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显示 31-60 共 89 条结果 关于 "98-37-3" 范围 论文
Rodica Doaga et al.
Mikrochimica acta, 187(4), 225-225 (2020-03-15)
Synthesis and functionalization of magnetite nanoparticles (Fe3O4) was achieved with the view to covalently bind both cholesterol oxidase and cholesterol esterase biorecognition agents for the development of free and total cholesterol biosensors. Prior to enzyme attachment, Fe3O4 was functionalized with
Jay K Bhattarai et al.
Nanomaterials (Basel, Switzerland), 11(1) (2021-01-21)
Nanoparticles (NPs) have been widely explored for delivering doxorubicin (DOX), an anticancer drug, to minimize cardiotoxicity. However, their efficiency is marred by a necessity to chemically modify DOX, NPs, or both and low deposition of the administered NPs on tumors.
Marek Pruszyński et al.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 70(6), 974-979 (2012-04-03)
The positron-emitting radionuclide (44)Sc with a half-life of 3.97 h and a β(+) branching of 94.3% is of potential interest for clinical PET. As so far it is available from a (44)Ti/(44)Sc generator in Mainz, where long-lived (44)Ti decays to
Erlet Shehi et al.
Biochemistry, 42(49), 14626-14632 (2003-12-10)
The protein ataxin-3 is responsible for Machado-Joseph disease/spinocerebellar ataxia type 3, a neurodegenerative disorder caused by the presence of an expanded polyglutamine tract. A previous investigation [Bevivino, A. E., and Loll, P. J. (2001) Proc. Natl. Acad. Sci. U.S.A. 98
Y P Yang et al.
Human mutation, 19(1), 82-83 (2001-12-26)
The spectrum of mutations in the Galactose-1-phosphate uridyl transferase (GALT) gene is described in 11 cases of classic galactosemia and 38 of Duarte-2 type identified by the Texas Newborn Screening Program. Blinded studies were done by automated DNA sequencing of
C Shi et al.
Epidemiology and infection, 139(5), 674-682 (2010-06-08)
Genetic polymorphisms of the LMP/TAP gene coded by the HLA-II region may be associated with outcomes of HBV infection. We conducted a case-control study to test the hypothesis, including a persistent group of 155 patients with chronic hepatitis B and
J Hilbert et al.
Drug metabolism and disposition: the biological fate of chemicals, 12(4), 452-459 (1984-07-01)
The disposition of 14C-quazepam (7-chloro-(2,2,2-trifluoroethyl) [5-14C]-5-o-fluorophenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-thione), a new benzodiazepine hypnotic, was studied in hamsters and mice after iv and po dosing. In both species, quazepam was rapidly absorbed, as indicated by the plasma Cmax being reached within 1 hr of
Ahmed A Al-Qahtani et al.
Journal of chemotherapy (Florence, Italy), 26(3), 139-145 (2013-10-05)
The objectives of this study were to determine the prevalences, genotypes, and clonal relationships of extended-spectrum beta-lactamase (ESBL)-producing strains in 98 Klebsiella pneumoniae isolates from Riyadh. The prevalence of ESBLs in these strains was 37·75%. All isolates that were confirmed
P Willeke et al.
Scandinavian journal of rheumatology, 44(4), 302-308 (2015-03-07)
To determine whether platelet (PLT) counts might serve as a biomarker to distinguish between active anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and remission and also between active disease and systemic infection. PLTs were analysed before treatment in patients with AAV
Georgina V Long et al.
The American journal of surgical pathology, 37(1), 61-65 (2012-10-03)
This study investigated the sensitivity and specificity of immunohistochemical (IHC) analysis using an anti-BRAF antibody to detect the presence of the BRAF V600E mutation in patients with metastatic melanoma. A total of 100 patients with American Joint Committee on Cancer
K O Schoeps et al.
Nuclear medicine and biology, 20(5), 669-678 (1993-07-01)
A method for no-carrier-added 1-11C-labelling of 3-hydroxy-, 4-hydroxy- and 3,4-dihydroxy-substituted phenethylamines is described. [11C]Dopamine, [11C]p-tyramine and [11C]m-tyramine were prepared from on-line produced [11C]nitromethane. Condensation of [11C]nitromethane with various protected and unprotected benzaldehydes was investigated. A one-pot two-step reduction of the
Carla G Monico et al.
Journal of the American Society of Nephrology : JASN, 18(6), 1905-1914 (2007-04-27)
Mutations in AGXT, a locus mapped to 2q37.3, cause deficiency of liver-specific alanine:glyoxylate aminotransferase (AGT), the metabolic error in type 1 primary hyperoxaluria (PH1). Genetic analysis of 55 unrelated probands with PH1 from the Mayo Clinic Hyperoxaluria Center, to date
K J Langen et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 41(7), 1250-1255 (2000-07-29)
The amino acid analog 3-[(123)I]iodo-alpha-methyl-L-tyrosine (IMT) is under clinical evaluation as a SPECT tracer of amino acid transport in brain tumors. This study investigated the carrier systems involved in IMT transport in human glioma cells in comparison with [3H-methyl]-L-methionine (3H-MET).
M Victoria Sanz Fernandez et al.
Temperature (Austin, Tex.), 1(2), 128-134 (2014-07-01)
Heat stress compromises intestinal integrity which may partially explain its negative effects on animal health and productivity. Research suggests that challenged intestinal barrier function improves with dietary dairy products in various models. Thus, the study objective was to evaluate the
José Garnacho-Montero et al.
Diagnostic microbiology and infectious disease, 73(1), 39-44 (2012-05-15)
Studies evaluating associations between polymorphisms of innate immunity genes and prognosis of infectious diseases have yielded conflicting results. Our aim was to assess the impact on mortality of different genotypic variants of the innate immunity in patients with pneumococcal sepsis.
L Gijsbers et al.
Journal of human hypertension, 29(10), 592-598 (2015-02-13)
We performed a randomised, placebo-controlled, crossover study to examine the effects of sodium and potassium supplementation on blood pressure (BP) and arterial stiffness in untreated (pre)hypertensive individuals. During the study, subjects were on a fully controlled diet that was relatively
Waseem J David et al.
Gastrointestinal endoscopy, 82(5), 793-803 (2015-06-14)
There are few data comparing endoscopic treatment outcomes for Barrett's esophagus (BE). To compare treatment outcomes in BE patients treated with radiofrequency ablation (RFA), RFA after EMR, and porfimer sodium photodynamic therapy (Ps-PDT). Retrospective, observational study. Single tertiary center between
Hiroaki Nishimatsu et al.
Circulation research, 90(6), 657-663 (2002-04-06)
Adrenomedullin (AM) is a potent depressor peptide whose vascular action is suggested to involve nitric oxide (NO) release. To explore the role of endogenous AM in vascular and renal function, we examined the effects of acetylcholine (ACh), AM, and AM
Nadine Puget et al.
American journal of human genetics, 70(4), 858-865 (2002-03-07)
The 5' end of the breast and ovarian cancer-susceptibility gene BRCA1 has previously been shown to lie within a duplicated region of chromosome band 17q21. The duplicated region contains BRCA1 exons 1A, 1B, and 2 and their surrounding introns; as
Sophie Colliard et al.
Arthritis care & research, 70(8), 1263-1268 (2017-10-19)
Systemic lupus erythematosus (SLE) is a multisystem inflammatory disease characterized by the production of various autoantibodies. The aim of this study was to investigate the presence of anti-ficolin-2 antibodies in SLE patients and to evaluate the association between the levels
Lisa C Costello-Boerrigter et al.
Mayo Clinic proceedings, 86(3), 210-218 (2011-03-03)
To assess in a US general adult population the effect of the functional single-nucleotide polymorphism rs198389 in the promoter region of the gene of brain-type natriuretic peptide (BNP) on 3 commonly used BNP assays, clinical phenotype, disease prevalence, overall survival
Jingdong Zhang et al.
International journal of clinical and experimental pathology, 4(4), 356-362 (2011-05-18)
Papillary thyroid cancer (PTC) has an impressive propensity for lymphatic spread. Signal transducers and activators of transcription 3 (STAT3), constitutively activated in many different cancers, may play a role in PTC lymphatic metastases. We examined 49 patients with PTC, 22
Matthew Miller et al.
Journal of prosthodontics : official journal of the American College of Prosthodontists, 27(8), 737-740 (2018-02-20)
To evaluate bicuspid axial wall height effect on the fracture mode of adhesively luted, all-ceramic CAD/CAM crowns with a 20° total occlusal convergence (TOC). Recently extracted premolars were randomly divided into 4 groups (n = 12) with all-ceramic crown preparations
Betina Durovni et al.
PLoS medicine, 11(12), e1001766-e1001766 (2014-12-10)
Abundant evidence on Xpert MTB/RIF accuracy for diagnosing tuberculosis (TB) and rifampicin resistance has been produced, yet there are few data on the population benefit of its programmatic use. We assessed whether the implementation of Xpert MTB/RIF in routine conditions
J DiPersio et al.
The Journal of biological chemistry, 263(4), 1834-1841 (1988-02-05)
Human granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine derived from activated T cells, endothelial cells, fibroblasts, and macrophages. It stimulates myeloid and erythroid progenitors to form colonies in semisolid medium in vitro, as well as enhancing multiple differentiated functions of
Andreas Brink et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 830(2), 255-261 (2005-11-22)
O(6)-Methyl-2'-deoxyguanosine (O(6)-mdGuo), 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo), and 1,N(6)-etheno-2'-deoxyadenosine (epsilondAdo) are promutagenic DNA lesions originating from both endogenous and exogenous agents and actions (methylation, hydroxylation, lipid peroxidation products). A highly sensitive quantitative method was developed to measure these DNA adducts simultaneously, using liquid
Sina Kavalakatt et al.
Frontiers in endocrinology, 10, 762-762 (2019-11-30)
Urocortin3 (UCN3) regulates metabolic functions and is involved in cellular stress response. Although UCN3 is expressed in human adipose tissue, the association of UCN3 with obesity and diabetes remains unclear. This study investigated the effects of Type 2 diabetes (T2D)
Aneesa Noormohamed et al.
Foodborne pathogens and disease, 9(7), 617-624 (2012-05-02)
Campylobacter species are one of the leading causes of foodborne disease in the United States. Campylobacter jejuni and Campylobacter coli are the two main species that are of concern to human health, and they cause approximately 95% of human infections.
Ramin Sam et al.
Clinical and experimental nephrology, 19(3), 395-402 (2014-07-06)
Membranous glomerulonephritis is typically classified as idiopathic or secondary to systemic lupus erythematosus (SLE), hepatitis B, drugs, toxins, other infections, or malignancy. Not infrequently in some patients without a definite diagnosis of SLE, pathologic features of secondary membranous nephropathy are
Isabelle Trouilloud et al.
European journal of cancer (Oxford, England : 1990), 50(18), 3116-3124 (2014-12-03)
Fluorouracil and irinotecan-based, and gemcitabine-based regimens, are the standard of care in the first-line treatment of patients with metastatic pancreatic cancer. New approaches are needed to improve survival and quality of life. Whether a sequential approach alternating irinotecan, fluorouracil and
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