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关键词:'A5533'
显示 1-30 共 231 条结果 关于 "A5533" 范围 论文
Mekayla A Storer et al.
Developmental cell, 52(4), 509-524 (2020-01-07)
Here, we investigate the origin and nature of blastema cells that regenerate the adult murine digit tip. We show that Pdgfra-expressing mesenchymal cells in uninjured digits establish the regenerative blastema and are essential for regeneration. Single-cell profiling shows that the
Christos Pandis et al.
Macromolecular bioscience, 15(2), 262-274 (2014-10-11)
A novel approach to reinforce polymer porous membranes is presented. In the prepared hybrid materials, the inorganic phase of silica is synthesized in-situ and inside the pores of aminolyzed polylactic acid (PLA) membranes by sol-gel reactions using tetraethylorthosilicate (TEOS) and
Ramon E Coronado et al.
Stem cell research, 38, 101471-101471 (2019-06-05)
Transplantation of primary hepatocytes has been used in treatments for various liver pathologies and end-stage liver disease. However, shortage of donor tissue and the inability of hepatocyte proliferation in vitro have lead to alternative methods such as stem cell-derived hepatocyte-like
Theresa Pohlkamp et al.
PloS one, 10(2), e0116701-e0116701 (2015-02-18)
Apolipoprotein E (ApoE) genotype is the strongest predictor of Alzheimer's Disease (AD) risk. ApoE is a cholesterol transport protein that binds to members of the Low-Density Lipoprotein (LDL) Receptor family, which includes LDL Receptor Related Protein 4 (Lrp4). Lrp4, together
Hong Chen et al.
Science advances, 6(15), eaay1514-eaay1514 (2020-04-15)
Dental pulp is critical to maintain the vitality of a tooth. Regeneration of pulpo-dentinal complex is of great interest to treat pulpitis and pulp necrosis. In this study, through three-dimensional spheroid culture, a group of unique multipotent stem cells were
Wahyu Widowati et al.
International journal of molecular and cellular medicine, 8(4), 283-294 (2020-06-27)
Mesenchymal stem cells (MSCs) have unique properties, including high proliferation rates, self-renewal, and multilineage differentiation ability. Their characteristics are affected by increasing age and microenvironment. This research is aimed to determine the proliferation, characteristics and differentiation capacity of adipose tissue-derived
Kian F Eichholz et al.
Advanced healthcare materials, 9(24), e2001102-e2001102 (2020-10-29)
The hierarchical structure of bone plays pivotal roles in driving cell behavior and tissue regeneration and must be considered when designing materials for orthopedic applications. Herein, it is aimed to recapitulate the native bone environment by using melt electrowriting to
Jana C Blum et al.
Journal of tissue engineering, 12, 20417314211022242-20417314211022242 (2021-07-16)
Ideal tissue engineering frameworks should be both an optimal biological microenvironment and a shape and stability providing framework. In this study we tried to combine the advantages of cell-derived artificial extracellular matrix (ECM) with those of 3D printed polycaprolactone (PCL)
Meizhu Bai et al.
PLoS biology, 17(7), e3000350-e3000350 (2019-07-03)
Mutagenic screening is powerful for identifying key genes involved in developmental processes. However, such screens are successful only in lower organisms. Here, we develop a targeted genetic screening approach in mice through combining androgenetic haploid embryonic stem cells (AG-haESCs) and
Karim Benabdellah et al.
PloS one, 6(8), e23734-e23734 (2011-08-31)
Lentiviral vectors (LVs) are considered one of the most promising vehicles to efficiently deliver genetic information for basic research and gene therapy approaches. Combining LVs with drug-inducible expression systems should allow tight control of transgene expression with minimal side effect
Christopher D Kegelman et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(5), 2706-2721 (2018-02-07)
The functions of the paralogous transcriptional coactivators Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) in bone are controversial. Each has been observed to promote or inhibit osteogenesis in vitro, with reports of both equivalent and divergent functions.
Stain Technology, 16, 23-23 (1941)
Preety Dixit et al.
Phytochemistry, 81, 117-125 (2012-07-13)
Phytochemical investigation of seed coats of Pterospermum acerifolium afforded two phytoceramides (1, 2) and two acylated phytosterol glucosides (3, 4) together with five known compounds (5-9). Their structures were elucidated on the basis of extensive spectroscopic analysis using 1D, 2D
Nicolás Cumplido et al.
Frontiers in zoology, 17, 18-18 (2020-06-10)
With more than 30,000 species, teleosts comprise about half of today's living vertebrates, enriched with a wide set of adaptations to all aquatic systems. Their evolution was marked by modifications of their tail, that involved major rearrangements of the metameric
Elisa Mazzoni et al.
Stem cells translational medicine, 9(3), 377-388 (2019-12-14)
Tissue engineering-based bone graft is an emerging viable treatment modality to repair and regenerate tissues damaged as a result of diseases or injuries. The structure and composition of scaffolds should modulate the classical osteogenic pathways in human stem cells. The
RGD peptides immobilized on a mechanically deformable surface promote osteoblast differentiation.
Cavalcanti-Adam EA, et al.
Journal of Bone and Mineral Research, 17, 2130-2130 (2002)
On the history and mechanism of alizarin and alizarin red S stains for calcium.
Puchtler H, et al.
The Journal of Histochemistry and Cytochemistry, 17, 110-124 (1969)
Dengjun Wang et al.
Environmental science & technology, 46(5), 2738-2745 (2012-02-10)
Hydroxyapatite nanoparticles (nHAP) have been widely used to remediate soil and wastewater contaminated with metals and radionuclides. However, our understanding of nHAP transport and fate is limited in natural environments that exhibit significant variability in solid and solution chemistry. The
Markus Neubauer et al.
Stem cells international, 2019, 1358267-1358267 (2020-02-23)
Adipose-derived mesenchymal stem cells (AD-MSCs) from fat tissue considered "surgical waste" during joint surgery may provide a potent source for regenerative medicine. Intra-articular, homologous fat tissue (Hoffa's fat pad, pouch fat) might possess a superior chondrogenic and osteogenic differentiation potential
Michela Battistelli et al.
European journal of histochemistry : EJH, 63(1) (2019-02-12)
The human meniscus plays a crucial role for transmission and distribution of load across the knee, as well as shock absorption, joint stability, lubrication, and congruity. The aim of this study was to compare the complex geometry, and unique ultrastructure
Zhanguang Chen et al.
Biosensors & bioelectronics, 38(1), 202-208 (2012-06-27)
In this study, a new type of rapid, high sensitive and selective fluorescence turn-on assay for detection of glutathione using an Alizarin Red S/copper ion ensemble is developed. This assay is based on the highly specific interaction between the glutathione
D-H Xu et al.
Journal of fish diseases, 35(12), 887-895 (2012-08-24)
This study compared the susceptibility of three blue catfish strains (D&B, USDA 101 and USDA 102) to the parasite Ichthyophthirius multifiliis (Ich). In Trial I, a cohabitation study (all strains stocked communally) was conducted and fish were exposed to theronts
Miriam Filippi et al.
Materials (Basel, Switzerland), 14(17) (2021-09-11)
By permeabilizing the cell membrane with ultrasound and facilitating the uptake of iron oxide nanoparticles, the magneto-sonoporation (MSP) technique can be used to instantaneously label transplantable cells (like stem cells) to be visualized via magnetic resonance imaging in vivo. However
Jun Wu et al.
Cell research, 30(9), 794-809 (2020-06-18)
Lung injury and fibrosis represent the most significant outcomes of severe and acute lung disorders, including COVID-19. However, there are still no effective drugs to treat lung injury and fibrosis. In this study, we report the generation of clinical-grade human
Stain Technology, 1, 123-123 (1926)
Maurycy Jankowski et al.
International journal of molecular sciences, 22(13) (2021-07-03)
Next-generation sequencing (RNAseq) analysis of gene expression changes during the long-term in vitro culture and osteogenic differentiation of ASCs remains to be important, as the analysis provides important clues toward employing stem cells as a therapeutic intervention. In this study
Chong Yin et al.
Journal of cellular physiology, 234(7), 11524-11536 (2019-01-19)
The incidence of postmenopausal osteoporosis research 50% in middle-aged and older women, however, effects of existing therapy are not ideal. Emerging evidence have proved that long noncoding RNAs (lncRNAs) was correlated with multiple physiological and pathology processes including development, carcinogenesis
Zahra Alvandi et al.
PloS one, 15(11), e0241646-e0241646 (2020-11-13)
The proto-oncogene Src is ubiquitously expressed and is involved in cellular differentiation. However, the role of Src in embryonic stem (ES) cell osteogenic differentiation is largely unknown. Using the small molecule inhibitor PP2, c-Src specific siRNAs, and tet-inducible lentiviral vectors
Adam M Zahm et al.
Bone, 43(1), 25-31 (2008-05-20)
Oxygen availability is a critical signal for proper development of many tissues, however there is limited knowledge of its role in the maturation of bone cells. To test the hypothesis that low pO2 regulates bone cell mineralization, MLO-A5 and MLO-Y4
Xijuan Xiao et al.
BioMed research international, 2020, 3871496-3871496 (2021-01-26)
The repair of dental pulp injury relies on the odontogenic differentiation of dental pulp stem cells (DPSCs). To better understand the odontogenic differentiation of DPSCs and identify proteins involved in this process, tandem mass tags (TMTs) coupled with liquid chromatography-tandem
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