 3'-phosphoadenosine-5'-phosphosulfate, and enzyme samples containing up to 0.60 mg of cytosol protein. Livers from males and
Kylie A Alexander et al.
The Journal of clinical investigation, 124(10), 4266-4280 (2014-08-27)
Chronic GVHD (cGVHD) is the major cause of late, nonrelapse death following stem cell transplantation and characteristically develops in organs such as skin and lung. Here, we used multiple murine models of cGVHD to investigate the contribution of macrophage populations
Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.
S-M Lee et al.
Diabetologia, 54(5), 1136-1146 (2011-02-23)
We recently found that activation of the type III histone deacetylase sirtuin 1 suppresses T cell immune responses. Here we sought to determine the therapeutic potential of the sirtuin 1 activator resveratrol in the treatment of diabetes in the NOD
T P Knepper et al.
Biochemistry, 31(46), 11651-11659 (1992-11-24)
The primary structure of mouse interleukin-3 (IL-3) expressed by recombinant baculovirus-infected silkworm (Bombyx mori) larvae was analyzed by subjecting isolated IL-3 derived peptides to liquid secondary ion mass spectrometry. Two species of IL-3 were isolated from the silkworm hemolymph by
Catherine Uyttenhove et al.
European journal of immunology, 40(8), 2230-2235 (2010-06-12)
TGF-β and IL-4 were recently shown to selectively upregulate IL-9 production by naïve CD4(+) T cells. We report here that TGF-β interactions with IL-1α, IL-1β, IL-18, and IL-33 have equivalent IL-9-stimulating activities that function even in IL-4-deficient animals. This was
Horacio F Olivo et al.
Bioorganic & medicinal chemistry letters, 20(3), 1153-1155 (2009-12-25)
We have synthesized an analog of dehydroepiandrosterone (DHEA, 1) containing both a benzophenone (BP) and a biotin (Bt) group (DHEA-BP-Bt, 8). Compound 8 was prepared by functionalization on C-17 of 1. Biocytin was reacted with 4-benzoylbenzoic acid and the product
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