880135P

应用筛选条件

关键词:'880135P'

显示 1-14 共 14 条结果关于 "880135P" 范围论文

ITGA2 as a potential nanotherapeutic target for glioblastoma

Guo P, et al.

Scientific reports, 9(1), 6195-6195 (2019)

Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma.

Mohammad Mashreghi et al.

Nanoscale research letters, 15(1), 101-101 (2020-05-10)

In this study, we have surface-functionalized PEGylated-nanoliposomal doxorubicin (DOX) with anti-EpCAM (epithelial cell adhesion molecule) aptamer via post-insertion of anti-EpCAM aptamer-conjugated DSPE-mPEG2000 into Caelyx® (ED-lip). The size, charge, release profile, and cytotoxicity and cellular uptake of formulation were determined. The

Carboxylic Acid: Key Role in Life Sciences (2019)

Gold nanocap-supported upconversion nanoparticles for fabrication of a solid-phase aptasensor to detect ochratoxin A.

Kihyeun Kim et al.

Biosensors & bioelectronics, 150, 111885-111885 (2019-11-25)

Solid-phase, single-step biosensors are crucial for the development of portable, reusable, and convenient biosensors, otherwise known as point-of-care (POC) testing. Although high-performance single-step biosensors based on the principle of Förster resonance energy transfer (FRET) and using upconversion nanoparticles (UCNPs) functionalized

Cyclic RGD functionalized liposomes targeted to activated platelets for thrombosis dual-mode magnetic resonance imaging.

Sen Ye et al.

Journal of materials chemistry. B, 8(3), 447-453 (2019-12-14)

Thrombotic disease is a serious threat to human health. The rapid and accurate detection of thrombosis is still a clinical challenge. To achieve the accurate diagnosis of thrombosis with magnetic resonance imaging (MRI), nanomaterials-based contrast agents have been developed in

Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis

Guo P, et al.

Science advances, 5(3), eaav5010-eaav5010 (2019)

In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications

Hua S and Vaughan B

International journal of nanomedicine, 14, 2191-2191 (2019)

Nanoscale characterization of PEGylated phospholipid coatings formed by spray drying on silica microparticles.

Junxue An et al.

Journal of colloid and interface science, 577, 92-100 (2020-05-31)

Phospholipids constitute biocompatible and safe excipients for pulmonary drug delivery. They can retard the drug release and, when PEGylated, also prolong the residence time in the lung. The aim of this work was to assess the structure and coherence of

Dual functional liposomes carrying antioxidants against tau hyperphosphorylation and apoptosis of neurons.

Yung-Chih Kuo et al.

Journal of drug targeting, 28(9), 949-960 (2020-04-28)

Quercetin (QU) and rosmarinic acid (RA) were loaded in phosphatidic acid-liposomes (QU/RA-PA-liposomes) with surface apolipoprotein E (ApoE) using a process of thin-film hydration, followed by covalent crosslinking to activate biological pathways for penetrating the blood-brain barrier (BBB) and redeeming the

Nanoparticle Drug Delivery Can Reduce the Hepatotoxicity of Therapeutic Cargo.

Feifei Yang et al.

Small (Weinheim an der Bergstrasse, Germany), 16(7), e1906360-e1906360 (2020-01-24)

Hepatotoxicity is a key concern in the clinical translation of nanotherapeutics because preclinical studies have consistently shown that nanotherapeutics accumulates extensively in the liver. However, clinical-stage nanotherapeutics have not shown increased hepatotoxicity. Factors that can contribute to the hepatotoxicity of

Complement Receptor Targeted Liposomes Encapsulating the Liver X Receptor Agonist GW3965 Accumulate in and Stabilize Atherosclerotic Plaques.

Naomi Benne et al.

Advanced healthcare materials, 9(10), e2000043-e2000043 (2020-04-25)

Atherosclerosis is characterized by the retention of lipids in foam cells in the arterial intima. The liver X receptor (LXR) agonist GW3965 is a promising therapeutic compound, since it induces reverse cholesterol transport in foam cells. However, hepatic LXR activation

Transferrin-Modified Osthole PEGylated Liposomes Travel the Blood-Brain Barrier and Mitigate Alzheimer's Disease-Related Pathology in APP/PS-1 Mice.

Liang Kong et al.

International journal of nanomedicine, 15, 2841-2858 (2020-05-20)

Osthole (Ost) is a coumarin compound that strengthens hippocampal neurons and neural stem cells against Aβ oligomer-induced neurotoxicity in mice, and is a potential drug for the treatment of Alzheimer's disease (AD). However, the effectiveness of the drug is limited

In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications.

Susan Hua et al.

International journal of nanomedicine, 14, 2191-2206 (2019-04-17)

Targeted intervention to the uterus has great potential for the treatment of obstetric complications (eg, preterm birth, dysfunctional labor, and postpartum hemorrhage) by improving the effectiveness and safety of therapeutic compounds. In particular, targeting the oxytocin receptor (OTR) is a

Lipid-based phagocytosis nanoenhancer for macrophage immunotherapy.

Anujan Ramesh et al.

Nanoscale, 12(3), 1875-1885 (2020-01-07)

Tumor associated macrophages (TAMs) play an important role in initiating the immunosuppressive environment that negatively impacts the immunotherapy efficacy and has long been linked with cancer progression. On the other hand, activated macrophages display immense phagocytic potential and can be

1/1