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A Georgopoulos et al.
The Journal of clinical endocrinology and metabolism, 85(9), 3155-3160 (2000-09-22)
Patients with type 2 diabetes are frequently dyslipidemic or hypertriglyceridemic. To assess whether increased intestinal triglyceride input leads to elevated fasting and postprandial triglycerides in type 2 diabetes, we used the codon 54 polymorphism of the fatty acid-binding protein 2
Daniel Buxton et al.
American journal of clinical pathology, 131(4), 574-579 (2009-03-18)
Originally described as a diagnostically useful marker for Ewing sarcoma, CD99 immunoreactivity has also been documented in a variety of other tumors, including hematopoietic neoplasms. By using conventional paraffin immunoperoxidase staining and tissue microarrays, we retrospectively investigated CD99 expression in
N Carlo-Stella et al.
Clinical and experimental rheumatology, 24(2), 179-182 (2006-06-10)
In the past two years we have developed a biological bank of genomic DNA, cDNA, serum and red blood cells of Italian patients with certified CFS from the two Italian referral centers for the syndrome. Recent studies have shown an
Sibel Yilmaz-Oner et al.
The Journal of rheumatology, 42(11), 2066-2070 (2015-10-17)
Remission is the primary aim in the treatment of patients with rheumatoid arthritis (RA). In this study, we aimed to evaluate biomarker profiles of patients in remission by different criteria and compare these profiles with controls. Serum levels of calprotectin
Jung Min Choi et al.
PloS one, 15(12), e0244062-e0244062 (2020-12-17)
In percutaneous coronary intervention, drug-eluting stent (DES) showed better clinical outcome compared to bare-metal stent (BMS) but mostly with different DAPT durations. The clinical superiority of DES over BMS may depend on the medication adherence to dual antiplatelet therapy (DAPT).
Karl Insogna et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 17 Suppl 2, N108-N116 (2002-11-05)
We have observed a strong correlation between circulating levels of both interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) and rates of bone turnover in patients with primary hyperparathyroidism. Furthermore, we have found that serum levels of IL-6sR predict rates of
R Aller et al.
European review for medical and pharmacological sciences, 13(5), 357-364 (2009-12-08)
A transition G to A at codon 54 of fatty acid binding protein type 2 (FABP2) produces an amino acid substitution (Ala 54 to Thr 54). This amino acid substitution was associated with modifications of insulin resistance, adipokines and insulin
Anthony J G D Holtmaat et al.
Neuron, 45(2), 279-291 (2005-01-25)
Dendritic spines were imaged over days to months in the apical tufts of neocortical pyramidal neurons (layers 5 and 2/3) in vivo. A fraction of thin spines appeared and disappeared over a few days, while most thick spines persisted for
G N Stradling et al.
Human & experimental toxicology, 14(2), 165-169 (1995-02-01)
1. With DTPA as a comparison, the siderophore analogue 3,4,3-LIHOPO has been examined for its ability to remove 228Th nitrate from the rat after subcutaneous (sc) and intramuscular (im) injection to simulate wound contamination. The commencement of treatment was delayed
Soo-Jeong Lim et al.
International journal of pharmaceutics, 243(1-2), 135-146 (2002-08-15)
Solid lipid nanoparticles (SLNs) have gained attention as a colloidal drug carrier, particularly for drugs with limited solubility. The poor aqueous solubility of all-trans retinoic acid (ATRA) has been a limiting factor in its clinical use. This study was undertaken
Akira Tsuburaya et al.
The Lancet. Oncology, 15(8), 886-893 (2014-06-24)
The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant Multi-Institutional group Trial (SAMIT) to assess the superiority of sequential treatment (paclitaxel then tegafur and uracil [UFT] or paclitaxel then
Jan Hüsch et al.
Journal of natural products, 75(10), 1675-1682 (2012-09-28)
Boswellia serrata gum resin extracts are used widely for the treatment of inflammatory diseases. However, very low concentrations in the plasma and brain were observed for the boswellic acids (1-6, the active constituents of B. serrata). The present study investigated
Timothy R Fennell et al.
Xenobiotica; the fate of foreign compounds in biological systems, 48(11), 1142-1156 (2017-11-08)
1. 2-Ethylhexyl-p-methoxycinnamate (EHMC) is commonly used as an ingredient in sunscreens, resulting in potential oral and dermal exposure in humans. 2. Clearance and metabolism of EHMC in hepatocytes and disposition and metabolism of EHMC in rodents following oral (8-800 mg/kg) intravenous
Beatriz Cabanillas et al.
Molecular nutrition & food research, 56(12), 1884-1893 (2012-10-20)
The aims of this study were to evaluate IgE-mediated hypersensitivity to pine nut with details of clinical reactions and to characterize major pine nut allergens. The study included ten consecutive teenagers and adults diagnosed with IgE-mediated clinical allergy to pine
Eija A Korkeila et al.
Human pathology, 42(3), 384-392 (2010-12-31)
The purpose of this study was to assess the value of ezrin expression as a predictor of disease outcome in rectal cancer treated by preoperative radio- or chemoradiotherapy. Operative samples from 176 rectal cancer patients and 76 diagnostic preoperative biopsies
Sarangadhara Appala Raju Bagadi et al.
Breast cancer research and treatment, 104(3), 277-286 (2006-11-23)
Disabled-2 (Dab2), a putative tumor suppressor protein, is lost in 80-90% ovarian tumors and ovarian/breast cancer cell lines. The clinical significance of Dab2 protein in breast cancer remains yet unknown. Immunohistochemical analysis of Dab2 protein showed no detectable expression in
Harun Badakhshi et al.
Anticancer research, 33(9), 4111-4115 (2013-09-12)
Concurrent radiochemotherapy (cRCT) is the standard-of-care for patients with locally advanced anal cancer. There is a subgroup of patients however, vastly with small tumors, which undergo local excision before combined modality treatment. It was suggested that local excision prior to
Katarzyna Popko et al.
European journal of medical research, 15 Suppl 2, 120-122 (2010-12-22)
The development of obesity and related disorders, e.g., type II diabetes (T2D), hypertension, and metabolic disturbances is strongly related to increased levels in proinflammatory cytokines (IL-1, IL-6, and TNF-α). Both IL-6 and TNF-α are secreted by adipocytes and their concentration
Jonathan F Kalisvaart et al.
Journal of pediatric urology, 8(4), 359-365 (2011-08-09)
Follow-up of patients undergoing dextranomer/hyaluronic acid injection for vesico-ureteral reflux (VUR) is controversial. The purpose of our study was to test the hypothesis that patients undergoing the double hydrodistention-implantation technique (Double HIT) have a higher clinical and radiographic success rate.
C C Wu et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 39(6), 563-569 (2001-05-11)
The modulation of garlic oil (GO) and three allyl compounds, diallyl sulfide (DAS), diallyl disulfide (DADS) and diallyl trisulfide (DATS), on the antioxidation system in rat livers and red blood cells was examined. Rats were orally administered GO (200 mg/kg
Chiara Della Bella et al.
PloS one, 13(6), e0197825-e0197825 (2018-06-02)
Tuberculosis (TB) still is a major worldwide health problem, with 10.4 million new cases in 2016. Only 5-15% of people infected with M. tuberculosis develop TB disease while others remain latently infected (LTBI) during their lifetime. Thus, the absence of
Jian-Yong Zhu et al.
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 30(12), 912-917 (2008-03-14)
To investigate the association between polymorphisms of the serotonin 2A, 2C receptor genes and obstructive sleep apnea-hypopnea syndrome (OSAHS), and therefore to explore the genotypes related to OSAHS. The T102C and A1438G polymorphisms of the serotonin 2A receptor genes and
Keizo Yoshida et al.
Journal of psychopharmacology (Oxford, England), 21(6), 650-656 (2006-11-10)
Prediction of the response to different classes of antidepressants has been an important matter of concern in the field of psychopharmacology. The purpose of the present study was to investigate whether the G196A polymorphism of the brain-derived neurotrophic factor (BDNF)
K S Barron et al.
Arthritis and rheumatism, 38(5), 684-689 (1995-05-01)
Although HLA-B27 is strongly associated with susceptibility to Reiter's syndrome (RS), recent data suggest that an additional modifying or susceptibility gene(s) acts in concert with HLA-B27 to contribute to disease pathogenesis. The recently described TAP genes (transporters associated with antigen
Diego Iglesias et al.
Clinical biochemistry, 48(16-17), 1059-1063 (2015-06-16)
The aim of this study was to evaluate the effects of acute hypobaric hypoxia (HH) on vascular reactivity and biochemical markers associated with endothelial function (EF). Ten healthy subjects were exposed to a simulated altitude of 4,000 meters above sea
Rolando M D'Angelillo et al.
International journal of radiation oncology, biology, physics, 90(2), 296-302 (2014-08-03)
To retrospectively review data of a cohort of patients with biochemical progression after radical prostatectomy, treated according to a uniform institutional treatment policy, to evaluate toxicity and feasibility of high-dose salvage radiation therapy (80 Gy). Data on 60 patients with
Kendall F Moseley et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 28(3), 497-504 (2012-09-20)
The dietary acid load created by the typical Western diet may adversely impact the skeleton by disrupting calcium metabolism. Whether neutralizing dietary acid with alkaline potassium salts results in sustained improvements in calcium balance remains controversial. In this randomized, double-blind
Rukmali Athurupana et al.
Theriogenology, 84(6), 940-947 (2015-07-02)
Thawing process is important in semen cryopreservation as it brings back the sperm cell to physiologic temperature reactivating the metabolism. Aims of the present study were to evaluate survival rate and in vitro penetrability of boar frozen spermatozoa after rapid
Anne Pham-Ledard et al.
The Journal of investigative dermatology, 130(3), 816-825 (2009-10-09)
The identification of IFN regulatory factor 4 gene (IRF4) translocation in 8 out of 14 cases of cutaneous anaplastic large cell lymphomas (C-ALCLs) (Leukemia, 2009; 23(3):574-80) prompted us to study IRF4 locus status in different cutaneous T-cell lymphoma (CTCL) subtypes.
Rachel E Farquhar et al.
Frontiers in physiology, 13, 905834-905834 (2022-07-15)
Targeting proteins to a specific membrane is crucial for proper epithelial cell function. KCa3.1, a calcium-activated, intermediate-conductance potassium channel, is targeted to the basolateral membrane (BLM) in epithelial cells. Surprisingly, the mechanism of KCa3.1 membrane targeting is poorly understood. We
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