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显示 31-48 共 48 条结果 关于 "810150C" 范围 论文
Shuo Lu et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(19), 10313-10321 (2020-04-29)
The H+/Ca2+ (calcium ion) antiporter (CAX) plays an important role in maintaining cellular Ca2+ homeostasis in bacteria, yeast, and plants by promoting Ca2+ efflux across the cell membranes. However, how CAX facilitates Ca2+ balance in response to dynamic cytosolic Ca2+
Stabilization of liposomes against stress using polyelectrolytes: Interaction mechanisms, influence of pH, molecular weight, and polyelectrolyte structure
Rinaudo M, et al.
International Journal of Polymer Analysis and Characterization, 14(8), 667-677 (2009)
Tun Naw Sut et al.
Langmuir : the ACS journal of surfaces and colloids, 35(47), 15063-15070 (2019-11-02)
Supported lipid bilayers (SLBs) are simplified model membrane systems that mimic the fundamental properties of biological cell membranes and allow the surface-sensitive tools to be used in numerous sensing applications. SLBs can be prepared by various methods including vesicle fusion
Sanjay Arora et al.
ACS chemical neuroscience, 11(11), 1620-1633 (2020-05-01)
Alzheimer's disease (AD), the most common cause of dementia, inflicts enormous suffering to patients and their family members. It is the third deadliest disease, affecting 46.8 million people worldwide. Brain-derived neurotrophic factor (BDNF) is involved in the development, maintenance, and
Heun Jin Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(49), 19253-19257 (2008-12-03)
Recent advances have enabled 3-dimensional reconstructions of biological structures in vivo, ranging in size and complexity from single proteins to multicellular structures. In particular, tomography and confocal microscopy have been exploited to capture detailed 3-dimensional conformations of membranes in cellular
Yu-Qing Wang et al.
International journal of pharmaceutics, 582, 119331-119331 (2020-04-15)
The major drawbacks of the cytotoxin like DM1 are the off-target effects. Here, the targeting nanovesicles were developed by synthesizing tocopherol-SS-DM1 and conjugating a pH low insertion peptide (pHLIP) to PEGylated phospholipids, in which tocopherol-SS-DM1 improves the drug loading and
Thuc T Le et al.
BMC cancer, 9, 42-42 (2009-02-03)
Lipid-rich tumours have been associated with increased cancer metastasis and aggressive clinical behaviours. Nonetheless, pathologists cannot classify lipid-rich tumours as a clinically distinctive form of carcinoma due to a lack of mechanistic understanding on the roles of lipids in cancer
Jorge Larios et al.
The Journal of cell biology, 219(3) (2020-02-13)
The intraluminal vesicles (ILVs) of endosomes mediate the delivery of activated signaling receptors and other proteins to lysosomes for degradation, but they also modulate intercellular communication when secreted as exosomes. The formation of ILVs requires four complexes, ESCRT-0, -I, -II
Tun Naw Sut et al.
Langmuir : the ACS journal of surfaces and colloids, 36(18), 5021-5029 (2020-04-21)
Supported lipid bilayers (SLBs) are versatile cell membrane-mimicking biointerfaces for various applications such as biosensors and drug delivery systems, and there is broad interest in developing simple, cost-effective methods to achieve SLB fabrication. One promising approach involves the deposition of
Catharina Husteden et al.
ACS applied materials & interfaces, 12(8), 8963-8977 (2020-02-01)
Biomaterials, which release active compounds after implantation, are an essential tool for targeted regenerative medicine. In this study, thin multilayer films loaded with lipid/DNA complexes (lipoplexes) were designed as surface coatings for in situ transfection applicable in tissue engineering and
Ylenia Miele et al.
Biochimica et biophysica acta. General subjects, 129611-129611 (2020-04-10)
In recent years, there has been a growing interest in the formation of copolymer-lipid hybrid self-assemblies, which allow combining and improving the main features of pure lipid-based and copolymer-based systems known for their potential applications in the biomedical field. As
Wei Wei et al.
Journal of agricultural and food chemistry, 67(50), 13922-13928 (2019-11-21)
We compared phospholipids (PLs), PL fatty acid (FA) composition, and milk fat globule size and structure in human milk (n = 120) from mothers of full-term and preterm infants during lactation (colostrum, transition, 1 mo, 2 mo, and 3 mo)
Dinesh Kumar et al.
Soft matter, 16(2), 337-347 (2019-12-06)
Lipid vesicles play a key role in fundamental biological processes. Despite recent progress, we lack a complete understanding of the non-equilibrium dynamics of vesicles due to challenges associated with long-time observation of shape fluctuations in strong flows. In this work
Oskar Staufer et al.
Small (Weinheim an der Bergstrasse, Germany), e1906424-e1906424 (2020-02-23)
Bottom-up synthetic biology has directed most efforts toward the construction of artificial compartmentalized systems that recreate living cell functions in their mechanical, morphological, or metabolic characteristics. However, bottom-up synthetic biology also offers great potential to study subcellular structures like organelles.
Daichi Yamaura et al.
Langmuir : the ACS journal of surfaces and colloids, 34(19), 5615-5622 (2018-04-18)
Artificial bilayer lipid membranes (BLMs) provide well-defined systems for investigating the fundamental properties of membrane proteins, including ion channels, and for screening the effect of drugs that act on them. However, the application of this technique is limited due to
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1831(3), 543-554 (2013)
Shuangshuang Zeng et al.
Langmuir : the ACS journal of surfaces and colloids, 36(6), 1446-1453 (2020-01-24)
Solid-state nanopores provide a highly versatile platform for rapid electrical detection and analysis of single molecules. Lipid bilayer coating of the nanopores can reduce nonspecific analyte adsorption to the nanopore sidewalls and increase the sensing selectivity by providing possibilities for
Oliver Goldmann et al.
Journal of controlled release : official journal of the Controlled Release Society, 316, 292-301 (2019-11-13)
Staphylococcus aureus is a major cause of severe invasive infections. The increasing incidence of infections caused by antibiotic-resistant strains such as methicillin-resistant S. aureus (MRSA), calls for exploration of new approaches to treat these infections. Mupirocin is an antibiotic with
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