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Mercedes Ibáñez et al.
Diseases of the colon and rectum, 54(12), 1578-1584 (2011-11-10)
No consensus exists regarding the optimal bowel preparation regimen for patients with poor bowel cleansing at a previous colonoscopy. We investigated the usefulness of an intensive cleansing regimen for repeat colonoscopy after previous failure of bowel preparation. A prospective observational
Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk (2011)
A Repici et al.
Alimentary pharmacology & therapeutics, 36(8), 717-724 (2012-08-29)
Low-volume bowel preparations with polyethylene glycol (PEG) have been shown to provide an equivalent cleansing with improved tolerability as compared with standard PEG bowel preparation for colonoscopy. A new iso-osmotic sulphate-free formulation of PEG-Citrate-Simethicone (PEG-CS) in combination with bisacodyl has
An interesting case of bisacodyl (dulcolax)-induced chromhidrosis.
A S Krishnaram et al.
Indian journal of dermatology, venereology and leprology, 78(6), 756-758 (2012-10-19)
Eduardo Coghlan et al.
Acta gastroenterologica Latinoamericana, 42(3), 186-192 (2012-12-12)
Most comparative studies on different preparations for colonic cleanliness use unvalidated scales with terms as "excellent," "good," "fair," and "poor" which lack standardized definitions. The Boston Bowel Preparation Scale (BBPS) is a valid and simple measure of bowel preparation. To
V Giorgio et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 25(1), 70-78 (2012-10-04)
Severe pediatric slow transit constipation (STC) is commonly due to intrinsic colonic neuromuscular disease. We sought to correlate neuromuscular histological phenotypes in pediatric STC with colonic manometric phenotypes using high-resolution manometry (HRM). We tested the hypothesis that failure of motor
Frederick K Shieh et al.
Journal of clinical gastroenterology, 46(10), e96-e100 (2012-10-13)
Polyethylene glycol-3350 without electrolytes (MiraLAX; Schering-Plough Healthcare Products Inc.)+a carbohydrate-electrolyte solution (Gatorade; PepsiCo Inc.)+bisacodyl is frequently used for bowel cleansing, although limited data quantifies its efficacy and safety. No prior studies have assessed this in a community setting or with
Uma P Phatak et al.
Journal of pediatric gastroenterology and nutrition, 53(1), 71-74 (2011-06-23)
To assess the safety, efficacy, and acceptance of a 2-day bowel preparation with polyethylene glycol (PEG) 3350 without electrolytes and bisacodyl for colonoscopy in children. In a prospective study, 111 children of mean age 11.9 years were given 2 g/kg
Manoel Carlos Vieira et al.
Arquivos de gastroenterologia, 49(2), 162-168 (2012-07-07)
Colonoscopy is currently the gold standard method to examine the colon, the rectum and the terminal ileum. In order to perform the colonoscopy, it is necessary to clean the bowel and use medications that are generally poorly tolerated by the
Desk Reference of Clinical Pharmacology, Second Edition (2007)
Michael A Kamm et al.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 9(7), 577-583 (2011-03-29)
Although stimulant laxatives have been used for many years to treat patients with constipation, their clinical value has been questioned, and there have been few high-quality trials to assess their efficacy. We tested the efficacy and safety of 4 weeks
Dima Ghanam et al.
International journal of pharmaceutics, 409(1-2), 9-18 (2011-02-22)
κ-Carrageenan is a novel pelletisation aid with high formulation robustness and quick disintegration leading to fast drug release unlike the matrix-like release from non-disintegrating microcrystalline cellulose pellets. Compression of pellets into tablets is cost effective. The feasibility of formulating multiparticulate
Philip O Katz et al.
The American journal of gastroenterology, 108(3), 401-409 (2013-01-16)
Optimal bowel preparation is vital for the efficacy and safety of colonoscopy. The inconvenience, discomfort, required consumption of large volumes of product, and potential adverse effects associated with some bowel preparations deter patients from colonoscopy and may provide inadequate cleansing.
Commentary: low-volume bowel preparation for colonoscopy - authors' reply.
A Repici et al.
Alimentary pharmacology & therapeutics, 36(10), 989-989 (2012-10-18)
Aleksandra S Chikina et al.
Cell, 183(2), 411-428 (2020-09-25)
The colon is primarily responsible for absorbing fluids. It contains a large number of microorganisms including fungi, which are enriched in its distal segment. The colonic mucosa must therefore tightly regulate fluid influx to control absorption of fungal metabolites, which
Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the US multi-society task force on colorectal cancer.
David A Johnson et al.
Gastroenterology, 147(4), 903-924 (2014-09-23)
Seeking the ultimate bowel preparation for colonoscopy: is the end in sight?
Robert Jay Hilsden
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 655-656 (2011-12-17)
Paola Cesaro et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 45(1), 23-27 (2012-08-25)
4-L polyethylene glycol preparations are effective for colon cleansing before colonoscopy. However, large volume and unpleasant taste reduce tolerability and acceptability limiting patient compliance. A new isosmotic low-volume polyethylene glycol preparation with citrates and simethicone plus bisacodyl has been developed
Optimizing adequacy of bowel cleansing for colonoscopy: recommendations from the U.S. multi-society task force on colorectal cancer.
David A Johnson et al.
Gastrointestinal endoscopy, 80(4), 543-562 (2014-09-16)
Commentary: low-volume bowel preparation for colonoscopy.
L S Friedman
Alimentary pharmacology & therapeutics, 36(10), 988-989 (2012-10-18)
L Rodriguez et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 24(11), 1023-e545-1023-e545 (2012-07-05)
Describe the association of internal anal sphincter (IAS) relaxation with colonic high- amplitude peristaltic contractions (HAPCs). Retrospective review of colon manometry tracings of children with constipation to determine the IAS relaxation characteristics associated with HAPC's (HAPC-IASR) events and compare them
J Tack et al.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 27(3), 397-405 (2015-01-13)
Prucalopride is a high-affinity 5-HT4 receptor agonist for the treatment of chronic constipation. The aims of this study were to investigate the relationship between health-related quality of life (HRQoL) and symptoms of constipation, and to assess the response of HRQoL
A Pollentine et al.
The British journal of radiology, 85(1016), 1085-1092 (2012-03-17)
To compare a 2 day bowel preparation regime of barium, iodine and a mild stimulant laxative with a 1 day iodine-only regime for CT colonography (CTC). 100 consecutive patients underwent CTC. The first 50 patients (Regime 1) ingested 1 bisacodyl
Stephen Vanner et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 663-666 (2011-12-17)
Despite the wealth of research investigating bowel cleansing efficacy, there are very little data on the timing or frequency of bowel movements after each agent is ingested. To examine the effect of each component of a three-day combined sodium picosulphate⁄magnesium
Dina Kao et al.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 25(12), 657-662 (2011-12-17)
The ideal bowel cleansing regimen for colonoscopy has yet to be determined. To compare the cleansing efficacy, and patient tolerability and safety of four bowel preparation regimens. A total of 834 patients undergoing outpatient colonoscopy were randomly assigned to one
Nobutomo Ikarashi et al.
American journal of physiology. Gastrointestinal and liver physiology, 301(5), G887-G895 (2011-08-27)
The purpose of this study was to investigate the role of aquaporin3 (AQP3) in the colon in the laxative effect of bisacodyl. After oral administration of bisacodyl to rats, AQP3, macrophages, cyclooxygenase 2 (COX2), and prostaglandin E(2) (PGE(2)) were examined
Christian Friedrich et al.
Drug metabolism and pharmacokinetics, 26(5), 458-464 (2011-06-24)
The aim of this study was to determine whether administration of the prodrugs bisacodyl (Bisa) and sodium picosulfate (SPS) leads to excretion of their common active metabolite, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), in breast milk. Two groups of 8 healthy lactating women who
Patient-friendly bowel preparation for colonoscopy - another brick in the wall?
Livio Cipolletta et al.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 45(1), 16-17 (2012-11-28)
Bahar Javdan et al.
Cell, 181(7), 1661-1679 (2020-06-12)
The human gut microbiome harbors hundreds of bacterial species with diverse biochemical capabilities. Dozens of drugs have been shown to be metabolized by single isolates from the gut microbiome, but the extent of this phenomenon is rarely explored in the
C Daniel Johnson et al.
Abdominal imaging, 36(6), 707-712 (2011-05-27)
We retrospectively evaluated computed tomographic colonography examinations of patients who have had a partial bowel preparation and compared the quality of their preparation with patients who have had a full bowel preparation. In total, 27 patients undergoing computed tomographic colonography
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