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显示 1-30 共 106 条结果 关于 "95-81-8" 范围 论文
Laurence M M Crombag et al.
The European respiratory journal, 53(2) (2018-12-24)
Guidelines recommend endosonography for mediastinal nodal staging in patients with resectable nonsmall cell lung cancer (NSCLC). We hypothesise that a systematic endobronchial ultrasound (EBUS) evaluation combined with an oesophageal investigation using the same EBUS bronchoscope (EUS-B) improves mediastinal nodal staging
S Trattnig et al.
Osteoarthritis and cartilage, 23(12), 2224-2232 (2015-07-19)
To evaluate cartilage repair tissue (RT) using MOCART scoring for morphological and T2 mapping for biochemical assessment following implantation of GelrinC, a biosynthetic, biodegradable hydrogel implant. MR imaging (1.5/3T) was performed on 21 patients at six sites. Standard protocols were
Shyam Sundar et al.
Tropical medicine & international health : TM & IH, 18(1), 96-100 (2012-11-10)
Standard treatment of Indian post-kala-azar dermal leishmaniasis (PKDL) is unsatisfactory because to achieve therapeutic effectiveness, heroic courses of parenteral and toxic agents have to be administered. Our objective was to evaluate oral miltefosine for its potential to provide effective as
Gregory J Riely et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 14(18), 5731-5734 (2008-09-17)
KRAS mutations are found in approximately 25% of lung adenocarcinomas in Western countries and, as a group, have been strongly associated with cigarette smoking. These mutations are predictive of poor prognosis in resected disease as well as resistance to treatment
Kazuhiro Asami et al.
Clinical lung cancer, 12(6), 387-392 (2011-07-07)
Efficacy of first-line gefitinib for elderly epidermal growth factor receptor mutated patients with lung adenocarcinoma is uncertain. This study was aimed to investigate efficacy of gefitinib for such population. The primary endpoint was response rate (RR) and at least 12
T Vermeire et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(7), 907-907 (2018-12-07)
Mumps used to affect children between 2 and 15 years old. The mumps-measles-rubella (MMR) vaccine is available, with vaccine coverage rate of about 85% after two vaccine doses. Recently new mumps outbreaks have emerged in highly vaccinated populations; the causes for
Chiaki Kawanishi et al.
European journal of clinical pharmacology, 59(11), 803-807 (2003-12-04)
Recent studies have revealed that genetic polymorphisms of cytochrome P(450) 2D6 (CYP2D6) are among the factors that determine the interindividual differences in the metabolism and response to antidepressants. We investigated the relationship between persistent mood disorders and the duplication of
J Cebon et al.
British journal of cancer, 95(7), 853-861 (2006-09-06)
Octreotide may extend survival in hepatocellular carcinoma (HCC). Forty-one per cent of HCCs have high-affinity somatostatin receptors. We aimed to determine the feasibility, safety, and activity of long-acting octreotide in advanced HCC; to identify the best method for assessing somatostatin
Amit N Vora et al.
Journal of thrombosis and thrombolysis, 34(2), 229-234 (2012-03-27)
Elevated levels of myeloid-related protein (MRP)-8/14 (S100A8/A9) are associated with first cardiovascular events in healthy individuals and worse prognosis in patients with acute coronary syndrome (ACS). The diagnostic utility of MRP-8/14 in patients presenting to the emergency room with symptoms
Delphine Détaint et al.
European heart journal, 31(18), 2223-2229 (2010-08-17)
In patients with Marfan syndrome and other type-1 fibrillinopathies, genetic testing is becoming more easily available, leading to the identification of mutations early in the course of the disease. This study evaluates the cardiovascular (CV) risk associated with the discovery
Fergus J Couch et al.
PLoS genetics, 9(3), e1003212-e1003212 (2013-04-02)
BRCA1-associated breast and ovarian cancer risks can be modified by common genetic variants. To identify further cancer risk-modifying loci, we performed a multi-stage GWAS of 11,705 BRCA1 carriers (of whom 5,920 were diagnosed with breast and 1,839 were diagnosed with
W Larsen et al.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society, 9(4), 202-206 (1998-11-11)
To determine the frequency of responses to four mixtures of fragrance materials in routine clinic patients undergoing patch testing for suspect allergic contact dermatitis. The validity of using fragrance mixtures alone, or in combination, was evaluated in terms of predicting
S Stadlmann et al.
European journal of cancer (Oxford, England : 1990), 39(17), 2499-2505 (2003-11-07)
Matrix metalloproteinases (MMPs) have been implicated in ovarian cancer progression. Among them, MMP-8 that degrades type I collagen may play a crucial role. The aim of our study was to determine MMP-8 expression and regulation in ovarian cancer and its
Yutaka Kimura et al.
Toxicology in vitro : an international journal published in association with BIBRA, 29(7), 1816-1830 (2015-07-19)
We previously reported a dataset of the IL-8 Luc assay covering reference chemicals published by ECVAM, in which the effects of chemicals on IL-8 promoter activity were evaluated by an IL-8 reporter cell line, THP-G8 cells. To clarify its performance
Marc Lilot et al.
Anesthesia and analgesia, 117(1), 259-264 (2013-04-18)
In this randomized, prospective trial, we sought to determine the effective dose of hypobaric ropivacaine with sufentanil providing 95% success (ED95) in spinal anesthesia for traumatic femoral neck surgery in the elderly. Sixty-eight elderly patients with unilateral hip fracture randomly
Paulino Vigil-De Gracia et al.
American journal of obstetrics and gynecology, 209(5), 425-425 (2013-08-21)
The objective of the study was to determine whether expectant management of severe preeclampsia prior to 34 weeks of gestation results in improved neonatal outcome in countries with limited resources. This was a randomized clinical trial performed in 8 tertiary
Christopher J D McKinlay et al.
Pediatrics, 135(2), e405-e415 (2015-01-21)
Treatment of women at risk for preterm birth with repeat doses of glucocorticoids reduces neonatal morbidity but could have adverse long-term effects on cardiometabolic health in offspring. We assessed whether exposure to repeat antenatal betamethasone increased risk factors for later
Biodegradation of kerosene: Study of growth optimization and metabolic fate of P. janthinellum SDX7.
Shamiyan R Khan et al.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 46(2), 397-406 (2015-08-15)
Penicillum janthinellum SDX7 was isolated from aged petroleum hydrocarbon-affected soil at the site of Anand, Gujarat, India, and was tested for different pH, temperature, agitation and concentrations for optimal growth of the isolate that was capable of degrading upto 95%
Yi Li et al.
Zhonghua nei ke za zhi, 47(3), 213-216 (2008-09-13)
To investigate the association between the exon 2, 3, 4 of MHC class I chain-related gene-B (MICB) and ulcerative colitis (UC) in Chinese Han. Using polymerase chain reaction single-stranded conformation polymorphism, allele frequency of MICB exon 2, 3 and 4
Meera Mohan et al.
British journal of haematology, 189(1), 67-71 (2019-12-11)
Gain of chromosome 1q21 and the gene expression-based GEP70 risk score are established prognostic markers for newly diagnosed Multiple Myeloma (MM) patients. Here we addressed the prognostic impact of these two markers in 81 relapsed/refractory (RR) MM patients treated with
Jacqueline A French et al.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 9(1), 176-184 (2011-12-06)
The efficacy and safety of lamotrigine extended-release tablets (LTG XR) as monotherapy for partial seizures were evaluated using the conversion-to-monotherapy design, and historical data as the control. This methodology was recently approved by the United States Food and Drug Administration
F Sanfilippo et al.
British journal of anaesthesia, 112(2), 298-303 (2013-09-27)
This study was to evaluate the usefulness of hepato-biliary ultrasound (HBUS) for the investigation of isolated liver function tests (LFTs) abnormalities. We retrospectively reviewed HBUS reports in traumatic brain injury (TBI) patients admitted to our tertiary neuro-critical care unit (NCCU;
Sonu Bhaskar et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 37(3), 1148-1162 (2016-06-04)
Focal hyperperfusion after acute ischaemic stroke could be of prognostic value depending upon its spatial localisation and temporal dynamics. Factors associated with late stage (12-24 h) perilesional hyperperfusion, identified using arterial spin labelling, are poorly defined. A prospective cohort of acute
Gema Fernandez Juarez et al.
American journal of kidney diseases : the official journal of the National Kidney Foundation, 61(2), 211-218 (2012-09-04)
Blockade of the renin-angiotensin system with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers has been shown to lessen the rate of decrease in glomerular filtration rate in patients with diabetic nephropathy. A multicenter open-label randomized controlled trial to compare
José M A Wijnands et al.
Rheumatology (Oxford, England), 53(11), 2053-2062 (2014-06-12)
The aims of this study were to investigate (i) associations between uric acid and prevalent cardiovascular disease (CVD), ankle-arm blood pressure index (AAIx) and carotid intima-media thickness (CIMT) in the total population and in predefined subgroups according to glucose metabolism
Asger Granfeldt et al.
Critical care (London, England), 18(6), 682-682 (2014-12-17)
The combination of Adenosine (A), lidocaine (L) and Mg(2+) (M) (ALM) has demonstrated cardioprotective and resuscitative properties in models of cardiac arrest and hemorrhagic shock. This study evaluates whether ALM also demonstrates organ protective properties in an endotoxemic porcine model.
Xiao S Liu et al.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes, 44(6), 591-597 (2010-02-26)
A method using liquid chromatography and a single mix-mode solid-phase extraction cleanup for the simultaneous analysis of thiabendazole [2-(1,3-thiazol-4-yl)-1H-benzoimidazole], carbendazim [(methyl N-(1H-benzoimidazol-2-yl)-carbamate)] and 2-aminobenzimidazole (1H-benzimidazol-2-amine) in concentrated fruit juices is described. The three fungicides were isolated from the samples and
Nicola Veronese et al.
Journal of the American Medical Directors Association, 19(11), 981-988 (2018-07-30)
Slow gait speed may be associated with premature mortality, cardiovascular disease (CVD), and cancer, although a comprehensive meta-analysis is lacking. In this systematic review and meta-analysis, we explored potential associations between gait speed and mortality, incident CVD, and cancer. A
Ian F Burgess et al.
PloS one, 7(4), e35419-e35419 (2012-04-24)
Interest in developing physically active pediculicides has identified new active substances. The objective was to evaluate a new treatment for clinical efficacy. We describe the selection of 1,2-octanediol as a potential pediculicide. Clinical studies were community based. The main outcome
Lionel D Lewis et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 13(11), 3302-3311 (2007-06-05)
Increased clearance of drugs, such as oral cyclosporine, that are CYP3A and/or ABCB1 (P-gp/MDR1) substrates was reported in African-American compared with Caucasian patients. We hypothesized that the pharmacokinetics and pharmacodynamics of docetaxel, an i.v. administered cytotoxic and substrate for CYP3A4
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