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Yin-Ku Lin et al.
PloS one, 10(9), e0137890-e0137890 (2015-09-12)
Psoriasis is a chronic inflammatory skin disease and topical therapy remains a key role for treatment. The aim of this study is to evaluate the influence of psoriasis-like lesions on the cutaneous permeation of anti-psoriatic drugs. We first set up
Iris L Kim et al.
Tissue engineering. Part A, 21(21-22), 2680-2690 (2015-09-25)
Current clinically approved methods for cartilage repair are generally based on either endogenous cell recruitment (e.g., microfracture) or chondrocyte delivery (e.g., autologous chondrocyte implantation). However, both methods culminate in repair tissue with inferior mechanical properties and the addition of biomaterials
Arianna Bertolani et al.
Nature communications, 6, 7574-7574 (2015-07-01)
Amyloid supramolecular assemblies have found widespread exploitation as ordered nanomaterials in a range of applications from materials science to biotechnology. New strategies are, however, required for understanding and promoting mature fibril formation from simple monomer motifs through easy and scalable
Sarah D Hann et al.
Soft matter, 11(9), 1733-1738 (2015-01-21)
We study the assembly of inert and living colloids in a two-phase water-water system that provides an environment that can sustain bacteria, providing a new structure with rich potential to confine and structure microbial communities. The water-water system, formed via
Ming Cai et al.
PloS one, 9(11), e111938-e111938 (2014-11-12)
To investigate the effects of hypoxic conditioned media from rat cerebral cortical cells on the proliferation and differentiation of neural stem cells (NSCs) in vitro, and to study the roles of PI3-K/Akt and JNK signal transduction pathways in these processes.
Zhenhua Chen et al.
Journal of the American Chemical Society, 135(11), 4179-4182 (2013-03-09)
Green luminescent, monodisperse, smooth, porous and hollow spheres were simply prepared by Cu(2+) and temperature mediated oxidative coupling assembly of green tea polyphenols in water. These polymeric tea polyphenol spheres are GSH responsive, acid resistant but alkali-responsive, ideally used as
Andrea M Binnebose et al.
PLoS neglected tropical diseases, 9(10), e0004173-e0004173 (2015-10-27)
Filarial diseases represent a significant social and economic burden to over 120 million people worldwide and are caused by endoparasites that require the presence of symbiotic bacteria of the genus Wolbachia for fertility and viability of the host parasite. Targeting
Qi Wang et al.
Journal of hazardous materials, 246-247, 135-144 (2013-01-10)
Amorphous TiO(2) (Am-TiO(2)) was prepared at room temperature by hydrolysis of Ti(OBu)(4) in water without addition of strong acids or organic solvents. Results from XRD and TEM revealed that the as-prepared Am-TiO(2) was composed of amorphous structure. For the simultaneous
The
A study of water circulation in Monterey harbor using rhodamine B dye (1965)
Wenyan Xie et al.
PloS one, 10(8), e0136474-e0136474 (2015-08-26)
Human parainfluenza virus type 3 (HPIV3) can cause severe respiratory tract diseases in infants and young children, but no licensed vaccines or antiviral agents are currently available for treatment. Fusing the viral and target cell membranes is a prerequisite for
Shengnan Su et al.
Journal of hazardous materials, 244-245, 736-742 (2012-12-01)
The removal of Rhodamine B (RhB) by Co(x)Fe(3-x)O(4) magnetic nanoparticles activated Oxone has been performed in this study. A series of Co(x)Fe(3-x)O(4) nanoparticles was synthesized using a hydrothermal method. The synthetic Co(x)Fe(3-x)O(4) nanoparticles were characterized using X-ray diffraction (XRD) and
Kevan Bell et al.
Electrophoresis, 36(15), 1738-1743 (2015-05-13)
Characterization of EOF mobility for Tris and TBE buffer solutions is performed in nanoporous arrays using the fluorescent marker method to examine the magnitude of EOFs through nanopores with mean diameters close to electric double layer thickness (Debye length). Structures
Shukai Yuan et al.
PLoS genetics, 11(5), e1005253-e1005253 (2015-05-29)
Hair follicles (HF) undergo precisely regulated recurrent cycles of growth, cessation, and rest. The transitions from anagen (growth), to catagen (regression), to telogen (rest) involve a physiological involution of the HF. This process is likely coordinated by a variety of
Virginia Gomez et al.
Nanoscale, 7(42), 17735-17744 (2015-10-13)
Bi-phasic or multi-phasic composite nanoparticles for use in photocatalysis have been produced by a new synthetic approach. Sol-gel methods are used to deposit multiple layers of active material onto soluble substrates. In this work, a layer of rutile (TiO2) was
Masahiro Mizuno et al.
Langmuir : the ACS journal of surfaces and colloids, 31(8), 2334-2341 (2015-02-12)
A new microfluidic process was used to generate unique micrometer-sized hierarchical lipid particles having spherical lipid-core and multilamellar-shell structures. The process includes three steps: (1) formation of monodisperse droplets in a nonequilibrium state at a microchannel confluence, using a phospholipid-containing
Tatsuya Murakami et al.
ACS nano, 8(7), 7370-7376 (2014-06-20)
Surface engineering of mesoscopic metal nanoparticles to increase biocompatibility and cell interaction is important for improvement of their therapeutic properties. Here, we describe a strategy to stabilize mesoscopic metal nanoparticles and to enhance their cell interaction by stepwise addition of
Brett P Gross et al.
The AAPS journal, 16(6), 1194-1203 (2014-09-17)
Metastatic breast cancer is currently incurable, and available therapies are associated with severe toxicities. Induction of protective anti-tumor immunity is a promising therapeutic approach for disseminated breast cancer, as immune responses are (i) systemic; (ii) antigen-specific; and (iii) capable of
Kaliyaperumal Viswanathan et al.
Biosensors & bioelectronics, 61, 200-208 (2014-06-03)
A sensitive method for detecting hydrogen peroxide (H2O2) using rhodamine isocyanide incorporated calcium phosphate nanoparticles (Rho/CaP) was developed. The synthesized nanoparticles were characterized based on transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transformed infrared spectroscopy (FTIR), Raman spectroscopy
Roberta Martinelli et al.
Journal of cell science, 127(Pt 17), 3720-3734 (2014-07-09)
Immune cell trafficking requires the frequent breaching of the endothelial barrier either directly through individual cells ('transcellular' route) or through the inter-endothelial junctions ('paracellular' route). What determines the loci or route of breaching events is an open question with important
Songtao Cai et al.
Chemical communications (Cambridge, England), 49(8), 822-824 (2012-12-14)
A fluorescent chemosensor with high sensitivity and selectivity for palladium species based on a conjugate of phosphine and rhodamine B has been developed. The chemosensor showed an excellent palladium selectivity with a detection limit down to the 10(-9) M range
Andreas Reisch et al.
ACS nano, 9(5), 5104-5116 (2015-04-22)
Ultrasmall polymer nanoparticles are rapidly gaining importance as nanocarriers for drugs and contrast agents. Here, a straightforward modular approach to efficiently loaded and stable sub-20-nm polymer particles is developed. In order to obtain ultrasmall polymer nanoparticles, we investigated the influence
Catherine M Kelso et al.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 36(4), 694-700 (2014-10-14)
Introduction of microperforations in round window membrane (RWM) will allow reliable and predictable intracochlear delivery of pharmaceutical, molecular, or cellular therapeutic agents. Reliable delivery of medications into the inner ear remains a formidable challenge. The RWM is an attractive target
Keon-Joo Lee et al.
Optics express, 23(19), 24903-24909 (2015-09-26)
Whispering gallery modes (WGMs) around the liquid crystal droplets are sensitive to the director orientation at the interface. An electric field was applied for changing the director orientation of a nematic liquid crystal droplet surrounded by polydimethylsiloxane (PDMS), which induced
Bing Cai et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 94, 404-410 (2015-07-02)
To reduce the effort required to penetrate the skin and optimize drug release profiles, bioceramic microneedle arrays with higher-aspect-ratio needles and a flexible and self-swelling substrate have been developed. Swelling of the substrate can assist in separating it from the
Maria Cristina Straccia et al.
Marine drugs, 13(5), 2890-2908 (2015-05-15)
In this work, a coating of chitosan onto alginate hydrogels was realized using the water-soluble hydrochloride form of chitosan (CH-Cl), with the dual purpose of imparting antibacterial activity and delaying the release of hydrophilic molecules from the alginate matrix. Alginate
Atul Bhardwaj et al.
Bioorganic & medicinal chemistry letters, 23(1), 163-168 (2012-12-04)
The observation that the cyclooxygenase-2 (COX-2) isozyme is over-expressed in multiple types of cancer, relative to that in adjacent non-cancerous tissue, prompted this investigation to prepare a group of hybrid fluorescent conjugates wherein the COX inhibitors ibuprofen, (S)-naproxen, acetyl salicylic
Clément Carel et al.
PloS one, 9(5), e97148-e97148 (2014-05-13)
Understanding the mechanism that controls space-time coordination of elongation and division of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is critical for fighting the tubercle bacillus. Most of the numerous enzymes involved in the synthesis of Mycolic acid
Simplifying microfluidic separation devices towards field-detection of blood parasites
Holm SH, et al.
Analytical Methods : Advancing Methods and Applications, 8(16), 3291-3300 (2016)
Tania Gamberi et al.
The international journal of biochemistry & cell biology, 65, 61-71 (2015-05-31)
Auranofin is a gold based drug in clinical use since 1985 for the treatment of rheumatoid arthritis. Beyond its antinflammatory properties, auranofin exhibits other attractive biological and pharmacological actions such as a potent in vitro cytotoxicity and relevant antimicrobial and
Molecular forms of rhodamine B
Arbeloa IL and Ojeda PR
Chemical Physics Letters, 79(2), 347-350 (1981)
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