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Edita Bagdonaite et al.
Natural product research, 27(2), 181-184 (2012-02-14)
In Lithuania, two species of the genus Fragaria L. (Rosaceae), F. vesca L. and F. viridis Weston, occur naturally in the wild and two others, F. moschata Weston and F. × ananassa Duchesne ex Rozier are found escaped from cultivation.
Joshua M Hicks et al.
Journal of AOAC International, 95(5), 1406-1411 (2012-11-28)
A single-laboratory-validated NMR spectroscopy method was established for determining the quantity of chlorogenic acid and hyperoside from crude extract material of blueberry leaves of the species Vaccinium angustifolium var. laevifolium House. The calibration curve of chlorogenic acid showed a highly
Kewu Zeng et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(17), 2409-2412 (2011-11-30)
To investigate the neuroprotective effects and mechanism of hyperin on CoCl2-induced hypoxic/ischemic PC12 cells. CoCl2 was used to treat rat pheochromocytoma cell line (PC12) to investigate the protective effects of different concentrations of hyperin. Hyperin could significantly inhibit CoCl2-induced cytotoxicity
Christian Zorzetto et al.
Fitoterapia, 100, 95-109 (2014-12-03)
In the present work we carried out a phytochemical and biological investigation on three Hypericum species, i.e. Hypericum reflexum, Hypericum canariense and Hypericum grandifolium, from the Canary Islands where they are traditionally used as diuretic, wound healing, vermifuge, sedative and
Andrea Civra et al.
BMC complementary and alternative medicine, 17(1), 74-74 (2017-01-26)
Human rotavirus (HRoV) is the leading cause of severe gastroenteritis in infants and children under the age of five years. No specific antiviral drug is available for HRoV infections and the treatment of viral diarrhea is mainly based on rehydration
Zi-lin Li et al.
Journal of ethnopharmacology, 139(2), 388-394 (2011-11-29)
Hyperoside (Hyp) is a flavonoid compound isolated from Rhododendron ponticum L. leaves that elicits vascular protective effects in vitro. Treatment with Hyp has been found to attenuate endothelial cell damage induced by oxidative stress, but its mechanisms of action remain
Ming-Zhi Zhu et al.
Molecules (Basel, Switzerland), 20(6), 10553-10565 (2015-06-11)
Lotus (Nelumbo nucifera) leaves, a traditional Chinese medicinal herb, are rich in flavonoids. In an effort to thoroughly analyze their flavonoid components, macroporous resin chromatography coupled with HPLC-MS/MS was employed to simultaneously enrich and identify flavonoids from lotus leaves. Flavonoids
Ke-Wu Zeng et al.
European journal of pharmacology, 672(1-3), 45-55 (2011-10-08)
Amyloid β-protein (Aβ), which is deposited in neurons as neurofibrillary tangles, is known to exert cytotoxic effects by inducing mitochondrial dysfunction. Additionally, the PI3K/Akt-mediated interaction between Bad and Bcl(XL) plays an important role in maintaining mitochondrial integrity. However, the application
You Jung Kim
Biological & pharmaceutical bulletin, 35(11), 2023-2027 (2012-09-14)
Hyperin and quercetin are phenolic compounds present in fruits and vegetables that have been reported to possess strong anti-oxidative properties. Although increasing evidence strongly suggests that antioxidants suppress the melanin synthesis that is causally associated with oxidative stress, the protective
Guo Ai et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(16), 2452-2455 (2012-12-14)
To observe the toxicity of hyperoside in rat embryo-fetal development, in order to provide preference for safe use of drugs during gestation period. Healthy pregnant rats were randomly divided into hyperosid groups (30, 175, 1000 mg x kg(-1) x d(-1))
Jian-ming Guo et al.
Journal of ethnopharmacology, 144(3), 664-670 (2012-10-16)
Hypericum perforatum (St. John's wort) is an important anti-depressant herb used in clinic and commonly prescribed for mild depression. Hyperoside is one of the major components of H. perforatum and is also detected in many plant species such as Abelmoschus
Zi-lin Li et al.
Free radical biology & medicine, 57, 132-140 (2013-01-08)
One of the leading causes of death in the world is ischemia/reperfusion (I/R)-mediated acute myocardial infarction. There are a lot of Chinese traditional patent medicines, such as Xin'an capsules, Xin Xuening tablets, and so on, which have protective effects against
Priscila M Outuki et al.
Pharmacognosy magazine, 11(43), 619-626 (2015-08-08)
Eschweilera nana Miers is a tree widely distributed in Cerrado, Brazil. In this study, we aimed to describe its phytochemical properties and antioxidant and topical anti-inflammatory effects for the first time, as well validate an high performance liquid chromatography with
Dongmei Wang et al.
PloS one, 9(5), e96329-e96329 (2014-05-07)
The present study was performed to investigate the variation of phytochemical composition, antioxidant activity and High Performance Liquid Chromatography (HPLC) fingerprinting profiles of three Pyrola species. Thirteen samples (eight P. decorata, three P. calliantha and two P. renifolia) were collected
Xiao Lin et al.
The Analyst, 137(17), 4076-4085 (2012-07-13)
Ionic liquids-based microwave-assisted extraction (ILs-MAE) of medicinal or useful compounds from plants was investigated as an alternative to conventional organic solvent extractions. The extraction and the preconcentration of aqueous two-phase (ATP) systems have been integrated. Various operating parameters were systematically
Sae-Kwang Ku et al.
Inflammation, 37(5), 1389-1400 (2014-03-13)
Hyperoside, an active compound from the genera of Hypericum and Crataegus, was reported to have antioxidant, antihyperglycemic, anticancer, anti-inflammatory, and anticoagulant activities. Vascular inflammatory process has been suggested to play a key role in initiation and progression of atherosclerosis, a
Hui Cao et al.
Food chemistry, 270, 257-263 (2018-09-04)
Herein, the protein binding rates of structurally different flavonoids to human serum albumin (HSA) were elucidated by applying the high performance affinity chromatography (HPAC). The flavonoids with hydroxyl groups on ring A showed a higher protein binding rate compared with
Giancarlo Statti et al.
Phytotherapy research : PTR, 29(6), 857-863 (2015-03-11)
Indian Sarsaparilla (Hemidesmus indicus R. Br.) is widely used in Indian traditional medicine. In the present work, we explored the effects of decoction, traditional Ayurvedic preparation, and hydroalcoholic extract, a phytocomplex more traditionally studied and commercialized as food supplement in
Cai-fu Xue et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 46(4), 454-459 (2011-07-15)
To explore the mechanism of the absorption of flavonoids from Abelmoschus manihot flowers, in situ intestinal recirculation was performed to study the effect of the absorption at different concentrations and different intestinal regions. To evaluate the conditions of the absorption
Meizhu Zheng et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(2), 145-149 (2011-08-02)
In the present work, we studied the possible cellular mechanisms of hyperoside isolated from Apocynum venetum leaves in corticosterone-induced neurotoxicity, using PC12 cells as a suitable in vitro model of depression. Cell viability was quantitated by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide
Xiao-Ying Yin et al.
Journal of separation science, 35(3), 384-391 (2012-01-20)
A novel method, micro-solid-phase extraction based on membrane-protected molecularly imprinted polymer, was developed to extract hyperoside and isoquercitrin in rat plasma. Synthesized hyperoside MIPs were packed in a porous polyether sulfone membrane envelope to perform extraction. The parameters sorbent materials
Cassandra L Quave et al.
PloS one, 10(8), e0136486-e0136486 (2015-08-22)
The Mediterranean is home to a rich history of medical traditions that have developed under the influence of diverse cultures over millennia. Today, many such traditions are still alive in the folk medical practices of local people. Investigation of botanical
Sae-Kwang Ku et al.
Inflammation, 38(2), 784-799 (2014-08-07)
High-mobility group box 1 (HMGB1) was recently shown to be an important extracellular mediator of systemic inflammation, and endothelial cell protein C receptor (EPCR) has been shown to be involved in vascular inflammation. Hyperoside is an active compound isolated from
Neeraj Verma et al.
Indian journal of experimental biology, 51(1), 65-72 (2013-02-28)
Antihyperglycemic potential of hyperin at 25 and 50 mg/kg doses for 30 days to streptozotocin induced diabetic rats has been reported. In oral glucose tolerance test, hyperin treated rats showed a significant reduction in blood glucose level after 120 min.
Tingting Wu et al.
Journal of pharmacological sciences, 127(3), 251-259 (2015-04-04)
Variant pharmacological activities of Zanthoxylum bungeanum were determined before. The aim of this study was to assess whether Z. bungeanum could regulate lipid metabolism. The cholesterol overloading HepG2 cells induced by sterols were used as in vitro model to study lipid-lowering
Nicole Schöbel et al.
Chemical senses, 39(6), 471-487 (2014-04-11)
Astringency is an everyday sensory experience best described as a dry mouthfeel typically elicited by phenol-rich alimentary products like tea and wine. The neural correlates and cellular mechanisms of astringency perception are still not well understood. We explored taste and
Elisabeta Baiceanu et al.
Molecules (Basel, Switzerland), 20(6), 11063-11075 (2015-06-18)
Artemisia abrotanum L. ("southernwood") belongs to the Artemisia genus and it is used in traditional medicine for the treatment of a variety of illnesses. Scarce data is available on the chemical composition of this medicinal plant, most research being focused
Sae-Kwang Ku et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 53, 197-204 (2012-12-12)
The potential anticoagulant activities of two single compounds, isorhamnetin-3-O-galactoside (IMG) and hyperoside, from Oenanthe javanica, were tested. The anticoagulant activities were investigated by measuring activated partial thromboplastin time (aPTT) and prothrombin time (PT), and the ability to inhibit production of
Longfei Lin et al.
Biomedical chromatography : BMC, 29(7), 1048-1055 (2014-12-03)
Radix polygoni multiflori (RPM) has antioxidative, anti-aging, liver-protective and antihuman cytomegalovirus activity. It has been proved to be hepatotoxic. Considering multiple ingredients to control RPM quality is essential. The aim of this study was to establish a simple, rapid method
You-Xing Zhao et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(5), 704-707 (2011-10-01)
To study the chemical constituents of the herb of Antenoron filiforme. The constituents were separated by column chromatography and their structures were elucidated by spectral data analyses. Eleven compounds were isolated from the ethanol extract of A. filiforme and identified
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