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93-98-1

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关键词:'93-98-1'
显示 1-30 共 111 条结果 关于 "93-98-1" 范围 论文
S Piekkola et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 29(6), 962-971 (2012-03-02)
Mycotoxins such as the aflatoxins and deoxynivalenol (DON) are frequent contaminants of food. Aflatoxin B1 (AFB1) and DON affect the immune system and restrict growth; additionally AFB1 is carcinogenic. To date there are limited descriptive biomarker data concerning maternal exposures
N Mori et al.
Gene, 45(3), 275-280 (1986-01-01)
A clone containing cDNA for X chromosome-linked phosphoglycerate kinase (PGK-1) was isolated from a mouse myeloma cDNA library. The nucleotide (nt) sequence of the cDNA has been determined, and the amino acid (aa) sequence of the enzyme thereby deduced. At
W H Boesten et al.
Organic letters, 3(8), 1121-1124 (2001-05-12)
[reaction: see text]. Diastereoselective Strecker reactions based on (R)-phenylglycine amide as chiral auxiliary are reported. The Strecker reaction is accompanied by an in situ crystallization-induced asymmetric transformation, whereby one diastereomer selectively precipitates and can be isolated in 76-93% yield and
Yohan Park et al.
Organic letters, 11(16), 3738-3741 (2009-07-29)
An efficient enantioselective synthetic method for (S)-alpha-alkyl-alpha,beta-diaminopropionic acid is reported. The asymmetric phase-transfer catalytic alkylation of N(1)-Boc-2-phenyl-2-imidazoline-4-carboxylic acid tert -butyl ester in the presence of chiral quaternary ammonium catalyst gave the corresponding alkylated products (93-98% ee) which could be transformed
Min Zhou et al.
Chinese medical journal, 117(10), 1481-1484 (2004-10-23)
There are many candidate genes for chronic obstructive pulmonary disease (COPD). Matrix metalloproteinase-9 (MMP-9) plays an essential role in tissue remodeling and repair associated with development of COPD. In this study we investigated the correlation between MMP-9 gene polymorphism and
Michael J Huvard et al.
Transfusion, 52(5), 1106-1111 (2011-11-02)
The human neutrophil antigen-3 (HNA-3) epitopes reside on the choline transporter-like protein-2 (CTL2). A single-nucleotide substitution (461G>A; Arg154Gln) on the CTL2 gene (SLC44A2) defines the allele SLC44A2*1, which expresses HNA-3a, and SLC44A2*2, which expresses HNA-3b; an additional substitution (457C>T; Leu153Phe)
Pramil N Singh et al.
Asia-Pacific journal of public health, 25(5 Suppl), 45S-53S (2013-05-23)
The validity of survey measures of smoked and smokeless tobacco use in the Western Pacific Region is often unknown. We conducted a validation study (n = 201) in a random sample of rural adults in Cambodia. A comparison with salivary
B Plougastel et al.
Genomics, 23(1), 278-281 (1994-09-01)
The human EWS gene encodes a putative RNA binding protein. As a result of acquired chromosome rearrangement, the N-terminal portion of the EWS protein is fused to the DNA binding domain of either FLI-1 or ERG in the Ewing family
Mark S Sulkowski et al.
The New England journal of medicine, 370(3), 211-221 (2014-01-17)
All-oral combination therapy is desirable for patients with chronic hepatitis C virus (HCV) infection. We evaluated daclatasvir (an HCV NS5A replication complex inhibitor) plus sofosbuvir (a nucleotide analogue HCV NS5B polymerase inhibitor) in patients infected with HCV genotype 1, 2
Carmela De Marco et al.
PloS one, 8(2), e55362-e55362 (2013-02-15)
The phosphatidylinositol 3-kinase (PI3K)/AKT pathway is activated in multiple cancers including ovarian carcinoma (OC). However, the relative contribution of the single components within the PI3K pathway to AKT activation in OC is still unclear. We examined 98 tumor samples from
Netta Nir et al.
Applied microbiology and biotechnology, 78(4), 659-667 (2008-01-23)
The asymmetric bio-reduction of 4-chloro-acetoacetic-acid-ethyl-ester to the pharmaceutical building block (S)-4-chloro-3-hydroxybutanoate-ethyl-ester requires the utilization of an enantioselective robust biocatalyst. Some of the natural Saccharomyces cerevisiae strains, isolated from Mount Carmel National Park in Israel, were characterized as resistant to environmental
E Neufeld et al.
Journal of chromatography. B, Biomedical sciences and applications, 718(2), 273-277 (1998-12-05)
Corticosteroids containing a C21 primary hydroxyl group were derivatised with 9-anthroyl cyanide. The reagent was prepared as a solution in acetonitrile, containing 0.1% triethylamine, at a concentration of 2 mg/ml. Approximately 1 microg of corticosteroid was reacted with 100 microl
O Pohl et al.
Journal of clinical pharmacy and therapeutics, 40(3), 328-332 (2015-04-23)
To treat preterm labour, antenatal corticosteroids and tocolytics are often co-administered. OBE001 is an orally active oxytocin receptor antagonist under development for preterm labour treatment. Co-administration of OBE001 and betamethasone to determine pharmacokinetic interactions was studied during an open-label, randomized
C B'Hymer et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 802(2), 361-366 (2004-03-17)
An accurate and precise method was developed for the detection and quantification of 3-bromopropionic acid (3-BPA), a metabolite and biomarker for exposure to 1-bromopropane (1-BP). 1-BP is used as an industrial solvent and exposure is a health concern for industrial
Melita Lončarić et al.
Current organic synthesis, 17(2), 98-108 (2020-05-19)
In order to preserve the environment from harmful organic solvents, a synthesis of coumarin derivatives was performed in deep eutectic solvents, which are considered as "green" due to their characteristics. Choline chloride based deep eutectic solvents (DESs) were employed, both
Andrei A Raibekas et al.
Biochemistry, 44(29), 9871-9879 (2005-07-20)
Highly concentrated human recombinant interleukin-1 receptor antagonist (IL-1ra) aggregates at elevated temperature without perturbation in its secondary structure. The protein aggregation can be suppressed depending on the buffer ionic strength and the type of anion present in the sample solution.
Mani Shankar Bhattacharyya et al.
New biotechnology, 29(3), 359-364 (2011-08-13)
Sixteen organic co-solvents were screened for stereoselective reduction of 1-acetonapthone in aqueous media by whole cells of Geotrichum candidum. Benzyl alcohol was found to be a good co-solvent as it afforded a high coversion and reduced deactivation of the cells.
V Bazil et al.
Folia biologica, 35(5), 289-297 (1989-01-01)
Monoclonal antibodies against several human leucocyte cell surface antigens were prepared and characterized: (1) MEM-56, MEM-93, MEM-66, and MEM-104 against the CD45R antigen (220 kDa and 205 kDa mol. wt. forms of the leucocyte common antigen CD45 expressed on B-lymphocytes
Yun Wei et al.
Journal of chromatography. A, 1218(36), 6206-6211 (2011-02-19)
Flaveria bidentis (L.) Kuntze is an annual alien weed of Flaveria Juss. (Asteraceae) in China. Bioactive compounds, mainly flavonol glycosides and flavones from F. bidentis (L.) Kuntze, have been studied in order to utilize this invasive weed, Analytical high-performance counter-current
Russell Vang et al.
The American journal of surgical pathology, 36(3), 443-453 (2012-01-17)
Distinction of hydatidiform moles (HMs) from nonmolar specimens (NMs) and subclassification of HMs as complete hydatidiform moles (CHMs) and partial hydatidiform moles (PHMs) are important for clinical practice and investigational studies; yet, diagnosis based solely on morphology is affected by
Steven W Jin et al.
Virology, 530, 39-50 (2019-02-20)
HIV-1 Nef modulates the activation state of CD4+ T cells by altering signaling events elicited by the T cell receptor (TCR). Primary nef sequences exhibit extensive inter-individual diversity that influences their ability to downregulate CD4 and HLA class I; however
Vera Alves et al.
Journal of chromatography. A, 1408, 30-40 (2015-07-21)
A powerful and sensitive method, by microextraction packed sorbent (MEPS), and ultra-high performance liquid chromatography (UHPLC) with a photodiode array (PDA) detection, is described for the determination of fluoxetine, clomipramine and their active metabolites in human urine samples. The MEPS
Jagruti Desai et al.
Colloids and surfaces. B, Biointerfaces, 175, 143-149 (2018-12-12)
The present work aimed to formulate Darunavir loaded lipid nanoemulsion to increase its oral bioavailability and enhance brain uptake. Various batches of lipid nanoemulsion of Darunavir were prepared by high pressure homogenization using soya bean oil, egg lecithin and Tween
Hei-ying Jin et al.
Zhonghua yi xue za zhi, 91(41), 2891-2894 (2012-02-16)
To explore the roles of hairy enhancer of split 1 (Hes1) gene in colorectal cancer and analyze its clinical significance. A total of 146 cases with colorectal cancer at our hospital were collected prospectively and followed up. There were 84
Simone Angeloni et al.
Journal of mass spectrometry : JMS, 53(9), 842-848 (2018-06-21)
Lignans are polyphenolic compounds that are considered phytoestrogens for their plant origins, and they possess different biological activities. Three different extraction methods, ie, "dilute and shoot", acidic hydrolysis, and enzymatic digestion, have been compared for extracting lignans (secoisolariciresinol (SECO), matairesinol
P Majumder et al.
The FEBS journal, 274(15), 3886-3899 (2007-07-12)
To investigate the mechanism of increased expression of caspase-1 caused by exogenous Hippi, observed earlier in HeLa and Neuro2A cells, in this work we identified a specific motif AAAGACATG (- 101 to - 93) at the caspase-1 gene upstream sequence
Siti Khairunisah Ghazali et al.
Polymers, 13(4) (2021-02-10)
The elimination of mercury, low energy consumption, and low heat make the ultraviolet light-emitting diode (UV-LED) system emerge as a promising alternative to conventional UV-mercury radiation coating. Hence, a series of hydrophobic coatings based on urethane acrylate oligomer and fluorinated
Yong-Hong Liu et al.
Neurochemical research, 34(7), 1209-1218 (2009-01-06)
Epilepsy is a serious neurological disorder with neuronal loss and spontaneous recurrent seizures, but the neurochemical basis remains largely unclear. We hypothesize that D-serine, a newly identified endogenous co-agonist of N-methyl-D-aspartate (NMDA) receptor, may trigger excitotoxicity and neuronal damage in
L Jørgensen et al.
Molecular biology reports, 26(1-2), 119-123 (1999-06-11)
20 S Proteasomes are large proteinase complexes found in eukaryotic cells where they degrade cell proteins in an ATP-dependent manner. Proteasomes consist of 14 different subunits. One of them, zeta, was found in HeLa cells at a concentration of 890
S Tate et al.
Biochemistry, 34(45), 14637-14648 (1995-11-14)
The solution structure of a human cystatin A variant, cystatin A2-98 M65L, which maintains the full inhibitory activity of the wild-type protein, was determined at pH 3.8 by sD/3D heteronuclear double- and triple-resonance NMR spectroscopy. The structure is based on
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