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J Cebon et al.
British journal of cancer, 95(7), 853-861 (2006-09-06)
Octreotide may extend survival in hepatocellular carcinoma (HCC). Forty-one per cent of HCCs have high-affinity somatostatin receptors. We aimed to determine the feasibility, safety, and activity of long-acting octreotide in advanced HCC; to identify the best method for assessing somatostatin
Shahram Ala et al.
Acta gastro-enterologica Belgica, 75(4), 438-442 (2013-02-14)
Chemical sphincterotomy is a new way for the treatment of chronic anal fissure which avoids the risk of faecal incontinence associated with traditional surgical methods. The aim of this study was to compare topical Diltiazem with topical Glyceril trinitrate in
Sumin Lee et al.
Journal of food science, 81(1), T262-T267 (2015-12-15)
In this study, the effect of food additives such as iron sulfate, magnesium sulfate, zinc sulfate, citric acid, gallic acid, and ascorbic acid on the reduction of 4(5)-methylimidazole (4(5)-MI) was investigated using a soy sauce model system. The concentration of
Shyam Sundar et al.
Tropical medicine & international health : TM & IH, 18(1), 96-100 (2012-11-10)
Standard treatment of Indian post-kala-azar dermal leishmaniasis (PKDL) is unsatisfactory because to achieve therapeutic effectiveness, heroic courses of parenteral and toxic agents have to be administered. Our objective was to evaluate oral miltefosine for its potential to provide effective as
Terhi Alaviuhkola et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 11(7), 2071-2080 (2005-01-28)
Five aromatic borate anions, namely tetrakis(4-phenoxyphenyl)borate (1), tetrakis(biphenyl)borate (2), tetrakis(2-naphthyl)borate (3), tetrakis(4-phenylphenol)borate (4), and tetrakis(4-phenoxy)borate (5), have been prepared and tested as ion-recognition sites in chemical sensors for certain aromatic cations and metal ions. To gain further insight into the
Keren Tuvia Baron et al.
Emergency radiology, 19(6), 519-525 (2012-08-14)
The objectives of this study were to document the utilization of MRI compared with CT in pregnant patients presenting with acute nontraumatic abdominal pain at our institution and to compare the diagnostic performance of the two modalities. A retrospective review
W M Heijbroek et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(3), 235-247 (1984-03-01)
The metabolism of [ring-14C]asulam, a systemic herbicide highly effective against bracken, has been studied in rats. Most of the radioactivity (76-100% dose) administered orally or intravenously is excreted in the urine in 24 h as unchanged asulam (61-74% dose), N4-acetylasulam
A A Jungbluth et al.
The American journal of surgical pathology, 22(5), 595-602 (1998-05-20)
Melan-A is a previously defined, melanocyte differentiation antigen, and an anti-Melan-A murine monoclonal antibody, A103, was recently developed by our group. In this study, we evaluated A103 immunoreactivity on formalin-fixed, paraffin-embedded tissues, exploring the potential of A103 in the diagnosis
J E Stegner et al.
Journal of animal science, 82(4), 1016-1021 (2004-04-15)
Two progestin-based protocols for estrus synchronization in postpartum beef cows were compared following treatment administration on the basis of estrous response, interval to and synchrony of estrus, and pregnancy. Cows were assigned to one of the two treatment protocols by
Salih Pay et al.
Joint, bone, spine : revue du rhumatisme, 73(6), 691-696 (2006-09-22)
To analyze the CXCR-1 and CXCR-2 chemokine receptor expression on peripheral blood neutrophils (PBN) and synovial fluid neutrophils (SFN) of patients with rheumatoid arthritis (RA) and Behçet's disease (BD) (characterized by erosive and non-erosive arthritis, respectively), and to compare them
Francis Y Yao et al.
Hepatology (Baltimore, Md.), 61(6), 1968-1977 (2015-02-19)
We report on the long-term intention-to-treat (ITT) outcome of 118 patients with hepatocellular carcinoma (HCC) undergoing downstaging to within Milan/United Network for Organ Sharing T2 criteria before liver transplantation (LT) since 2002 and compare the results with 488 patients listed
Morris D Groves et al.
Journal of neuro-oncology, 94(2), 229-234 (2009-03-10)
Breast cancer, lung cancer and melanoma metastasize to the meninges in 5-15% of patients. The identification of specific biomarkers of disease may allow for earlier diagnosis and treatment. Preclinical evidence suggests the possible relevance of SDF-1 and VEGF in the
Mary Jo Fackler et al.
International journal of cancer, 107(6), 970-975 (2003-11-06)
Little is known about epigenetic silencing of genes by promoter hypermethylation in lobular breast cancers. The promoter methylation status of 5 cancer-related genes (RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist) was evaluated in 2 types of lobular cancers, in situ
D Tesfaye et al.
Reproduction (Cambridge, England), 139(5), 857-870 (2010-02-24)
This study was conducted to investigate the effect of suppressing transcription factor gene MSX1 on the development of in vitro produced bovine oocytes and embryos, and identify its potential target genes regulated by this gene. Injection of long double-stranded RNA
Lionel D Lewis et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 13(11), 3302-3311 (2007-06-05)
Increased clearance of drugs, such as oral cyclosporine, that are CYP3A and/or ABCB1 (P-gp/MDR1) substrates was reported in African-American compared with Caucasian patients. We hypothesized that the pharmacokinetics and pharmacodynamics of docetaxel, an i.v. administered cytotoxic and substrate for CYP3A4
Fang-Qiu Li et al.
BMC cancer, 10, 429-429 (2010-08-18)
Sperm protein 17 (Sp17) is a highly conserved mammalian protein in the testis and spermatozoa and has been characterized as a tumor-associated antigen in a variety of human malignancies. Many studies have examined the role of Sp17 in tumorigenesis and
Jacqueline A French et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 9(1), 176-184 (2011-12-06)
The efficacy and safety of lamotrigine extended-release tablets (LTG XR) as monotherapy for partial seizures were evaluated using the conversion-to-monotherapy design, and historical data as the control. This methodology was recently approved by the United States Food and Drug Administration
Andre Dos Santos Rocha et al.
Frontiers in physiology, 11, 625777-625777 (2021-02-02)
The advantages of physiologically variable ventilation (PVV) based on a spontaneous breathing pattern have been demonstrated in several respiratory conditions. However, its potential benefits in chronic obstructive pulmonary disease (COPD) have not yet been characterized. We used an experimental model
Delphine Détaint et al.
European heart journal, 31(18), 2223-2229 (2010-08-17)
In patients with Marfan syndrome and other type-1 fibrillinopathies, genetic testing is becoming more easily available, leading to the identification of mutations early in the course of the disease. This study evaluates the cardiovascular (CV) risk associated with the discovery
Julia V Johnson et al.
Obstetrics and gynecology, 111(2 Pt 1), 278-284 (2008-02-02)
To compare the effects of oral and transdermal contraceptives containing similar hormone formulations on vascular risk markers. We conducted a randomized, investigator-blinded, crossover, clinical trial with 24 healthy women, aged 18-35 years, who received 2 months of transdermal or oral
Albert J W Zendman et al.
International journal of cancer, 97(2), 195-204 (2002-01-05)
Suppression subtractive hybridization, comparing mRNA expression profiles of common nevocellular nevi and melanoma metastases, was used to identify potential markers of melanoma progression. From the metastases we isolated XAGE-1b, a 470 bp transcript of the XAGE-1 gene. In general, expression
Sofia Ribeiro et al.
Acta biomaterialia, 121, 303-315 (2020-11-24)
Although it has been repeatedly indicated the importance to develop implantable devices and cell culture substrates with tissue-specific rigidity, current commercially available products, in particular cell culture substrates, have rigidity values well above most tissues in the body. Herein, six
Yi Li et al.
Zhonghua nei ke za zhi, 47(3), 213-216 (2008-09-13)
To investigate the association between the exon 2, 3, 4 of MHC class I chain-related gene-B (MICB) and ulcerative colitis (UC) in Chinese Han. Using polymerase chain reaction single-stranded conformation polymorphism, allele frequency of MICB exon 2, 3 and 4
Els van Pamel et al.
Analytical and bioanalytical chemistry, 407(15), 4485-4494 (2015-03-31)
This study concerns a validated liquid chromatographic/tandem mass spectrometric (LC-MS/MS) multiresidue method for the simultaneous detection, identification, and quantitation of 15 nonsteroidal anti-inflammatory drugs (NSAIDs) in bovine meat and milk. The NSAIDs considered are carprofen, diclofenac, flufenamic acid, flunixin (5-hydroxyflunixin
Lovemore Kunorozva et al.
Chronobiology international, 29(8), 1004-1010 (2012-09-14)
A link between diurnal preference and a variable number tandem-repeat (VNTR) polymorphism in the PERIOD3 gene (PER3) has been demonstrated: the longer PER3(5) and shorter PER3(4) alleles with preferences for mornings and evenings, respectively. As many competitive events in South
Magdalena Alonso-Galicia et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 283(1), R60-R68 (2002-06-19)
The present study examined the effects of ANG II on the renal synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) and its contribution to the renal vasoconstrictor and the acute and chronic pressor effects of ANG II in rats. ANG II (10(-11) to
A J A Meershoek et al.
The British journal of surgery, 106(6), 665-671 (2019-04-12)
Guidelines recommend treating patients with an internal carotid artery near occlusion (ICANO) with best medical therapy (BMT) based on weak evidence. Consequently, patients with ICANO were excluded from randomized trials. The aim of this individual-patient data (IPD) meta-analysis was to
Lena Ohlsson et al.
Regulatory peptides, 189, 40-45 (2014-03-04)
Using a newly developed in vivo model measuring glucagon-like peptide-1 (GLP-1) in gut lymphatics in mice, we quantified GLP-1 secretion in vivo after glucose versus fat ingestion with and without concomitant DPP-4 inhibition. The mesenteric lymphatic duct was cannulated in
Matthias Eiber et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 56(5), 668-674 (2015-03-21)
The expression of prostate-specific membrane antigen (PSMA) is increased in prostate cancer. Recently, (68)Ga-PSMA (Glu-NH-CO-NH-Lys-(Ahx)-[(68)Ga(HBED-CC)]) was developed as a PSMA ligand. The aim of this study was to investigate the detection rate of (68)Ga-PSMA PET/CT in patients with biochemical recurrence
Reginald Bell et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 18(8), 1736-1743 (2019-09-14)
Regurgitative gastroesophageal reflux disease (GERD) refractive to medical treatment is common and caused by mechanical failure of the anti-reflux barrier. We compared the effects of magnetic sphincter augmentation (MSA) with those of proton-pump inhibitors (PPIs) in a randomized trial. Patients
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