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显示 31-60 共 329 条结果 关于 "94-12-2" 范围 论文
Okko T Pyykkö et al.
Journal of neurology, neurosurgery, and psychiatry, 83(11), 1119-1124 (2012-09-08)
To investigate the association of apolipoprotein E (APOE) genotype, especially the APOE4 allele, to (1) idiopathic normal pressure hydrocephalus (iNPH) and (2) amyloid-β (Aβ) plaques in cortical brain biopsies of presumed NPH patients with and without a final clinical diagnosis
Geon Park et al.
Annals of hematology, 90(1), 73-79 (2010-08-20)
Disruption of cell cycle control genes, including p16, is known to contribute to the cancerogenesis of multiple myeloma (MM). We investigated the methylation status of p16 and its association with common cytogenetic changes, clinicolaboratory findings, and survival in MM. Methylation-specific
Xiao-fei Jiang et al.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 41(6), 951-954 (2011-01-27)
To study the influence and mechanism of hypoxia on the expression of angiotensin-converting enzyme 2 (ACE2) in human umbilical vein endothelial cells (HUVECs). HUVECs were cultured as adherent cells and identified by immunohistochemical study of Factor VIII. Then the cells
Won Joong Kim et al.
The Journal of international medical research, 41(4), 1203-1213 (2013-06-15)
To compare the efficacy of ramosetron, midazolam, and the combination of ramosetron and midazolam in the prevention of postoperative nausea and vomiting (PONV) in female patients undergoing thyroidectomy. Patients were randomized to receive 0.3 mg ramosetron (Group R), 75 µg/kg
Nezam Afdhal et al.
The New England journal of medicine, 370(20), 1889-1898 (2014-04-15)
In phase 2 studies, treatment with the all-oral combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor ledipasvir resulted in high rates of sustained virologic response among previously untreated patients with hepatitis C virus (HCV) genotype 1 infection.
Christopher J Yates et al.
Transplantation, 96(8), 726-731 (2013-08-02)
The sensitivity of fasting plasma glucose (FPG) in screening for new-onset diabetes after transplantation (NODAT) has been questioned, particularly in the presence of moderate-dose prednisolone, where peak plasma glucose occurs 7 to 8 hr after administration. Oral glucose tolerance testing
M C Yagmurdur et al.
International surgery, 93(3), 163-168 (2008-10-03)
The study group was derived from the archive materials of 55 invasive ductal breast cancer (IDC) patients who had undergone breast-preserving surgery (partial mastectomy/ axillary dissection). All patients included in the study had clinically T(1)-2, N0-M0 invasive ductal carcinoma. Genomic
Xin Hong et al.
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 21(4), 423-426 (2005-11-01)
To investigate the relationship between the hypoxia-inducible factor 1(HIF-1) and apoptosis correlative proteins in the cardiomyocyte during hypoxia. Rat cardiomyocytes cultured in vitro were divided into normoxia, hypoxia and hypoxic preconditioning groups. The cardiomyocytes in hypoxic preconditioning group were cultured
Sarah Edkins et al.
Cancer biology & therapy, 5(8), 928-932 (2006-09-14)
An activating point mutation in codon 12 of the HRAS gene was the first somatic point mutation identified in a human cancer and established the role of somatic mutations as the common driver of oncogenesis. Since then, there have been
F M van der Zant et al.
Clinical and experimental rheumatology, 27(1), 130-139 (2009-03-31)
To perform a systemic review and meta-analysis on the effectiveness of radiosynoviorthesis (RSO). A search of medical databases was conducted. Criteria for inclusion: articles in English, minimum follow-up of 6 months, specification of joint disease, reported outcome of at least
Alena Skálová et al.
The American journal of surgical pathology, 45(1), 1-13 (2020-10-08)
Myoepithelial carcinoma of salivary glands is an underrecognized and challenging entity with a broad morphologic spectrum, including an EWSR1-rearranged clear cell variant. Myoepithelial carcinoma is generally aggressive with largely unknown genetic features. A retrospective review of Salivary Gland Tumor Registry
Styliana I Mirallai et al.
The Journal of organic chemistry, 78(17), 8655-8668 (2013-07-31)
Eight 2-phenyl-3H-imidazo[4,5-b]quinoline-9-carbonitriles 15 are prepared in four steps from N'-arylbenzamidines 11 and tetracyanoethylene (TCNE) in ~70-90% yields. The transformation involves the initial formation of N-aryl-N'-(1,2,2-tricyanovinyl)benzamidines 12 in 87-99% yields, which in MeCN undergo a 5-exodig cyclization to give the 2-[1-aryl-5-imino-2-phenyl-1H-imidazol-4(5H)-ylidene]malononitriles
Yu Liu et al.
The Canadian journal of cardiology, 30(3), 368-375 (2014-02-26)
Endoplasmic reticulum (ER) stress plays an important role in mediating ischemic heart cell death. The aim of this study was to investigate whether manipulation of a key factor of the ER stress pathway, eukaryotic translation initiation factor 2 subunit α
Peter S Lacy et al.
Journal of the renin-angiotensin-aldosterone system : JRAAS, 16(3), 614-622 (2015-05-07)
Whilst sustained lowering of brachial systolic blood pressure (Br-SBP) and central aortic systolic pressure (CASP) have been demonstrated in patients with hypertension, effects of treatment withdrawal on these parameters have not been investigated. The ASSERTIVE study previously reported more sustained
Job Harenberg et al.
European journal of clinical investigation, 44(8), 743-752 (2014-06-17)
The determination of rivaroxaban and apixaban from serum samples of patients may be beneficial in specific clinical situations when additional blood sampling for plasma and thus the determination of factor Xa activity is not feasible or results are not plausible.
Anton J L M van Balkom et al.
Psychotherapy and psychosomatics, 81(6), 366-374 (2012-09-12)
To compare the effectiveness of second-step treatment with cognitive therapy (CT) versus fluvoxamine in patients with obsessive-compulsive disorder (OCD) who are nonresponsive to exposure in vivo with response prevention (ERP). A 12-week randomized controlled trial at an outpatient clinic in
Ian F Burgess et al.
BMJ (Clinical research ed.), 330(7505), 1423-1423 (2005-06-14)
To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. Randomised controlled equivalence trial. Community, with home visits. 214 young people aged 4 to 18 years and 39 adults with active head louse infestation.
Scott A MacDiarmid et al.
Urology, 77(1), 24-29 (2010-10-26)
This study used pooled data from 2 large, phase III, double-blind, randomized, placebo-controlled studies for a subgroup analysis of the safety and efficacy of trospium chloride extended-release (XR) in men with overactive bladder (OAB). A subgroup analysis was performed on
Lionel Kerhuel et al.
Minerva anestesiologica, 82(11), 1180-1188 (2016-09-15)
In several countries, a computed tomography angiography (CTA) is used to confirm brain death (BD). A six‑hour interval is recommended between clinical diagnosis and CTA acquisition despite the lack of strong evidence to support this interval. The aim of this
D E Humphries et al.
The Biochemical journal, 332 ( Pt 2), 303-307 (1998-06-26)
The cDNA and gene encoding human heparan glucosaminyl N-deacetylase/N-sulphotransferase-2 have been cloned. The cDNA encoded a protein of 883 amino acids that was 94% similar to heparan N-sulphotransferase-2 from mouse mast cells. Comparison of the deduced amino acid sequences of
David L Wyles et al.
Hepatology (Baltimore, Md.), 60(1), 56-64 (2014-02-07)
This phase II trial assessed the efficacy and safety of a combination regimen of the nonstructural protein (NS)5A inhibitor ledipasvir (LDV), NS3 protease inhibitor vedroprevir (VDV), non-nucleoside NS5B inhibitor tegobuvir (TGV), and ribavirin (RBV) in treatment-naïve patients with chronic hepatitis
Mustapha Oubenali et al.
ChemSusChem, 4(7), 950-956 (2011-06-10)
Carbon nanotubes (CNTs) and carbon nanofibers (CNFs) have been used for the first time to support ruthenium nanoparticles for the hydrogenation of p-chloronitrobenzene (p-CNB) to produce selectively p-chloroaniline. The preparation of well-dispersed ruthenium catalysts from the [Ru(3)(CO)(12)] precursor required activation
Fuminao Sekiguchi et al.
Asia-Pacific journal of public health, 24(2), 288-295 (2011-12-14)
The objective of this study was to replicate the associations between the serotonin transporter genotypes and smoking cessation and between these genotypes and long-term smoking cessation success (for 2 years or more). Two case-control designs were used in this study.
Erik E Folch et al.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 14(3), 445-458 (2018-11-27)
Electromagnetic navigation bronchoscopy (ENB) is a minimally invasive technology that guides endoscopic tools to pulmonary lesions. ENB has been evaluated primarily in small, single-center studies; thus, the diagnostic yield in a generalizable setting is unknown. NAVIGATE is a prospective, multicenter, cohort
Yun Xu et al.
Zhonghua zhong liu za zhi [Chinese journal of oncology], 34(3), 205-209 (2012-07-12)
To detect the expression of phosphorylated girdin (p-girdin) in breast cancer and its association with pathological characteristics and molecular subtypes of breast cancer. Immunohistochemical SP staining was used to investigate the expression of p-girdin in 27 cases of lobular hyperplasia
Seong-Beom Lee et al.
Immunogenetics, 55(3), 177-181 (2003-05-14)
Interleukin-12 receptor beta 1 ( IL12RB1), interleukin-12 receptor beta 2 ( IL12RB2), and interferon gamma receptor 1 ( IFNGR1) perform important roles in the host defense against intracellular pathogens such as Mycobacteria. Several mutations within their genes have been confirmed
Chong-xiao Liu et al.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 30(3), 435-438 (2010-03-26)
To study the effect of glutamate on the expression of vascular endothelial growth factor (VEGF) mRNA and protein in cultured rat astrocytes under hypoxia. Cultured rat astrocytes were randomly divided control group, glutamate group, hypoxia group and hypoxia+glutamate group. The
Shareen Forbes et al.
Diabetologia, 58(6), 1300-1308 (2015-03-27)
Type 1 diabetes complicated by hypoglycaemia is prevalent in socioeconomically deprived populations. Islet transplantation is of proven efficacy in type 1 diabetes complicated by hypoglycaemia, but it is not known if nationally funded programmes reach the socioeconomically deprived. Our aim
P A Crossey et al.
Human molecular genetics, 3(8), 1303-1308 (1994-08-01)
Von Hippel-Lindau (VHL) disease is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign neoplasms, most frequently retinal, cerebellar and spinal haemangioblastoma, renal cell carcinoma, phaeochromocytoma and pancreatic tumours. We have previously detected large germline
Gao-Song Wu et al.
Hepatobiliary & pancreatic diseases international : HBPD INT, 1(3), 429-433 (2003-11-11)
To investigate the expression of cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) in extra-hepatic cholangiocarcinoma and the relationship between their expression and clinicopathological parameters. COX-1 and COX-2 were detected in 56 extra-hepatic cholangiocarcinomas, including 31 matched tissues originating from non-tumorous bile ductal
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