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Andrea M Spiri et al.
BMC veterinary research, 13(1), 138-138 (2017-05-27)
Leptospirosis is a re-emerging bacterial zoonosis caused by spirochetes of the genus Leptospira. Severe disease has been reported in dogs in Europe despite vaccination with bivalent Leptospira vaccines. Recently, a tetravalent canine Leptospira vaccine (Nobivac® L4) was licenced in Europe.
Chia-Ying Lien et al.
Journal of physiology and biochemistry, 71(4), 669-678 (2015-09-26)
Doxorubicin (DOX) is a potent and widely used antineoplastic agent. Despite the efficacy of DOX, its clinical use is limited by a dose-dependent cardiotoxicity. Chronic exercise training has been shown to protect against DOX-induced cardiotoxicity. It is less clear whether
S Lester et al.
Annals of the rheumatic diseases, 67(6), 849-854 (2007-09-20)
The RCA alpha block (Regulators of Complement Activation, 1q32) contains critical complement regulatory genes such as CR1 and MCP. This study examined RCA alpha block haplotype associations with both disease susceptibility and diversification of the anti-Ro/La autoantibody response in primary
Joshua D Harris et al.
The American journal of sports medicine, 44(1), 20-27 (2015-09-02)
The demands of hip strength and motion in ballet are high. Hip disorders, such as cam and pincer deformities or dysplasia, may affect dance performance. However, the prevalence of these radiographic findings is unknown. To determine the prevalence of radiographic
J Bernier et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 48(2), 123-133 (1998-10-23)
The EORTC has initiated studies to combine nicotinamide with carbogen in accelerated fractionation schedules (ARCON), since for some tumour types, acute and chronic hypoxia as well as treatment protraction may prejudice the outcome of radiotherapy. The tolerable dose of nicotinamide
J M Cox et al.
Infection and immunity, 69(11), 6970-6980 (2001-10-13)
Helicobacter pylori strains containing the cag pathogenicity island (PAI) induce NF-kappaB activation and interleukin-8 secretion in gastric epithelial cells. The aim of this study was to investigate changes in epithelial gene expression induced by cag PAI-positive and -negative strains of
A Bamias et al.
Urology, 62(2), 368-373 (2003-08-02)
To study retrospectively CA 125, CD44, and epithelial membrane antigen (EMA) expression in renal cell carcinoma and their role as prognostic factors. CD44 is a cell adhesion molecule, and CA 125 and EMA are tumor-associated antigens used in the diagnosis
Hajer Battikh et al.
Microbial drug resistance (Larchmont, N.Y.), 23(4), 468-472 (2016-11-02)
In this study, we have attempted to report the first clonal spread of colistin-resistant Klebsiella pneumoniae coproducing KPC and VIM carbapenemases in the neonatal unit of Rabta Teaching Hospital of Tunis (Tunisia). This retrospective study was performed from January 1
N Prajda et al.
Biochemical pharmacology, 37(5), 875-880 (1988-03-01)
The in vivo actions of two antimetabolites, acivicin (NSC-163501) and tiazofurin (NSC-286193), were examined on the enzymic programs of rat bone marrow. From the bone marrow of the femurs, 100,000 g supernatant fractions were prepared; enzymic activities were measured by
Luis R Comolli et al.
Nucleic acids research, 30(20), 4371-4379 (2002-10-18)
The NMR structure of the 3' stem-loop (3'SL) from human U4 snRNA was determined to gain insight into the structural basis for conservation of this stem-loop sequence from vertebrates. 3'SL sequences from human, rat, mouse and chicken U4 snRNA each
Yvonne Bausback et al.
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 24(4), 459-467 (2017-06-01)
To evaluate the performance of the Ranger paclitaxel-coated balloon vs uncoated balloon angioplasty for femoropopliteal lesions. Between January 2014 and October 2015, the prospective, randomized RANGER SFA study ( ClinicalTrials.gov identifier NCT02013193) enrolled 105 patients with symptomatic lower limb ischemia
Sukran Erten et al.
Internal medicine (Tokyo, Japan), 52(3), 339-344 (2013-02-02)
The aim of the present study was to evaluate the plasma vitamin D (vit D) levels and their association with the disease activity in patients with ankylosing spondylitis (AS) and undifferentiated spondyloarthritis (uSpA) compared with healthy populations. This study included
S K Kabra et al.
Indian pediatrics, 40(7), 612-619 (2003-07-26)
To document clinical profile of cystic fibrosis (CF) in Indian children and the prevalence of delta F508 mutation in these patients. Observational study. Pediatric chest clinic in an urban tertiary care center in north India. July 1995 to June 2002.
Takayuki Iwamoto et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 30(7), 729-734 (2012-02-01)
We examined borderline estrogen receptor (ER) -positive cancers, defined as having 1% to 10% positivity by immunohistochemistry (IHC), to determine whether they show the same global gene-expression pattern and high ESR1 mRNA expression as ER-positive cancers or if they are
Ming-Tsang Wu et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 103(5), 337-343 (2004-06-25)
Many epidemiological studies have investigated the relationship between p53 codon 72 polymorphism and cervical cancer risk, but the findings are still conflicting. In contrast, data are lacking on the relationship between XRCC1 polymorphism and cervical neoplasm risk. This community-based nested
D Vyas et al.
Journal of animal science, 93(8), 3950-3958 (2015-10-07)
The objective of this study was to determine whether supplementing organic acids can prevent incidences of subacute ruminal acidosis (SARA) in beef heifers fed a diet consisting of 8% barley silage and 92% barley grain-based concentrate (DM basis). Ten ruminally
T Mentzel et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 25(1), 75-85 (2011-09-13)
Postradiation cutaneous vascular lesions after treatment of breast carcinoma comprise a heterogeneous group of benign, atypical, and malignant lesions and are best regarded as points along a morphological spectrum. We analyzed a series of cutaneous angiosarcomas after treatment of breast
X P Yu et al.
Endocrinology, 138(8), 3085-3092 (1997-08-01)
Osteocalcin (OC) is a bone-specific extracellular matrix protein expressed by mature osteoblasts during late stages of differentiation. Previous studies have shown that forskolin, an activator of adenylate cyclase, stimulated OC production. Because PTH has been shown to activate several intracellular
J K Czop et al.
Journal of immunology (Baltimore, Md. : 1950), 135(5), 3388-3393 (1985-11-01)
The glycans used in an earlier study to define the ligand specificity of the human monocyte phagocytic receptor for unopsonized particulate activators were assessed for their capacities to activate the proteins of the human alternative complement pathway. Normal human serum
Miguel Mendivil-Perez et al.
Anti-cancer drugs, 26(6), 583-598 (2015-03-04)
In this study, we investigated the molecular mechanism of doxorubicin (dxr)-induced cytotoxicity on Jurkat cells - a model cell of human acute lymphoblastic leukemia - under normoxic (20% O2) and hypoxic (5% O2) conditions. Using in-cell western analysis, immunofluorescence, flow
Thomas J H Volman et al.
Shock (Augusta, Ga.), 17(6), 468-472 (2002-06-19)
The purpose of the study was to investigate the course of the zymosan-induced multiple organ dysfunction syndrome (MODS) in the absence of tumor necrosis factor (TNF) in a murine model. Tumor Necrosis Factor-alpha-lymphotoxin-a knockout (TNF/LT-/-) mice (n = 36) and
John A Rooke et al.
The British journal of nutrition, 112(3), 398-407 (2014-05-02)
The aims of the present study were to quantify hydrogen (H2) and methane (CH4) emissions from beef cattle under different dietary conditions and to assess how cattle genotype and rumen microbial community affected these emissions. A total of thirty-six Aberdeen
A R Mackay et al.
Laboratory investigation; a journal of technical methods and pathology, 70(6), 800-806 (1994-06-01)
Based on a previous observation of laminin-mediated increase in type IV collagenolytic activity of human melanoma (A-2058) and fibrosarcoma (HT-1080) cell lines (Turpeenniemi-Hujanen T, et al. Laminin increases the release of type IV collagenase from malignant cells. J Biol Chem
Stefan D Anker et al.
European journal of heart failure, 17(10), 1050-1056 (2015-05-27)
Hyperkalaemia in heart failure patients limits use of cardioprotective renin-angiotensin-aldosterone system inhibitors (RAASi). Sodium zirconium cyclosilicate (ZS-9) is a selective potassium ion trap, whose mechanism of action may allow for potassium binding in the upper gastrointestinal tract as early as
Akira Tsuburaya et al.
The Lancet. Oncology, 15(8), 886-893 (2014-06-24)
The prognosis for locally advanced gastric cancer is poor despite advances in adjuvant chemotherapy. We did the Stomach cancer Adjuvant Multi-Institutional group Trial (SAMIT) to assess the superiority of sequential treatment (paclitaxel then tegafur and uracil [UFT] or paclitaxel then
Gunter von Minckwitz et al.
The Lancet. Oncology, 15(7), 747-756 (2014-05-06)
Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, trastuzumab, and a platinum salt for HER2-positive breast cancer. We therefore aimed to assess the efficacy
Xiang Ao et al.
Clinical orthopaedics and related research, 477(6), 1492-1504 (2019-05-17)
Intervertebral disc degeneration is a major cause of chronic low back pain, and excessive loading contributes to intervertebral disc degeneration. However, the lack of an effective bipedal in vivo animal model limits research about this condition. To evaluate the utility
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
Bhavan Prasad Rai et al.
The Cochrane database of systematic reviews, 4, CD011903-CD011903 (2019-04-25)
It has been suggested that in comparison with open radical cystectomy, robotic-assisted radical cystectomy results in less blood loss, shorter convalescence, and fewer complications with equivalent short-term oncological and functional outcomes; however, uncertainty remains as to the magnitude of these
Jacqueline Dinnes et al.
The Cochrane database of systematic reviews, 12, CD011902-CD011902 (2018-12-07)
Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. Although history-taking and visual inspection of a suspicious
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