95-92-1

应用筛选条件

关键词:'95-92-1'

显示 1-30 共 350 条结果关于 "95-92-1" 范围论文

Identification of eight-protein biosignature for diagnosis of tuberculosis.

Qianting Yang et al.

Thorax, 75(7), 576-583 (2020-03-24)

Biomarker-based tests for diagnosing TB currently rely on detecting Mycobacterium tuberculosis (Mtb) antigen-specific cellular responses. While this approach can detect Mtb infection, it is not efficient in diagnosing TB, especially for patients who lack aetiological evidence of the disease. We

Uterine artery pulsatility index improves prediction of methotrexate resistance in women with gestational trophoblastic neoplasia with FIGO score 5-6.

A Sita-Lumsden et al.

BJOG : an international journal of obstetrics and gynaecology, 120(8), 1012-1015 (2013-06-14)

The Uterine Artery Pulsatility Index (UAPI) is an ultrasound measure of tumour vascularity. In this study, we hypothesised that a UAPI ≤ 1 (high vascularity) would identify women with gestational trophoblastic neoplasia (GTN) at increased risk of resistance to first-line

PADI4 polymorphisms and related haplotype in rheumatoid arthritis patients.

Somia H Abd-Allah et al.

Joint, bone, spine : revue du rhumatisme, 79(2), 124-128 (2011-10-11)

To investigate whether peptidyl arginine deiminase type IV gene (PADI4) polymorphisms contribute to rheumatoid arthritis (RA) susceptibility in Egyptians, whether they influence disease severity and activity, and whether they affect anti-mutated citrullinated vimentin antibodies (anti-MCV) level. Three PADI4 single nucleotide

Effect of hydroxyapatite coating on the radio-clinical results of a grit-blasted titanium alloy femoral taper. A case-control study of 198 cementless primary total hip arthroplasty with the Alloclassic™ system.

C Delaunay

Orthopaedics & traumatology, surgery & research : OTSR, 100(7), 739-744 (2014-09-28)

The effect of hydroxyapatite (HA) coating on the fixation of a cementless femoral stem is discussed, in particular in cases of primary fixation with geometrically stable components. Therefore, we performed a comparative retrospective study of a series of Alloclassic-SL™ stems

Organocatalysis with a fluorous tag: asymmetric reduction of imines with trichlorosilane catalyzed by amino acid-derived formamides.

Andrei V Malkov et al.

The Journal of organic chemistry, 72(4), 1315-1325 (2007-02-10)

Asymmetric reduction of ketimines 1 with trichlorosilane can be catalyzed by N-methylvaline-derived Lewis-basic formamides 3a-d with high enantioselectivity (< or =95% ee) and low catalyst loading (1-5 mol %) at room temperature in toluene. Appending a fluorous tag, as in

Crystal structure and mutational analysis of heparan sulfate 3-O-sulfotransferase isoform 1.

Suzanne C Edavettal et al.

The Journal of biological chemistry, 279(24), 25789-25797 (2004-04-03)

Heparan sulfate interacts with antithrombin, a protease inhibitor, to regulate blood coagulation. Heparan sulfate 3-O-sulfotransferase isoform 1 performs the crucial last step modification in the biosynthesis of anticoagulant heparan sulfate. This enzyme transfers the sulfuryl group (SO(3)) from 3'-phosphoadenosine 5'-phosphosulfate

Enhanced therapy for primary and secondary syphilis: a longitudinal retrospective analysis of cure rates and associated factors.

Julia Tittes et al.

International journal of STD & AIDS, 24(9), 703-711 (2013-09-13)

For the treatment of early infectious syphilis, enhanced therapy with three dosages of benzathine penicillin G has been under consideration, particularly in the human immunodeficiency virus type 1 infected population (HIV-1). The serological outcome of 249 patients with primary and

Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer.

Sunghoon Kim et al.

Journal of translational medicine, 12, 229-229 (2014-08-22)

To identify the novel epitopes from the human papillomavirus type 18 E7 which can sensitize PBMCs of four different major HLA class I A allele. Twenty-four synthetic overlapping 15-amino acid peptides were screened by measuring the frequency of CD8+ cytotoxic

Supercritical fluid extraction of chemical warfare agent simulants from soil.

W H Griest et al.

Journal of chromatography, 600(2), 273-277 (1992-05-29)

Chemical warfare agent simulants are efficiently recovered from 2-ppm spikes in 1 g of Rocky Mountain Arsenal Standard Soil using methanol-carbon dioxide (5:95) at 300 atm for 2 min at 60 degrees C. Recoveries (n = 3) were 79 +/-

High resolution melting curve analysis targeting the HBB gene mutational hot-spot offers a reliable screening approach for all common as well as most of the rare beta-globin gene mutations in Bangladesh.

Md Tarikul Islam et al.

BMC genetics, 19(1), 1-1 (2018-01-04)

Bangladesh lies in the global thalassemia belt, which has a defined mutational hot-spot in the beta-globin gene. The high carrier frequencies of beta-thalassemia trait and hemoglobin E-trait in Bangladesh necessitate a reliable DNA-based carrier screening approach that could supplement the

The 4G5G polymorphism in the gene for PAI-1 and the circadian oscillation of plasma PAI-1.

Johanna G van der Bom et al.

Blood, 101(5), 1841-1844 (2002-10-31)

Plasminogen activator inhibitor type I (PAI-1) antigen concentrations follow a circadian oscillation peaking in the morning. Some individuals show no apparent circadian rhythm, while others show up to a 10-fold variation in PAI-1 over 24 hours. Results from experimental studies

Randomised controlled trial of lipiodol transarterial chemoembolisation with or without amiodarone for unresectable hepatocellular carcinoma.

Mathieu Boulin et al.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 43(11), 905-911 (2011-08-02)

There is no consensus about the most effective method for transarterial chemoembolisation of hepatocellular carcinoma. The aim of this phase II trial was to compare the efficacy and toxicity of lipiodol transarterial chemoembolisation with amiodarone in association with pirarubicin or

Network-based approach identified cell cycle genes as predictor of overall survival in lung adenocarcinoma patients.

Yafei Li et al.

Lung cancer (Amsterdam, Netherlands), 80(1), 91-98 (2013-01-30)

Lung adenocarcinoma is the most common type of primary lung cancer. The purpose of this study was to delineate gene expression patterns for survival prediction in lung adenocarcinoma. Gene expression profiles of 82 (discovery set) and 442 (validation set 1)

Effect of adjuvant capecitabine or fluorouracil, with or without oxaliplatin, on survival outcomes in stage III colon cancer and the effect of oxaliplatin on post-relapse survival: a pooled analysis of individual patient data from four randomised controlled trials.

Hans-Joachim Schmoll et al.

The Lancet. Oncology, 15(13), 1481-1492 (2014-12-03)

Oxaliplatin-based adjuvant therapy is the standard of care for stage III colon cancer. Adjuvant capecitabine with or without oxaliplatin versus leucovorin and fluorouracil with or without oxaliplatin has not been directly compared; therefore, we aimed to analyse the efficacy and

Interference with netrin-1 and tumor cell death in non-small cell lung cancer.

Céline Delloye-Bourgeois et al.

Journal of the National Cancer Institute, 101(4), 237-247 (2009-02-13)

Netrin-1 may promote colorectal and breast tumorigenesis, by inhibiting apoptosis induced by its dependence receptors, deleted in colorectal cancer (DCC) and uncoordinated-5-homolog (UNC5H). The status of netrin-1 and its receptors in non-small cell lung cancer (NSCLC) was unknown. The levels

Maize porridge enriched with a micronutrient powder containing low-dose iron as NaFeEDTA but not amaranth grain flour reduces anemia and iron deficiency in Kenyan preschool children.

Catherine W Macharia-Mutie et al.

The Journal of nutrition, 142(9), 1756-1763 (2012-07-20)

Few studies have evaluated the impact of fortification with iron-rich foods such as amaranth grain and multi-micronutrient powder (MNP) containing low doses of highly bioavailable iron to control iron deficiency anemia (IDA) in children. We assessed the efficacy of maize

Peginterferon plus Ribavirin for HIV-infected Patients with Treatment-Naïve Acute or Chronic HCV Infection in Taiwan: A Prospective Cohort Study.

Chen-Hua Liu et al.

Scientific reports, 5, 17410-17410 (2015-12-01)

Data are limited on the effectiveness and safety of peginterferon plus ribavirin in HIV-infected Asian patients with acute or chronic HCV infection. HIV-infected Taiwanese patients with acute HCV infection received peginterferon plus weight-based ribavirin for 24 weeks (n = 24), and those

KOC (K homology domain containing protein overexpressed in cancer) and S100A4-protein immunoreactivity improves the diagnostic sensitivity of biliary brushing cytology for diagnosing pancreaticobiliary malignancies.

Saverio Ligato et al.

Diagnostic cytopathology, 36(8), 561-567 (2008-07-12)

Biliary tract brush cytology is one of the favored methods of evaluating lesions of the pancreatobiliary tract. However, although its specificity has been reported to be high (91-100%), the sensitivity is lower (30-88%). In this study we applied KOC and

Ti-crossed-Claisen condensation between carboxylic esters and acid chlorides or acids: a highly selective and general method for the preparation of various beta-keto esters.

Tomonori Misaki et al.

Journal of the American Chemical Society, 127(9), 2854-2855 (2005-03-03)

Ti-crossed-Claisen condensation between a 1:1 mixture of carboxylic esters and acid chlorides promoted by TiCl4-Bu3N-N-methylimidazole proceeded successfully to give various beta-keto esters in good yields with excellent selectivities (19 examples, approximately 48-95% yield; cross/self-selectivity = approximately 96/4-99/1). The present method

The CYP2C19 genotype and the use of oral contraceptives influence the pharmacokinetics of carisoprodol in healthy human subjects.

Jørgen G Bramness et al.

European journal of clinical pharmacology, 61(7), 499-506 (2005-07-16)

The aim of the present study was to investigate if subjects with one normal and one non-functional CYP2C19 allele (intermediate metabolizers; IMs) metabolized carisoprodol differently than individuals with two normal CYP2C19 alleles (extensive metabolizers; EMs) We also wanted to investigate

Effect of acetazolamide and autoCPAP therapy on breathing disturbances among patients with obstructive sleep apnea syndrome who travel to altitude: a randomized controlled trial.

Tsogyal D Latshang et al.

JAMA, 308(22), 2390-2398 (2012-12-13)

Many patients with obstructive sleep apnea syndrome (OSA) living near sea level travel to altitude, but this may expose them to hypoxemia and exacerbation of sleep apnea. The treatment in this setting is not established. To evaluate whether acetazolamide and

Excellent outcome of direct antiviral treatment for chronic hepatitis C in Switzerland.

Jacqueline Bachofner et al.

Swiss medical weekly, 148, w14560-w14560 (2018-01-30)

The introduction of direct acting antivirals (DAAs) for the therapy of chronic hepatitis C (CHC) has revolutionised treatment and marks a paradigm shift in the approach to this disease, rendering interferon-based therapies obsolete. We retrospectively and prospectively evaluated treatment results

Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.

Ajay Vora et al.

The Lancet. Oncology, 15(8), 809-818 (2014-06-14)

No randomised study has shown whether stratification of treatment by minimal residual disease (MRD) response improves outcome in children and young people with acute lymphoblastic leukaemia (ALL). We assessed whether children and young people with clinical standard and intermediate-risk ALL

The factor V Leiden mutation, high factor VIII, and high plasminogen activator inhibitor activity: etiologies for sporadic miscarriage.

Charles J Glueck et al.

Metabolism: clinical and experimental, 54(10), 1345-1349 (2005-09-13)

We hypothesized that the thrombophilic G1691A factor V Leiden gene mutation was a common significant cause of sporadic first trimester miscarriage. We compared thrombophilia and hypofibrinolysis in 92 women (85 white, 5 black, 2 other) with 1 or more pregnancies

Incidence and clinical features of extramedullary multiple myeloma in patients who underwent stem cell transplantation.

Mathew Weinstock et al.

British journal of haematology, 169(6), 851-858 (2015-04-03)

Extramedullary disease (EMD), defined as an infiltrate of clonal plasma cells at an anatomic site distant from the bone marrow, is an uncommon manifestation of multiple myeloma. Six hundred and sixty-three consecutive patients with multiple myeloma who underwent stem cell

Accuracy of sentinel lymph node detection following intra-operative cervical injection for endometrial cancer: a prospective study.

Jeffrey How et al.

Gynecologic oncology, 127(2), 332-337 (2012-08-23)

The objective of this study is to evaluate the detection rate and diagnostic accuracy of sentinel lymph node (SLN) mapping using intra-operative cervical injection of filtered 99mTc-sulfur colloid (99mTc-SC) and patent blue in patients with endometrial cancer. Prospective evaluation of

Thoracic Endovascular Aortic Repair for Type B Acute Aortic Dissection Complicated by Descending Thoracic Aneurysm.

G Piffaretti et al.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 53(6), 793-801 (2017-03-28)

To analyse the results and review the literature about thoracic aortic endovascular repair (TEVAR) for type B acute aortic dissection (TBAAD) complicated by descending thoracic aortic aneurysm (DTA) in the hyperacute or acute phases. This was a multicentre, observational descriptive

Treatment and outcomes in undifferentiated and dedifferentiated endometrial carcinoma.

Sarah Nicole Hamilton et al.

Journal of gynecologic oncology, 33(3), e25-e25 (2022-02-08)

Undifferentiated and dedifferentiated endometrial carcinoma is a rare type of uterine malignancy. This study assesses disease characteristics, treatment and survival outcomes in patients with undifferentiated and dedifferentiated endometrial carcinoma treated at BC Cancer. All patients diagnosed with undifferentiated and dedifferentiated

Characteristics of an autologous leukocyte and platelet-rich fibrin patch intended for the treatment of recalcitrant wounds.

Rasmus Lundquist et al.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 21(1), 66-76 (2012-12-13)

We have investigated the physical, biochemical, and cellular properties of an autologous leukocyte and platelet-rich fibrin patch. This was generated in an automated device from a sample of a patient's blood at the point of care. Using microscopy, cell counting

Efficacy and safety of dasatinib with trastuzumab and paclitaxel in first line HER2-positive metastatic breast cancer: results from the phase II GEICAM/2010-04 study.

Alberto Ocana et al.

Breast cancer research and treatment, 174(3), 693-701 (2019-01-05)

An important proportion of HER2-positive metastatic breast cancer patients do not respond to trastuzumab. The combination of dasatinib and trastuzumab has shown to be synergistic in preclinical models. We conducted a phase II trial combining dasatinib 100 mg once daily with

1/12