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Molecular cloning, characterization, and promoter analysis of the human 25-hydroxyvitamin D3-1alpha-hydroxylase gene.

X F Kong et al.

Proceedings of the National Academy of Sciences of the United States of America, 96(12), 6988-6993 (1999-06-09)

The human 25-hydroxyvitamin D3-1alpha-hydroxylase (1alpha-OHase) gene has been cloned. It contained nine exons and eight introns spanning approximately 6.5 kb and a 1.4-kb 5'-flanking region. The 5'-flanking region contains consensus or highly conserved sequences for TATA, Pu, and CCAAT boxes

Association of the interleukin 1 receptor antagonist gene with ulcerative colitis in Northern European Caucasians.

M J Carter et al.

Gut, 48(4), 461-467 (2001-03-15)

An association between the allele 2 of the interleukin 1 receptor antagonist gene variable number tandem repeats polymorphism in intron 2 and ulcerative colitis was first reported in 1994. Subsequent studies in Caucasian Northern European patients have not confirmed this

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