AMAB90627

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关键词:'AMAB90627'

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HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5.

Inga Newie et al.

Scientific reports, 6, 35664-35664 (2016-10-19)

We previously reported that the human HER2 gene encodes the intronic microRNA mir-4728, which is overexpressed together with its oncogenic host gene and may act independently of the HER2 receptor. More recently, we also reported that the oncogenic miR-21-5p is

HER2: biology, detection, and clinical implications.

Gutierrez C and Schiff R.

Archives of Pathology & Laboratory Medicine, 135(1), 55-62 (2011)

Fast and Efficient Fc-Specific Photoaffinity Labeling To Produce Antibody-DNA Conjugates.

Christiane Stiller et al.

Bioconjugate chemistry, 30(11), 2790-2798 (2019-10-15)

Antibody-DNA conjugates are powerful tools for DNA-assisted protein analysis. Growing usage of these methods demands efficient production of high-quality conjugates. We developed an easy and fast synthesis route yielding covalent antibody-DNA conjugates with a defined conjugation site and low batch-to-batch

The role of p95HER2 in trastuzumab resistance in breast cancer.

Ozkavruk Eliyatkin N, et al.

Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology, 21(2), 382-389 (2016)

A rational mouse model to detect on-target, off-tumor CAR T cell toxicity.

Mauro Castellarin et al.

JCI insight, 5(14) (2020-06-17)

Off-tumor targeting of human antigens is difficult to predict in preclinical animal studies and can lead to serious adverse effects in patients. To address this, we developed a mouse model with stable and tunable human Her2 (hHer2) expression on normal

HER2 expression beyond breast cancer: therapeutic implications for gynecologic malignancies.

English DP, et al.

Molecular Diagnosis & Therapy, 17(2), 85-99 (2013)

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