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Behrad Elmiyeh et al.
Logopedics, phoniatrics, vocology, 35(1), 39-44 (2010-03-31)
We reviewed the results and side-effect profile of the Dysport preparation of botulinum toxin A (BTA) in the management of the adductor spasmodic dysphonia. We performed 272 injection episodes in 68 patients, 42 (62%) female, 26 (38%) male. A total
N Hamajima et al.
Gene, 180(1-2), 157-163 (1996-11-21)
We have isolated cDNA clones encoding dihydropyrimidinase (DHPase) from human liver and its three homologues from human fetal brain. The deduced amino acid (aa) sequence of human DHPase showed 90% identity with that of rat DHPase, and the three homologues
Camilo G Borrero et al.
Skeletal radiology, 47(2), 203-214 (2017-10-07)
To determine the effect of patient age on the accuracy of primary MRI signs of long head of biceps (LHB) tendon tearing and instability in the shoulder using arthroscopy as a reference standard. Subjects with MRI studies and subsequent arthroscopy
V Sama et al.
Arzneimittel-Forschung, 62(8), 384-388 (2012-07-04)
Piperine (CAS no: 94-62-2), an alkaloid obtained from Piper nigrum and P. longum is a known inhibitor of various enzymes (CYP isozymes) responsible for biotransformation of drugs. By inhibiting the metabolism of drugs, piperine improves the bioavailability of drugs. In
Guillermo J Ruiz-Delgado et al.
Hematology (Amsterdam, Netherlands), 17(3), 140-143 (2012-06-06)
Twenty-nine consecutive patients with hairy cell leukemia (HCL) were treated in two institutions with interferon (IFN, n = 18) or cladribine (n = 11), between July 1987 and May 2011. Median age was 62 (range 29-83) years; there were 21
Szlavik et al.
Organic letters, 2(15), 2347-2349 (2000-08-10)
A convenient and effective method for the preparation of perfluoroalkylated ethenes is described. First, the free radical addition of perfluoroalkyl iodides to trimethylvinylsilane in the presence of AIBN gave iodoethylsilane intermediates (F(CF(2))(n)()CH(2)CHISiMe(3), n = 4 (1), 6 (2), 8 (3)
Javier P Gisbert et al.
Digestive diseases and sciences, 60(2), 458-464 (2014-09-23)
Helicobacter pylori eradication is a challenge in penicillin allergy. To assess the efficacy and safety of first-line and rescue treatments in patients allergic to penicillin. Prospective multicenter study. Patients allergic to penicillin were given a first-line treatment comprising (a) 7-day
T Vermeire et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(7), 907-907 (2018-12-07)
Mumps used to affect children between 2 and 15 years old. The mumps-measles-rubella (MMR) vaccine is available, with vaccine coverage rate of about 85% after two vaccine doses. Recently new mumps outbreaks have emerged in highly vaccinated populations; the causes for
Jair Segal et al.
Neuroscience letters, 451(1), 79-82 (2008-12-24)
A polymorphism in the serotonin transporter gene (5-HTTLPR) is being extensively studied for association with suicidal behavior. A new allelic variant within the 5-HTTLPR polymorphism was described but it has not been thoroughly analyzed in the recent literature. The SNP
Yun Xu et al.
Zhonghua zhong liu za zhi [Chinese journal of oncology], 34(3), 205-209 (2012-07-12)
To detect the expression of phosphorylated girdin (p-girdin) in breast cancer and its association with pathological characteristics and molecular subtypes of breast cancer. Immunohistochemical SP staining was used to investigate the expression of p-girdin in 27 cases of lobular hyperplasia
Carol L Shields et al.
Ophthalmology, 121(7), 1453-1460 (2014-03-25)
To analyze our 5-year experience of intra-arterial chemotherapy (IAC) for retinoblastoma as primary or secondary therapy. Retrospective interventional case series. A total of 70 eyes of 67 patients. Ophthalmic artery chemotherapy infusion under fluoroscopic guidance was performed using melphalan (3
Tetsunari Takai et al.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 18(6), 1888-1893 (2009-06-10)
We previously reported that fecal cyclooxygenase 2 (COX-2) mRNA assay, detecting COX-2 mRNA in feces, is useful for identifying subjects with colorectal cancer (CRC). To further improve the sensitivity, we evaluated the usefulness of the combination of COX-2 mRNA and
Jun Yu et al.
Hepatology (Baltimore, Md.), 51(6), 2008-2019 (2010-06-01)
Although peroxisome proliferator-activated receptor gamma (PPARgamma) agonist have been shown to inhibit hepatocellular carcinoma (HCC) development, the role of PPARgamma in hepatocarcinogenesis remains unclear. We investigated the therapeutic efficacy of PPARgamma against HCC. PPARgamma-deficient (PPARgamma(+/-)) and wild-type (PPARgamma(+/+)) littermates were
Sandi A Kwee et al.
Annals of nuclear medicine, 26(6), 501-507 (2012-05-03)
To evaluate fluorine-18 fluorocholine (FCH) PET/CT for the detection of recurrent prostate cancer in relation to prostate-specific antigen (PSA) level. FCH PET/CT was performed in 50 patients with rising PSA levels at follow-up of primary treatment of prostate cancer (radical
Robin P Lazarus et al.
The American journal of tropical medicine and hygiene, 93(5), 931-938 (2015-08-26)
Little is known about the type and longevity of the humoral response to cryptosporidial infections in developing countries. We evaluated serum antibody response to Cryptosporidium gp15 in 150 sets of maternal, preweaning and postinfection/end-of-follow-up sera from children followed up to
Anthony Sclafani et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 315(3), R434-R441 (2018-04-19)
Fatty acid receptors in the mouth and gut are implicated in the appetite for fat-rich foods. The role of lipolysis in oral- and postoral-based fat preferences of C57BL/6J mice was investigated by inhibiting lipase enzymes with orlistat. Experiment 1 showed
Kristin Pétursdóttir et al.
Laeknabladid, 99(2), 77-81 (2013-03-15)
Intussusception occurs when a proximal portion of the bowel invaginates into the distal bowel. It is the most common cause of intestinal obstruction in children between 3 months and 3 years. This study aimed to assess patient profile, clinical presentation
Xiangfen Yuan et al.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 31(3), 415-425 (2019-04-06)
Advances in molecular testing and microfluidic technologies have opened new avenues for rapid detection of animal viruses. We used a centrifugal microfluidic disk (CMFD) to detect 6 important swine viruses, including foot-and-mouth disease virus, classical swine fever virus, porcine reproductive
Caio Max Rocha-Lima et al.
Cancer chemotherapy and pharmacology, 74(3), 479-486 (2014-07-18)
The G17DT is a novel human immunogen that raises antibodies to the growth factor gastrin 17 (G17). The purpose of this study was to determine the safety and efficacy of G17DT in combination with irinotecan in patients refractory to irinotecan
K Pettersson-Fernholm et al.
Kidney international, 69(10), 1880-1884 (2006-04-07)
Diabetic nephropathy shows a higher incidence in male subjects, which may in part be owing to genetic factors. The angiotensin II type 2 receptor (AT2), present in the renal glomerulus, may oppose the deleterious effects of the type I receptor
Patrick A Adegboyega et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 10(17), 5870-5879 (2004-09-10)
Recent data support the hypothesis that the inducible isoform of cyclooxygenase (COX-2) plays a role in the early stages of colonic carcinogenesis and that nonsteroidal anti-inflammatory drugs (NSAIDs) retard the development of colon cancer by modulating COX-2. However, the cell
Nic Waddell et al.
PLoS genetics, 4(5), e1000080-e1000080 (2008-05-24)
The functional consequences of missense variants in disease genes are difficult to predict. We assessed if gene expression profiles could distinguish between BRCA1 or BRCA2 pathogenic truncating and missense mutation carriers and familial breast cancer cases whose disease was not
Nurhan Güler et al.
TheScientificWorldJournal, 2012, 946060-946060 (2012-07-11)
The aim of this study was to investigate whether there is any association between inflammation and the expression of markers of cell cycle entry (Ki-67 and MCM-2) in dental follicle (DF) of asymptomatic impacted teeth and odontogenic cysts. The study
Jianhui Shi et al.
Human pathology, 38(9), 1335-1344 (2007-05-22)
p16INK4a has been shown to be overexpressed in nearly all high-grade squamous intraepithelial lesions (HSILs). Other cell-cycle regulators, such as minichromosome maintenance protein 2 (MCM2), DNA topoisomerase IIalpha (TOP IIA), and ProE(X) C (a cocktail of MCM2 and TOP IIA)
S C Khojasteh-Bakht et al.
Drug metabolism and disposition: the biological fate of chemicals, 27(5), 574-580 (1999-04-30)
(R)-(+)-Pulegone, a monoterpene constituent of pennyroyal oil, is a hepatotoxin that has been used in folklore medicine as an abortifacient despite its potential lethal effects. Pulegone is metabolized by human liver cytochrome P-450s to menthofuran, a proximate hepatotoxic metabolite of
Martin U Braun et al.
Molecular and cellular biochemistry, 262(1-2), 135-143 (2004-11-10)
Protein kinase C (PKC) is a family of at least 11 isozymes and known to play a crucial role in myocardial growth. The present study was performed to investigate whether PKC-isozymes are differentially regulated during the development of volume-overload cardiac
Z Tiszlavicz et al.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 10(4), 483-490 (2010-08-20)
Bacterial translocation from the intestinal tract plays an important role in severe acute pancreatitis (AP). Human β-defensins are a family of antimicrobial peptides present at the mucosal surface. The aim of this study was to investigate the relevance of single
G Geldner et al.
Anaesthesia, 67(9), 991-998 (2012-06-16)
Deep neuromuscular blockade during certain surgical procedures may improve operating conditions. Sugammadex can be used to reverse deep neuromuscular blockade without waiting for spontaneous recovery. This randomised study compared recovery times from neuromuscular blockade induced by rocuronium 0.6 mg.kg(-1), using
Shanthi Priya Samudrala et al.
Scientific reports, 8(1), 7484-7484 (2018-05-12)
Direct C-O hydrogenolysis of bioglycerine to produce 1,3-propanediol selectively is a vital technology that can expand the scope of biodiesel industry and green chemical production from biomass. Herein we report sulphuric acid-activated montmorillonite clay supported platinum nanoparticles as highly effective
Vahid Asnafi et al.
Blood, 113(17), 3918-3924 (2008-12-26)
Many somatic genetic abnormalities have been identified in T-cell acute lymphoblastic leukemia (T-ALL) but each individual abnormality accounts for a small proportion of cases; therapeutic stratification consequently still relies on classical clinical markers. NOTCH1 and/or FBXW7 mutations both lead to
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