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显示 1-11 共 11 条结果 关于 "C2-BIOC" 范围 论文
Lukas Peintner et al.
Autophagy, 17(9), 2384-2400 (2020-09-25)
Mutations in the PKD1 gene result in autosomal dominant polycystic kidney disease (ADPKD), the most common monogenetic cause of end-stage renal disease (ESRD) in humans. Previous reports suggested that PKD1, together with PKD2/polycystin-2, may function as a receptor-cation channel complex
Tissue dissociation enzymes for adipose stromal vascular fraction cell isolation: a review
Lockhart RA, et al.
Journal of stem cell research & therapy (2015)
Julia Hesse et al.
eLife, 10 (2021-06-22)
In the adult heart, the epicardium becomes activated after injury, contributing to cardiac healing by secretion of paracrine factors. Here, we analyzed by single-cell RNA sequencing combined with RNA in situ hybridization and lineage tracing of Wilms tumor protein 1-positive
Yuan Yang et al.
Toxicology and applied pharmacology, 410, 115364-115364 (2020-12-09)
Semaphorin (Sema) 3A and Sema 4A are immunomodulatory molecules with a common receptor, neuropilin-1 (NRP-1), on the immune cells. Sema 3A binds to NRP-1 and inhibits T cell activation and inflammation, while Sema 4A binds to NRP-1 and promotes T
Zijie Zhou et al.
Aging and disease (2023-05-17)
Intervertebral disc degeneration is a leading cause of disability in the elderly population. Rigid extracellular matrix is a critical pathological feature of disc degeneration, leading to aberrant nucleus pulposus cells (NPCs) proliferation. However, the underlying mechanism is unclear. Here, we
Yu-Yao Zhang et al.
Stem cell research & therapy, 13(1), 340-340 (2022-07-27)
Nucleus pulposus mesenchymal stem cells (NPMSCs) transplantation is a promising treatment for intervertebral disc degeneration (IVDD). However, the transplanted NPMSCs exhibited weak cell proliferation, high cell apoptosis, and a low ability to resist the harsh microenvironment of the degenerated intervertebral
Yuan Yang et al.
BMC pharmacology & toxicology, 23(1), 16-16 (2022-03-23)
Arsenic, existing ubiquitously in soil, drinking water, or food, is well known to be an environmental pollutants concerned by European Food Safety Authority. Lentinan, a beta-1,6;1,3-glucan extracts from Lentinus edodes, which has the properties of antioxidant and immunomodulation, present study
Qibing Wu et al.
International journal of molecular sciences, 24(7) (2023-04-14)
Radiation-induced brain injury is a serious complication with complex pathogenesis that may accompany radiotherapy of head and neck tumors. Although studies have shown that calcium (Ca2+) signaling may be involved in the occurrence and development of radiation-induced brain injury, the
Pei-Long Liu et al.
Analytical cellular pathology (Amsterdam), 2023, 7573165-7573165 (2023-05-18)
Diabetic neuropathic osteoarthropathy (DNOAP) is a rare and easily missed complication for diabetes that leads to increased morbidity and mortality. DNOAP is characterized by progressive destruction of bone and joint, but its pathogenesis remains elusive. We herein aimed to investigate
Integrin αVβ3 Signaling in the Progression of Osteoarthritis Induced by Excessive Mechanical Stress.
Fanglong Song et al.
Inflammation, 46(2), 739-751 (2022-12-09)
Osteoarthritis (OA) is believed to be linked with cartilage degeneration, subchondral bone sclerosis, and synovial inflammation that lead to joint failure, and yet treatment that can effectively reverse the pathological process of the disease still not exists. Recent evidence suggests
Ahmad Salimi et al.
Frontiers in pharmacology, 12, 719081-719081 (2021-12-04)
Oxidative stress and mitochondrial dysfunction are involved in the mechanisms of cardiac toxicity induced by aluminum phosphide (AlP). AlP-induced cardiotoxicity leads to cardiomyocyte death, cardiomyopathy, cardiac dysfunction, and eventually severe heart failure and death. Importantly, protecting cardiomyocytes from death resulting
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