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关键词:'93-91-4'
显示 1-30 共 52 条结果 关于 "93-91-4" 范围 论文
Yan Xiong et al.
Biochemistry, 45(7), 2322-2332 (2006-02-16)
4-Azido-2-hydroxybenzoic acid (4-AzHBA), a novel photoactive benzoic acid derivative, has been synthesized and used as a photoprobe to identify the phenol binding site of UDP-glucuronosyltransferases (UGTs). Analysis of recombinant His-tag UGTs from the 1A family for their ability to glucuronidate
Mariana Fonseca Xisto et al.
Diagnostics (Basel, Switzerland), 10(6) (2020-06-11)
Dengue is one of the major diseases causing global public health concerns. Despite technological advances in vaccine production against all its serotypes, it is estimated that the dengue virus is responsible for approximately 390 million infections per year. Laboratory diagnosis
S M Abdel-Rahman et al.
American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 56(3), 243-245 (1999-02-25)
The stability of terbinafine 25 mg/mL (as the hydrochloride salt) in an extemporaneously prepared oral suspension at 25 and 4 degrees C was studied. Twenty 250-mg terbinafine tablets were crushed to a fine powder and diluted to a concentration of
J R Huizenga et al.
Molecular and chemical neuropathology, 34(2-3), 169-177 (1999-05-18)
We have determined ammonia in cerebrospinal fluid (CSF) with the indophenol direct method. The results were compared with an enzymatic method. The method is very simple, and precision (coefficient of variation 1.6%) and linearity (r = 0.9999, p < 0.001)
F Dequiedt et al.
DNA sequence : the journal of DNA sequencing and mapping, 5(4), 261-264 (1995-01-01)
The bovine p53 open reading frame was cloned and characterized using a reverse transcription-polymerase chain reaction amplification (RT-PCR) method. After sequencing, it appeared that this cDNA is able to code for a 386 amino acids protein with high degree of
Tiago Cardoso Alves et al.
NMR in biomedicine, 21(4), 337-344 (2007-08-09)
The gluconeogenic contribution to glucose production in livers isolated from rats fasted for 24 h was determined by 13C-NMR isotopomer distribution analysis of secreted glucose enriched from 99% [13C]bicarbonate (n = 4) and 99% [1-13C]lactate (n = 4). Experiments with
S R Lehrman et al.
International journal of peptide and protein research, 31(6), 544-554 (1988-06-01)
Equine prolactin was determined to be a single chain protein of 199 amino acid containing two tryptophan and six cysteine residues, as found in other mammalian prolactins. The primary sequence of equine prolactin was obtained by automated Edman analyses of
X Xu et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 9(8), 781-786 (2000-08-22)
Isoflavones are soy phytoestrogens that have been suggested to be anticarcinogenic. Our previous study in premenopausal women suggested that the mechanisms by which isoflavones exert cancer-preventive effects may involve modulation of estrogen metabolism away from production of potentially carcinogenic metabolites
Hanna Lehto et al.
World neurosurgery, 82(5), 702-713 (2014-06-18)
Aneurysms of the posterior inferior cerebellar artery (PICA) distal to its origin are rare. Beside their rarity, their treatment is challenged by a high proportion of fusiform aneurysms, torturous course of PICA, and often severe bleeding. Our aim is to
Danette J Nicolay et al.
Cellular and molecular neurobiology, 24(3), 357-366 (2004-06-23)
1. Although recent advances have provided insight into the transcriptional control of oligodendrocyte (OG) development, little information exists on the role of clustered Hox genes in this process. The aim of this study was to examine the expression profile of
Fatma Gassara-Chatti et al.
Food chemistry, 137(1-4), 18-24 (2012-12-04)
The thermal stability, physico-chemical properties and effect on juice clarification of hydrogel formulations of ligninolytic enzymes from Phanerochaete chrysosporium were evaluated. The results showed that enzyme entrapment increase significantly (P<0.05) the thermal stability of enzymes at 4 and 75 °C.
Michael P Manns et al.
Gastroenterology, 147(2), 366-376 (2014-04-15)
MK-5172 is an inhibitor of the hepatitis C virus (HCV) nonstructural protein 3/4A protease; MK-5172 is taken once daily and has a higher potency and barrier to resistance than licensed protease inhibitors. We investigated the efficacy and tolerability of MK-5172
Mika Sugai et al.
Pathology international, 58(11), 681-686 (2008-10-11)
Hepatocyte nuclear factor 4 alpha (HNF4 alpha) is a member of the nuclear receptor superfamily and is expressed in several endodermal tissues. The aim of the present study was to examine the expression of HNF4 alpha on ovarian epithelial tumors
Brahmam Pujala et al.
The Journal of organic chemistry, 76(21), 8768-8780 (2011-09-09)
The scope and limitations of metal tetrafluoroborates have been studied for epoxide ring-opening reaction with amines, and Zn(BF(4))(2)·xH(2)O has been found to be a mild and efficient catalyst affording high yields under solvent-free conditions at rt with excellent chemo-, regio-
Daniela Gustinucci et al.
Acta cytologica, 56(5), 506-514 (2012-10-19)
We evaluated the performance of cytologic p16(INK4a) (p16) immunostaining within a cervical cancer screening program for the categories of atypical squamous cells of undetermined significance (ASC-US) and low-grade squamous intraepithelial lesion (LS after triage with high-risk human papillomavirus (HR-HPV) testing
Georg H H Borner et al.
The Journal of cell biology, 197(1), 141-160 (2012-04-05)
Despite recent advances in mass spectrometry, proteomic characterization of transport vesicles remains challenging. Here, we describe a multivariate proteomics approach to analyzing clathrin-coated vesicles (CCVs) from HeLa cells. siRNA knockdown of coat components and different fractionation protocols were used to
Georg H H Borner et al.
The Journal of cell biology, 197(1), 141-160 (2012-04-05)
Despite recent advances in mass spectrometry, proteomic characterization of transport vesicles remains challenging. Here, we describe a multivariate proteomics approach to analyzing clathrin-coated vesicles (CCVs) from HeLa cells. siRNA knockdown of coat components and different fractionation protocols were used to
Deepa R J Arachchillage et al.
British journal of haematology, 184(5), 808-816 (2018-12-06)
This retrospective study investigated the efficacy and safety of prothrombin complex concentrates (PCCs) for management of major bleeding events (MBE) in 344 patients receiving the anticoagulants rivaroxaban, apixaban or warfarin during the period January 2016 to April 2018. Median (range)
Chloe E H Scott et al.
The bone & joint journal, 102-B(6), 716-726 (2020-06-02)
This study aims to determine the proportion of patients with end-stage knee osteoarthritis (OA) possibly suitable for partial (PKA) or combined partial knee arthroplasty (CPKA) according to patterns of full-thickness cartilage loss and anterior cruciate ligament (ACL) status. A cross-sectional
S M Miescher et al.
Vox sanguinis, 109(1), 71-78 (2015-03-15)
To evaluate standard intravenous immunoglobulin (IVIG) as an alternative to intravenous cytomegalovirus hyperimmune immunoglobulin (CMVIG) for prophylaxis and therapy of cytomegalovirus (CMV) disease, we measured the ELISA and neutralizing titres of CMV-specific antibodies in CMVIG and IVIG preparations. Anti-CMV-IgG ELISA
Stefan Zeuzem et al.
The New England journal of medicine, 370(21), 1993-2001 (2014-05-06)
In clinical trials, treatment with a combination of the nucleotide polymerase inhibitor sofosbuvir and the antiviral drug ribavirin was associated with high response rates among patients with hepatitis C virus (HCV) genotype 2 infection, with lower response rates among patients
Paul J Devlin et al.
The Journal of thoracic and cardiovascular surgery, 159(4), 1493-1503 (2019-11-02)
To analyze outcomes after pulmonary artery banding (PAB) in complete atrioventricular septal defect (AVSD), with a focus on surgical pathway outcome and timing, survival, and atrioventricular valve function. PAB was performed in 50 of 474 infants (11%) from 28 institutions
Fiona V Cresswell et al.
The Lancet. Infectious diseases, 20(3), 308-317 (2020-01-12)
Tuberculous meningitis accounts for 1-5% of tuberculosis cases. Diagnostic delay contributes to poor outcomes. We evaluated the performance of the new Xpert MTB/RIF Ultra (Xpert Ultra) for tuberculous meningitis diagnosis. In this prospective validation study, we tested the cerebrospinal fluid
P Clapés et al.
Journal of biotechnology, 15(4), 323-338 (1990-09-01)
Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in
Mami Taniuchi et al.
Journal of clinical microbiology, 53(1), 206-211 (2014-11-08)
Amid polio eradication efforts, detection of oral polio vaccine (OPV) virus in stool samples can provide information about rates of mucosal immunity and allow estimation of the poliovirus reservoir. We developed a multiplex one-step quantitative reverse transcription-PCR (qRT-PCR) assay for
A Martini et al.
Journal of viral hepatitis, 22(10), 800-808 (2015-01-23)
Nonalcoholic steatohepatitis (NASH) enhances the risk of progressive liver disease. In chronic hepatitis C (CHC), liver steatosis is frequent, especially in genotype 3, but its clinical significance is debated. As squamous cell carcinoma antigen (SCCA)-IgM has been associated with advanced
Bernd Krüger et al.
Journal of the American Society of Nephrology : JASN, 13(10), 2585-2589 (2002-09-20)
Among the factors modulating transplant rejection and cardiovascular disease, chemokines and their respective receptors deserve special attention. In this respect, increased expression of MCP-1 and the corresponding receptor CCR2 have been demonstrated in renal transplant rejection and coronary artery disease.
Paul Roepman et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 15(22), 7003-7011 (2009-11-06)
The level of estrogen receptor (ER), progesterone receptor (PR), and HER2 aids in the determination of prognosis and treatment of breast cancer. Immunohistochemistry is currently the predominant method for assessment, but differences in methods and interpretation can substantially affect the
Martin Köbel et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 35(5), 430-441 (2016-03-15)
There are 5 major histotypes of ovarian carcinomas. Diagnostic typing criteria have evolved over time, and past cohorts may be misclassified by current standards. Our objective was to reclassify the recently assembled Canadian Ovarian Experimental Unified Resource and the Alberta
Scott J C Pallett et al.
The Lancet. Respiratory medicine, 8(9), 885-894 (2020-07-28)
Health-care workers constitute a high-risk population for acquisition of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Capacity for acute diagnosis via PCR testing was limited for individuals with mild to moderate SARS-CoV-2 infection in the early phase of the
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