CN
Search Within
C6830
应用筛选条件
关键词:'C6830'
显示 1-30 共 35 条结果 关于 "C6830" 范围 论文
Youheng Wei et al.
Nucleic acids research, 37(19), 6550-6561 (2009-09-04)
The tight regulation of transiently expressed antimicrobial peptides (AMPs) with a distinct antimicrobial spectrum and different expression kinetics contributes greatly to the properly regulated immune response for resistance to pathogens and for the maintenance of mutualistic microbiota in Drosophila. The
Xiuqing Wang et al.
Experimental biology and medicine (Maywood, N.J.), 237(3), 312-317 (2012-03-02)
The hybrid peptide CA(1-7)-M(2-12) gene was designed according to the N-terminal 1-7 amino acid sequence of the antimicrobial peptide cecropin A (CA) and the N-terminal 2-12 amino acid sequence of maganin (M) and synthesized using Pichia pastoris preferred codons. The
Anna Junell et al.
Molecular and cellular biology, 30(14), 3672-3684 (2010-05-12)
Innate immunity operates as a first line of defense in multicellular organisms against infections caused by different classes of microorganisms. Antimicrobial peptides (AMPs) are synthesized constitutively in barrier epithelia to protect against microbial attack and are also upregulated in response
Vladimir Kokoza et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(18), 8111-8116 (2010-04-14)
To overcome burden of mosquito-borne diseases, multiple control strategies are needed. Population replacement with genetically modified mosquitoes carrying antipathogen effector genes is one of the possible approaches for controlling disease transmission. However, transgenic mosquitoes with antipathogen phenotypes based on overexpression
Jichuan Pan et al.
Gene, 549(1), 141-148 (2014-07-30)
Resistance and resilience constitute the two complementary aspects of epithelial host defenses in Drosophila. Epithelial cell homeostasis is necessary for the recovery of damages caused by stress or infections. However, the genes responsible for gut epithelial homeostasis remain poorly understood.
Effects of two hemolymph proteins on humoral defense reactions in the wax moth, Galleria mellonella.
Shin Yong Park et al.
Developmental and comparative immunology, 29(1), 43-51 (2004-08-25)
Two hemolymph proteins were isolated from the wax moth, Galleria mellonella, larvae by a two-step procedure consisting of acid extraction and reversed phase (RP)-HPLC. One was an apolipophorin III (apoLp-III) previously characterized as a lipopolysaccharide (LPS) binding protein in the
Sichen Shao et al.
Cell, 147(7), 1576-1588 (2011-12-27)
Metazoans secrete an extensive array of small proteins essential for intercellular communication, defense, and physiologic regulation. Their synthesis takes mere seconds, leaving minimal time for recognition by the machinery for cotranslational protein translocation into the ER. The pathway taken by
Sridevi Nakka et al.
Microbiological research, 165(8), 665-673 (2010-02-02)
The PhoPQ system is a pleiotropic two-component signal transduction system that controls many pathogenic properties in several mammalian and plant pathogens. Three different cues have been demonstrated to activate the PhoPQ system including a mild acidic pH, antimicrobial peptides, and
Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples.
Esther Badosa et al.
Applied and environmental microbiology, 75(17), 5563-5569 (2009-07-21)
The antifungal activity of cecropin A(2-8)-melittin(6-9) hybrid undecapeptides, previously reported as active against plant pathogenic bacteria, was studied. A set of 15 sequences was screened in vitro against Fusarium oxysporum, Penicillium expansum, Aspergillus niger, and Rhizopus stolonifer. Most compounds were
Jerzy Juśkiewicz et al.
Animals : an open access journal from MDPI, 11(5) (2021-05-01)
We hypothesised that the dietary addition of the bioactive antimicrobial protein lactoferrin (LF) and peptides melittin (MT) or cecropin A (CR) at a dosage of 100 mg/kg to the diet of Wistar rats would result in strong modulatory effects on
Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature 292: 246-248. 1981.
Håkan Steiner et al.
Journal of immunology (Baltimore, Md. : 1950), 182(11), 6635-6637 (2009-05-21)
Radu Anghel et al.
BioMed research international, 2013, 831709-831709 (2013-11-14)
Many studies have highlighted the tumoricidal properties of some natural peptides known to have antimicrobial virtues. Also, the increasingly higher resistance to conventional antibiotics has become a global public health issue, and the need for new antibiotics has stimulated interest
Diana E Schlamadinger et al.
The journal of physical chemistry. B, 116(35), 10600-10608 (2012-08-01)
Antimicrobial peptides (AMPs), such as cecropin A from silk moth, are key components of the innate immune system. They are effective defensive weapons against invading pathogens, yet they do not target host eukaryotic cells. In contrast, peptide toxins, such as
A Lanois et al.
Applied and environmental microbiology, 77(3), 1009-1020 (2010-12-07)
Photorhabdus luminescens lives in a mutualistic association with entomopathogenic nematodes and is pathogenic for insects. Variants of Photorhabdus frequently arise irreversibly and are studied because they have altered phenotypic traits that are potentially important for the host interaction. VAR* is
Muhammad Noor et al.
Journal of biotechnology, 157(1), 31-37 (2011-11-02)
Polymer based nanocompartments have potential applications in synthetic biology, medicine (drug release) and industrial biotechnology (chiral nanoreactors, multistep syntheses, selective product recovery). A step towards the aforementioned goals is the polymer membrane functionalization through covalent bonding of chemical anchors or
Junlin Zhang et al.
Protein and peptide letters, 19(10), 1076-1081 (2012-04-20)
CAMA-syn, a hybrid composed of N-terminal α-helical segment of Cecropin A(amino acid 1-8) and Magainin 2 (amino acid 1-12), is a novel small peptide with the potent antibacterial and synergistic activity without cytotoxicity. In order to test the antibacterial function
José María Cerón et al.
Peptides, 31(8), 1494-1503 (2010-05-25)
Most antimicrobial peptides have been shown to have antitumoral activity. Cecropin A, a linear 37-residue antimicrobial polypeptide produced by the cecropia moth, has exhibited cytotoxicity in various human cancer cell lines and inhibitory effects on tumor growth. In this study
Marc A Fox et al.
Peptides, 33(2), 197-205 (2012-02-01)
Antimicrobial peptides (AMPs) are a naturally occurring component of the innate immune response of many organisms and can have activity against both Gram-negative and Gram-positive bacterial species. In order to optimize and improve the direct antimicrobial effect of AMPs against
Annabeth Fieck et al.
Experimental parasitology, 125(4), 342-347 (2010-03-09)
The parasite Trypanasoma cruzi is responsible for Chagas disease and its triatomine vector, Rhodnius prolixus, has a symbiotic relationship with the soil bacterium, Rhodococcus rhodnii. R. rhodnii that was previously genetically engineered to produce the anti-microbial peptide, cecropin A was
L Silvestro et al.
Antimicrobial agents and chemotherapy, 44(3), 602-607 (2000-02-19)
The ability of cecropin A to permeabilize and depolarize the membranes of Escherichia coli ML-35p bacteria has been compared to its bactericidal activity in an extension of earlier studies performed on synthetic lipid vesicle membranes (L. Silvestro, K. Gupta, J.
Scott Matthews et al.
Parasites & vectors, 4, 77-77 (2011-05-17)
Paratransgenesis is an approach to reducing arthropod vector competence using genetically modified symbionts. When applied to control of Chagas disease, the symbiont bacterium Rhodococcus rhodnii, resident in the gut lumen of the triatomine vector Rhodnius prolixus (Hemiptera: Reduviidae), is transformed
N L Vutto et al.
Genetika, 46(12), 1626-1634 (2011-03-26)
Binary vectors for Agrobacterium-mediated transformation were constructed to express the genes for antimicrobial peptides (APs) of the cectropin-melittin type under the control of the cauliflower mosaic virus 35S RNA promoter in plants. It was shown with Escherichia coli and Agrobacterium
Mireia Bundó et al.
BMC plant biology, 14, 102-102 (2014-04-24)
Cecropin A is a natural antimicrobial peptide that exhibits rapid, potent and long-lasting lytic activity against a broad spectrum of pathogens, thus having great biotechnological potential. Here, we report a system for producing bioactive cecropin A in rice seeds. Transgenic
Xueyan Ren et al.
Bioprocess and biosystems engineering, 35(5), 761-767 (2011-11-24)
Recombinant Pichia pastoris yeasts expressing cecropin A (GS115/CEC), was evaluated for the control of the blue mold of apple caused by Penicillium expansum due to cecropin A peptide's effective antimicrobial effects on P. expansum spores by the thiazolyl blue (MTT)
Yevgeniya Antonova et al.
Insect biochemistry and molecular biology, 39(4), 303-314 (2009-06-26)
Mosquitoes transmit numerous diseases that continue to be an enormous burden on public health worldwide. Transgenic mosquitoes impervious to vector-borne pathogens, in concert with vector control and drug and vaccine development, comprise an arsenal of means anticipated to defeat mosquito-spread
In vitro efficacy of a synthetic all-d antimicrobial peptide against clinically isolated drug-resistant strains.
Yoonkyung Park et al.
International journal of antimicrobial agents, 35(2), 208-209 (2009-12-17)
Caroline Vindry et al.
The Journal of biological chemistry, 287(42), 35527-35538 (2012-08-31)
The destabilization of AU-rich element (ARE)-containing mRNAs mediated by proteins of the TIS11 family is conserved among eukaryotes including Drosophila. Previous studies have demonstrated that Tristetraprolin, a human protein of the TIS11 family, induces the degradation of ARE-containing mRNAs through
Elizabeth Cox et al.
Biochimica et biophysica acta, 1838(9), 2198-2204 (2014-05-02)
Aminoacylated phosphatidylglycerols are common lipids in bacterial cytoplasmic membranes. Their presence in Staphylococcus aureus has been linked to increased resistance to a number of antibacterial agents, including antimicrobial peptides. Most commonly, the phosphatidylglycerol headgroup is esterified to lysine, which converts
Emel Mataraci et al.
Antimicrobial agents and chemotherapy, 56(12), 6366-6371 (2012-10-17)
Methicillin-resistant Staphylococcus aureus (MRSA) strains are most often found as hospital- and community-acquired infections. The danger of MRSA infections results from not only the emergence of multidrug resistance but also the occurrence of bacteria that form strong biofilms. We investigated
Fatima Cairrao et al.
Molecular and cellular biology, 29(10), 2636-2643 (2009-03-11)
In mammals, AU-rich elements (AREs) are critical regulators of mRNA turnover. They recruit ARE-binding proteins that inhibit or stimulate rapid mRNA degradation in response to stress or developmental cues. Using a bioinformatics approach, we have identified AREs in Drosophila melanogaster
1/2