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G E Hanks et al.
International journal of radiation oncology, biology, physics, 13(4), 499-505 (1987-04-01)
This report extends the follow-up of patients studied in the Patterns of Care Survey of Prostate Cancer treated in the United States between 1973 and 1975 from a maximum of 5 years to a maximum of 10 years. Survival for
B Mertens et al.
Gene, 176(1-2), 273-274 (1996-10-17)
The nucleotide (nt) sequence encoding the bovine homologue of interleukin-5 (boIL-5) was determined. Total cDNA generated from stimulated bovine peripheral blood lymphocytes was used to amplify the boIL-5 gene using primers based on the 5' and 3' untranslated regions of
Chia-Yuan Chang et al.
Bioresource technology, 102(9), 5325-5330 (2010-12-31)
This study investigated the feasibility and the treatment efficiency of a cyclic anoxic/aerobic two-stage MBR for treating polymeric industrial wastewater. The anoxic/aerobic hybrid MBR was operated without sludge withdrawal except sampling during the study. The results showed that the highest
D Oliva et al.
Gene, 79(2), 355-360 (1989-07-15)
The nucleotide sequence of the human gamma-enolase mRNA was determined from recombinant cDNA clones. The sequence spans 2273 bp and includes the complete coding region of 1299 bp, a 5'-noncoding region of 74 bp and a 897-bp-long 3'-noncoding region containing
Antonio J Martín-Galiano et al.
Antimicrobial agents and chemotherapy, 47(10), 3187-3194 (2003-09-25)
Two clinical isolates of viridans group streptococci (VS) with different degrees of susceptibility to optochin (OPT), i.e., fully OPT-susceptible (Opt(s)) VS strain 1162/99 (for which the MIC was equal to that for Streptococcus pneumoniae, 0.75 micro g/ml) and intermediate Opt(s)
Jari Karhukorpi et al.
Journal of medical microbiology, 63(Pt 1), 34-37 (2013-09-28)
Aesculin hydrolysis (ESC) is one of the key reactions in differentiating pathogenic Yersinia enterocolitica biotypes 1B, 2, 3, 4 and 5 from the less-pathogenic biotype 1A. Because the ESC reaction is caused by β-glucosidase (βGLU) activity of the bacteria, we
Wendy Pollock et al.
Journal of immunological methods, 347(1-2), 19-23 (2009-06-06)
Most laboratories screen for antineutrophil cytoplasmic antibodies (ANCA) with indirect immunofluorescence (IIF) and confirm cytoplasmic (C-ANCA) and perinuclear (P-ANCA) staining with ELISAs for proteinase 3 (PR3) and myeloperoxidase (MPO) specificities. This study determined the concordance of ANCA test results from
Kaoru Miyahara et al.
Free radical research, 38(1), 87-95 (2004-04-06)
The endothelial nitric-oxide synthase (eNOS) gene is constitutively expressed in endothelial cells, but numerous regulatory elements in the promoter region should contribute to the regulation for cell specific expression and the response to exogenous stimuli. A Sp1-binding consensus motif (-104
Lee Ridley et al.
Neuro-oncology, 10(5), 675-689 (2008-08-15)
Pediatric ependymomas are enigmatic tumors, and their clinical management remains one of the more difficult in pediatric oncology. The identification of biological correlates of outcome and therapeutic targets remains a significant challenge in this disease. We therefore analyzed a panel
Joaquim Carreras et al.
Blood, 108(9), 2957-2964 (2006-07-11)
The tumor microenvironment plays an important role in the biologic behavior of follicular lymphoma (FL), but the specific cell subsets involved in this regulation are unknown. To determine the impact of FOXP3-positive regulatory T cells (Tregs) in the progression and
L V Filatova et al.
Voprosy onkologii, 59(2), 59-65 (2013-07-03)
In a retrospective study during the primary mode MOPP to primary patients LH II/IVAB stages with a poor prognosis rate of CR, 5--and 10-year DFS, OS was 69%, 71% and 68%, 74% and 64%, ABVD--76%, 78%, 83% and 68%, BEACOPP-baseline--73%
Naidu M Vegi et al.
Scientific reports, 10(1), 371-371 (2020-01-17)
Acute myeloid leukemia (AML) is characterized by relapse and treatment resistance in a major fraction of patients, underlining the need of innovative AML targeting therapies. Here we analysed the therapeutic potential of an innovative biohybrid consisting of the tumor-associated peptide
Aimee S Browne et al.
Fertility and sterility, 98(3), 713-719 (2012-06-22)
To evaluate neurotrophin (NT) expression in the endometrium of women with and without endometriosis. Prospective, cross-sectional, translational study. Academic hospital. Thirty-three reproductive-age women undergoing laparoscopy for infertility, pelvic pain, intramural fibroids, or tubal ligation. Endometrial biopsies, protein microarrays, reverse transcriptase-polymerase
Pervez Ahmad et al.
Bioorganic & medicinal chemistry, 24(8), 1898-1908 (2016-03-19)
A series of pyrazoline derivatives (5) were synthesized in 92-96% yields from chalcones (3) and hydrazides (4). Subsequently, topo-I and IIα-mediated relaxation and antiproliferative activity assays were evaluated for 5. Among the tested compounds, 5h had a very strong topo-I
Shozo Yamada et al.
Journal of neurosurgery, 121(6), 1462-1473 (2014-09-23)
The aim of this study was to analyze clinicopathological characteristics and treatment outcomes in a large single-center clinical series of cases of thyrotropin (TSH)-secreting pituitary adenomas. The authors retrospectively reviewed clinical, pathological, and treatment characteristics of 90 consecutive cases of
L C Russell et al.
The Journal of biological chemistry, 274(29), 20060-20063 (1999-07-10)
The sequential binding of heat shock protein 90 (hsp90) to a series of tetratricopeptide repeat (TPR) proteins is critical to its function as a molecular chaperone. We have used site-directed mutagenesis to clarify the structural basis for the binding of
Hisako Sakuma et al.
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 52(4), 220-225 (2011-08-30)
A rapid, sensitive convenient method for determination of aflatoxin M₁ (AFM₁) in cheese and butter by HPLC was developed and validated. The method employs a safe extraction solution (mixture of acetonitrile, methanol and water) and an immunoaffinity column (IAC) for
Punit Sharma et al.
Clinical nuclear medicine, 40(7), e351-e356 (2015-03-19)
The aim of this study was to evaluate the role of ⁶⁸Ga DOTANOC PET/CT imaging in patients with multiple endocrine neoplasia (MEN) syndromes. Data of 33 patients (age, 33.5 [13.8] years; male 14/female 19) with MEN syndromes (MEN 1, 9;
T T Huang et al.
Molecular and cellular endocrinology, 152(1-2), 21-35 (1999-08-04)
Interleukin-1 has been shown to contribute to infection-induced inflammatory processes during pregnancy. Prior work from this laboratory has demonstrated that serotonin-induced IL-1alpha also is required for the in-vitro production of collagenase in uterine smooth muscle cells, a normal, non-inflammatory process
Hiromu Inai et al.
Japanese journal of clinical oncology, 43(12), 1249-1254 (2013-10-09)
To investigate the dose intensity of induction chemotherapy and oncological outcomes of metastatic testicular cancer under centralized management through a regional medical network. We retrospectively analyzed the outcomes of 86 metastatic testicular cancer patients who were given induction chemotherapy at
Jérôme Harambat et al.
Kidney international, 77(5), 443-449 (2009-12-18)
We sought to ascertain the long-term outcome and genotype-phenotype correlations available for primary hyperoxaluria type 1 in a large retrospective cohort study. We examined the clinical history of 155 patients (129 families primarily from Western Europe, North Africa, or the
J Reiterová et al.
Folia biologica, 53(4), 134-137 (2007-08-21)
ADPKD is the most common hereditary renal disease. IGAN is a mesangial proliferative glomerulonephritis characterized by diffuse mesangial deposition of immunoglobulin A. ET-1 has been suggested to be a major disease-promoting factor in renal diseases. The vasoconstrictor effect of ET-1
Paola De Rango et al.
Annals of vascular surgery, 32, 73-82 (2016-01-24)
Age is a main risk factor for stroke and perioperative risk. This study aims to analyze the effect of age by symptomatic status in young patients receiving carotid revascularization. Consecutive carotid revascularization procedures performed during the period 2001-2009 were reviewed.
Neuropeptide coding of sympathetic preganglionic neurons; focus on adrenally projecting populations.
N N Kumar et al.
Neuroscience, 170(3), 789-799 (2010-08-03)
Chemical coding of sympathetic preganglionic neurons (SPN) suggests that the chemical content of subpopulations of SPN can define their function. Since neuropeptides, once synthesized are transported to the axon terminal, most demonstrated chemical coding has been identified using immunoreactive terminals
Santiago Palacio et al.
International journal of stroke : official journal of the International Stroke Society, 10(5), 686-691 (2013-05-23)
It remains controversial whether dual antiplatelet therapy reduces stroke more than aspirin alone. We aimed to assess the effects of adding clopidogrel to aspirin on the occurrence of stroke and major haemorrhage in patients with vascular disease. Meta-analysis of published
Cédric Daubin et al.
BMC cardiovascular disorders, 11, 48-48 (2011-08-10)
The prediction of neurological outcome in comatose patients after cardiac arrest has major ethical and socioeconomic implications. The purpose of this study was to assess the capability of serum neuron-specific enolase (NSE), a biomarker of hypoxic brain damage, to predict
Runzeng Liu et al.
Environmental pollution (Barking, Essex : 1987), 221, 227-233 (2016-12-06)
In this study, seven synthetic phenolic antioxidant (SPA) analogues were positively found in urban and rural indoor dust samples collected from Shandong province in China, among which the novel 2,4,6-tri-tert-butylphenol (AO 246), 2,6-di-tert-butyl-4-sec-butylphenol (DTBSBP), 2,4-di-tert-butylphenol (DBP) and 4,4'-butylidenebis (2-(1,1-dimethylethyl)-5- methyl-phenol)
Renate B Schnabel et al.
Lancet (London, England), 386(9989), 154-162 (2015-05-12)
Comprehensive long-term data on atrial fibrillation trends in men and women are scant. We aimed to provide such data through analysis of the Framingham cohort over 50 years. We investigated trends in incidence, prevalence, and risk factors for atrial fibrillation
Rosa Perestrelo et al.
Journal of chromatography. A, 1381, 54-63 (2015-01-27)
An improved, reliable and powerful analytical strategy based on digitally controlled microextraction by packed sorbent (MEPS) combined with ultrahigh pressure liquid chromatography (UHPLC) was validated for the simultaneous identification and quantification of major furanic derivatives, namely 5-hydroxymethyl-2-furaldehyde (5HMF), 5-methyl-2-furaldehyde (5MF)
Shao Hui Huang et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 144, 13-22 (2019-11-12)
This study examines outcome heterogeneity and potential to refine the TNM-8 cN-classification using radiologic extranodal extension (rENE) in a contemporary HPV-positive (HPV+) oropharyngeal carcinoma (OPC) cohort. All HPV+ OPC treated with definitive IMRT from 2010-2015 were included. Pre-treatment CT/MR of
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