93-61-8

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Association between human leukocyte antigen-G genotype and success of in vitro fertilization and pregnancy outcome.

T V F Hviid et al.

Tissue antigens, 64(1), 66-69 (2004-06-12)

To determine if a 14-bp deletion/insertion polymorphism in the 3'-untranslated region of exon 8 of the gene encoding human leukocyte antigen (HLA)-G in a homozygous form is associated with repeated, unsuccessful in vitro fertilization (IVF) treatments, and with increased risk

Oral miltefosine for Indian post-kala-azar dermal leishmaniasis: a randomised trial.

Shyam Sundar et al.

Tropical medicine & international health : TM & IH, 18(1), 96-100 (2012-11-10)

Standard treatment of Indian post-kala-azar dermal leishmaniasis (PKDL) is unsatisfactory because to achieve therapeutic effectiveness, heroic courses of parenteral and toxic agents have to be administered. Our objective was to evaluate oral miltefosine for its potential to provide effective as

[Expression pattern and clinical significance of hairy enhancer of split 1 in colorectal cancer].

Hei-ying Jin et al.

Zhonghua yi xue za zhi, 91(41), 2891-2894 (2012-02-16)

To explore the roles of hairy enhancer of split 1 (Hes1) gene in colorectal cancer and analyze its clinical significance. A total of 146 cases with colorectal cancer at our hospital were collected prospectively and followed up. There were 84

The natural history of hereditary pancreatitis: a national series.

V Rebours et al.

Gut, 58(1), 97-103 (2008-08-30)

The prevalence and natural history of hereditary pancreatitis (HP) remain poorly documented. The aims of this study were to assess genetic, epidemiological, clinical and morphological characteristics of HP in an extensive national survey. A cohort comprising all HP patients was

Effects of ginger constituents on the gastrointestinal tract: role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors.

Heinz H Pertz et al.

Planta medica, 77(10), 973-978 (2011-02-10)

The herbal drug ginger (Zingiber officinale Roscoe) may be effective for treating nausea, vomiting, and gastric hypomotility. In these conditions, cholinergic M (3) receptors and serotonergic 5-HT (3) and 5-HT (4) receptors are involved. The major chemical constituents of ginger

Expression of p73 and c-Abl proteins in human ovarian carcinomas.

Maynur Niyazi et al.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 70(3), 234-242 (2003-08-21)

The p73, a homologue of the p53 tumor suppressor protein, has a pro-apoptotic activity which is induced by the c-Abl, a protein tyrosine kinase appearing in the nucleus and cytoplasm of proliferating cells. However, the role of p73 and c-Abl

Point-of-care hemostasis in children with congenital heart disease, the POCHEMO study: baseline reference values of thromboelastometry and impedance aggregometry.

David Longchamp et al.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 30(5), 199-204 (2019-06-04)

: Viscoelastic tests and impedance aggregometry allow coagulation evaluation at the bedside, but reference values are scarce in pediatrics. The aim of this study was to establish reference values of thromboelastometry and impedance aggregometry for this population and compare it

Chicken deoxyribonuclease: purification, characterization, gene cloning and gene expression.

Chi-Chao Hu et al.

Journal of protein chemistry, 22(1), 41-49 (2003-05-13)

Chicken DNase was purified to apparent homogeneity from the pancreas extract. It showed two isoforms, A and B forms, on cation-exchange chromatography. On SDS-PAGE it was a 30-kDa protein. When analyzed on an electrospray-mass analyzer, form A showed a major

Mutation of keratin 8 in patients with liver disease.

Maximilian Schöniger-Hekele et al.

Journal of gastroenterology and hepatology, 21(9), 1466-1469 (2006-08-17)

Epithelial tissues of the gastrointestinal tract and the liver express predominantly cytokeratin 8 and cytokeratin 18. In vitro experiments and animal studies have demonstrated a protective influence of keratin 8 and keratin 18 against toxic damage of hepatocytes. A specific

Mutation spectrum of the dystrophin gene in 442 Duchenne/Becker muscular dystrophy cases from one Japanese referral center.

Yasuhiro Takeshima et al.

Journal of human genetics, 55(6), 379-388 (2010-05-21)

Recent developments in molecular therapies for Duchenne muscular dystrophy (DMD) demand accurate genetic diagnosis, because therapies are mutation specific. The KUCG (Kobe University Clinical Genetics) database for DMD and Becker muscular dystrophy is a hospital-based database comprising 442 cases. Using

Pilot Study of Bortezomib and Dexamethasone Pre- and Post-Risk-Adapted Autologous Stem Cell Transplantation in AL Amyloidosis.

Heather Landau et al.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 26(1), 204-208 (2019-08-26)

Treatment for AL amyloidosis aims to eradicate clonal plasma cells, thereby disrupting the amyloid deposition causing organ damage. Risk-adapted high-dose melphalan plus autologous stem cell transplantation (RA-ASCT) is an effective therapy. We conducted a prospective pilot analysis of a comprehensive

Germline BRCA mutations are associated with higher risk of nodal involvement, distant metastasis, and poor survival outcomes in prostate cancer.

Elena Castro et al.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 31(14), 1748-1757 (2013-04-10)

To analyze the baseline clinicopathologic characteristics of prostate tumors with germline BRCA1 and BRCA2 (BRCA1/2) mutations and the prognostic value of those mutations on prostate cancer (PCa) outcomes. This study analyzed the tumor features and outcomes of 2,019 patients with

Reducing the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis using 4-Fr pancreatic plastic stents placed with common-type guidewires: Results from a prospective multinational registry.

Nadav Sahar et al.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 31(3), 299-306 (2018-12-07)

Pancreatic plastic stents (PPS) can reduce the risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP). Prospective multicenter documentation of PEP rate after PPS placement is scarce. A new 4-Fr stent designed to be deployed over a 0.035-inch guidewire was used to

Overexpression of KIAA0101 predicts high stage, early tumor recurrence, and poor prognosis of hepatocellular carcinoma.

Ray-Hwang Yuan et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 13(18 Pt 1), 5368-5376 (2007-09-19)

KIAA0101 is a proliferating cell nuclear antigen-associated factor and involved in cell proliferation. This study is to elucidate its role in the progression, early tumor recurrence (ETR), and prognosis of hepatocellular carcinoma (HCC). KIAA0101 mRNA was measured by reverse transcription-PCR

J Weisser-Thomas et al.

Journal of pharmacological and toxicological methods, 51(2), 91-103 (2005-03-16)

Adenovirus-mediated gene transfer into cardiomyocytes has emerged as an interesting tool to study functional effects of single proteins. However, the functional consequences of cell isolation, cell culture per se and adenovirus-mediated transfer of the LacZ or SERCA1 gene in failing

Lamotrigine XR conversion to monotherapy: first study using a historical control group.

Jacqueline A French et al.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 9(1), 176-184 (2011-12-06)

The efficacy and safety of lamotrigine extended-release tablets (LTG XR) as monotherapy for partial seizures were evaluated using the conversion-to-monotherapy design, and historical data as the control. This methodology was recently approved by the United States Food and Drug Administration

Endophthalmitis caused by streptococcal species: clinical settings, microbiology, management, and outcomes.

Ajay E Kuriyan et al.

American journal of ophthalmology, 157(4), 774-780 (2014-01-15)

To report the clinical settings, antibiotic susceptibilities, and outcomes of endophthalmitis caused by Streptococcus species. Retrospective, observational case series. Single-center study evaluating all patients with culture-positive endophthalmitis caused by Streptococcus species between January 1, 2000, and December 31, 2011. Study

Results of a prospective, randomized, multicenter study evaluating sacral neuromodulation with InterStim therapy compared to standard medical therapy at 6-months in subjects with mild symptoms of overactive bladder.

Steven Siegel et al.

Neurourology and urodynamics, 34(3), 224-230 (2014-01-15)

This prospective, randomized, multicenter trial evaluated the 6-month success rate of sacral neuromodulation (SNM) with InterStim® Therapy versus standard medical therapy (SMT) for overactive bladder (OAB). Enrolled subjects discontinued OAB medications prior to and during baseline data collection and were

Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristics.

Jonine D Figueroa et al.

Breast cancer research and treatment, 121(3), 727-735 (2009-11-26)

The transforming growth factor beta (TGF-beta) pathway can play either a tumor-suppressing or a tumor-promoting role in human breast carcinogenesis. In order to determine whether expression of TGF-beta signaling factors varies by age at onset and breast tumor characteristics that

Luteal phase support with decapeptyl improves pregnancy outcomes in intracytoplasmic sperm injection with higher basal follicle-stimulating hormone or lower mature oocytes.

Hsiao-Fan Kung et al.

Journal of the Chinese Medical Association : JCMA, 77(10), 524-530 (2014-08-28)

The role of midluteal phase gonadotropin-releasing hormone (GnRH) agonist had been an issue of debate. The aim of this retrospective study was to evaluate the effect of a mid-luteal phase GnRH agonist as an additional luteal phase support (LPS) in

Effect of experimental elevation of free fatty acids on insulin secretion and insulin sensitivity in healthy carriers of the Pro12Ala polymorphism of the peroxisome proliferator--activated receptor-gamma2 gene.

N Stefan et al.

Diabetes, 50(5), 1143-1148 (2001-05-04)

The transcription of many genes involved in lipid metabolism is regulated by the peroxisome proliferator-activated receptor-gamma (PPAR-gamma). The Pro12Ala polymorphism in the PPAR-gamma2 gene has been associated with reduced transcriptional activity in vitro and increased insulin sensitivity in vivo. Although

Phase II study evaluating 2 dosing schedules of oral foretinib (GSK1363089), cMET/VEGFR2 inhibitor, in patients with metastatic gastric cancer.

Manish A Shah et al.

PloS one, 8(3), e54014-e54014 (2013-03-22)

The receptors for hepatocyte and vascular endothelial cell growth factors (MET and VEGFR2, respectively) are critical oncogenic mediators in gastric adenocarcinoma. The purpose is to examine the safety and efficacy of foretinib, an oral multikinase inhibitor targeting MET, RON, AXL

Daylight photodynamic therapy for actinic keratoses: a randomized double-blinded nonsponsored prospective study comparing 5-aminolaevulinic acid nanoemulsion (BF-200) with methyl-5-aminolaevulinate.

N Neittaanmäki-Perttu et al.

The British journal of dermatology, 171(5), 1172-1180 (2014-08-12)

Daylight-mediated photodynamic therapy (DL-PDT) using methyl-5-aminolaevulinate (MAL) is effective for thin, grade I, actinic keratoses (AK). There are no published studies of other photosensitizers used in DL-PDT. To compare the efficacy and adverse effects of 5-aminolaevulinic acid nanoemulsion (BF-200 ALA)

Loss of INI1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma.

Jason L Hornick et al.

The American journal of surgical pathology, 33(4), 542-550 (2008-11-27)

INI1 (hSNF5/SMARCB1), a member of the SWI/SNF chromatin remodeling complex located on chromosome 22q11.2, is deleted or/or mutated in strictly defined malignant rhabdoid tumors (MRT) of infancy. Recent studies suggest that some epithelioid sarcomas (ES) also show inactivation of INI1.

Sympathetic Vasoconstrictor Responsiveness of the Leg Vasculature During Experimental Endotoxemia and Hypoxia in Humans.

Patrice Brassard et al.

Critical care medicine, 44(4), 755-763 (2015-11-21)

Sympathetic vasoconstriction regulates peripheral circulation and controls blood pressure, but sepsis is associated with hypotension. We evaluated whether apparent loss of sympathetic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxia. Prospective descriptive study. Hospital research laboratory.

Vertical small scale variations of sorption and mineralization of three herbicides in subsurface limestone and sandy aquifer.

G S Janniche et al.

Journal of contaminant hydrology, 123(3-4), 167-177 (2011-02-16)

Vertical variation in sorption and mineralization potential of mecoprop (MCPP), isoproturon and acetochlor were investigated at low concentrations (μg-range) at the cm-scale in unsaturated sub-surface limestone samples and saturated sandy aquifer samples from an agricultural catchment in Brévilles, France. From

Tumours of histiocytes and accessory dendritic cells: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases.

S A Pileri et al.

Histopathology, 41(1), 1-29 (2002-07-18)

Neoplasms of histiocytes and dendritic cells are rare, and their phenotypic and biological definition is incomplete. Seeking to identify antigens detectable in paraffin-embedded sections that might allow a more complete, rational immunophenotypic classification of histiocytic/dendritic cell neoplasms, the International Lymphoma

Genome-Wide Analysis of the NAC Transcription Factor Gene Family Reveals Differential Expression Patterns and Cold-Stress Responses in the Woody Plant Prunus mume.

Xiaokang Zhuo et al.

Genes, 9(10) (2018-10-17)

NAC transcription factors (TFs) participate in multiple biological processes, including biotic and abiotic stress responses, signal transduction and development. Cold stress can adversely impact plant growth and development, thereby limiting agricultural productivity. Prunus mume, an excellent horticultural crop, is widely

Platelet function testing in transient ischaemic attack and ischaemic stroke: A comprehensive systematic review of the literature.

Soon Tjin Lim et al.

Platelets, 26(5), 402-412 (2015-06-05)

The majority of patients with ischaemic cerebrovascular disease (CVD) are not protected from further vascular events with antiplatelet therapy. Measurement of inhibition of platelet function ex vivo on antiplatelet therapy, using laboratory tests that correlate with the clinical effectiveness of

Xpert MTB/RIF Ultra for the diagnosis of HIV-associated tuberculous meningitis: a prospective validation study.

Fiona V Cresswell et al.

The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)

Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid

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