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显示 31-60 共 135 条结果 关于 "80100" 范围 论文
Zhixing He et al.
Bioresource technology, 128, 526-532 (2012-12-04)
HD-1, a stable microbial consortium capable of mineralizing di-n-butyl phthalate (DBP), was developed from activated sludge. The dominant microorganisms in the consortium, Gordonia sp., Burkholderia sp. and Achromobacter sp., were identified by denaturing gradient gel electrophoresis (DGGE). The consortium could
Samuel Beck et al.
Nature communications, 5, 5490-5490 (2014-11-19)
Both transcriptional and epigenetic regulations are fundamental for the control of eukaryotic gene expression. Here we perform a compendium analysis of >200 large sequencing data sets to elucidate the regulatory logic of global gene expression programs in mouse embryonic stem
Xiu-Juan Li et al.
Environmental toxicology and pharmacology, 36(2), 392-402 (2013-06-06)
Dibutyl-phthalate (DBP) is a ubiquitous environmental contaminant. However, its neurotoxic effects on neonatal, immature or mature brains remain unclear. Here, we aimed to investigate the neurotoxicity of perinatal exposure of DBP on rodent offspring animals. Pregnant rats received intragastric DBP
Vivian Wing-Yi Li et al.
The American journal of cardiology, 115(3), 348-353 (2014-12-09)
We assessed the left ventricular (LV) contractile reserve in young adults with repaired coarctation of the aorta and interrupted aortic arch by determination of LV force-frequency relation (FFR). Eighteen (7 men) patients aged 24.2 ± 5.4 years and 20 (9
Harpreet Bhatia et al.
Environmental toxicology and chemistry, 32(10), 2335-2344 (2013-06-14)
Di-n-butyl phthalate (DnBP) is an industrial pollutant with antiandrogenic effects reported in male mammals and fish. Little research has been done on the endocrine effects of DnBP in female fish. The present study investigated the changes in ovarian histology and
Gordon C C Yang et al.
Journal of hazardous materials, 277, 53-61 (2014-04-08)
This study monitored the occurrence and removal efficiencies of 8 phthalate esters (PAEs) and 13 pharmaceuticals present in the drinking water of Kaohsiung City, Taiwan. The simultaneous electrocoagulation and electrofiltration (EC/EF) process was used to remove the contaminants. To this
Matthew Lorber et al.
Environment international, 59, 469-477 (2013-08-21)
In a published controlled dosing experiment, a single individual consumed 5mg each of labeled di-n-butyl phthalate (DnBP) and diisobutyl phthalate (DiBP) on separate occasions and tracked metabolites in his blood and urine over 48h. Data from this study were used
Meili Zheng et al.
Medicine, 93(29), e262-e262 (2014-12-30)
Blood pressure (BP) changes with age. We conducted a cross-sectional study in rural Chinese adults to investigate: (1) what is the relationship between age, arterial stiffness, and BP in Chinese men and women; and (2) to what degree can the
T Fierens et al.
Environment international, 73, 117-127 (2014-08-13)
In this study, a semi-probabilistic modelling approach was applied for the estimation of the long-term human dietary exposure to phthalates--one of world's most used families of plasticisers. Four phthalate compounds were considered: diethyl phthalate (DEP), di-n-butyl phthalate (DnBP), benzylbutyl phthalate
Thomas B Thornley et al.
The Journal of clinical investigation, 124(8), 3443-3454 (2014-07-02)
Macrophages characterized as M2 and M2-like regulate immune responses associated with immune suppression and healing; however, the relationship of this macrophage subset to CD169+ tissue-resident macrophages and their contribution to shaping alloimmune responses is unknown. Here we identified a population
Kyoko Kumagai et al.
Journal of hypertension, 33(2), 323-329 (2014-11-08)
Although central blood pressure (BP) is considered to be more closely associated with large arterial remodeling and cardiovascular outcomes than brachial BP, few studies have investigated these associations with changes in small arteries. As morphological changes in retinal vessels might
Nobuya Inagaki et al.
Journal of diabetes investigation, 6(2), 210-218 (2015-03-25)
Canagliflozin is a sodium-glucose cotransporter 2 inhibitor under development for the treatment of type 2 diabetes. Our aim was to examine its efficacy and safety as monotherapy or in combination with commonly used oral antihyperglycemic drugs in Japanese patients with
Matthew Carran et al.
The New Zealand medical journal, 125(1358), 52-63 (2012-08-07)
It is well known that the endocrine-disrupting chemical (EDC) dibutylphthalate (DBP) inhibits testosterone synthesis and can lead to feminisation in male laboratory animals. Moreover, it has long been speculated that human exposure would result in the similar effects, but this
Rebecca A Clewell et al.
Reproductive toxicology (Elmsford, N.Y.), 35, 70-80 (2012-09-05)
Male rat sexual development was evaluated after dietary administration of 0, 760, 3800, 11,400 ppm diisononyl phthalate (DiNP) and 7600 ppm dibutyl phthalate (DBP) from gestation day (GD) 12 to postnatal day (PND) 14. Maternal weight was reduced on GD
Zelieann R Craig et al.
Biology of reproduction, 88(1), 23-23 (2012-12-18)
Di-n-butyl phthalate (DBP) is present in many consumer products, such as infant, beauty, and medical products. Several studies have shown that DBP causes reproductive toxicity in rodents, but no studies have evaluated its effects on ovarian follicles. Therefore, we used
Gabriella M Anic et al.
Lung cancer (Amsterdam, Netherlands), 86(3), 297-303 (2014-12-03)
Vitamin D may prolong cancer survival by inhibiting tumor progression and metastasis, however, there are limited epidemiologic studies regarding the association between circulating 25-hydroxyvitamin D (25(OH)D) and lung cancer survival. The aim of this study was to examine the relationship
Jose-Alberto Palma et al.
Movement disorders : official journal of the Movement Disorder Society, 30(5), 639-645 (2015-02-14)
Orthostatic hypotension (OH) is frequent in patients with Parkinson's disease (PD) and can occur with or without symptoms. Pharmacological treatments are effective, but often exacerbate supine hypertension. Guidelines exist for the diagnosis, but not for the treatment of OH. We
Shukang Wang et al.
BMC public health, 15, 7-7 (2015-01-18)
Obesity is a major independent risk factor for chronic diseases such as hypertension and coronary diseases, it might not be only related to the amount of body fat but its distribution. The single body mass index (BMI), waist circumference (WC)
Shabnam Shokouhi et al.
Canadian journal of diabetes, 39(1), 65-72 (2014-10-06)
The peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene could play a role in the onset of type 2 diabetes mellitus. The aim of this study was to explore the possible associations among polymorphisms Gly482Ser, Thr394Thr and Thr528Thr of the PGC-1alpha
Hermann Fromme et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 272-280 (2012-12-19)
Phthalates as well as di-(2-ethylhexyl) adipate (DEHA) are used as plasticizers in diverse applications and are of toxicological concern. The study was conducted with a study population of 25 German subjects aged between 15 and 21 months. Overall, 16 phthalates
Sheng-Feng Hung et al.
PloS one, 9(6), e100321-e100321 (2014-06-27)
Effervescent multiple-unit floating drug delivery systems (muFDDSs) consisting of drug (lorsartan)- and effervescent (sodium bicarbonate)-containing pellets were characterized in this study. The mechanical properties (stress and strain at rupture, Young's modulus, and toughness) of these plasticized polymeric films of acrylic
Qiliu Peng et al.
PloS one, 9(12), e116026-e116026 (2014-12-30)
Polymorphisms of genes encoding components of the vitamin D pathway including vitamin D receptor (VDR) and vitamin D binding protein (DBP) have been widely investigated because of the complex role played by vitamin D in cancer tumorogenesis. In this study
An approach for integrating toxicogenomic data in risk assessment: the dibutyl phthalate case study.
Susan Y Euling et al.
Toxicology and applied pharmacology, 271(3), 324-335 (2013-03-30)
An approach for evaluating and integrating genomic data in chemical risk assessment was developed based on the lessons learned from performing a case study for the chemical dibutyl phthalate. A case study prototype approach was first developed in accordance with
Guoxing Wang et al.
PloS one, 10(3), e0121968-e0121968 (2015-03-24)
Previous studies have demonstrated that the cell surface receptor Slamf1 (CD150) is requisite for optimal NADPH-oxidase (Nox2) dependent reactive oxygen species (ROS) production by phagocytes in response to Gram- bacteria. By contrast, Slamf8 (CD353) is a negative regulator of ROS
Simon M Plummer et al.
Toxicological sciences : an official journal of the Society of Toxicology, 132(2), 443-457 (2013-01-30)
Previous analysis of in utero dibutylphthalate (DBP)-exposed fetal rat testes indicated that DBP's antiandrogenic effects were mediated, in part, by indirect inhibition of steroidogenic factor 1 (SF1), suggesting that peroxisome proliferator-activated receptor alpha (PPARα) might be involved through coactivator (CREB-binding
Biqi Wang et al.
Twin research and human genetics : the official journal of the International Society for Twin Studies, 18(2), 158-170 (2015-03-07)
The genetic contribution of blood pressure and heart rate (HR) varied widely between studies. Demographic factors such as ethnicity, age and/or sex might explain some of the heterogeneity. We performed a systematic review focusing on four phenotypes: systolic blood pressure
Richard Ivell et al.
Asian journal of andrology, 15(2), 261-268 (2013-01-15)
Maternal exposure to estrogenic xenobiotics or phthalates has been implicated in the distortion of early male reproductive development, referred to in humans as the testicular dysgenesis syndrome. It is not known, however, whether such early gestational and/or lactational exposure can
I Shiue
European journal of neurology, 20(4), 728-731 (2012-09-13)
Associations between plastic-associated chemicals, such as bisphenol A, and cardiovascular disease have begun to emerge in the current century. However, the relationship between urine phthalates and risk of stroke is unclear. It was aimed to study the relationship between urine
Li Zhang et al.
Journal of chromatography. A, 1386, 22-30 (2015-02-24)
A new analytical method was established and validated for the analysis of 19 substances of very high concern (SVHCs) in textiles, including phthalic acid esters (PAEs), organotins (OTs), perfluorochemicals (PFCs) and flame retardants (FRs). After ultrasonic extraction in methanol, the
Harpreet Bhatia et al.
Aquatic toxicology (Amsterdam, Netherlands), 149, 103-115 (2014-03-01)
Phthalic acid esters (PAEs) are a class of synthetic industrial chemicals commonly found in the aquatic environment worldwide. PAEs have been recognised as anti-androgens in male mammals but little is known about their endocrine disrupting effects in fish. This study
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